Heptamethine cyanine-based polymeric nanoparticles for photothermal therapy in HCT116 human colon cancer model by Sastiya Kampaengsri, Gong Yi Yong, Sirimongkon Aryamueang, Bongkot Ouengwanarat, Thitima Pewklang, Kantapat Chansaenpak, Sarawut Jitrapakdee, Chin-Siang Kue, Anyanee Kamkaew

“…Thus suggesting the sulfonate groups can enhance water solubility, and its nanopolymer is biocompatible and possesses superior anti-tumor efficacy.…”
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Phytosome-Enhanced Secondary Metabolites for Improved Anticancer Efficacy: Mechanisms and Bioavailability Review by Mardiana L, Milanda T, Hadisaputri YE, Chaerunisaa AY

“…It focuses on findings from preclinical and in vitro studies that examine the pharmacokinetic enhancements provided by phytosome technology when applied to secondary metabolites.Results: Phytosome-encapsulated secondary metabolites exhibit significantly improved solubility, absorption, distribution, and cellular uptake compared to non-encapsulated forms. …”
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A Study of Teak Wood Quality from Community Forests in Gunungkidul. V.Wood Chemical Properties by Ganis Lukmandaru, Arsyi Rahman Mohammad, Pito Wargono, Vendy Eko Prasetyo

“…Chemical properties tested were holocellulose, á-cellulose, hemicellulose, lignin, ethanol-toluene extractives, hot-water soluble extractives, solubility in NaOH 1%, and ash contents. …”
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Preparation and Characterization of Proteinaceous Films from Seven Mexican Common Beans (Phaseolus vulgaris L.) by Claudia Montalvo-Paquini, Raúl Avila-Sosa, Aurelio López-Malo, Enrique Palou

“…Good stability was observed since the studied polymers did not exceed 35% of the total soluble matter while protein solubilities were not greater than 3%. …”
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Characterization of Alpha Mangostin Loaded-Mesoporous Silica Nanoparticle and the Impact on Dissolution and Physical Stability by Aulifa DL, Saepudin AH, Margaretha P, Khairinisa MA, Budiman A

“…Raya Bandung-Sumedang Km. 21, Bandung, 45363, Indonesia, Email diah.lia@unpad.ac.idPurpose: Improving drug solubility is crucial in formulating poorly water-soluble drugs, especially for oral administration. …”
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Comparative Pharmacokinetic Profiles of Puerarin in Rat Plasma by UHPLC-MS/MS after Oral Administration of Pueraria lobata Extract and Pure Puerarin by Guozhe Zhang, Jianwei Ji, Mingzhong Sun, Yuqiao Ji, Hongjian Ji

“…However, due to its poor water solubility and low oral bioavailability, its clinical applications are restricted. …”
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Synthesis, Structural Characterization, and Preclinical Efficacy of a Novel Paclitaxel-Loaded Alginate Nanoparticle for Breast Cancer Treatment by Ahmed A. Markeb, Nagwa A. El-Maali, Douaa M. Sayed, Amany Osama, Mohamed A. Y. Abdel-Malek, Amen H. Zaki, Mostafa E. A. Elwanis, James J. Driscoll

“…PTX-ALG nanoparticles demonstrated increased hydrophobicity and solubility over PTX alone. Synthetically engineered PTX-ALG nanoparticles promoted cell-cycle arrest, reduced viability, and induced apoptosis in human primary patient breast cancer cells superior to those of PTX alone. …”
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Research on the Interaction between Eight Polyphenols and Arachin by Zuwei ZHANG, Rurui LI, Cong YANG, Yongyan MENG, Mingjuan SHEN, Jian SUN, Xuechun ZHANG

“…The polyphenols decreased the surface hydrophobicity and solubility of arachin, with the lowest levels dropping to 19.92 µg and 51.7%, respectively. …”
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Influence of Hydroxypropyl-β-Cyclodextrin on the Photostability of Fungicide Pyrimethanil by Carlos Fernandes, Igor Encarnação, Alexandra Gaspar, Jorge Garrido, Fernanda Borges, E. Manuela Garrido

“…The overall results point out that pyrimethanil can be successfully encapsulated by HP-β-CD, a process that can improve its solubility and photostability properties.…”
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Dissolution of Metals from Biosolid-Treated Soils by Organic Acid Mixtures by Won-Pyo Park, Bon-Jun Koo, Andrew C. Chang, Thomas E. Ferko, Jonathan R. Parker, Tracy H. Ward, Stephanie V. Lara, Chau M. Nguyen

“…Results indicate that the solubility of metals in a BSL-treated soil with 0.01 and 0.1 M OA mixtures was significantly higher than that of 0.001 M concentrations. …”
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Effects of Acid and Enzymatic Extraction on the Structure and Physicochemical Characterization of Collagen from Chinemys reevesii Skin by Dandan YU, Wenzhi WEI, Li GUAN, Wenzhuo CHEN, Hui CAO

“…The composition, structure, and physicochemical characteristics of acid-soluble collagen (ASC) and enzyme-soluble collagen (PSC) were determined using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), high-performance liquid chromatography (HPLC), circular dichroism spectrometry (CD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM), solubility, sensory evaluation, and chroma. …”
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Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice by Kamila Borowczyk, Jacek Wróblewski, Joanna Suliburska, Noriyuki Akahoshi, Isao Ishii, Hieronim Jakubowski

“…These findings provide evidence that pelage keratin is N-homocysteinylated in vivo in mammals and birds, and that this process causes keratin damage, manifested by a reduced solubility.…”
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Combining solubilization and controlled release strategies to prepare pH-sensitive solid dispersion loaded with albendazole: in vitro and in vivo studies by Dehai Su, Mingyang Bai, Chaoqun Wei, Xiangyang Long, Xuezhen Liu, Xiangguang Shen, Huanzhong Ding

“…However, despite its clinical relevance, ABZ’s oral administration presents challenges due to its poor solubility and pH sensitivity, which diminish its therapeutic effectiveness. …”
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Formulation and evaluation of hyaluronic acid and adipic acid dihydrazide modified graphene quantum dot-based nanotherapeutics for paclitaxel-targeted delivery in breast cancer by Dilip O. Morani, Pravin O. Patil

“…However, it has some drawbacks like low water solubility, a long half-life, an unregulated rate of discharge, etc. …”
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The Effect of Lipids on the Structure and Function of Egg Proteins in Response to Pasteurization by Hao Yang, Qiang Shi, Zhongliang Wang, Xiao Chen, Fangfang Min, Xuanyi Meng, Ping Tong, Yong Wu, Hongbing Chen

“…Linoleic acid substantially increased the solubility of ovalbumin and ovomucoid, while palmitic acid significantly influenced the particle size of ovalbumin and lysozyme. …”
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The solvent effect, preferential solvation of metformin hydrochloride in binary mixed solvents of methanol/ethanol + water mixtures from 278.15 K to 323.15 K by Adel Noubigh, Abdalazeem A. Omar, Manef Abderrabba

“…The influence of solvent composition on the molar fraction solubility of MET-HCl was investigated using the Kamlet-Taft linear solvation energy relationship model. …”
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An approach to cleaning methods and materials for painted alabaster by Raquel Diogo, Elena Aguado-Guardiola, Fernando Costa, João Coroado

“…This research is aimed to obtain a deeper understanding of the chemical properties of painted alabaster sculptures as well as some of their ageing mechanisms in order to design cleaning protocols which take into account the particular changing nature of these dynamic and complex systems.Materials and some chemical properties (pH, conductivity and water solubility) of the case studyhave been characterised. …”
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Adsorption of oleic acid dissolved in isopropanol–water mixtures on hydrotalcite by Agnes Fröscher, Hans Hasse

“…Adsorption isotherms are reported for oleic acid in pure isopropanol and mixtures of isopropanol and water at temperatures between 278 and 308 K. Even though the solubility of oleic acid in isopropanol is higher than in mixtures of isopropanol and water, the highest capacity of the adsorber is found for pure isopropanol. …”
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Pharmacokinetic Comparisons of Mangiferin and Mangiferin Monosodium Salt in Rat Plasma by UPLC-MS/MS by Hongbin Guo, Mengqiao Chen, Mengran Li, Mingye Hu, Baohua Chen, Chengyan Zhou

“…Mangiferin (MG) is an active component in natural medicines, and various studies have been reported on pharmacological effects, but the low solubility and bioavailability of MG limit its wide application. …”
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Improvement of the dissolution of the antineoplastic drug regorafenib through impregnation into pullulan polysaccharide using supercritical fluid technology: Optimization of the pr... by Ali Sheikhi, Sepideh Hamedi, Gholamhossein Sodeifian, Fariba Razmimanesh

“…However, its limited water solubility hinders its clinical efficacy. This study explores the impregnation of regorafenib monohydrate (REG MH) into pullulan (PULL) using supercritical carbon dioxide (scCO2), aiming to promote the oral bioavailability, water solubility and therapeutic efficacy of the drug. …”
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