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    Hepatocellular carcinoma: signaling pathways and therapeutic advances by Jiaojiao Zheng, Siying Wang, Lei Xia, Zhen Sun, Kui Ming Chan, René Bernards, Wenxin Qin, Jinhong Chen, Qiang Xia, Haojie Jin

    Published 2025-02-01
    “…Investigating the key signaling pathways and their inhibitors is pivotal for achieving therapeutic advancements in the management of HCC. …”
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    Article
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    Current Views of Toll-Like Receptor Signaling Pathways by Masahiro Yamamoto, Kiyoshi Takeda

    Published 2010-01-01
    “…In terms of intracellular TLR-mediated signaling pathways, cytoplasmic adaptor molecules containing Toll/IL-1R (TIR) domains play important roles in inflammatory immune responses through the production of proinflammatory cytokines, nitric oxide, and type I interferon, and upregulation of costimulatory molecules. …”
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    An overview of breast cancer: Classification and related signaling pathways by Pit Foong Chan, Roslida Abd Hamid

    Published 2021-04-01
    “…Like any other cancers, several signaling pathways that enhance the proliferation, survival, invasion, and metastasis capability of tumor cells have been observed in breast cancer. …”
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    Article
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    Mechanisms and therapeutic potential of the hedgehog signaling pathway in cancer by Ge Cong, Xingyu Zhu, Xin Ru Chen, Hao Chen, Wei Chong

    Published 2025-02-01
    “…Thus, notably Smo inhibitors, the opening of inhibitors of the hedgehog signaling pathway has become a topic of research attention. …”
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    Article
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    Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities by Jiankun Zhu, Chandra Mohan

    Published 2010-01-01
    “…Given their important role in infectious and non-infectious disease settings, TLRs and their signaling pathways emerge as attractive targets for therapeutics.…”
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    Article
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    Nasopharyngeal Carcinoma Signaling Pathway: An Update on Molecular Biomarkers by Warut Tulalamba, Tavan Janvilisri

    Published 2012-01-01
    “…In this paper, the molecular signaling pathways in the NPC are discussed for the holistic view of NPC development and progression. …”
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    Article
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    Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment by Jeffrey Koury, Li Zhong, Jijun Hao

    Published 2017-01-01
    “…The Wnt, Hedgehog, and Notch pathways are inherent signaling pathways in normal embryogenesis, development, and hemostasis. …”
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    Article
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    The Pathogenesis of Necroptosis-Dependent Signaling Pathway in Cerebral Ischemic Disease by Yang Xu, Ji Zhang, Lingsong Ma, Shoucai Zhao, Shizun Li, Tingting Huang, Zhaohu Chu

    Published 2018-01-01
    “…Multiple inhibitors of RIPK1 and MLKL have been developed to block the cascade of signal pathways for procedural necrosis and represent potential leads for drug development. …”
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    NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis by Shin Maeda

    Published 2010-01-01
    “…A better understanding of these signaling pathways in the liver will help us understand the mechanism of hepatocarcinogenesis and provide a new therapeutic target for HCC.…”
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    Article
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