Cancer-specific innate and adaptive immune rewiring drives resistance to PD-1 blockade in classic Hodgkin lymphoma by Julia Paczkowska, Ming Tang, Kyle T. Wright, Li Song, Kelsey Luu, Vignesh Shanmugam, Emma L. Welsh, Jason L. Weirather, Naomi Besson, Harrison Olszewski, Billie A. Porter, Kathleen L. Pfaff, Robert A. Redd, Fathima Zumla Cader, Elisa Mandato, Jing Ouyang, Eleonora Calabretta, Gali Bai, Lee N. Lawton, Philippe Armand, Scott J. Rodig, Xiaole Shirley Liu, Margaret A. Shipp

“…Here, we utilize single-cell RNA sequencing and spatial analysis to define shared circulating and microenvironmental features of the immune response to PD-1 blockade in cHL. …”
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Spatial-Temporal Changes and Influencing Factors of Regional Technological Innovation Efficiency in China: A Three Entity Comparative Perspective by Ye Lei, Zhang Ting, Cao Xianzhong, Zeng Gang

“…Using 31 provincial-level administrative regions in China as decision-making units, this study measures and compares the spatiotemporal changes in technological innovation efficiencies and the factors influencing the technical inefficiencies of the three entities using GIS spatial analysis and Stochastic Frontier Analysis. The main findings are as follows: 1) The technological innovation efficiencies of firms, universities, and research institutes show a steady increase over the study period, with a 45%-55% improvement space. …”
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Prevalence and spatial distribution of workplace violence against emergency medical staff in China: a cross-sectional study by Ruofan ZHANG, Jing FENG, Ge QU, Xinyan LI, Zihui LEI, Yuchao SUN, Aoqi SHEN, Chuanzhu LV, Xingyue SONG, Yong GAN

“…The spatial distribution of WPV was explored based on geographic information system technology and spatial analysis methods. Data were analyzed using Stata 17.0 and GeoDa 1.18 software. …”
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Spatial profiling of endoplasmic reticulum stress markers in tumor associated cells predicts patient outcomes in pancreatic cancer by Georgia Porter, Murray D. Norris, Minoti Apte, Angelica M. Merlot

“…The correlation of high ER stress in immune cells with poor patient survival highlights the importance of the TME and the use of spatial analysis for the identification of novel biomarkers.…”
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Pooling the complex survey data across the 64 lower and middle-income countries: A study on antibiotic usage in under-five children by Md Fakrul Islam, Prosenjit Basak Arka, Mahfuzer Rohman, Md Sabbir Hossain, Md Rashed Babu, Hasin Anupama Azhari, Md Jamal Uddin

“…For geospatial analysis, we utilized ArcGIS, a powerful tool for mapping and spatial analysis. Findings: We used data from 141,018 children under five who were reported to have had fever/cough recently in 64 LMICs. …”
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Molecular uncovering of important helminth species in wild ruminants in the Czech Republic by Lucie Škorpíková, Jaroslav Vadlejch, Jana Ilgová, Radim Plhal, Jakub Drimaj, Ondřej Mikulka, Jan Magdálek, Martin Kašný, Nikol Reslová

“…Haemonchus spp. were also frequently detected, identified in 14.9% of samples (146/983), particularly in roe deer, with a prevalence of 23.2% (86/371). Spatial analysis of these nematodes across various regions of the CR revealed the extensive distribution of both A. sidemi and Haemonchus spp. in nearly all regions. …”
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Geographic variation in modern contraceptive utilization among women of reproductive age in Mozambique: a multilevel analysis by Habtu Kifle Negash, Destaye Tirite Gelaw, Mihret Getnet, Hiwot Tezera Endale, Tseganesh Asefa, Fethiya Seid Hasen, Yihun Tefera Ayenew, Nebebe Demis Baykemagn, Trualem Zeleke Yehuala, Winta Tesfaye

“…Higher usage was concentrated in Maputo and Southeastern Gaza. Spatial analysis revealed significant regional disparities, with hotspots in Maputo and Gaza, where women are 2.52 times more likely to use contraceptives, while rural areas like Cabo Delgado lag behind. …”
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Spatial modeling of rainfed wheat yield using agroclimaticmicrozonation in Kurdistan by Naseh Qaderi, Bohloul Alijani, zahra hejazizadeh, mohammad saligheh

“…The effect of variables on yield evaluated by multivariate regression. The spatial analysis of variables was performed and the spatial model of wheat yield was introduced for province and regions. …”
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L’apport de la géomatique à la connaissance de la partie terminale de l’aqueduc du Gier à Lyon by Éric Leroy

“…The available documentation was compiled and processed within the municipal archaeology department’s Geographic Information System (GIS), known as Alyas (Lyon Archaeology and Spatial Analysis).The aqueduct generally follows a straight line in the part of the route that interests us, but the topography also demands more sinuous underground sections. …”
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Agro-Ecological Assessment of Lands in Behshahr County for Lentil (Lens culinaris Medik.) Cultivation by Karim Reyahi, Hossein Kazemi, Afshin Soltani, Fardin Sadeghzadeh

“…This study was carried out with the aim of agroecological evaluation of lands in Behshahr County (Yane-Sar region) for lentil cultivation using spatial analysis of geographical information system (GIS) and analysis hierarchy process (AHP) in 2021-2022. …”
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Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

“…The machine learning analysis of the TIME had better accuracy than the human count evaluations (AUC of human count, CD8-positive lymphocyte: 0.681, FoxP3-positive lymphocytes: 0.626, PD-L1 score: 0.567).Conclusions The spatial analysis of the TIME using machine learning predicted the immunotherapy efficacy in patients with SCLC, thus supporting its role as an immunotherapy biomarker.…”
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Single-cell and spatial characterization of plasmablast-like lymphoma cells in primary central nervous system lymphoma by Hiroki Kobayashi, Ryota Chijimatsu, Yusuke Naoi, Yoshihiro Otani, Ryo Mizuta, Kentaro Fujii, Joji Ishida, Hiroyuki Murakami, Hideki Ujiie, Kazuhiro Ikeuchi, Tomohiro Urata, Keisuke Seike, Hideaki Fujiwara, Noboru Asada, Nobuharu Fujii, Ken-ichi Matsuoka, Yasuharu Sato, Yoshinobu Maeda, Daisuke Ennishi

“…B-cell receptor (BCR) analysis revealed that BCR clonotypes of the PBL signature subpopulation were shared with other subpopulations, suggesting a common origin with other lymphoma cell subtypes. Spatial analysis additionally revealed several localization patterns of PBL signature subpopulations within the tissue, indicating spatial heterogeneity. …”
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Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic... by Partha Ray, Tomoko Hayashi, Karen Messer, Stephen Schoenberger, Aaron Miller, Dennis Carson, Sara McArdle, Zbigniew Mikulski, Jayanth S Shankara Narayanan, Suna Erdem, Herve Tiriac, Minya Pu, Rebekah R White

“…Metastatic disease and immune infiltration in the liver were analyzed 14 days postprocedure using flow cytometry and multiplex immunofluorescence imaging with spatial analysis. Candidate neoantigens were identified by mutanome profiling of tumor tissue for ex vivo functional analyses.Results The combination of IRE+CD40 Ab improved median survival to greater than 35 days, significantly longer than IRE (21 days) or CD40Ab (24 days) alone (p<0.01). …”
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Land use changes, green house gas emissions, and rehabilitation model of native tree species towards sustainable management by W.C. Adinugroho, H.L. Tata, . Darwo, Y. Lisnawati, H.S. Nuroniah, R. Dewi, I. Heriansyah, . Mawazin

“…This study was depicted into 3 objectives consisted of 1) Utilize spatial analysis to examine the dynamics of peatland use change and the trajectory of peatland use, as well as to identify the drivers behind these changes; 2) describe the effects of altering peatland utilization; and 3) describe seedling performance planted on the peatland forest of Jambi province, as Tanjung Jabung Barat and Tanjung Jabung Timur.METHODS: Land-use and land-cover change analysis was carried out utilizing various map resources. …”
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Metabolically activated and highly polyfunctional intratumoral VISTA+ regulatory B cells are associated with tumor recurrence in early-stage NSCLC by Domenico Lo Tartaro, Beatrice Aramini, Valentina Masciale, Nikolaos Paschalidis, Francesco Demetrio Lofaro, Anita Neroni, Rebecca Borella, Elena Santacroce, Alin Liviu Ciobanu, Anna Valeria Samarelli, Federica Boraldi, Daniela Quaglino, Alessandra Dubini, Michele Gaudio, Gloria Manzotti, Francesca Reggiani, Federica Torricelli, Alessia Ciarrocchi, Antonino Neri, Federica Bertolini, Massimo Dominici, Pier Luigi Filosso, Franco Stella, Lara Gibellini, Sara De Biasi, Andrea Cossarizza

“…VISTA+ Bregs displayed high metabolic demand and were able to produce different cytokines, including interleukin (IL)-10, transforming growth factor (TGF)-β, IL-6, tumor necrosis factor (TNF), and granulocyte–macrophage colony-stimulating factor (GM-CSF). Spatial analysis showed colocalization of B cells with CD4+/CD8+ T lymphocytes in TME. …”
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Carbon stock dynamics of forest to oil palm plantation conversion for ecosystem rehabilitation planning by D. Frianto, E. Sutrisno, A. Wahyudi, E. Novriyanti, W.C. Adinugroho, A.S. Yunianto, H. Kurniawan, H. Khotimah, A. Windyoningrum, I.W.S. Dharmawan, H.L. Tata, S. Suharti, H.H. Rachmat, E.M. Lim

“…Additionally, it highlights their role in ecosystem restoration initiatives and the better management of forest peatland regions.METHODS: A spatial analysis was conducted on Landsat 5 and 8 satellite images by using shapefile data stored within the Google Earth Engine platform. …”
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Nécropoles multipolaires et élaboration d’un nouveau modèle socio-politique au premier âge du Fer : réflexions à partir des sites du Camp de l’Église Sud à Flaujac-Poujols (Lot) et... by Antoine Dumas

“….), the first part of this work is dedicated to the internal analysis of each cemetery. Spatial analysis was performed following a five steps protocol, which included the creation of heatmaps (1), identification of dense areas of graves (2), the construction of concave hulls (3), buffer-zones (4) and a Delaunay triangulation designed to identify potential burial alignments (5). …”
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Processing tomato (Lycopersicon esculentum Miller) yield and quality in arid regions through micro-nano aerated drip irrigation coupled with humic acid application by Jiaying Ma, Rui Chen, Yue Wen, Jinzhu Zhang, Feihu Yin, Tehseen Javed, Jiliang Zheng, Zhenhua Wang

“…Multiple regression and spatial analysis of yield, water use efficiency, and lycopene content indicated that, under micro-nano aeration, irrigation volumes between 445.700–446.833 mm, combined with 0.492–0.498 % HA, represent optimal irrigation strategies. …”
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Analysis of Foreign Tourists’ Behavioral Patterns and Perceptions in Rural Destinations by Hamdollah Sojasi Gheidari, Zahra Soleymani

“…ArcGIS was employed for spatial analysis to examine differences in tourists' perceptions and behaviors. …”
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Evaluation of Land Use Regression Models for Nitrogen Dioxide and Benzene in Four US Cities by Shaibal Mukerjee, Luther Smith, Lucas Neas, Gary Norris

“…Spatial analysis studies have included the application of land use regression models (LURs) for health and air quality assessments. …”
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