Characterization of Malignant Melanoma Using Vibrational Spectroscopy by Ziad Hammody, Ranjit Kumar Sahu, Shaul Mordechai, Emanuela Cagnano, Shmuel Argov

“…Malignant melanoma, a malignant neoplasm of epidermal melanocytes is the third most common skin cancer. In many cases, melanoma develops from nevus, which is considered as the nonmalignant stage. …”
Get full text

Antimutagenic Effect of Hibiscus sabdariffa L. Aqueous Extract on Rats Treated with Monosodium Glutamate by Ana Carla Guidini Valentini Gheller, Jacqueline Kerkhoff, Gerardo Magela Vieira Júnior, Kleber Eduardo de Campos, Marina Mariko Sugui

“…H. sabdariffa is known to contain antioxidant, cholesterol-lowering, antiobesity, insulin resistance reduction, antihypertensive, and skin cancer chemopreventive properties. This study evaluated the effects of H. sabdariffa aqueous extract against cyclophosphamide (CPA, 25 mg/Kg) induced damage to DNA in male Wistar rats by micronucleus test. …”
Get full text

Therapeutic Implications of a Polymethoxylated Flavone, Tangeretin, in the Management of Cancer via Modulation of Different Molecular Pathways by El-Shaimaa A. Arafa, Noura T. Shurrab, Manal A. Buabeid

“…In addition, tangeretin is known to exhibit considerable selective toxicity to many types of cancer cell proliferation such as ovarian, brain, blood, and skin cancer. Evidence indicates that tangeretin acts through several mechanisms including growth inhibition, induction of apoptosis, autophagy, antiangiogenesis, and estrogenic-like effects. …”
Get full text

Categorizing and Determining of BI-RAD Breast Cancer Score by Using Deep Learning Techniques by Azhar Kassem Flayeh, Ali Douik

“… Breast cancer is second only to skin cancer in prevalence. Failure to detect and treat breast cancer early could be fatal. …”
Get full text

Towards autonomous robotic THz-based in vivo skin sensing: the PicoBot by Anubhav Dogra, Dominic Jones, Arturo Ignacio Hernandez Serrano, Shruti Chakraborty, Jacob Joshua Young, Benjamin George Page, Joseph Hardwicke, Pietro Valdastri, Emma Pickwell-MacPherson

“…Skin conditions including eczema, psoriasis and skin cancer affect a high percentage of the population and we have been developing a THz probe to help with their diagnosis, treatment and management. …”
Get full text

Risk of second primary malignancies among survivors of cutaneous melanoma: A nationwide population-based study in the Republic of Korea by Joon Min Jung, Do Hyung Kim, Ye-Jee Kim, Ik Jun Moon, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Chong Hyun Won

“…Additionally, specific SPMs were more common among melanoma survivors, including nonmelanoma skin cancer, oral cavity and pharyngeal cancer, renal cancer, female breast cancer, lung cancer, pancreatic cancer, and liver cancer. …”
Get full text

The interplay of sex and genotype in disease associations: a comprehensive network analysis in the UK Biobank by Vivek Sriram, Jakob Woerner, Yong-Yeol Ahn, Dokyoon Kim

“…Multiple sclerosis and osteoarthritis are central only in the female DDN, while cardiometabolic diseases and skin cancer are more prominent in the male DDN. Edge comparison indicated similar shared genetics between the two graphs relative to a random model of disease association, though notable discrepancies in embedding distances and clustering patterns imply a more expansive genetic influence on multimorbidity risk for females than males. …”
Get full text

Deep learning-based skin lesion analysis using hybrid ResUNet++ and modified AlexNet-Random Forest for enhanced segmentation and classification. by Saleem Mustafa, Arfan Jaffar, Muhammad Rashid, Sheeraz Akram, Sohail Masood Bhatti

“…Skin cancer is considered globally as the most fatal disease. …”
Get full text

Hematoxylin and Eosin-stained whole slide image dataset annotated for skin tissue segmentationMendeley Data by Anum Abdul Salam, Muhammad Zeeshan Asaf, Muhammad Usman Akram, Noah Musolff, Samavia Khan, Bassem Rafiq, Babar Rao

“…These images were grouped into 12 classes including tissues, skin cancer, and skin layers. We have also validated the dataset using SegFormer, which resulted in an overall accuracy of 0.875.…”
Get full text

Use of Flavonoids and Cinnamates, the Main Photoprotectors with Natural Origin by Alesandra R. Nunes, Ícaro G. P. Vieira, Dinalva B. Queiroz, Antonio Linkoln Alves Borges Leal, Selene Maia Morais, Débora Feitosa Muniz, João Tavares Calixto-Junior, Henrique Douglas Melo Coutinho

“…Many pathological problems are initiated by ultraviolet radiation (UVR), such as skin cancer, the most commonly diagnosed cancer worldwide. …”
Get full text

Causal Association Between Skin Microbiota and Malignant Melanoma: Genetic Insights From Mendelian Randomization by Li X, Wu S, Pan Y, Wu Z, Du Z, Xie W, Zhou Q

“…Xianglong Li,1 Shuang Wu,2 Yujie Pan,3 Ziyan Wu,3 Zhong Du,1 Wanying Xie,1 Qingyu Zhou1 1Department of Medical and Radiation Oncology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 2Department of Critical Care, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 3School of Medicine, Yichun University, Yichun, People’s Republic of ChinaCorrespondence: Qingyu Zhou, Email zqy17@foxmail.comBackground: Malignant melanoma (MM) is an extremely aggressive type of skin cancer that represents a major risk to human health. …”
Get full text

Working memory and the need for explainable AI – Scenarios from healthcare, social media and insurance by M. Liebherr, E. Gößwein, C. Kannen, A. Babiker, S. Al-Shakhsi, V. Staab, B.J. Li, R. Ali, C. Montag

“…Further, all participants were presented three AI systems scenarios of relatively different degrees of (personal) relevance and, hence, personal investment: skin cancer detection (i), the personalization of social media feeds (ii), and the amount to pay for a car insurance (iii). …”
Get full text

Sunscreen Use among a Population of Saudi University Students by Mohammed I. AlJasser, Abdullah Aljumah, Mohannad Alzaydi, Abdullah Alassaf, Suliman Alassafi, Maha T. Alassafi, Mohammed Almedlej, Emad Masuadi

“…The main reasons for using sunscreen were prevention of sunburns, dark spots, skin cancer, and overall skin darkening. Eighty percent of participants used other methods of sun protection. …”
Get full text

Efficacy of phototherapy to treat facial ageing when using a red versus an amber LED: a protocol for a randomised controlled trial by Lidiane Rocha Mota, Christiane Pavani, Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Ivone da Silva Duarte, Daniela de Fátima Teixeira da Silva

“…Clinically, the skin becomes more flaccid, thicker and hyperpigmented, while there is an early appearance of wrinkles and other skin changes, such as skin cancer. Nowadays, there are numerous treatments for ageing skin, and one of them is with the use of phototherapy, which uses light-emitting diodes (LEDs). …”
Get full text

Cobalt oxide nanoparticles induce cytotoxicity and excessive ROS mediated mitochondrial dysfunction and p53-independent apoptosis in melanoma cells by Hanan R. H. Mohamed, Basma A. Mohamed, George M. Hakeem, Shahd H. Elnawasani, Maria Nagy, Rawan Essam, Ayman Diab, Gehan Safwat

“…Abstract Nanotherapy has emerged as a promising strategy for the targeted and efficient treatment of melanoma, the most aggressive and lethal form of skin cancer, with minimized systemic toxicity. However, the therapeutic efficacy of cobalt oxide nanoparticles (Co3O4NPs) in melanoma treatment remains unexplored. …”
Get full text

Unlocking melanoma Suppression: Insights from Plasma-Induced potent miRNAs through PI3K-AKT-ZEB1 axis by Pradeep Bhartiya, Apurva Jaiswal, Manorma Negi, Neha Kaushik, Eun Ha Choi, Nagendra Kumar Kaushik

“…Introduction: Melanoma is a rare but highly malignant form of skin cancer. Although recent targeted and immune-based therapies have improved survival rates by 10–15%, effective melanoma treatment remains challenging. …”
Get full text

Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes by Chloe Wong, Jun Yan Ng, Yang Yie Sio, Fook Tim Chew

“…Various phenotypes such as wrinkling, pigmentation changes, and skin cancers have been linked to specific genetic loci. …”
Get full text

Geographical Differences in the Safety and Efficacy of Tofacitinib Versus TNFi: A Post Hoc Analysis of ORAL Surveillance by Bogdan Batko, Slawomir Jeka, Piotr Wiland, Agnieszka Zielińska, Maria Stopińska-Polaszewska, Marcin Stajszczyk, Magdalena Kosydar-Piechna, Mary Jane Cadatal, Jose L. Rivas

“…Abstract Introduction In ORAL Surveillance, incidence rates (IRs) of major adverse cardiovascular events (MACE) and malignancies (excluding non-melanoma skin cancer [NMSC]) in cardiovascular (CV)-risk-enriched patients with rheumatoid arthritis (RA) were numerically greater with tofacitinib in North America versus the rest of the world, due to underlying risk factors. …”
Get full text

Interdependence of coagulation with immunotherapy and BRAF/MEK inhibitor therapy: results from a prospective study by Malte Beckmann, Julian Schlüter, Michael Erdmann, Rafaela Kramer, Sarah Cunningham, Holger Hackstein, Robert Zimmermann, Lucie Heinzerling

“…A total of 31 patients with advanced skin cancer treated with either ICIs (n = 24) or BRAF/MEK inhibitors (n = 7) were longitudinally assessed for blood and coagulation parameters before as well as 7, 20 and 40 days after initiation of systemic tumor therapy. …”
Get full text

CD133 Antigen as a Potential Marker of Melanoma Stem Cells: In Vitro and In Vivo Studies by Tomasz Kloskowski, Joanna Jarząbkowska, Arkadiusz Jundziłł, Daria Balcerczyk, Monika Buhl, Kamil Szeliski, Magdalena Bodnar, Andrzej Marszałek, Gerard Drewa, Tomasz Drewa, Marta Pokrywczyńska

“…Melanoma is the most dangerous type of skin cancer. Cancer stem cells (CSCs) are suspected to be responsible for the cancer recurrence and in the consequence for cancer therapy failure. …”
Get full text