Mitochondrial ATP-Sensitive K+ Channel Opening Increased the Airway Smooth Muscle Cell Proliferation by Activating the PI3K/AKT Signaling Pathway in a Rat Model of Asthma by Min Gao, Qinran Sun, Qingfa Liu

“…In conclusion, the mitoKATP channel opening increased the proliferation of ASMCs by activating the PI3K/AKT signaling pathway in a rat model of asthma.…”
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The role of mesenchymal cells in cholangiocarcinoma by Mireia Sueca-Comes, Elena Cristina Rusu, Jennifer C. Ashworth, Pamela Collier, Catherine Probert, Alison Ritchie, Marian Meakin, Nigel P. Mongan, Isioma U. Egbuniwe, Jesper Bøje Andersen, David O. Bates, Anna M. Grabowska

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Editorial: Infection-mediated inflammation that promotes cancer initiation and/or progression by Ibrahim M. Sayed, Ibrahim M. Sayed, Soumita Das

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An updated review summarizing the anticancer potential of flavonoids via targeting NF-kB pathway by Pratibha Pandey, Sorabh Lakhanpal, Danish Mahmood, Han Na Kang, Byunggyu Kim, Sojin Kang, Jinwon Choi, Min Choi, Shivam Pandey, Mahakshit Bhat, Shilpa Sharma, Fahad Khan, Moon Nyeo Park, Bonglee Kim, Bonglee Kim

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Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model by Tu Zhilan, Zhang Zengyu, Jin Pengpeng, Yang Hualan, Li Chao, Xi Yan, Guo Zimin, Hou Shuangxing, Li Weiwei

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Anticancer effects of 7,8-dihydromethysticin in human leukemia cells are mediated via cell-cycle dysregulation, inhibition of cell migration and invasion and targeting JAK/STAT pat... by Xiao Yi, Deng Taoran, Jiang Lijun, Wang Di

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Decreased expression of miR-200a and miR-223-3p in endometriosis during the secretory phase of menstrual cycle: Insights from a case-control study on molecular biomarkers and disea... by Yasaman Nazari Hagh, Mohamadreza Ahmadifard, Sedigheh Esmaelzadeh, Soheila Abbaszadeh, Naser Shokrzadeh

Subjects: “…Endometriosis, miRNA, Implantation, Signaling pathways, Biomarkers, Infertility, Menstrual cycle.…”
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Targeting Chondrocyte Hypertrophy as Strategies for the Treatment of Osteoarthritis by Da-Long Dong, Guang-Zhen Jin

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Phytochemicals in Breast Cancer Prevention and Treatment: A Comprehensive Review by Adil Farooq Wali, Jayachithra Ramakrishna Pillai, Sirajunisa Talath, Pooja Shivappa, Sathvik Belagodu Sridhar, Mohamed El-Tanani, Imran Rashid Rangraze, Omnia Ibrahim Mohamed, Nowar Nizar Al Ani

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Ginseng exhibits adaptogenic-like activity in mice exposed to hypoxic-anoxic stress through activation of antioxidant/BDNF protective mechanisms and inhibition of pro-inflammatory cytokines/NF-KB signaling pathways by James Olukayode Oni, Divine Oluwaferanmi Oyenekan, Yetunde Olamide Olayemi, Osarugue Christabel Irabor, Precious Ogbuji, McCarthy Oritseweyinmi Tova, Paul Ademola Adeleke, Gbemisayo Adetomiwa Abbas, Solomon Umukoro

“…The results of the study showed that ginseng demonstrated adaptogenic-like properties by attenuating neurobehavioral deficits in mice exposed to hypoxic-anoxic stress via multiple molecular mechanisms, relating to inhibition of corticosterone-mediated oxidative and inflammatory/apoptotic signaling pathways, and activation of GAD, BDNF and NFr-2 stress-protective defense systems. …”
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Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways by Binmei Zhang, Jingxiu Hou, Jiaren Liu, Junhui He, Yunan Gao, Guangnan Li, Tianjiao Ma, Xin Lv, Li Dong, Wei Yang

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Hydrogen decreases susceptibility to AngII-induced atrial fibrillation and atrial fibrosis via the NOX4/ROS/NLRP3 and TGF-β1/Smad2/3 signaling pathways. by Binmei Zhang, Jingxiu Hou, Jiaren Liu, Junhui He, Yunan Gao, Guangnan Li, Tianjiao Ma, Xin Lv, Li Dong, Wei Yang

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Effect of Tiaoxin Recipe on Memory Learning and Synaptic Plasticity in APP/PS1 Double Transgenic Alzheimer's Disease Mice based on αCaMKⅡ-CREB-BDNF Signal Pathway by Xiaowen WANG, Hong QIAN, Chunjuan SHEN, Yanjun LI, Haixin YUAN, Jian WANG

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Trillin inhibits MAP3K11/NF-κB/COX-2 signaling pathways through upregulation of miR-145-5p in castration-resistant prostate cancer by Yanlong Wang, Yulin Peng, Wenjun Hao, Chengjian He, Xiang Gao, Peng Liang, Haolin Zhao, Ying Wang, Liang Wang, Zhenlong Yu, Zhiyu Liu

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Astaxanthin relieves HT22 cells from LPS-induced inflammation and apoptosis by inhibiting oxygen species and regulating the TLR4/MyD88/NFκB signaling pathway by Tan Wang, Rongrong Li, Ping Niu, Zhen Wei, Donge Xie, Huorong Huang, Jiayao Pan, Chunshu Rong

“…In summary, we demonstrated that ATX can alleviate LPS-induced ROS accumulation, inflammation, and apoptosis, with its anti-inflammatory effects closely linked to the TLR4/MyD88/NFκB signaling pathway.…”
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Protective effects of seed oil from Nicotiana tabacum L. On D-galactose induced liver and brain damages of mice by regulating PI3K/Akt/Nrf2 signaling pathway by Ji Gu, Yongchao Wang, Shanshan Xiao, Yunye Zheng, Zhengxuan Wang, Yaping Liu, Limeng Zhang, Guiguang Cheng

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Regulation of reactive oxygen species and the role of mitochondrial apoptotic-related genes in rheumatoid arthritis by Conghui Gao, Chengqiang Zhang, Lixing Wen, Gailian Zhang, Xiaoping Liu, Jie Wang, Luping Cui, Rui Li, Tingting Nie, Jiaoniu Duan, Yingying Guo

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Mechanism of action of Xipayimaizibizi oral liquid on outlet obstruction-induced overactive bladder: An integrated study by Menglu Wang, Yang Yang, Yuhang Du, Jiamei Xie, Yige Zhao, Yongcheng An, Ziyi Shan, Shenyujun Wang, Meng Hao, Baosheng Zhao

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Serum Exosomes miR-122-5P Induces Hepatic and Renal Injury in Septic Rats by Regulating TAK1/SIRT1 Pathway by Wang J, Jiang Y, Yuan Y, Ma X, Li T, Lv Y, Zhang J, Chen L, Zhou J, Meng Y, Zhang B, Dong X, Ma L

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Transcriptome analysis unveils the mechanisms of oxidative stress, immunotoxicity and neurotoxicity induced by benzotriazole UV stabilizer-328 in zebrafish embryos by Xinlu Yang, Yijing Gan, Menghuan Zhang, Shaolin Xie, Mingfu Lin, Lixiang Zhong, Mengke Song, Jun Wang, Yumei Huang

Subjects: “…RIG-I-like receptor signaling pathway…”
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