Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism by Michelle C.D. Bridi, Nancy Luo, Grace Kim, Benjamin J. Menarchek, Rachel A. Lee, Bryan Rodriguez, Daniel Severin, Christian Wesselborg, Caroline O’Ferrall, Ruchit Patel, Sarah Bertrand, Sujatha Kannan, Alfredo Kirkwood, Cristian Moreno, Altagracia Contreras

“…Phenotypes in both models associate with differences the timing of excitatory and inhibitory synaptic transmission and endocannabinoid signaling compared to wild type mice, but not with altered sleep. These findings raise the possibility that ASD-related phenotypes may be produced by a mismatch between E/I and behavioral state, rather than alterations to overall E/I levels per se.…”
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Safety and tolerability of intramuscular sotrovimab administered at different injection sites: results from the Phase 1 COSMIC study by Jennifer Moore, Alicia Aylott, Wen-Hung Chen, Jerzy Daniluk, Ian A. Hawes, Sergio Parra, Prosenjit Sarkar, Yasmin Sanchez-Pearson, Megan Turner, Amanda Peppercorn, Andrew Skingsley

“…No or little impact on sleep and movement was reported. Sotrovimab IM was generally well tolerated at all injection sites, at volumes up to 5 mL (dorsogluteal and anterolateral thigh) and as one 2.5 mL injection into each deltoid muscle. …”
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Estimating population attributable risk fraction of determinants of pediatric obesity by Maryam Yazdi, Ibrahim Abdollahpour, Mostafa Qorbani, Saba Karimi, Mohammad Esmail Motlagh, Majid Khademian, Roya Kelishadi

“…In addition to physical examination, a self-administered questionnaire was completed to obtain the study variables including dietary behavior, physical activity, screen time, sleep duration, socioe-conomic status (SES), and passive smoking. …”
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Relationship between Family and Myopia: Based on the Jiangsu School Student Myopia Study by Xiyan Zhang, Wenyi Yang, Jie Yang, Wei Du, Yao Xiang, Xin Wang, Chao Huang, Yan Wang, Fengyun Zhang

“…The interaction effect of the family type and region, physical examination, lifestyle (including diet habits, near work, outdoor activities, and sleep), and types of lamps and whether scolded by parents can have a significant impact on myopia. …”
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Effectiveness of the self-fatigue assessment in guiding early postoperative ambulation in gynaecological oncology patients: study protocol for a randomised controlled trial by Bo Chen, Xu Wang, Hong He, Xiaojie Huang, Qian Du, Shaoyong Xu, Xiaomin Qin, Tongting Kang

“…Secondary outcome measures are the time to first bowel movement, the incidence of moderate to severe bloating, the incidence of bowel obstruction or venous thromboembolism, the incidence of adverse events (nausea, vomiting, dizziness), patient satisfaction, sleep quality scores, patient compliance with activities, hospital costs and days in hospital.Ethics and dissemination This study was approved by the Independent Ethics Committee of Xiangyang Central Hospital affiliated with Hubei University of Arts and Sciences and registered with the China Clinical Trials Registry in May 2021. …”
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Development of the Whole Day Matters Toolkit for Primary Care: a consensus-building study to mobilize national public health guidelines in practice by Tamara L. Morgan, Michelle S. Fortier, Rahul Jain, Kirstin N. Lane, Kaleigh Maclaren, Taylor McFadden, Jeanette Prorok, Jill Robison, Zachary J. Weston, Jennifer R. Tomasone

“… IntroductionStrategic knowledge mobilization efforts are needed to enhance uptake and use of the Canadian 24-Hour Movement Guidelines (24HMG), which describe optimal amounts of physical activity, sedentary behaviour and sleep each day for overall health. The Whole Day Matters Toolkit for Primary Care is an evidence-informed resource to help primary care providers (PCPs) disseminate the 24HMGs. …”
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Adherence to Mediterranean-Like Dietary Pattern in Association with Gastroesophageal Reflux Disease in Adolescents by Azam AhmadiVasmehjani, Sara Beigrezaei, Zahra Nafei, Nasrin Behniafard, Zahra Darabi, Amin Salehi-Abargouei, Majid Aflatoonian

“…Results: The results showed that after controlling for potential confounding variables including age, sex, watching TV and computer, and BMI, the adolescents in the highest adherence to the Mediterranean style diet (MedDiet) score had lower odds of GERD [odds ratio (OR)=0.53; 95% CI 0.35-0.80, Ptrend=0.005)], sense of reflux (OR=0.45; 95% CI 0.26-0.77, Ptrend=0.01) and poor sleep (OR=0.54; 95% CI 0.31-0.96, Ptrend=0.02) compared with those in the lowest adherence. …”
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Construction of machine learning-based models for screening the high-risk patients with gastric precancerous lesions by Shuxian Yu, Haiyang Jiang, Jing Xia, Jie Gu, Mengting Chen, Yan Wang, Xiaohong Zhao, Zehua Liao, Puhua Zeng, Tian Xie, Xinbing Sui

“…According with the predictive results, the top 10 key risk factors were age, traditional Chinese medicine (TCM) constitution type, tongue coating color, tongue color, irregular meals, pickled food, greasy fur, over-hot eating habit, anxiety and sleep onset latency. These factors are all significant risk indicators for the progression of PLGC patients to GC patients. …”
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Twelve barriers to COPD diagnosis in France: a comparative qualitative study by Maxime Patout, Laurie Fraticelli, Maéva Zysman, Olivier Le Rouzic, Elisabetta Scanferla, Clémence Martin, Mathieu Delorme, Cécilia Nocent-Ejnaini, Guillaume Roucoux, Lize Kiakouama Maleka, Annaig Ozier, Yassine Benarbia, Lize Kiakouama, Olivier Le Rouzic, Jean-Paul Vasseur, Marie-Agnès Wiss-Laurent, Carla Zonca, Nissrine Erraji, Matthieu Chanard, Fabienne Peretz, Catherine Beseme, Antonio Correira Dos Santos, Héla Saïdi, Lynda Saïl

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The adolescent experience of hereditary angioedema: a qualitative study of disease burden and treatment experience by Lynne Broderick, April Foster, Laura Tesler Waldman, Laura Bordone, Aaron Yarlas

“…Participants described ways in which HAE impacted their daily lives, including impacts on physical, social, emotional, and cognitive functioning, in addition to sleep disturbance, school-related impacts, and a need to avoid attack triggers. …”
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A nomogram prediction model for mild cognitive impairment in non-dialysis outpatient patients with chronic kidney disease by Qin Yang, Yuhe Xiang, Guoting Ma, Min Cao, Yixi Fang, Wenbin Xu, Lin Li, Qin Li, Yu Feng, Qian Yang

“…Logistic regression analysis revealed that age, educational level, occupational status, use of smartphones, sleep disorder, and hemoglobin were independent influencing factors of MCI (all p<.05). …”
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Impact of Adjuvant Use of Midodrine to Intravenous Vasopressors: A Systematic Review and Meta-Analysis by Ahmad Al-Abdouh, Sadam Haddadin, Atul Matta, Ahmad Jabri, Mahmoud Barbarawi, Waiel Abusnina, Qais Radideh, Mohammed Mhanna, Dante A. Suffredini, Erin D. Michos

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Exploring the impact of deleterious missense nonsynonymous single nucleotide polymorphisms in the DRD4 gene using computational approaches by Dipto Kumer Sarker, Pallobi Ray, Fayad Bin Abdus Salam, Shaikh Jamal Uddin

“…Abstract Dopamine receptor D4 (DRD4) plays a vital role in regulating various physiological functions, including attention, impulse control, and sleep, as well as being associated with various neurological diseases, including attention deficit hyperactivity disorder, novelty seeking, and so on. …”
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Different rs-fMRI Data Processing Methods in the Study of Vascular Cognitive Impairment by Ying GUAN, Luwen ZHU, Feng WANG, Danna CAO, Xiaoling LI, Qiang TANG

“…If it can be detected early and treated in time, it can effectively improve prognosis of patients with VCI.Resting state functional magnetic resonance imaging(rs-fMRI)is a spontaneous neuronal activity in different brain regions at rest in a resting state where the subject is quiet, lying, without movement, closed eyes or blinking, but does not enter sleep and has no systemic thinking activity. Establish a network and functional connection between the relevant brain regions to reflect the spontaneous functional activities of the brain at rest. …”
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Effects of active video games on mental health among college students: a systematic review by Yue Zhao, Kim Geok Soh, Hazizi bin Abu Saad, Wenchao Rong, Cong Liu, Xinzhi Wang

“…Additionally, AVGs have demonstrated efficacy in improving sleep quality. Conclusion Overall, AVGs can serve as an effective intervention to reduce dysphoria and promote positive psychological states among college students, thus improving mental health. …”
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Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives by Bryan Cleal, Yanbing Chen, Mandy Wäldchen, Hanne Ballhausen, Drew Cooper, Shane O'Donnell, Christine Knoll, Niklas Krug, Klemens Raile, Tebbe Ubben, Adrian Tappe, Dana Lewis, Ingrid Willaing, Timothy Skinner, Katarina Braune

“…ResultsParticipants consistently reported improvements in glycemia, physical health, sleep quality, emotional impact on everyday life, and quality of life. …”
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Efficacy and Tolerability of Two Different Low-Volume Split-Dose Polyethylene Glycol Electrolytes Solution Bowel Preparation for Morning Colonoscopy by Hefeng Tian, Hui Li, Xuanrui Zhu, Wenlong Liu, Ying Fan, Lei Shi, Xiu Wang

“…For the comparison of the patients’ bowel tolerance, there were no statistical differences between the two groups regarding thirst, abdominal pain or abdominal discomfort, abdominal distension, dizziness or headache, anal discomfort, and sleep disturbance (P>0.05). However, regimen two had significantly less nausea, vomiting, and fatigue than regimen one (24.62% vs. 42.19%, P=0.034; 10.77% vs. 25.00%, P=0.035; 6.15% vs. 21.88%, P=0.010, respectively). …”
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Outcome measures after anterior cervical decompression and fusion surgery –non-respondents do not bias the results: A Finnish spine register (FinSpine) study by N. Klimko, N. Danner, H. Salo, A. Malmivaara, V. Leinonen, J. Huttunen

“…Outcomes were compared on neck and upper extremity pain, functional capacity, quality of life, sleep quality, return to work, regular use of pain medication, and opioid purchases 12 months after surgery. …”
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Influence of Biological Therapeutics, Cytokines, and Disease Activity on Depression in Rheumatoid Arthritis by Margarida Figueiredo-Braga, Caleb Cornaby, Alice Cortez, Miguel Bernardes, Georgina Terroso, Marta Figueiredo, Cristina Dos Santos Mesquita, Lúcia Costa, Brian D. Poole

“…A variety of psychological assessments were used to evaluate depression, anxiety, sleep, fatigue, and relationship status. Clinical values were obtained from medical records. …”
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Psychosocial, physical, cognitive and quality of life aspects in primary restless legs syndrome by I. Jarašiūnaitė, R. Kaladytė-Lokominienė

“…The syndrome is accompanied by nocturnal sleep disturbances and excessive daytime sleepiness. …”
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