Danggui-Shaoyao-San Can Ameliorate Alzheimer’s Disease by Inhibiting Hippocampal Neuron Apoptosis: Findings from Serum Pharmacology by Zhang KX, Zhang JW, Jiang YH, Wang YR, Liu ZL, Ding PL, Wang XY, Cui WQ, Xu XQ, Wang YH

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Guar gum-modified magnetic palladium nanocatalyst: C–N coupling reaction and STAT3-Mediated breast cancer therapy by Junrui Luan, Xin Dong, Shuwen Zhou

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Targeted therapy for pancreatic ductal adenocarcinoma: Mechanisms and clinical study by Heng‐Chung Kung, Jun Yu

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Tensile force promotes osteogenic differentiation via ephrinB2-EphB4 signaling pathway in orthodontic tooth movement by Hang Yu, Xiaoxi Wei, Huan Jiang, Huichuan Qi, Yi Zhang, Min Hu

“…Further investigation into the signaling pathways revealed that TF significantly increased levels of MAPK pathways, however, when EphB4 receptor was blocked, only the promotion of p-ERK1/2 was decreased. …”
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Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway by Jiawei He, Anhui Yang, Xuyu Zhao, Yang Liu, Shuyan Liu, Di Wang

“…Altogether, GIPS can inhibit the growth of colon cancer, at least partially, via inhibiting the Wnt/β-catenin signaling pathway.…”
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LINC01355 Contributes to Malignant Phenotype of Oral Squamous Cell Carcinoma and Cytotoxic T Cell Infiltration via Activating Notch Signaling Pathway by Chen Zou, Siyuan Wu, Haigang Wei, Hailing Luo, Zhe Tang, Xia Li, Xiaozhi Lv, Yilong Ai

“…In conclusion, it was implied that LINC01355 might induce the development of OSCC via modulating the Notch signal pathway, which could provide a candidate therapeutic target for OSCC.…”
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CNP-pGC-cGMP-PDE3-cAMP Signal Pathway Upregulated in Gastric Smooth Muscle of Diabetic Rats by Ying-Lan Cai, Mo-Han Zhang, Xu Huang, Jing-Zhi Jiang, Li-Hua Piao, Zheng Jin, Wen-Xie Xu

“…The present study was designed to determine whether the upregulation of CNP-NPR-B/pGC-cGMP signal pathway affects cGMP-PDE3-cAMP signal pathway in diabetic gastric smooth muscle. …”
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TAK-242 improves sepsis-associated acute kidney injury in rats by inhibiting the TLR4/NF-κB signaling pathway by Yan-mei Xia, Yu-qian Guan, Ji-fang Liang, Wei-dong Wu

Subjects: “…toll-like receptor 4 (TLR4)/nuclear factor κB (NF-κB) signaling pathway…”
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Tribbles 3 Regulates the Fibrosis Cytokine TGF-β1 through ERK1/2-MAPK Signaling Pathway in Diabetic Nephropathy by Luwei Zhang, Jinhang Zhang, Xinnong Liu, Shengli Liu, Jun Tian

“…TRB3 may be involved in diabetic nephropathy by regulating the fibrosis cytokine TGF-β1 and collagen type IV through the ERK1/2 MAPK signaling pathway.…”
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TMEM45A enhances palbociclib resistance and cellular glycolysis by activating AKT/mTOR signaling pathway in HR+ breast cancer by Cui Chen, Zehong Chen, Jinze Zhao, Xinyun Wen, Hanming Yao, Zijin Weng, Huiping Xiong, Zongheng Zheng, Juekun Wu

“…Subsequent gene set enrichment analysis (GSEA) confirms that TMEM45A activates the AKT/mTOR signaling pathway, which is integral to cell cycle progression and glycolysis. …”
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Prediction of angiogenesis suppression by myricetin from Aeginetia indica via inhibiting VEGFR2 signaling pathway using computer-aided analysis by Marjanur Rahman Bhuiyan, Khondoker Shahin Ahmed, Md Sharif Reza, Hemayet Hossain, Syed Mumtahin Mannan Siam, Shahriar Nayan, Sarah Jafrin, Sadikur Rahman Shuvo, A.F.M.Shahid Ud Daula

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Effects of Polygonatum sibiricum Polysaccharides (PSP) on Human Esophageal Squamous Cell Carcinoma (ESCC) via NF-κB Signaling Pathway by Weizheng Zhou, Jiang Hong, Ji Zhu, Xiaowei Wang

“…These observed effects were probably due to the PSP’s inhibition on the NF-κB signaling pathway in Eca109 cells via the regulation of the TLR4 expression.…”
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Gingival fibroblast suppress the osteogenesis process mediated by bone substitute materials via WNT/β-catenin signaling pathway in vitro and in vivo by Guanqi Liu, Jiahui Lin, Xiaoyan Chen, Runheng Liu

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BRCA1 is involved in sustaining rapid antler growth possibly via balancing of the p53/endoplasmic reticulum stress signaling pathway by Qianqian Guo, Zhen Wang, Jiping Li, Chao Ma, Junjun Zheng, Hengxing Ba, Guokun Zhang, Chunyi Li

“…RNA-seq results showed that in the absence of BRCA1, the p53 signaling pathway was significantly up-regulated. Associated with this change, the cell apoptosis and cell senescence-relevant-genes, CDKN1A, CDKN2A and Fas were over expressed, but the expression of cell-cycle-progression-related genes was inhibited. …”
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Activation of the JNK/SAPK and P38 Mitogen-Activated Protein Kinase Signaling Pathways Sensitize Tumor Cells to Cisplatin-Induced Apoptosis by Abdel Mansouri, Lon D. Ridgway, Qingxiu Zhang, Francois X. Claret

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Liraglutide Attenuates Hepatic Oxidative Stress, Inflammation, and Apoptosis in Streptozotocin-Induced Diabetic Mice by Modulating the Wnt/β-Catenin Signaling Pathway by Jie Yu, Yuan Zhao, Lingling Xu, Wei Li, Huabing Zhang, Fan Ping, Yuxiu Li

“…Furthermore, the expression of Wnt/β-catenin signaling pathway-associated molecules was upregulated in the liver of mice treated with liraglutide or insulin. …”
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HuR Plays a Positive Role to Strengthen the Signaling Pathways of CD4+ T Cell Activation and Th17 Cell Differentiation by Shiguang Yu, Morgan Tripod, Ulus Atasoy, Jing Chen

“…However, the role of RNA-binding protein HuR in the signaling pathways of their activation and differentiation has not been well characterized. …”
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Aloe-Emodin-Mediated Photodynamic Therapy Induces Apoptosis in Basal Cell Carcinoma Cells via Activation of ERK/JNK Signaling Pathway by Woodvine Otieno Odhiambo, Songmei Geng, Xiaopeng Wang, Xiaodong Chen, Mengting Qin, Meng Yuan, Yang Wang, Farooq Riaz, Chengcheng Liu, Yanhong Ji

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Cinnamaldehyde impacts key cellular signaling pathways for induction of programmed cell death in high-grade and low-grade human glioma cells by Yoo Na Kim, Ketki Patil, S. Balakrishna Pai

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The Anti-Inflammatory Effects of Shinbaro3 Is Mediated by Downregulation of the TLR4 Signalling Pathway in LPS-Stimulated RAW 264.7 Macrophages by Hwa-Jin Chung, Wonil Koh, Won Kyung Kim, Joon-Shik Shin, Jinho Lee, Sang Kook Lee, In-Hyuk Ha

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