Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy by Joselyn Rojas, Valmore Bermudez, Jim Palmar, María Sofía Martínez, Luis Carlos Olivar, Manuel Nava, Daniel Tomey, Milagros Rojas, Juan Salazar, Carlos Garicano, Manuel Velasco

“…They also include the action of proinflammatory cytokines, the production of reactive oxygen species, DNA fragmentation (typical of necroptosis in type 1 diabetic patients), excessive production of islet amyloid polypeptide with the consequent endoplasmic reticulum stress, disruption in autophagy mechanisms, and protein complex formation, such as the inflammasome, capable of increasing oxidative stress produced by mitochondrial damage. …”
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Interspecific differences in the response of autotrophic microorganisms to atrazine and S-metolachlor exposure by Laura Malbezin, Nicolas Mazzella, Sébastien Boutry, Isabelle Lavoie, Soizic Morin

“…The results reveal differences in sensitivity between species after 7 days exposure to the two compounds alone and in mixture. …”
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Investigating the role of hyperexpressed HCN1 in inducing myocardial infarction through activation of the NF-κB signaling pathway by Liang Xiao, Zhang Jie, Luo Ya

“…Cell proliferation was assessed using the CCK8 assay, while apoptosis and reactive oxygen species (ROS) levels were measured by flow cytometry. …”
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CryoProtect: A Web Server for Classifying Antifreeze Proteins from Nonantifreeze Proteins by Reny Pratiwi, Aijaz Ahmad Malik, Nalini Schaduangrat, Virapong Prachayasittikul, Jarl E. S. Wikberg, Chanin Nantasenamat, Watshara Shoombuatong

“…AFPs are found across a diverse range of species and, therefore, significantly differ in their structures. …”
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Surface Modification by Combination of Dip-Pen Nanolithography and Soft Lithography for Reduction of Bacterial Adhesion by Santiago Arango-Santander, Alejandro Pelaez-Vargas, Sidónio C. Freitas, Claudia García

“…The main objective of this study was threefold: first, to create patterns at microscale on model surfaces using DPN; second, to duplicate and transfer these patterns to a real biomaterial surface using a microstamping technique; and finally, to assess bacterial adhesion to these developed patterned surfaces using the cariogenic species Streptococcus mutans. DPN was used with a polymeric adhesive to create dot patterns on model surfaces. …”
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Heteromericarpy of Heracleum sosnowskyi Manden. (Umbelliferae = Apiaceae) by K. G. Tkachenko

“…(family Umbelliferae = Apiaceae) is included in the lists of invasive species in many regions of Russia and European countries. …”
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Lipid Oxidation at the Crossroads: Oxidative Stress and Neurodegeneration Explored in <i>Caenorhabditis elegans</i> by Julia Tortajada-Pérez, Andrea del Valle Carranza, Cristina Trujillo-del Río, Mar Collado-Pérez, José María Millán, Gema García-García, Rafael Pascual Vázquez-Manrique

“…However, this essential metabolic pathway is highly susceptible to oxidative stress, which can lead to lipid peroxidation, a damaging process induced by reactive oxygen species. Lipid peroxidation generates by-products that disrupt many cellular functions, with a strong impact on proteostasis. …”
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Effects of Zearalenone on IL-2, IL-6, and IFN-γ mRNA Levels in the Splenic Lymphocytes of Chickens by Y. C. Wang, J. L. Deng, S. W. Xu, X. Peng, Z. C. Zuo, H. M. Cui, Y. Wang, Z. H. Ren

“…Zearalenone (ZEN) is an estrogenic mycotoxin produced by several Fusarium species, which can contaminate food and feed. These compounds elicit a wide spectrum of toxic effects, including the capacity to alter normal immune function. …”
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Microbiota, Prostatitis, and Fertility: Bacterial Diversity as a Possible Health Ally by Jenniffer Puerta Suárez, Walter D. Cardona Maya

“…No statistically significant differences were observed in conventional and functional seminal parameters. The species diversity in semen samples was similar in healthy men than prostatitis patients, inverted Simpson index median 5.3 (5.0–10.7) vs. 4.5 (2.1–7.8, p=0.1508). …”
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Responses to novelty in wild insular birds: comparing breeding populations in ecologically contrasting habitats by Samara Danel, Nancy Rebout, Léna Bureau, Timothée Zidat, Dora Biro, Francesco Bonadonna

“…One hypothesis that lends itself well to testing in island habitats suggests that animals frequenting highly variable environments should be motivated to approach and interact with (i.e. explore) novelty. Intra-species comparisons of populations living in ecologically different island habitats may, thus, help reveal the factors that modulate animals’ responses to novelty. …”
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Methylglyoxal Impairs Insulin Secretion of Pancreatic β-Cells through Increased Production of ROS and Mitochondrial Dysfunction Mediated by Upregulation of UCP2 and MAPKs by Jinshuang Bo, Shiya Xie, Yi Guo, Chunli Zhang, Yanming Guan, Chunmei Li, Jianxin Lu, Qing H. Meng

“…It increased reactive oxygen species (ROS) production and apoptosis rate in MIN6 or ISN-1 cells and inhibited mitochondrial membrane potential (MMP) and ATP production. …”
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QTL‐Based Evidence of Population Genetic Divergence in Male Territorial Aggressiveness of the Japanese Freshwater Threespine Stickleback by Haruka Yamazaki, Seiichi Mori, Osamu Kishida, Atsushi J. Nagano, Tomoyuki Kokita

“…In addition, there are marked variations in the degree of male reproductive territoriality within and between species. These differences are often attributed to genetic components. …”
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Trimethylamine-N-Oxide Promotes High-Glucose-Induced Dysfunction and NLRP3 Inflammasome Activation in Retinal Microvascular Endothelial Cells by Lidan Xue, Lili Huang, Yajing Tian, Xin Cao, Yu Song

“…ZO-1 expression was determined using immunofluorescence and western blotting. Reactive oxygen species (ROS) formation was assessed using DCFH-DA. …”
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In Vitro Evaluation of Probiotic Properties of Lactic Acid Bacteria Isolated from Some Traditionally Fermented Ethiopian Food Products by Guesh Mulaw, Tesfaye Sisay Tessema, Diriba Muleta, Anteneh Tesfaye

“…The four efficient probiotic LAB isolates that belonged to Lactobacillus species were identified to the strain level using 16S rDNA gene sequence comparisons and, namely, were Lactobacillus plantarum strain CIP 103151, Lactobacillus paracasei subsp. tolerans strain NBRC 15906, Lactobacillus paracasei strain NBRC 15889, and Lactobacillus plantarum strain JCM 1149. …”
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Impact of Coastal Squeeze Induced by Erosion and Land Reclamation on Salt Marsh Wetlands by Guangzhi Zhang, Jiali Gu, Hao Hu, Maoming Sun, Jie Shao, Weiliang Dong, Liang Liang, Jian Zeng

“…Coastal erosion further caused a 10.5% decline in vegetation elevation and a 46.7% increase in slope steepness, amplifying vulnerability to wave action. Native species were largely replaced by <i>Spartina alterniflora</i>, reducing ecological diversity. …”
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On three cultivated subspecies of pea (Pisum sativum L.) by O. E. Kosterin

“…A peculiar form traditionally cultivated in Egypt was described as the species Pisum jomardii Schrank and subsequently considered also in the ranks of subspecies and variety; it would better be considered as Pisum sativum L. subsp. sativum var. jomardii (Schrank) Govorov.…”
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Aloe-Emodin-Mediated Photodynamic Therapy Induces Apoptosis in Basal Cell Carcinoma Cells via Activation of ERK/JNK Signaling Pathway by Woodvine Otieno Odhiambo, Songmei Geng, Xiaopeng Wang, Xiaodong Chen, Mengting Qin, Meng Yuan, Yang Wang, Farooq Riaz, Chengcheng Liu, Yanhong Ji

“…The cell death rate and reactive oxygen species (ROS) were assessed by flow cytometry. Western blotting was used to determine the effects of AE-mediated PDT on the apoptotic proteins, Akt, and MAPK pathways. …”
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Clinical Isolates of Mycobacterium tuberculosis Differ in Their Ability to Induce Respiratory Burst and Apoptosis in Neutrophils as a Possible Mechanism of Immune Escape by María M. Romero, Luciana Balboa, Juan I. Basile, Beatriz López, Viviana Ritacco, Silvia S. de la Barrera, María C. Sasiain, Lucía Barrera, Mercedes Alemán

“…Results showed that LAM strains strongly induced apoptosis of PMN which correlated with the induction of reactive oxygen species (ROS) production and p38 activation. Interestingly, the highly prosperous multidrug-resistant M strain, belonging to the Haarlem lineage, lacked the ability to activate and to induce PMN apoptosis as a consequence of (1) a weak ROS production and (2) the contribution of antiapoptotic mechanisms mediated at least by ERK. …”
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Understanding Patterns of the Gut Microbiome May Contribute to the Early Detection and Prevention of Type 2 Diabetes Mellitus: A Systematic Review by Natalia G. Bednarska, Asta Kristine Håberg

“…The differences in the abundance of certain microbial species could serve as an early warning for a dysbiotic gut environment and could be easily modified before the onset of disease by changes in lifestyle, taking probiotics, introducing diet modifications or stimulating the vagal nerve. …”
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Molecular Identification of Fusarium proliferatum from toenails: A case report by Sazan Jamal Gharib, Nawroz Abdul-razzak Tahir

“…DNA sequence analysis and Phylogenetic tree of the amplified ITS-rDNA was used for species identification of this strain of F. proliferatum. …”
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