Insights into the Transmission, Host Range, Genomics, Vaccination, and Current Epidemiology of the Monkeypox Virus by Yusha Araf, Jannatul Ferdous Nipa, Sabekun Naher, Sumaiya Tasnim Maliha, Hasanur Rahman, Kazi Ifthi Arafat, Mohammad Raguib Munif, Md Jamal Uddin, Nurejunnati Jeba, Sukumar Saha, Jingbo Zhai, S. M. Nazmul Hasan, Mengzhou Xue, Md. Golzar Hossain, Chunfu Zheng

“…Vaccination, particularly using the smallpox vaccine, has proven instrumental in outbreak control, exhibiting an efficacy of at least 85% against mpox as evidenced by data from Africa. …”
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Temporal and spatial characterization of keratinocytes supporting orf virus replication by Byung-Joon Seung, Sushil Khatiwada, Daniel L. Rock, Gustavo Delhon

“…While systemic poxviruses (e.g. smallpox virus, sheeppox virus) also infect other cell types, the parapoxvirus orf virus (ORFV), which causes localized infections in sheep and goats, has not been shown to replicate in cells other than keratinocytes. …”
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Challenging a paradigm: Staggered versus single-pulse mass dog vaccination strategy for rabies elimination. by Brinkley Raynor Bellotti, Elvis W Díaz, Micaela De la Puente-León, Maria T Rieders, Sergio E Recuenco, Michael Z Levy, Ricardo Castillo-Neyra

“…<h4>Background</h4>From smallpox to poliomyelitis, halting contagion transmission through simultaneous mass vaccination is ubiquitous and often perceived as the only possible solution. …”
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Mpox gastrointestinal manifestations: a systematic review by Rahul Ramakrishnan, Atira Shenoy, Ranganathan Madhavan, Damon Meyer

“…Other well-known viruses of the Orthopoxvirus genus include the variola virus (smallpox), cowpox virus and vaccinia virus. Although there is a plethora of research regarding the dermatological and influenza-like symptoms of mpox, particularly following the 2022 mpox outbreak, more research is needed on the gastrointestinal (GI) effects.Objectives This systematic review is to outline the GI manifestations of the monkeypox virus.Methods The authors conducted this systematic review using guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. …”
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Evaluation of pre-exposure vaccine effectiveness against mpox during the 2022–2023 mpox outbreak in the Madrid region (Spain): a test-negative design by José Francisco Barbas del Buey, Jesús Íñigo Martínez, Marcos Alonso García, Andrés Aragón Peña, Laura Montero Morales, Araceli Arce Arnáez

“…Introduction An appropriate vaccination approach is critical to control the current outbreak of mpox but there is little research providing information on its effectiveness, particularly under circumstances of limited vaccine availability.Methods Pre-exposure vaccination campaign in the Madrid region, with the modified vaccinia Ankara-Bavarian Nordic was indicated in the risk groups from 18 July 2022.To evaluate the vaccine effectiveness (VE) of a dose of third-generation smallpox vaccine against mpox in the context of pre-exposure prophylaxis, a population-based indirect cohort study (Broome method) also known as test-negative design (TND) was conducted in the Madrid region (6 751 251 inhabitants). …”
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Risk factors associated with human Mpox infection: a systematic review and meta-analysis by Nicola Luigi Bragazzi, Jianhong Wu, Jude Dzevela Kong, James Orbinski, Chigozie Louisa Jane Ugwu, Ali Asgary, Woldegebriel Assefa Woldegerima

“…Interaction with infected animals (OR=5.61, 95% CI 2.83, 11.13), HIV infection (OR=4.46, 95% CI 3.27, 6.08), other sexually transmitted infections (OR=1.76, 95% CI 1.42, 2.19), unprotected sexual activities (OR=1.53, 95% CI 1.13, 2.07), contact with an infected person (OR=2.39, 95% CI 1.87, 3.05), identification as men who have sex with men (OR=2.18, 95% CI 1.88, 2.51) and having multiple sexual partners (OR=1.61, 95% CI 1.24, 2.09) were associated with increased Mpox infection risk. Conversely, smallpox vaccination was associated with a significantly reduced risk of Mpox infection (OR=0.24, 95% CI 0.11, 0.55).Conclusion Identification of risk factors associated with Mpox provides insights for strategic public health planning, enabling targeted interventions for high-risk groups and optimising resource allocation to strengthen Mpox control efforts.…”
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Preparation and application evaluation of monoclonal antibodies against Monkeypox virus A29 protein by Ai Xiangjun, Zhang Xinlan, Xu Ye, Tan Chufan, Tan Chufan, Duan Chen, Liao Nami, Liu Junxi, Qiu Yilan, Qiu Yilan, Hou Defu, Hou Defu, Wang Qinglin, Wang Qinglin, Liu Rushi, Liu Rushi

“…It causes symptoms similar to Smallpox virus and is a zoonotic virus with widespread prevalence. …”
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Dynamic analysis and optimal control of a hybrid fractional monkeypox disease model in terms of external factors by Saima Rashid, Abdul Bariq, Ilyas Ali, Sobia Sultana, Ayesha Siddiqa, Sayed K. Elagan

“…The disease is similar to smallpox, but it is usually less dangerous. This study examines the evolution of the MPXV epidemic in Canada with an emphasis on the effects of control employing actual data. …”
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“If that would have lessened my symptoms, that would have been great...”: a qualitative study about the acceptability of tecovirimat as treatment for mpox by Sara Paparini, Rosalie Hayes, Benjamin Weil, Will Nutland, Ismael Maatouk, Teodora Wi, Chloe M. Orkin, Rosamund Lewis

“…Abstract Background Tecovirimat, an antiviral treatment for smallpox, was approved as a treatment for mpox by the European Medicines Agency in January 2022. …”
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Systematic review: characteristics of myocarditis followed by fixed drug eruption and dry eye syndrome in patients who have been vaccinated with monkeypox in children and adults by R. Mohamad Javier, Stephanie Angela Prijanto, Vallexa Septina Yora, Desak Gede Yuliana Eka Pratiwi, Errini Sabilla Lilhawa Ditsi, Bella Adelia, Verika Christabela Tansuri, Hendry Wijaya, Georaldhy Yussufy Caecarma, Intan Trikumala Damayanti, Anisa Ramadhanti, Atika Rahmaputri, Chabib Fachry Albab, Afif Ferdian, Fatih Farabi, Fadila Risang Ayu, Ni Putu Ika Regina Maharani, Andika Prasetyo Arifin, Eko Setyo Herwanto, Saidah Rahmat A, Safira Dita Arviana, Syifa Nur Lathifah, Nanda Rizki Yulinar, Laksmitha Saktiono Safitri, Basyar Adnani, M. Rizki Fazrian Danu, Natasya Naomi, Dayu Dwi Deria, Aulia Syifa, Panca Andana, Adrian Prasetya, Fachira Rachel Agfata, Magistra Cylvia Margaretha, Subandono Bambang Indrasto, Sukirman, Rachmanto, Hayatun Nufus, Pertiwi Febriana Chandrawati, Aan Dwi Prasetyo, Lucky Sutanto, Moch Aleq Sander

“…MPOX infection shares clinical similarities with smallpox but can cause complications like myocarditis, anorectal pain, ocular lesions, kidney damage, or soft tissue superinfection. …”
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