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8541
Loss of p53 Expression in Gastric Epithelial Cells of Helicobacter pylori-Infected Jordanian Patients
Published 2022-01-01“…H. pylori induces the production of reactive oxygen species, DNA damage, and accelerates the degradation of the tumor suppressor protein p53, which may lead to cancer development. …”
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8542
Metabolic stability and its role in the discovery of new chemical entities
Published 2019-09-01“…In the present paper, issues of compound metabolic stability will be discussed, with special emphasis on its significance, in vitro metabolic stability testing, dilemmas regarding in vitro-in vivo extrapolation of the results and some aspects relating to different preclinical species used in in vitro metabolic stability assessment of compounds.…”
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8543
A Review on Pineapple Leaves Fibre and Its Composites
Published 2015-01-01“…Although natural fibres exhibit admirable physical and mechanical properties, it varies with the plant source, species, geography, and so forth. Pineapple leave fibre (PALF) is one of the abundantly available wastes materials of Malaysia and has not been studied yet as it is required. …”
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8544
Decoding SFRP2 progenitors in sustaining tooth growth at single-cell resolution
Published 2025-02-01“…Methods Leveraging multiple single-cell datasets, we constructed a comprehensive dental pulp cell landscape to delineate tissue similarities and species-specific differences between humans and mice. …”
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8545
Age-Dependent Loss of Mitochondrial Function in Epithelial Tissue Can Be Reversed by Coenzyme Q10
Published 2018-01-01“…The accumulation of reactive oxygen species damaged mitochondrial DNA and proteins can induce mitochondrial dysfunction within the electron transport chain. …”
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8546
Metagenomic investigation of viruses in green sea turtles (Chelonia mydas)
Published 2025-01-01“…Green sea turtles are listed on the International Union for Conservation of Nature’s Red List of Threatened Species. Thus, conservation efforts, including investigation of factors affecting the health of green sea turtles, are critical. …”
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8547
Highly selective deethylation of rhodamine B: Adsorption and photooxidation pathways of the dye on the TiO2/SiO2 composite photocatalyst
Published 2003-01-01“…It is confirmed that visible light-induced photocatalytic degradation of dye proceeds on the surface of catalysts rather than in the bulk solution and active oxygen species preferentially attack the molecular portion that connects directly to the surface of catalysts. …”
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8548
An Adverse Outcome Pathway Linking Organohalogen Exposure to Mitochondrial Disease
Published 2019-01-01“…This AOP consists of two main pathways, both of which are triggered by the molecular initiating event (MIE) of excessive reactive oxygen species generation. Pathway 1 details the downstream consequences of oxidative stress, which include mitochondrial DNA damage, protein aggregation, and depolarization of the mitochondrial membrane. …”
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8549
Organogenesis and Development of Corydoras panda in Early Stage
Published 2007-07-01“… One of attractive ornamental fish species that is from Amazon, South America, is genus Corydoras. …”
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8550
The genetic diversity of reed canarygrass (Phalaris arundinaceae L.) assessed by isozyme markers
Published 2016-08-01“…High activities in different organs and tissues, as well as codominant inheritance make isozymes convenient genetic markers in various studies into ecological and population genetics, especially in plant species, like reed canarygrass, with unsequenced genome. …”
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8551
NMR probing of copper–amyloid β1–16 interactions and self-assembly
Published 2024-12-01“…Additionally, we examined the role of copper oxidation states in generating reactive oxygen species (ROS) using a 2′-7′ dichlorofluorescein diacetate (DCFDA) assay. 13C NMR data showed site-specific interactions between copper ions and Aβ1–16, with some differences observed in H2O compared to 2H2O. …”
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8552
Cranial Cruciate Ligament Desmotomies in Sheep Resulting in Peroneus Tertius Injury
Published 2021-01-01“…Traditionally performed in rats, rabbits, cats, and dogs, CCLD in sheep provides an opportunity to study the pathology and treatment of joint instability in a species whose stifle better represents the equivalent human femorotibial joint. …”
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8553
De Novo Sequencing of a Sparassis latifolia Genome and Its Associated Comparative Analyses
Published 2018-01-01“…We then performed comparative and phylogenetic analyses, which indicate that S. latifolia is closely related to a few species in the antrodia clade including Fomitopsis pinicola, Wolfiporia cocos, Postia placenta, and Antrodia sinuosa. …”
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8554
Considerations on the Use of Exogenous Fibrolytic Enzymes to Improve Forage Utilization
Published 2014-01-01“…Exogenous fibrolytic enzymes are of fungal or bacterial origin and increase nutrient availability from the cell wall, which consists of three fractions in different proportions depending on the species of forage: digestible, potentially digestible, and indigestible. …”
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8555
Evaluating Batch Imaging as a Method for Non-Lethal Identification of Freshwater Fishes
Published 2025-01-01“…Comparing taxonomist-based identifications from batch images to specimen-based identification, batch-image identification yielded an overall species-level correct-identification rate (CIR) of 49.7%, and an overall genus-level CIR of 61.2%. …”
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8556
Spatio-temporal variation in pollen collected by honey bees (Apis mellifera) in rural-urban mosaic landscapes in Northern Europe.
Published 2025-01-01“…The composition of macro- and micronutrients of pollen vary among different plant species. Honey bees are long-distance foragers, collecting nectar and pollen from plants within several kilometers of their hive. …”
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8557
Elements of reflection on education for sustainable development 30 years after the Bruntland Report
Published 2019-03-01“…All these dimensions are equally important for the welfare of the human species. The results of the study may indicate the directions of activities necessary in education for sustainable development in the 21st century. …”
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8558
Tissue-specific resistance and susceptibility to the tomato brown rugose fruit virus (ToBRFV) conferred by Solanum pennellii loci
Published 2025-01-01“…Abstract Background Plant breeding research heavily relies on wild species, which harbor valuable traits for modern agriculture. …”
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8559
Antibacterial Activity and Mechanisms of Action of Inorganic Nanoparticles against Foodborne Bacterial Pathogens: A Systematic Review
Published 2024-01-01“…Cell wall interaction and membrane penetration, reactive oxygen species production, DNA damage, and protein synthesis inhibition were some of the generalized mechanisms recognized in the current study. …”
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8560
From byssus threads to Pinna nobilis sea-silk: a fiber characterization
Published 2023-11-01“… Sea-silk is made from the byssus threads of Pinna nobilis, an endemic species found in the Mediterranean. The fibers are carefully harvested by cutting them off the mussel, after which they undergo a series of processes including washing, drying, combing, and spinning. …”
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