Leveraging Non-Covalent Adaptable Networks to Stabilize Drug-Polymer Systems in Supersaturated Solutions: A Computational and Experimental Approach by Arif Budiman, Taufik Muhammad Fakih, Sandra Megantara, Muchtaridi Muchtaridi, Diah Lia Aulifa

“…These simulations were specifically designed to incorporate the effects of NANs, highlighting their dynamic nature and potential to enhance drug stability and solubility. Simultaneously, wet lab experiments were conducted to measure the nucleation induction times and observe the crystallization behavior of RTV under varying conditions of polymer presence. …”
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Artesunate Restrains Maturation of Dendritic Cells and Ameliorates Heart Transplantation-Induced Acute Rejection in Mice through the PERK/ATF4/CHOP Signaling Pathway by Yuanyang Chen, Sihao Zheng, Zhiwei Wang, Xin Cai, Yanjia Che, Qi Wu, Shun Yuan, Xiaohan Zhong

“…Artesunate (ART) is an artemisinin derivative, with good water solubility and higher oral bioavailability. The main aim of this study was to determine the role of ART in HT mice. …”
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Physicochemical Properties and Total Carotenoid Content of High-Quality Unripe Plantain Flour from Varieties of Hybrid Plantain Cultivars by Ekpereka Oluchukwu Anajekwu, Busie Maziya-Dixon, Rahman Akinoso, Wasiu Awoyale, Emmanuel Oladeji Alamu

“…Bulk density ranged from 0.72 to 0.77 g/ml, WAC (143.59–174.08), OAC (98.07–100.66%), swelling power capacity (10.63 to 11.82%), solubility (5.58–6.71%), and dispersibility (86.50–88.00%). …”
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Improving natural red pigment production by Streptomyces phaeolivaceus strain GH27 for functionalization of textiles with in silico ADME prediction by Gehad H. El Sayed, Mohamed Fadel, Rasha Fouad, Hend M. Ahmed, Ahmed A. Hamed

“…The radar plot demonstrated ideal parameters for size, polarity, lipophilicity, solubility, and saturation, excluding flexibility. It exhibited intermediate synthetic accessibility, exceptional permeability and absorption, elevated gastrointestinal absorption, and blood–brain barrier penetration; nonetheless, it did not adhere to the medicinal chemistry rule of three. …”
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Charge-transfer complexation of coordination cages for enhanced photochromism and photocatalysis by Gen Li, Zelin Du, Chao Wu, Yawei Liu, Yan Xu, Roy Lavendomme, Shihang Liang, En-Qing Gao, Dawei Zhang

“…Zr-MOCs represent a type of robust discrete hosts for such a design, but their host-guest chemistry in solution is hampered by the limited solubility. Here, by using pyridinium-derived cationic ligands with tetrakis(3,5-bis(trifluoromethyl)phenyl)borate (BArF −) as solubilizing counteranions, we report the preparation of soluble Zr-MOCs of different shapes (1-4) that are otherwise inaccessible through a conventional method. …”
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Synergistic Antibacterial Action of Norfloxacin-Encapsulated G4 Hydrogels: The Role of Boronic Acid and Cyclodextrin by Monica-Cornelia Sardaru, Irina Rosca, Simona Morariu, Elena-Laura Ursu, Alexandru Rotaru

“…Norfloxacin (Nfx), a poorly water-soluble antibiotic, was successfully encapsulated within the hydrogel matrix through the inclusion of complex formation with <i>β</i>-CD, improving its solubility and enabling sustained, targeted release. …”
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Solidification behavior and environmental risk assessment of toxic elements on tailings from carbothermic reduction-magnetic separation of lead blast furnace slag by Jiang Z.-W., Li M.-T., Wei C., Cao Y.-L., Li X.-B., Deng Z.-G.

“…Lead blast furnace slag (LBFS) generated during lead smelting is a hazardous solid waste containing potentially toxic elements (Pb, Zn, As, and Cd) with high mobility and solubility. In this study, a process for the utilization of LBFS by carbothermic reduction-magnetic separation method is proposed. …”
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Achieving enhanced stabilization and controlled release of curcumin via cross-linked polydopamine particles by Majid Moussaei, Ebrahim Tajik, Vahid Haddadi-Asl, S. Ali Mazloumi, Helia Heydarinasab, Elahe Abdollahi, Fatemeh Haj-Sadeghi, Hanie Ahmadi, Mohammad Reza Gholizadeh

“…Molecular simulations were conducted to estimate the solubility parameters, confirming the compatibility between PDA and dextran for effective drug loading.…”
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Potential and Comparative Tablet Disintegrant Properties of Pectin Obtained from Five Okra Genotypes in Ghana by Frederick William Akuffo Owusu, Mariam El Boakye-Gyasi, Jacob Kwaku Agbenorhevi, Marcel Tunkumgnen Bayor, Kwabena Ofori-Kwakye

“…Pectin from the various genotypes exhibited good swelling indexes (˃200%), varying solubility in different solvents, and low moisture content (˂20%). …”
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Liquid chromatography-high resolution mass spectrometry based analysis of persistent mobile organic compounds in aqueous samples: Method development and optimization by Kyriaki Anagnostopoulou, Vasileios Alampanos, Eleni Evgenidou, Dimitra A. Lambropoulou

“…Persistent Mobile Organic Compounds (PMOCs) represent a critical threat to water resources due to their high solubility, resistance to degradation, and potential toxicity, posing risks to human health and ecosystems. …”
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In Vitro Bioaccessibility of Edible Seaweed Proteins from the Chilean Coast and Proteins from the Novel Seaweed-Derived Mycoprotein by Catalina Landeta-Salgado, Javiera Munizaga, María Paz González-Troncoso, Anamaría Daza-Sanchez, Irene Martínez, María Elena Lienqueo

“…The DIASSs highlighted the superior nutritional quality of the mycoprotein, particularly for lysine (0.59) and histidine (0.67). SDS-PAGE revealed soluble peptides (<25 kDa) in <i>Durvillaea</i> spp., <i>Macrocystis pyrifera</i>, and mycoproteins, whereas <i>Ulva</i> spp. proteins exhibited limited solubility due to structural aggregation. …”
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Mitigation of Mycotoxin Content by a Single-Screw Extruder in Triticale (<i>x Triticosecale</i> Wittmack) by Breda Jakovac-Strajn, Janja Babič, Lato Pezo, Vojislav Banjac, Radmilo Čolović, Jovana Kos, Jelena Miljanić, Elizabet Janić Hajnal

“…Under these conditions, the bulk density, pellet hardness, water absorption index, and water solubility index of the pellet were 0.352 g/mL, 13.7 kg, 8.96 g/g, and 14.9 g/100 g, respectively.…”
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Insights into depolymerization of chitosan using acid hydrolysis, direct photolysis, and photocatalysis: A review by Nurul Amanina A. Suhaimi, Nur Batrisyia Amirul, Alessandra Anne Hasman, Nurulizzatul Ningsheh M. Shahri, Nur Nabaahah Roslan, Harry Lik Hock Lau, Cristina Pei Ying Kong, Eny Kusrini, Anwar Usman

“…These specific applications require low molecular weight chitosan (LMWC) due to its better biodegradability, biocompatibility, bioactivity, and solubility in water when compared to as-prepared high molecular weight chitosan (HMWC) obtained from the deacetylation of chitin. …”
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Enhanced green density of binder jetted tungsten heavy alloys with an inorganic metal salt binder by Yuhua Heng, Yiwei Mao, Kunhao Feng, Jianan Zheng, Yingmi Xie, Qingsong Wei

“…The increase of capillary force and the elevated solubility of nanoparticles were the primary reasons for densification, which facilitated pore filling and dissolution-reprecipitation during liquid phase sintering, respectively. …”
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QSPR/QSAR study of antiviral drugs modeled as multigraphs by using TI’s and MLR method to treat COVID-19 disease by Ugasini Preetha P, M. Suresh, Fikadu Tesgera Tolasa, Ebenezer Bonyah

“…These properties influence the solubility, permeability, and bio availability of the drugs, which in turn affect their ability to interact with viral targets and inhibit viral replication. …”
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Radiation dosimetry performance appraisal of the optimal concentration of nitro blue tetrazolium dye in PVA composite film at low X-ray doses by Reham Albejadi, Saleh Alashrah, Yassine El-Ghoul, Zabih Ullah, Saleh A. Almatroodi

“…The preparation method was validated by XRF analysis, and the solubility of the NBT salt was excellent, with an R2 value of 0.9656. …”
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Comparative study of packaging materials developed from fish and legume protein concentrates by Evmorfia Athanasopoulou, Angeliki Katsiroumpa, Chrysavgi Gardeli, Theofania Tsironi

“…The developed films were characterized for optical, mechanical and water barrier properties, hydrophobicity (via contact angle measurement), moisture content, water solubility, and biodegradability. Results indicated that lentil and fish protein concentrates may be effectively utilized to fabricate biodegradable packaging materials with adequate moisture barrier properties and excellent optical characteristics. …”
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Highly corrosion-resistant and photocatalytic hybrid coating on AZ31 Mg alloy via plasma electrolytic oxidation with organic-inorganic integration by Talitha Tara Thanaa, Mohammad Aadil, Alireza Askari, Arash Fattah-alhosseini, Mohammad Alkaseem, Mosab Kaseem

“…Potassium hydroxide (KOH) was used to adjust the pH, improving the interaction and solubility between the organic molecules and the PEO coating. …”
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Optimization of Flaxseed Meal Protein Extraction Process and Study of Protein Structure and Functional Properties by Tingting LUO, Jingjing LI, Haiyue HU, Yajun HE, Yuzhuo LI, Lingxuan ZHAO, Lina WANG, Chen YANG, Jianming WANG

“…At pH8, FPI exhibited optimal solubility (99.52%), water-holding capacity (8.87 g/g), emulsifying activity (8.92 m2/g), and emulsion stability (122.58 min). …”
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3D-Printed Tablets of Nifurtimox: In Vitro and In Vivo Anti-<i>Trypanosoma cruzi</i> Studies by Giselle R. Bedogni, Ana Luiza Lima, Idejan P. Gross, Tatiana Prata Menezes, Andre Talvani, Marcilio Cunha-Filho, Claudio J. Salomon

“…Benznidazole and nifurtimox are the only approved drugs for treating this condition, but their low aqueous solubility may lead to erratic bioavailability. This work aimed for the first time to formulate tablets of nifurtimox by hot melt extrusion coupled with 3D printing as a strategy to increase drug dissolution and the production of tablets with dosage on demand. …”
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