Baicalin Liposome Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice via Inhibiting TLR4/JNK/ERK/NF-κB Pathway by Yu Long, Yan Xiang, Songyu Liu, Yulu Zhang, Jinyan Wan, Qiyue Yang, Mingquan Cui, Zhimin Ci, Nan Li, Wei Peng

“…However, BA has low solubility which may limit its clinical application. …”
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Efficient recovery of rare metal lanthanum from water by MOF-modified biochar: DFT calculation and dynamic adsorption by Qilan Huang, Qianru Zhang, Shuwen Zhao, Chuchen Zhang, Huixin Guan, Jianqiao Liu

“…Abstract In this research, a novel metal-organic framework-modified biochar composite (MIL-88b@BC) was created for the first time by modifying rice husk biochar using the excellent adsorption properties of metal-organic framework (MOF), as well as reducing the solubility of MOF using biochar as a substrate, aiming to improve the understanding of the adsorption characteristics of rare-earth metal recycling and to predict its adsorption mechanism. …”
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Anticancer activity of mixed Graphene/Carbone nanotubes reinforced Sulfur-Containing polyketoamine nanocomposites by Khalid A. Khan, Gadeer R. Ashour, Mahmoud A. Hussein

“…The structure and properties of the synthesized materials were comprehensively analyzed through various techniques, including Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetric Analysis (TGA), X-ray Diffraction (XRD), Gel Permeation Chromatography (GPC), and solubility testing. Morphological characteristics were examined using Field Emission Scanning Electron Microscopy (FESEM) and Transmission Electron Microscopy (TEM). …”
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Curcumin-Loaded Lipid Nanoparticles: A Promising Antimicrobial Strategy Against <i>Enterococcus faecalis</i> in Endodontic Infections by Sónia Ferreira, Liliana Grenho, Maria Helena Fernandes, Sofia A. Costa Lima

“…<b>Methods:</b> Solid lipid nanoparticles (SLNs) were prepared as a carrier for CUR, which significantly improved its solubility. SLNs made with cetyl palmitate and Tween 80 were obtained via the hot ultrasonication method. …”
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Pt/IrO x enables selective electrochemical C-H chlorination at high current by Bo Wu, Ruihu Lu, Chao Wu, Tenghui Yuan, Bin Liu, Xi Wang, Chenyi Fang, Ziyu Mi, Surani Bin Dolmanan, Weng Weei Tjiu, Mingsheng Zhang, Bingqing Wang, Zainul Aabdin, Sui Zhang, Yi Hou, Bote Zhao, Shibo Xi, Wan Ru Leow, Ziyun Wang, Yanwei Lum

“…However, the large potentials required for C(sp 3)-H bond functionalization and low water solubility of such alkanes make it challenging. Here we discover that a Pt/IrO x electrocatalyst with optimized Cl binding energy enables selective generation of Cl free radicals for C-H chlorination of alkanes. …”
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CALPHAD-aided synthesis and characterization of an Al–Co–Cr–Fe–Ni–W high-entropy alloy prepared by arc melting and spark plasma sintering by L. Fenocchio, A. Saviot, S. Gambaro, S. Le Gallet, F. Valenza, M.R. Ardigo-Besnard, G. Cacciamani

“…Contrary to the thermodynamic predictions, after equilibration and quenching, the dissolution of the μ phase was observed due to the Gibbs-Thomson effect, which enhanced W solubility in the FCC solid solution. Annealing of the SPSed alloy followed by furnace cooling, however, allowed the precipitation of μ, thanks to the slower cooling rate. …”
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Hybrid Nanocomposite Mini-Tablet to Be Applied into the Post-Extraction Socket: Matching the Potentialities of Resveratrol-Loaded Lipid Nanoparticles and Hydroxyapatite to Promote... by Viviana De Caro, Giada Tranchida, Cecilia La Mantia, Bartolomeo Megna, Giuseppe Angellotti, Giulia Di Prima

“…<b>Background/Objectives</b>: Following tooth extraction, resveratrol (RSV) can support healing by reducing inflammation and microbial risks, though its poor solubility limits its effectiveness. This study aims to develop a solid nanocomposite by embedding RSV in lipid nanoparticles (mLNP) within a hydrophilic matrix, to the scope of improving local delivery and enhancing healing. …”
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Effect of ionic strength and mixing ratio on complex coacervation of soy protein isolate/Flammulina velutipes polysaccharide by Junmiao Zhang, Hengjun Du, Ning Ma, Lei Zhong, Gaoxing Ma, Fei Pei, Hui Chen, Qiuhui Hu

“…Soy protein isolate (SPI) is a commercial protein with balanced amino acids, while the poor solubility impedes its use in traditional foods. To overcome the problem, the complex coacervation of SPI/Flammulina velutipes polysaccharide (FVP) were investigated. …”
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Gastrointestinal absorption and its regulation of hawthorn leaves flavonoids by Junwei Chow, Xiaolei Yang, Jiarong Hu, Qiuxia Yu, Yu Zhong, Xinyi Hu, Jingru Liang, Chenyang Zhu, Shiwei Yan, Longzhou Li, Haiyang Liu, Tiandian Wang, Zihan Wang, Long Gao, Guo Ma

“…They belong to BCS class III (“like” drugs with high solubility and low permeability) and displayed poor oral bioavailability.…”
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Development and Characterization of a Hydrogel Containing Chloramphenicol-Loaded Binary Ethosomes for Effective Transdermal Permeation and Treatment Acne in Rat Model by Liu RJ, Li M, Zhu Q, Liu HY, Zhang XX, Han XY, Yu MJ, Zhou JW, Han CY

“…However, because of its toxicity and poor water solubility, its use has been restricted. To overcome these limitations, the study focused on developing CAM-loaded binary ethosomes (CAM-BE) and incorporating them into a hydrogel system for transdermal delivery.Methods: CAM-BE were prepared and characterized. …”
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Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension by Liu H, Liu S, Ma P, Ma L, Liu Y, Zhao F, Zhou R

“…Hui Liu,1,&ast; Siyun Liu,1,&ast; Pengsheng Ma,1 Long Ma,1 Yuxin Liu,1 Fang Zhao,2 Ru Zhou1,3,4 1School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 2General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 4Ningxia Characteristic Traditional Chinese Medicine Modernization Engineering Technology Research Center, Ningxia Medical University, Yinchuan, 750004, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Ru Zhou, School of Pharmacy, Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email zhou-ru926@163.com Fang Zhao, General Hospital of Ningxia Medical University, Xingqing, Ningxia, Yinchuan, 750004, People’s Republic of China, Email ysj119zf@163.comObjective: This study focuses on the development and evaluation of nanostructured lipid carriers (NLCs) loaded with aloperine as a potential therapeutic approach for the treatment of pulmonary arterial hypertension.Methods: The NLCs were designed to enhance the solubility, stability, and bioavailability of aloperine, a compound with vasodilatory and anti-inflammatory properties. …”
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Advances in Quantitative Analytical Methods for Solid Drugs by Yue Tao, Yuhan Gao, Baoxi Zhang, Kun Hu, Yifei Xie, Li Zhang, Shiying Yang, Yang Lu

“…Pharmaceutical cocrystal is a new type of solid form that can improve the stability, solubility, and bioavailability of active pharmaceutical ingredients and many other physicochemical properties. …”
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HDAC6 inhibitor-loaded brain-targeted nanocarrier-mediated neuroprotection in methamphetamine-driven Parkinson's disease by Khang-Yen Pham, Shristi Khanal, Ganesh Bohara, Nikesh Rimal, Sang-Hoon Song, Thoa Thi Kim Nguyen, In-Sun Hong, Jinkyung Cho, Jong-Sun Kang, Sooyeun Lee, Dong-Young Choi, Simmyung Yook

“…However, because of its poor water solubility and short biological half-life, it faces clinical limitations. …”
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Snack products from whole-grain red sorghum flour with paprika and cocoa powders by Janić-Hajnal Elizabet, Banjac Vojislav, Filipčev Bojana, Radić Bojana, Kos Jovana, Šimurina Olivera, Cvetković Biljana

“…The following quality attributes of snacks obtained were determined: expansion ratio, bulk density, water absorption index, water solubility index, colour and texture (hardness, number of fractures, crispiness work, crispiness index). …”
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Comparative study of the effects of different lipid oxidation simulation systems on the physicochemical properties of proteins isolated from four cultivated walnut (Juglans sigilla... by Wenyun Xiong, Lixin Ding, Wendie Cui, Lei Zhao, Shengbao Cai

“…NQWPI showed a unique subunit depolymerization, and its solubility and exogenous fluorescence intensity changed significantly, whereas emulsification and particle size of XXWPI changed the most. …”
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Variation of the Side Chain Branch Position Leads to Vastly Improved Molecular Weight and OPV Performance in 4,8-dialkoxybenzo[1,2-b:4,5-b′]dithiophene/2,1,3-benzothiadiazole Copol... by Robert C. Coffin, Christopher M. MacNeill, Eric D. Peterson, Jeremy W. Ward, Jack W. Owen, Claire A. McLellan, Gregory M. Smith, Ronald E. Noftle, Oana D. Jurchescu, David L. Carroll

“…When dodecyl side chains (P1) are employed at the 4- and 8-positions of the BDT unit, we obtain a chloroform-soluble copolymer fraction with Mw of 6.3 kg/mol. …”
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Development of a Novel Co-Amorphous Curcumin and L-Arginine (1:2): Structural Characterization, Biological Activity and Pharmacokinetics by Jose Antonio Mancillas-Quiroz, Miriam del Carmen Carrasco-Portugal, Karina Mondragón-Vásquez, Juan Carlos Huerta-Cruz, Juan Rodríguez-Silverio, Leyanis Rodríguez-Vera, Juan Gerardo Reyes-García, Francisco Javier Flores-Murrieta, Jorge Guillermo Domínguez-Chávez, Héctor Isaac Rocha-González

“…<b>Results</b>: CAC12 was 1000 times more soluble than curcumin, and it was stable for 1 month at 40 °C and 75% relative humidity or for 60 min in physiological medium at pH 4.5–6.8. …”
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Ecotoxicity of lanthanides to Daphnia magna: insights from elemental behavior and speciation in a standardized test medium by Vignati, Davide A.L., Martin, Loïc A., Poirier, Laurence, Zalouk-Vergnoux, Aurore, Fouque, Chantal, Bojic, Clément, Hissler, Christophe, Cossu-Leguille, Carole

“…However, the corresponding theoretical solubility limits do not fully agree with measured concentrations at the end of the tests. …”
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Exploring the effects of cannabidiol encapsulation in liposomes on their physicochemical properties and biocompatibility by Inga Jurgelane, Karina Egle, Andra Grava, Dana Galkina, Margarita Brante, Maksims Melnichuks, Marite Skrinda-Melne, Girts Salms, Arita Dubnika

“…However, CBD’s limited water solubility and sensitivity to environmental stresses hinder its efficacy and bioavailability. …”
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Nutrient availability in tropical soils fertilized with sewage sludge and natural phosphate by Rodinei Facco Pegoraro, Jefferson Rodrigo Teixeira Silva, Leidivan Almeida Frazão, Regynaldo Arruda Sampaio, Silvana Ferreira Bicalho, Verônica Aparecida Santos Ferreira Soares

“…Purpose: The use of sewage sludge associated with natural rock-based fertilizers can increase nutrient solubility and soil fertility. From this perspective, this study evaluated changes in the chemical soil attributes and the nutrient availability rate after the application of sewage sludge, natural phosphate, and elemental sulfur in soils with different clay contents. …”
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