Experimental and Numerical Investigation on Infilled Vertical Well LASER-Assisted SAGD by Ding Chao, Wu Yongbin, Yang Guo, Luo Chihui

“…The HTHP visualized phase behavior experiment results show that the mixture of low flash point solvent oil 2# with high flash point solvent oil 3# (volumetric ratio 3 : 2) has excellent high temperature oil solubility stability and is similar to water vapor phase behavior, so it is determined as the ideal formula. …”
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How Water Content Can Influence the Chemomechanical Properties and Physical Degradation under Aging of Experimental Adhesives by Stella Renata Machado Silva Esteves, Daphne Camara Barcellos, Tânia Mara da Silva, Mateus Rodrigues Silva, Tiago Moreira Bastos Campos, Elizabeth Pimentel Rosetti, César Rogério Pucci, Sérgio Eduardo de Paiva Gonçalves

“…To evaluate the physicochemical (sorption (SOR), solubility (SOL), and degree of conversion (DC)) and mechanical (flexural strength (FS), modulus of elasticity (ME), and compressive strength (CS)) properties of adhesives with different water contents (D2O). …”
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Innovative CDR grafting and computational methods for PD-1 specific nanobody design by Jagadeeswara Reddy Devasani, Girijasankar Guntuku, Nalini Panatula, Murali Krishna Kumar Muthyala, Mary Sulakshana Palla, Teruna J. Siahaan

“…Physicochemical properties, including stability and solubility, were analyzed using web-based tools, while molecular dynamics (MD) simulations assessed stability under physiological conditions. …”
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Computational antidiabetic assessment of Salvia splendens L. polyphenols: SMOTE, ADME, ProTox, docking, and molecular dynamic studies by Hatun A. Alomar, Wafaa M. El Kady, Asmaa A. Mandour, Amany A. Naim, Neveen I. Ghali, Taghreed A. Ibrahim, Noha Fathallah

“…An ADMET analysis of twelve compounds indicated that most complied with Lipinski's rule of five, demonstrating favorable oral bioavailability and safety profiles, except for two compounds, luteolin7-O-(4″,6″-di-O-α-L-rhamno-pyranosyl)-β-D-glucopyranoside and apigenin-7-O-β-D-rutinoside, which exhibited low solubility. Molecular docking studies on α-glucosidase and protein tyrosine phosphatase 1B revealed that compound 4 had the highest binding energy, surpassing that of the standard drug rosiglitazone. …”
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Comparison of Antioxidant and Alpha-Glucosidase Inhibitory Properties of Moringa peregrina and Ferulago carduchorum Leaf Extracts and Microencapsulation of Superior Plant by Shiva Nouri, Maryam Moslehishad, Seyede Marzieh Hosseini, Mina Etemadi

“…Microencapsulation was performed using three polymer coatings, and the effects of carriers were investigated on moisture content, solubility, bulk density, microencapsulation yield, particle size, antioxidant activity, and TPC. …”
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Facile Synthesis of Propranolol and Novel Derivatives by Vy Anh Tran, Nguyen Hai Tai Tran, Long Giang Bach, Trinh Duy Nguyen, Thi Thuong Nguyen, Tan Tai Nguyen, Thi Anh Nga Nguyen, The Ky Vo, Thu-Thao Thi Vo, Van Thuan Le

“…Propranolol derivatives from 2-chlorobenzoyl chloride (compound 3), 2-fluorobenzoyl chloride (compound 5), and especially acetic anhydride (compound 6) manifested high yields and significantly increased water solubility. Six semisynthetic propranolol derivatives promise to improve antioxidative and biological activities.…”
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Valorization of Underutilized Mandarin Juice Byproduct Through Encapsulation of Flavonoids Using Freeze-Drying Technique by Marija Banožić, Adrijana Filipović, Jozo Ištuk, Mario Kovač, Anita Ivanković, Nikolina Kajić, Leona Puljić, Krunoslav Aladić, Stela Jokić

“…A wide range of reconstitution parameters (water absorption index-WAI and water solubility index-WSI) suggested possible release mechanism modifications. …”
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Supercritical fluid extraction and encapsulation of Rivas (Rheum ribes) flower: Principal component analysis (PCA) by Seyyed Ali Hoseini, Mohsen Vazifedoost, Bahareh Hajirostamloo, Zohreh Didar, Mohamad Mehdi Nematshahi

“…According to the PCA, MD showed the best solubility and the lowest price, making it a cost-effective ingredient to improve the nutritional-value of food formulations. …”
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Formulation, Characterization, Antibacterial Activity, Antioxidant Activity, and Safety Evaluation of <i>Camphora longepaniculata</i> Essential Oil Nanoemulsions Through High-Press... by Yue Yan, Changhe Wei, Xin Liu, Xin Zhao, Shanmei Zhao, Shuai Tong, Guoyou Ren, Qin Wei

“…The results demonstrated that nanoemulsification improved the stability, solubility in aqueous media, and bioavailability of CLEO, thereby broadening its potential industrial applications as a natural antibacterial and antioxidant agent.…”
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Formation and structural studies of integrated membranes based on channel silicon by V. V. Bolotov, K. E. Ivlev, E. V. Knyazev, I. V. Ponomareva

“…For the electrolyte based on HF: (CH3 )2CO, the duration of etching may be longer, which is associated with a higher solubility of hydrogen in acetone than isopropanol. …”
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A detoxified TLR4 agonist inhibits tumour growth and lung metastasis of osteosarcoma by promoting CD8+ cytotoxic lymphocyte infiltration by Ryunosuke Oyama, Akira Nabeshima, Makoto Endo, Alexey Novikov, Toshifumi Fujiwara, Capucine Phelip, Nobuhiko Yokoyama, Yoshinao Oda, Martine Caroff, Yoshihiro Matsumoto, Jerome Kerzerho, Yasuharu Nakashima

“…Lipo-MP-LPS exhibited an optimal safety and solubility profile for systemic administration at an effective dose. …”
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Enhanced Expression and Bioactivity Assessment of Recombinant SUMO-Protease-1 in E. coli BL21 (DE3) via Cleavage of His6-SMT3-SDF-1 Fusion Protein by Farzad Sadri, Hossain Safarpour, Zahra Ansari, Yazdan Ebrahimpour, Mohammad Feriedouni

“…The SUMO fusion system is advantageous in improving the solubility and correct folding of proteins that are difficult to produce. …”
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Enhanced precise therapy of ROS-sensitive dual-layer shell nanoparticles loading quercetin on DSS-induced ulcerative colitis mice by Yang Bai, Danling Jiang, Boda Wu, Jiao Peng, Ji Wang, Yuhui Chen, Xi Li

“…Relative to the free form of quercetin, the dual-layer encapsulation enhanced the solubility and bioavailability of quercetin, achieved intragastric protection, and extended the resident time of quercetin in the gastrointestinal tract. …”
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Silymarin: a promising modulator of apoptosis and survival signaling in cancer by Ujjawal Sharma, Praveen Kumar Sahni, Bunty Sharma, Madhu Gupta, Damandeep Kaur, Darin Mansor Mathkor, Shafiul Haque, Sabiha Khatoon, Hardeep Singh Tuli, Astha Mishra, Faraz Ahmad

“…As efficient carriers, liposomes, polymeric micelles, lipid- and metal-based nanoparticles, increase the solubility and distribution of silymarin in target tissues. …”
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Mechanistic Insights into the Anticancer Potential of Methoxyflavones Analogs: A Review by Mohammad Aidiel, Maisarah Abdul Mutalib, Rajesh Ramasamy, Nik Nasihah Nik Ramli, Shirley Gee Hoon Tang, Siti Hajar Adam

“…While lipophilicity is crucial for drug efficacy, the excessive lipophilic effects in flavonoids can reduce water solubility and hinder drug transport to target sites. …”
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Microwave coprocessing of modafinil with Gelucire®: Thermal and compression characteristics by Derar Omari, Assayed Sallam, Iyad Rashid, Shereen M. Assaf, Faisal Akayleh, Khaldoun A. Al-Sou′od

“…As a BCS class II drug, modafinil exhibits low solubility and high permeability, with its crystalline structure significantly impacting dissolution, bioavailability, and compressibility. …”
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Pd/S cooperativity: from stoichiometric activation of Si−H bonds to catalytic hydrosilylation by Arnaud Clerc, Marceline Humbert, Sonia Mallet‐Ladeira, Dr. Karinne Miqueu, Dr. Julien Monot, Prof. Blanca Martín‐Vaca, Dr. Didier Bourissou

“…Abstract With the aim to explore metal‐ligand cooperation across Pd−S linkages, we designed a quinoline‐based PNS tridentate ligand and prepared Pd(II) complexes thereof. Optimal solubility and stability of the dicationic complex [(PNS)Pd(II)]22+ IV2 were achieved with B(C6F5)4– as counter‐anion. …”
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Effect of Composition and Processing Conditions on Selected Properties of Potato-Based Pellets and Microwave-Expanded Snacks Supplemented with Fresh Beetroot Pulp by Katarzyna Lisiecka, Agnieszka Wójtowicz, Agnieszka Sujak

“…The aim of this study was to evaluate the influence of the addition of fresh beetroot pulp in amounts from 2.5 to 30.0 g/100 g, as well as variable screw speeds (60, 80, 100 rpm) on the chemical composition, water absorption, water solubility index, density, expansion rate, and texture of potato-based pellets and expanded snacks. …”
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Simultaneously Enhanced Permeability and Selectivity of Pebax-1074-Based Mixed-Matrix Membrane for CO₂ Separation by Rujing Hou, Junwei Xie, Yawei Gu, Lei Wang, Yichang Pan

“…Both the strengthened CO₂ solubility coefficients coming from the additional CO₂ adsorption sites of amino groups in BPEI and the reinforced CO₂ diffusivity coefficients originating from the fast transport channels created by KAUST-8 led to the promising CO₂ separation performance for KAUST-8@BPEI/Pebax-1074 MMM. …”
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RUBY® – a tetravalent (2+2) bispecific antibody format with excellent functionality and IgG-like stability, pharmacology and developability properties by Barnabas Nyesiga, Mattias Levin, Anna Säll, Anna Rosén, Kim Jansson, Sara Fritzell, Karin Hägerbrand, Dietmar Weilguny, Laura von Schantz

“…The bsAbs produced are shown to, in general, contain low amounts of aggregates and display favorable solubility and stress endurance profiles. Further, compatibility with various IgG isotypes is shown and tailored Fc gamma receptor binding confirmed. …”
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