Single-molecule two- and three-colour FRET studies reveal a transition state in SNARE disassembly by NSF by Sudheer K. Cheppali, Chang Li, Wenjing Xing, Ruirui Sun, Mengyi Yang, Yi Xue, Si-Yao Lu, Jun Yao, Shan Sun, Chunlai Chen, Sen-Fang Sui

“…Abstract SNARE (soluble N-ethylmaleimide sensitive factor attachment protein receptor) proteins are the minimal machinery required for vesicle fusion in eukaryotes. …”
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Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis by Alina A. Alshevskaya, Julia A. Lopatnikova, Nadezhda S. Shkaruba, Oksana A. Chumasova, Aleksey E. Sizikov, Aleksander V. Karaulov, Vladimir A. Kozlov, Sergey V. Sennikov

“…Its activity is regulated and induced by soluble and membrane-bound receptors, respectively. …”
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Serum Leucine-Rich α2-Glycoprotein as a Biomarker for Monitoring Disease Activity in Patients with Systemic Juvenile Idiopathic Arthritis by Masaki Shimizu, Natsumi Inoue, Mao Mizuta, Yasuo Nakagishi, Akihiro Yachie

“…Results were compared with the clinical features of s-JIA and serum cytokine levels including interleukin- (IL-) 6, IL-18, and soluble tumor necrosis factor receptors I and II. …”
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Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model by Jiqing Xu, Fred de Winter, Catherine Farrokhi, Edward Rockenstein, Michael Mante, Anthony Adame, Jonathan Cook, Xin Jin, Eliezer Masliah, Kuo-Fen Lee

“…Furthermore, we showed that soluble ectodomains of both type I and type III NRG1 significantly increased expression of Aβ-degrading enzyme neprilysin (NEP) in primary neuronal cultures. …”
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Chemical and Immunological Characteristics of Aluminum-Based, Oil-Water Emulsion, and Bacterial-Origin Adjuvants by Susana Martiñón, Angel Cisneros, Sergio Villicaña, Ricardo Hernández-Miramontes, Edgar Mixcoha, Psyché Calderón-Vargas

“…Freund’s adjuvant is the most widely used oil-water emulsion adjuvant in animal trials; it stimulates inflammation and causes aggregation and precipitation of soluble protein antigens that facilitate the uptake by antigen-presenting cells (APCs). …”
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Effect of cow vermicompost on growth, fruit yield, and quality of hot pepper (Capsicum annuum var. Red chili) by Mohammad Hossein Aminifard

“…In both seasons, the highest leaf number, fruit weight, and total soluble solids are related to the third treatment (10 t ha-1 of cow vermicompost). …”
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Transcriptomic and physiological analyses reveal that cytokinin is involved in the compound leaf development of alfalfa by Hongyao Mei, Jiajun Yan, Xuexin Jia, Weilin Wang, Shuangshuang Li, Ruiqi Sun, Hongjiao Jiang, Lijun Xie, Chuanen Zhou, Shiqie Bai, Lu Han

“…Analyses of forage quality traits indicated significant differences in crude protein (CP), acid detergent fiber (ADF), crude fat (CF), water-soluble sugars (WSS), carbon content, ash composition content, and phosphorus content between Chuancao No.7 alfalfa and wild-type. …”
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Activated Protein C Does Not Alleviate the Course of Systemic Inflammation in the APCAP Trial by Lea Kyhälä, Panu Mentula, Leena Kylänpää, Eeva Moilanen, Pauli Puolakkainen, Ville Pettilä, Heikki Repo

“…In the present study, we present the time course of the patients’ plasma or serum levels of soluble markers (IL-8, IL-6, IL-10, IL-1ra, sE-selectin, PCT) and monocyte and neutrophil cell surface (CD11b, CD14, CD62L, HLA-DR) markers of systemic inflammatory response during the first 14 days after the randomization. …”
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Anti-Inflammatory Effects of Epoxyeicosatrienoic Acids by Scott J. Thomson, Ara Askari, David Bishop-Bailey

“…Epoxyeicosatrienoic acids (EETs) are generated by the activity of both selective and also more general cytochrome p450 (CYP) enzymes on arachidonic acid and inactivated largely by soluble epoxide hydrolase (sEH), which converts them to their corresponding dihydroxyeicosatrienoic acids (DHETs). …”
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TRAIL-Dependent Resolution of Pulmonary Fibrosis by David M. Habiel, Ana Paula Moreira, Ugur B. Ismailoglu, Michael P. Dunleavy, Karen A. Cavassani, Nico van Rooijen, Ana Lucia Coelho, Cory M. Hogaboam

“…Both in vivo and in vitro studies demonstrated that Gr-1+TRAIL+ bone marrow-derived myeloid cells blocked the activation of lung myofibroblasts. Although soluble TRAIL was increased in plasma from IPF patients, the presence of TRAIL+ myeloid cells was markedly reduced in IPF lung biopsies, and primary lung fibroblasts from this patient group expressed little of the TRAIL receptor-2 (DR5) when compared with appropriate normal samples. …”
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Isolation and Bioactivity Analysis of Ethyl Acetate Extract from Acer tegmentosum Using In Vitro Assay and On-Line Screening HPLC-ABTS+ System by Kwang Jin Lee, Na-Young Song, You Chang Oh, Won-Kyung Cho, Jin Yeul Ma

“…Moreover, a rapid on-line screening HPLC-ABTS+ system for individual bioactivity of the EA-soluble fraction (five phenolic compounds) was developed. …”
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Folic Acid: Sources, Chemistry, Absorption, Metabolism, Beneficial Effects on Poultry Performance and Health by Herinda Pertiwi, Mohamad Yusril Nur Mahendra, Juriah Kamaludeen

“…FA, or folate, is a water-soluble B vitamin essential in poultry, so FA intake must be available in the feed. …”
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Entecavir: stability and drug-excipient compatibility by Ariadne Botto Fiorot, Clayton Raynan dos Santos, Thiago Padovani Xavier, Taisa Shimosakai de Lira, Marcelo Antonio de Oliveira

“…Compatibility tests by HPLC showed no chemical interaction of ETV with the excipient mannitol, a soluble diluent proposed as a replacement for lactose monohydrate, with the same function in the formulation.…”
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Fiber isolated from discarded fruits and vegetables reduces valproic acid-induced hepatotoxicity in rats by Maria Rosana Ramirez, Debora Manuale, Juan Carlos Yori

“…The physicochemical analysis revealed a high total dietary fiber content, along with an appropriate soluble to insoluble fiber ratio and excellent water and fat retention capacity. …”
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Measurement of Cadmium Ion in the Presence of Metal-Binding Biopolymers in Aqueous Sample by Jian Pu, Kensuke Fukushi

“…In aqueous environment, water-soluble polymers are effectively used to separate free metal ions from metal-polymer complexes. …”
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Clinical Presentation of Preeclampsia and the Diagnostic Value of Proteins and Their Methylation Products as Biomarkers in Pregnant Women with Preeclampsia and Their Newborns by Maria Portelli, Byron Baron

“…The clinical presentation of PE and data gathered for the biochemical markers placental growth factor (PlGF), soluble Feline McDonough Sarcoma- (fms-) like tyrosine kinase-1 (sFlt-1), asymmetric dimethylarginine (ADMA), and methyl-lysine is being reviewed with the aim of providing both a clinical and biochemical understanding of how these biomarkers might assist in the diagnosis of PE or indicate its severity.…”
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Promotion of nitric oxide production: mechanisms, strategies, and possibilities by Marcos Gonzalez, Sarah Clayton, Eric Wauson, Daniel Christian, Quang-Kim Tran

“…Endothelium-derived NO activates soluble guanylate cyclase (sGC) in vascular smooth muscle cells (VSMCs), elevating cyclic GMP (cGMP), causing vasodilation. …”
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Response of Sorghum (Sorghum bicolor L.) to Residual Phosphate in Soybean-Sorghum and Maize-Sorghum Crop Rotation Schemes on Two Contrasting Nigerian Alfisols by Abdulmajeed Hamza, Ezekiel Akinkunmi Akinrinde

“…It is evident that pH and clay contents of soils as well as the rotation crop concerned influence the efficiency of finely ground soluble phosphates in crop rotation schemes.…”
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Influence of Pre- and Postharvest Summer Pruning on the Growth, Yield, Fruit Quality, and Carbohydrate Content of Early Season Peach Cultivars by Ali Ikinci

“…The SP increased the average fruit weight and soluble solids contents (SSC) more than both control and WP. …”
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Immobilization of Dextranase Using Anionic Natural Polymer Alginate as a Matrix for the Degradation of a Long-Chain Biopolymer (Dextran) by Faiza Shahid, Afsheen Aman, Shah Ali Ul Qader

“…After comparing the characteristics of the entrapped enzyme with those of the soluble one, it was observed that the characteristics were more or less the same except for the change in reaction time which was noticed to be prolonged in the case of entrapped dextranase while the change in temperature and pH optima was not observed. …”
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