Computational and GC-MS screening of bioactive compounds from Thymus Vulgaris targeting mycolactone protein associated with Buruli ulcer by Muhammad Naveed, Imran Ali, Tariq Aziz, Ayesha Saleem, Zeerwah Rajpoot, Sameera Khaleel, Ayaz Ali Khan, Mitub Al-harbi, Thamer H. Albekairi

“…The ADMET analysis predicted that the compound borneol crosses the PGP + through the Blood Brain Barrier and gastrointestinal tract without violating Lipinski’s rule of 5 having high water solubility, and log p-value of 2.29. The molecular dynamic simulation was performed and showed the Eigenvalue of 1.332692e-04. …”
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Synthesis and Characterization of Lyophilized Chitosan-Based Hydrogels Cross-Linked with Benzaldehyde for Controlled Drug Release by Fouad Damiri, Yahya Bachra, Chaimaa Bounacir, Asmae Laaraibi, Mohammed Berrada

“…In this study, chitosan-based hydrogels were produced by incorporating three drugs with a different solubility into a polymer matrix. The lyophilized chitosan salt was prepared using an innovative and less-expensive synthetic process by the freeze-drying technique. …”
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Speciation studies of potentially toxic elements within the vicinity of major dumpsites in Ile-Ife, Osun State, Nigeria by Oluwakemi O. Tovide, John A.O. Oyekunle, Odunayo T. Ore, Bukola A. Oyebode, Elizabeth O. Moseri, Abolanle S. Adekunle, Oluwasegun Oluwarotimi, Aderemi O. Ogunfowokan, Adebayo O. Eludoyin

“…The speciation analysis indicated that the water-soluble, exchangeable, and carbonate fractions contained more than 80 % of the metals, implying high solubility and bioavailability. …”
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Bibliometric analysis of rhein in the treatment of tumors by Lan Jiang, Lan Jiang, Lan Jiang, Qian Huang, Zhongquan Shi, Yi Yang

“…However, owing to its poor water solubility, in recent years, functional modification of its functional groups or production of rhein nanoparticles to enhance its bioavailability and antitumor effects has become a hot research direction in the future.…”
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Deep eutectic solvent-assisted carbon quantum dots from biomass Triticum aestivum: A fluorescent sensor for nanomolar detection of dual analytes mercury (Ⅱ) and glutathione by Shivam Khare, Neeraj Sohal, Mandeep Kaur, Banibrata Maity

“…The prepared N,Cl-CQDs showed significant properties such as excellent photostability, favorable water solubility, and high optical stability. N,Cl-CQDs were used as sensing platform for the detection of Hg2+ ions and GSH with LOD value of 39 nM and 43 nM, respectively. …”
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Effects of shrimp chitosan based edible coating on the shelf life of selected vegetables in context of attaining SDGs by Munir Ibn Mahin, Md. Harun-Ar Rashid, Abdul Rabbi Mredul

“…The intrinsic viscosity of chitosan was 20.74 dL/g with a molecular weight of 114.01 kilodaltons (kDa). The solubility of the chitosan was 99.90 % ± 0.10 % with a DD of 95.88 ± 0.70 %. …”
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Optimization of Enzymatic Hydrolysis Process, Structural Characterization and Antioxidant Activity Analysis of Gastrodia elata Polysaccharide by Yunfei HU, De ZHOU, Qinglan ZENG, Jinsong HE, Ming ZHAO, Qingyan TANG

“…However, natural polysaccharides tend to have high molecular weights, resulting in their low solubility and bioavailability. In this study, α-amylase was used to degrade polysaccharides derived from Gastrodia elata, and the enzymatic hydrolysis process was optimized based on the yield of reducing sugars. …”
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Targeted drug delivery in neurodegenerative diseases: the role of nanotechnology by Rupal Dhariwal, Rupal Dhariwal, Mukul Jain, Mukul Jain, Yaser Rafiq Mir, Abhayveer Singh, Bhavik Jain, Pankaj Kumar, Mohd Tariq, Mohd Tariq, Devvret Verma, Khemraj Deshmukh, Virendra Kumar Yadav, Tabarak Malik, Tabarak Malik

“…The multifactorial nature of these disorders necessitates innovative solutions that leverage nanomedicine to improve drug solubility, circulation time, and targeted delivery while minimizing off-target effects. …”
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Sustainable pectin extraction from Riang husk using ultrasound-assisted extraction with deep eutectic solvents and its potential in antipollution products by Manee Saelee, Hla Myo, Nuntawat Khat-udomkiri

“…Functionally, the pectin demonstrated a solubility of 53 %, a water holding capacity of 3.88 g water/g pectin, an oil holding capacity of 3.30 g oil/g pectin, and a swelling capacity of 11.77 mL/g. …”
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Physicochemical, Functional, Microbial, and Sensory Characteristics of Precooked Complementary Flour Produced from Yellow Maize Enriched with Roasted Cashew Almonds and Baobab Pulp by Wilfred Ngaha Damndja, Aurelie Solange Agume Ntso, Thérèse Josiane Ngatchic Metsagang, Hermionne Djello Nkali

“…The proximate composition (moisture content, total ash, total carbohydrate, crude protein, crude fat, and crude fiber), soluble sugar, some minerals (iron and calcium) and vitamins (A and C), the functional properties (water absorption capacity (WAC) and water solubility index (WSI)), and the microbial characteristics of formulated flours were determined. …”
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Synthesis of rhodamine-helicin fluorescent probe for colorimetric detection of Cu2+ and fluorescent recognition of Fe3+ by Jingxuan Sun, Yuxin Shao, Peng Li, Yang Yang, Chao-Ying Gao, Jinglin Liu

“…Moreover, RbHC exhibits high stability and water solubility under both acidic and neutral conditions, enabling its application in the imaging of plant tissues. …”
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Optimizing ibrutinib bioavailability: Formulation and assessment of hydroxypropyl-β-cyclodextrin-based nanosponge delivery systems by Sunitha Sampathi, Nitiraj Kulkarni, D.V.R.N. Bhikshapathi, Jagadish V. Tawade, Nainaru Tarakaramu, Rzgar Farooq Rashid, Aziz Kubaev

“…Background: The current research aims to improve the oral bioavailability of ibrutinib (IBR), a class II drug with low solubility, through the formulation of nanosponges (NSPs) that incorporate IBR, utilizing Hydroxypropyl β-cyclodextrin (HPβCD) and 1,1′-carbonyldiimidazole (CDI) as cross-linking agent. …”
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Polyethylene glycol used as a dispersant potentiates the toxicity of insecticides in mammalian cells rather than insects by Thillaichidambaram Muneeswaran, Tanya Bhatt, Su Hwan Park, Muthuchamy Maruthupandy, Minsik Kim, Vartika Mathur, Jong-Ho Lee, Min-Seok Kim, Wan-Seob Cho

“…Insecticides are used in household products with various dispersants such as polyethylene glycol (PEG) and polyoxyethylene lauryl ether (PLE) to improve solubility. Although certain effects are expected, the combination effects of insecticides and dispersants remain elusive. …”
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Enhancing decay resistance and maintaining quality of stored apples (Malus domestica ‘Golden Delicious’) through essential oil-enriched edible coatings by Atiyeh Oraee, Yahya Selahvarzi, Mona Ghazimoghadam, Bahram Abedy, Mohammad Ali Sabokkhiz

“…Research limitations: Thyme essential oil (EO) has limitations when used directly, inculding its strong odor and flavor, low stability, low water solubility, and high volatility. Originality/Value: Overall, ALV and ZMO edible coatings appear to be a viable solution for suppressing fungal infections while maintaining apple quality under both situations.…”
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In-vitro simulation methods for mechanical plaque removal: a systematic scoping review of current techniques and future directions by Johannes Herzog, Jelena Karacic, Leonardo Svellenti, Philipp Sahrmann

“…Even though some materials achieved good results in the assessment for individual criteria like water solubility, big differences could be found concerning practicability and production time, no simulation method was rated "very good" or even "good" in the overall evaluation. …”
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A review of design factors in steam and gas push for eco-friendly oil sands production and its field application in Canada by Sunghyun Kim, Hyundon Shin, Changhyup Park, Zhuoheng Chen, Kyungbook Lee

“…Nitrogen and methane are commonly used NCGs due to their low solubility in oil, but concentrations above 3 mol% typically decreases SAGP efficiency. …”
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Phytomedicine nanoformulations for Parkinson's disease by Chinthu V. Saji, K P Mohanakumar, Rajesh A Shenoi

“…When integrated with nanotechnology, phytomedicines can overcome key limitations of herbal molecules, such as poor solubility, low bioavailability, and difficulty in crossing the blood brain barrier (BBB). …”
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Study of Teakwood Quality from Community Forests in Gunungkidul. VII. Natural Subterranean Termite Resistance by Ganis Lukmandaru, Pito Wargono, Arsy Rahman Mohammad, Vendy Eko Prasetyo

“…In the combined sapwood and heartwood data, mass loss was positively associated with hot-water solubility levels and negatively with ethanol-toluene extractive content. …”
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Optimization of the enzymatic hydrolysis process for sea buckthorn leaf polysaccharides: an investigation into their enhanced physicochemical properties and antioxidant activities by Yuning An, Buyu Wang, Ziqi Meng, Yifeng Song, Yuan Wang, Wenwen Wang, Ming Xu, Xiaoping An

“…Compared to SBLP, ESBLP exhibited enhanced solubility, oil-holding capacity, and higher L (brightness), a* (redness), and b* (yellowness) values. …”
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Betalain–Chickpea Protein Particles Produced by Freeze Drying and Spray Drying: Physicochemical Aspects, Storage Stability, and In Vitro Digestion by Mary H. Grace, Roberta Targino Hoskin, Malak Alghamdi, Mary Ann Lila, Vesela I. Chalova

“…The encapsulation method affected particles’ morphology, water activity, hygroscopicity, solubility, and color. Particles captured total betalains of 9.30 ± 0.61 and 4.40 ± 0.92 mg/g for CB-SD and CB-FD, respectively. …”
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