Comparison of Ziziphus jujube Mill. Syrup versus polyethylene glycol in children with functional constipation: a randomized clinical trial by Fatemeh Keihanian, Shohreh Maleknejad, Amin Saeidinia, Soheil Soltanipour, Amir Pirooz

“…Data were analyzed using SPSS software version 19 at a significance level of 0.05. …”
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Mechanism of <italic>Hindu Datura</italic> in the Treatment of Rheumatoid Arthritis from the Perspective of Network Pharmacology by Changlong FU, Yangyang MEI, Xihai LI, Zhiwei QIU, Changxing CHEN, Chunsong ZHENG

“…Objective:To construct the active component target of <italic>Hindu datura</italic> and the disease target of rheumatoid arthritis by using network pharmacology, to predict the specific molecular signal and pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis, and to analyze its potential therapeutic target and molecular mechanism.Methods:All the chemical components of <italic>hindu datura</italic> were summarized and screened through Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP)database, retrieval was performed with the preset oral bioavailability(OB)≥30%and drug like(DL)≥0.18.Uniprot database was used to screen the entire correlation basis of the effective chemical compound.After screening the disease target with"rheumatoid arthritis"as the retrieval word using GeneCards and OMIM database, the superimposed target area between the drug target of <italic>hindu datura</italic> and the disease target of rheumatoid arthritis was summarized and analyzed, and it could be used as the prediction target gene of <italic>hindu datura</italic> for treating rheumatoid arthritis.Network targets were constructed and analyzed for the exported data based on Cytoscape 3.7.1 software and STRING 7.8 database.Finally, GO functional enrichment analysis and KEGG signal pathway analysis were performed to further screen the main targets and signal pathways.Results:①Through screening and analysis, 27 effective compounds, 318 corresponding target genes and 125 predicted target genes were obtained for the treatment of rheumatoid arthritis.②The core genes in PPI network mainly included JUN, AKT1, RELA, MAPK1, etc.③GO functional enrichment analysis showed that the biological process(BP)for the treatment of rheumatoid arthritis by <italic>hindu datura</italic> mainly involves response to lipopolysaccharide, response to lipopolysaccharide, response to molecule of bacterial origin, response to metalion, response to oxidative stress, response to steroid hormone, cellular response to oxidative stress, reactive oxygen species metabolic process, response to oxygen levels, etc..The cell component(CC)consisted of membrane raft, membrane region, plasma membrane raft and presynaptic membrane; molecular functions(MF)mainly involved the nuclear receptor activity, transcription factor activity(direct ligand regulated sequence-specific DNA binding), steroid hormone receptor activity, cytokine receptors, cytokine activity, DNA-binding transcription activator activity, RNA polymeraseⅡtranscription factor binding, kinase regulator activity, receptor ligand activity, etc.The analysis of KEGG signaling pathway showed that the obvious pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis may involve IL-17 signaling pathway, TNF signal pathway, HIF-1signalpathway, Toll-like receptor signal pathway, etc.Conclusion:The potential mechanism of <italic>hindu datura</italic> for the treatment of rheumatoid arthritis is to exert anti-inflammatory, analgesic and antioxidant effects, which involve a number of interactive signal pathways.…”
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The Influence of Heavy Metals and Trace Elements on Comatose Patients with Severe Traumatic Brain Injury in the First Week of Admission by Bahia Belatar, Abdallah Elabidi, Malika Barkiyou, Mamoun El Faroudi, Rachid Eljaoudi, Laila Lahlou, Saad Kabbaj, Wajdi Maazouzi

“…Statistical analysis was performed using Statistical software (SPSS) and the cases and controls were compared using the Mann–Whitney U test and Student’s t-test for cadmium according to gender and final evolution. …”
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PCA and PSO based optimized support vector machine for efficient intrusion detection in internet of things by Mutkule Prasad Raghunath, Shyam Deshmukh, Poonam Chaudhari, Sunil L. Bangare, Kishori Kasat, Mohan Awasthy, Batyrkhan Omarov, Rajesh R. Waghulde

“…These devices has the capability to collect and disseminate information because to their integration of electronics, software, sensors, and connectivity to a network. The Internet of Things enables the remote sensing, identification, and control of physical things via the utilisation of existing network infrastructure. …”
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Effect of narrative writing based on Gibbs’ reflective model on the empathy and communication skills of nursing students by Najmeh Ahmadpour, Atefeh Shariati, Mahdieh Poodineh Moghadam

“…The obtained data were analyzed using SPSS software (version 22), applying descriptive statistics and inferential statistics at a significance level of p ≤ 0.05 and a 95% confidence interval. …”
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Rancang Bangun Aplikasi Mathgeo sebagai Media Pembelajaran Dimensi Tiga Berbasis Mobile by Santi Yunika Sufiana, Ahmad Afif Supianto, Komang Candra Brata

“…This application was built using Android Studio with the Waterfall software development life cycle. Development starts from requirement analysis, design, implementation and testing. …”
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Neuropsychological features of patients of reproductive age diagnosed with breast cancer at the stage of surgical treatment using xenon-oxygen therapy by D. A. Rozenko, A. I. Shikhlyarova, L. N. Vaschenko, N. N. Popova, Yu. Yu. Arapova, A. Yu. Ardzha, A. A. Korobov

“…Statistical data processing was performed using the Statistica 10 software package. Results. During the study, statistically significant differences were found in the assessment of subjective indicators, so in the group of patients using xenon-oxygen therapy, there was an improvement in well-being by 2.6 times, a decrease in depression by 2.3 times, a decrease in symptoms of nausea by 3 times, anxiety 1.9 times (p &lt; 0.05). …”
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Qualitative comparison of decalcifiers for mouse bone cryosections for subsequent biophotonic analysis by Shibarjun Mandal, Ramya Motganhalli Ravikumar, Astrid Tannert, Annett Urbanek, Rustam R. Guliev, Max Naumann, Sina M. Coldewey, Uta Dahmen, Lina Carvalho, Luís Bastião Silva, Ute Neugebauer

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Application of the flipped classroom model based on Bloom’s Taxonomy of Educational Objectives in endodontics education for undergraduate dental students by Yaru Wei, Zhengjun Peng

“…A teaching questionnaire was administered to evaluate the students’ mastery of theoretical knowledge, understanding of learning objectives, satisfaction of teaching method, and learning interest. The SPSS 26.0 software was used for statistical analysis, and the t-test was used to compare the differences between the two groups. …”
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Spatiotemporal variations of surface and groundwater interactions under climate and land use land cover change scenarios by Kotapati Narayana Loukika, Venkata Reddy Keesara, Eswar Sai Buri, Venkataramana Sridhar

“…In this study, the spatiotemporal variations of surface and groundwater interactions were analysed using integrated SWAT and MODFLOW model using QSWATMOD plugin in QGIS software. The surface and groundwater interactions were analysed for future periods under climate and land use land cover (LULC) change scenarios. …”
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The Effectiveness and Safety of Mesenchymal Stem Cells in the Treatment of Osteoarthritis: A Systematic Review and Meta-analysis of 28 Randomized Controlled Trials by Zhiyong Long, Mingsheng Zhang, Tianqing Zhang, Liuting Zeng, Kailin Yang, Tiejun Yang, Ganpeng Yu, Jun Li, Yang Wu, Hua Chen

“…The literature was strictly selected according to the inclusion and exclusion criteria, data was extracted, and the quality was evaluated. RevMan 5.3 software was used for meta-analysis. STATA was used to evaluate publication bias. …”
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A Method for Quantifying Mung Bean Field Planting Layouts Using UAV Images and an Improved YOLOv8-obb Model by Kun Yang, Xiaohua Sun, Ruofan Li, Zhenxue He, Xinxin Wang, Chao Wang, Bin Wang, Fushun Wang, Hongquan Liu

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Correlation and predictive value of novel anthropometric indicators with adult sarcopenia and sarcopenia obesity by Xue Wu, Ziang Chen, Yuanhui Zhao, Hong Ren

“…These indices were then cross-referenced with diagnostic assessments from dual-energy X-ray absorptiometry and bioelectrical impedance analysis to examine the correlations between various metrics and the incidence of diseases. R software (version 4.3.3) was used for analysis, and the primary analytical methods employed included logistic regression, restricted cubic splines (RCS), and the Receiver Operating Characteristic (ROC) curve analysis (AUC). …”
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Shock reaction model for impact energy release behavior of Al/PTFE reactive material by Bao-yue Guo, Ke-rong Ren, Xia-yin Ma, Gan Li, Cai-min Huang, Zhi-bin Li, Rong Chen

“…At the same time, the shock reaction model is embedded into the material library of the LS-DYNA nonlinear dynamic simulation software as a secondary development. Numerical simulations of the behavior of Al/PTFE reactive materials in several typical applications are carried out. …”
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Spatial distribution and determinants of improved shared sanitation facilities among households in Ethiopia: Using 2019 mini-Ethiopian Demographic and Health Survey. by Baye Tsegaye Amlak, Daniel Gashaneh Belay

“…The analysis included a total of 7,770 households from the weighted sample. STATA 14 software was used to clean, weigh, and analyze the data. …”
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Cryptocurrencies as a subject of financial fraud by Małgorzata Kutera

“…During the work, the VOSviewer software was also used, which enabled objective identification of the main thematic clusters based on the occurrences and link strength of keywords included in the publications. …”
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High-risk fertility behavior and associated factors among mothers attending antenatal care at public health facilities in Hossana Town, Central Ethiopia Region: facility based cros... by Yishak Sinebo, Tekle Ejajo, Awoke Girma, Tadele Yohannes

“…Data entry was done by Epi data version 4.6 and analysis was done by SPSS 25 statistical software. Variables with p-value < 0.25 in bi-variable analysis were moved to multivariable analysis for controlling the possible confounders. …”
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A physically-based formulation for texture evolution during dynamic recrystallization. A case study of ice by Chauve, Thomas, Montagnat, Maurine, Dansereau, Véronique, Saramito, Pierre, Fourteau, Kévin, Tommasi, Andréa

“…The resulting open-source software R$^{3}$iCe is validated by comparison with laboratory creep data for ice polycrystals under uniaxial compression, simple shear, and uniaxial tension. …”
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Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics by George S. Biggs, Emma E. Cawood, Aini Vuorinen, William J. McCarthy, Harry Wilders, Ioannis G. Riziotis, Antonie J. van der Zouwen, Jonathan Pettinger, Luke Nightingale, Peiling Chen, Andrew J. Powell, David House, Simon J. Boulton, J. Mark Skehel, Katrin Rittinger, Jacob T. Bush

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Patients’ Perspectives on the Preference for the Gender of Medical Professionals in Perioperative Care and Attitudes Toward Anaesthesiologists: A Cross-sectional Study by Usha Devi, Minnu Panditrao, Shilpa Bansal

“…All collected data was recorded in a Microsoft Excel sheet and analysed using Microsoft Excel software. Results: Data was collected and analysed from a total of 400 patients, of whom 207 (51.7%) were males and 193 (48.3%) were females. …”
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