Bis(7)-harmine derivatives as potential multi-target anti-Alzheimer agents by Hongtao Du, Hongtao Du, Hongtao Du, Fang Ma, Fang Ma, Yuanyuan Cao, Miaoyan Bai, Xinyi Gao, Ziyi Yang, Yang Xu, Yan Yan, Yan Yan

“…The Surflex-Dock program in Sybyl-X2.0 Software was employed for molecular docking.ResultsIn vitro studies revealed that numerous synthesized compounds exhibited potent inhibitory activity against hAChE, and hMAO-B (IC50 < 1 μM), as well as Aβ1−42 aggregation (IC50 < 20 μM). …”
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Quantification and identification of microfibers released from textiles during simulated accelerated washing by João Pinto da Costa, Ana Costa, Andréa Marinho, Alcina Pimenta, Ana Paula Fonte, Ana L. Patrício Silva, António José Fernandes, Florinda M. Costa, Damià Barceló, Lúcia H.M.L.M. Santos, Armando Duarte, Teresa Rocha-Santos

“…Furthermore, experimental results showed that special care and attention should be paid when resorting to automated software-based identification of microplastics in environmental matrices, as this may not be as accurate as previously considered, particularly for increasingly used techniques, such as pyrolysis-gas chromatography/mass spectrometry.…”
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Implementation of Accurate and Fast DNA Cytometry by Confocal Microscopy in 3D by Lennert S. Ploeger, André Huisman, Jurryt van der Gugten, Dionne M. van der Giezen, Jeroen A. M. Beliën, Abdelhadi Y. Abbaker, Hub F. J. Dullens, William Grizzle, Neal M. Poulin, Gerrit A. Meijer, Paul J. van Diest

“…The image stacks obtained with CLSM at microscope magnifications of ×40 or ×100 were analyzed off-line using in-house developed software for semi-automated 3D fluorescence quantitation. …”
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Life cycle assessment of coconut plantation, copra, and charcoal production by T. Puspaningrum, N.S. Indrasti, C. Indrawanto, M. Yani

“…Ten impacts were calculated using the Center of Environmental Science of Leiden University Impact Assessment baseline method with Simapro software.FINDINGS: This study obtained ten impact categories, not only the global warming potential impact similar to most studies of perennial crop products in Indonesia. …”
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Automated method of bronchus and artery dimension measurement in an adult bronchiectasis population by Angelina L.P. Pieters, Qianting Lv, Jennifer J. Meerburg, Tjeerd van der Veer, Eleni-Rosalina Andrinopoulou, Pierluigi Ciet, James D. Chalmers, Michael R. Loebinger, Charles S. Haworth, J. Stuart Elborn, Harm A.W.M. Tiddens

“…The aim of this study was three-fold: 1) to assess bronchus–artery (BA) dimensions using fully automated software in a cohort of BE disease patients; 2) to compare BA dimensions with semi-quantitative BEST-CT (Bronchiectasis Scoring Technique for CT) scores for BE and bronchial wall thickening; and 3) to explore the structure–function relationship between BA-method lumen dimensions and spirometry outcomes. …”
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Designing and Modeling Digital Transformation in the Automotive Industry: Leveraging the Fourth Industrial Revolution by Mohammad Saeed Mozafari Mehr, Mohammad Taghi Taghavifard

“…Qualitative data analysis was conducted using Maxqda software, while the quantitative analysis was performed using Smart PLS.   …”
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Investigating the Asymmetric Relationship between Investor Sentiments and Fluctuations in the Overall Index via the Markov Switching Method by keyvan Shahab Lavasani, Leila Shabani Rezvani, Mohammad Ebrahim Samavi

“…Eviews12 and OxMetrics8 software types were used to estimate the research model.   …”
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Critical raw material-free multi-principal alloy design for a net-zero future by Swati Singh, Mingwen Bai, Allan Matthews, Saurav Goel, Shrikrishna N. Joshi

“…A robust machine learning (ML) model was developed using a computational database of 3,608 entries, covering unary and binary materials from the Thermo-Calc 2024a software. Among various ML models, the Extra Trees Regressor (ETR) exhibited superior performance and was integrated with metaheuristic optimization techniques to identify novel MPEA compositions. …”
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Investigating the impact of couple counseling based on the CHARMS model on sexual quality of life and marital satisfaction of wives of men suffering from myocardial infarction: a r... by Delniya Ghafuri, Soheila Rabeipoor, Kamal Khademvatani, Samira Barjasteh, Atefeh Yas

“…The Independent t-test, Chi-square, Fisher’s exact test and a general linear model were used for comparing groups with SPSS software. The data analyst was blinded to the group allocation. …”
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Habitat suitability modeling for Posidonia oceanica distribution along a Mediterranean region (NW Italy) by Rachele Bordoni, Chiara Paoli, Monica Montefalcone, Alice Oprandi, Ilaria Rigo, Francesca Ruggeri, Paolo Vassallo

“…To address this need, we developed habitat suitability models (HSMs), built up using the Random Forest algorithm in R software, that assess the suitability of the environment for the presence of P. oceanica in the Ligurian Sea (NW Italy).Model response variables included potential seabed areas characterized by P. oceanica habitats on soft and rocky bottoms, down to 50 m depth. …”
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Development of machine learning models for diagnostic biomarker identification and immune cell infiltration analysis in PCOS by Wenxiu Chen, Jianliang Miao, Jingfei Chen, Jianlin Chen

“…Batch effects were corrected using the ‘sva’ package in R software. Differential expression analysis was performed to identify genes that exhibited significant differences between the two groups. …”
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Clinical Characteristics of COVID-19 in Neonates and Infants Younger Than 3 Months by Fatemeh Varshoei, Mohammad Sadegh Rezai, Roya Farhadi, Azin Hajialibeig, Saeid Mohammadi, Masoud Moradi, Fatemeh Hosseinzadeh

“…Statistical analysis was performed using SPSS software, version 22, and P<0.05 were considered statistically significant. …”
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Effects of cold-water immersion on health and wellbeing: A systematic review and meta-analysis. by Tara Cain, Jacinta Brinsley, Hunter Bennett, Max Nelson, Carol Maher, Ben Singh

“…Meta-analyses were conducted using RevMan software (version 5.4), applying random effects models to calculate standardized mean differences (SMD) between pre- and post-CWI exposure outcomes. …”
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Efficacy of Functional Endoscopic Sinus Surgery and Impact of Chronic Lung Disease on its Outcome in Patients of Chronic Rhinosinusitis by Minakshmi Karmakar, V D Prasanna Kumar Vasamsetty, Bonapart Chowdhury

“…Results were analyzed using SPSS software. Result The mean age of this study population was 35.60 years with M: F ratio 1.27:1. …”
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Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes by Jersey Heitor da S. Maués, Helem Ferreira Ribeiro, Giovanny R. Pinto, Luana de Oliveira Lopes, Letícia M. Lamarão, Carla Mariana F. Pessoa, Caroline de Fátima Aquino Moreira-Nunes, Raimundo Miranda de Carvalho, Paulo P. Assumpção, Juan A. Rey, Rommel M. Rodríguez Burbano

“…The DEGs were picked using Sailfish software, followed by Gene Set Enrichment Analysis (GSEA) and Kyoto Encyclopedia of Gene and Genome (KEGG) pathway analysis using KEGG. …”
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The prevalence and influencing factors of COVID-19 in pregnant women post-relaxation of epidemic control measures in Hunan Province, China by Yingxia Wang, Yixu Liu, Kehan Zou, Min Yang, Yinglan Wu, Donghua Xie

“…Statistical analyses were conducted using SPSS 25.0 software.ResultsAmong the 7,761 pregnant women included in the study, 5,191 (66.9%) had a positive result of SARS-CoV-2 test or related symptoms. …”
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Culturally appropriate terminologies in health research: a participatory study with pregnant and breastfeeding mothers in Uganda by Ritah Nakijoba, Adelline Twimukye, Josephine Bayigga, Aida N. Kawuma, Simon Peter Asiimwe, Fredrick Byenume, Jacqueline Kyeyune, Sylvia Nabukenya, Francis Williams Ojara, Francis Williams Ojara, Catriona Waitt, Catriona Waitt

“…Transcription was done verbatim in English. Nvivo version 14 software was used to organize and manage the data appropriately based on themes and subthemes.ResultsA consensus on the preferred terminologies to communicate about our research studies involving pregnant and lactating mothers was reached. …”
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Enhancement of convolutional neural network for urban environment parking space classification by S. Rahman, M. Ramli, F. Arnia, R. Muharar, M. Ikhwan, S. Munzir

“…The fourth layer is composed in the same way as the third layer, but with the addition of maximum pooling. The software used in the test is Python with a Python framework.FINDINGS: The proposed architecture is the Efficient Parking Network or EfficientParkingNet. …”
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Dual disease co-expression analysis reveals potential roles of estrogen-related genes in postmenopausal osteoporosis and Parkinson’s disease by Dongdong Yu, Dongdong Yu, Jian Kang, Chengguo Ju, Qingyan Wang, Ye Qiao, Ye Qiao, Long Qiao, Long Qiao, Dongxiang Yang

“…Additionally, three hub genes—WT1, CCNB1, and SMAD7—were selected from the PPI network utilizing Cytoscape software. These three hub genes, which possess significant diagnostic value for PMO and PD, were further validated using GEO datasets. …”
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Visual analysis of research hotspots and trends in traditional Chinese medicine for depression in the 21st century: A bibliometric study based on citespace and VOSviewer by Chengcheng Song, Kelong Chen, Yongxi Jin, Ling Chen, Zuxiu Huang

“…Bibliographic information, including study authors, organisations, keywords, countries, references, citations, and co-citations, was extracted using CiteSpace and VOSviewer software for quantitative analysis, visual mapping, and scientific evaluation. …”
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