How Hippo Signaling Pathway Modulates Cardiovascular Development and Diseases by Wenyi Zhou, Mingyi Zhao

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Sensitivity of signaling pathway dynamics to plasmid transfection and its consequences by Jaroslaw Smieja, Marzena Dolbniak

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Purinergic Signaling Pathway in Human Olfactory Neuronal Precursor Cells by Héctor Solís-Chagoyán, Edgar Flores-Soto, Marcela Valdés-Tovar, Montserrat G. Cercós, Eduardo Calixto, Luis M. Montaño, Carlos Barajas-López, Bettina Sommer, Arnoldo Aquino-Gálvez, Citlali Trueta, Gloria A. Benítez-King

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Diet restriction and exercise alleviate cognitive reduction of high fat diet (HFD)-induced obese mice by rescuing inflammation-mediated compromised insulin signaling pathway through activating AMPK/SIRT1 signal pathway and suppressing TLR4 signal pathway by Hu Zhang, Ye Zhang, Jiling Liang, Jiahang Li, Miao He, Xin Liu, Jielun Huang, Minghui Wang, Jingjing Fan, Ning Chen

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Shared signaling pathways and comprehensive therapeutic approaches among diabetes complications by Moein Ebrahimi, Hamid Ahmadieh, Mozhgan Rezaei Kanavi, Sare Safi, Saeed Alipour-Parsa, Soroor Advani, Christine M. Sorenson, Nader Sheibani

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Key Signaling Pathways Regulate the Development and Survival of Auditory Hair Cells by Yao Liu, Mei Wei, Xiang Mao, Taisheng Chen, Peng Lin, Wei Wang

“…In this review, we described and summarized the signaling pathways that regulate the development and survival of auditory HCs in SNHL. …”
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Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune Diseases by Juan Shi, Shuhong Chi, Jing Xue, Jiali Yang, Feng Li, Xiaoming Liu

“…The Wnt signaling pathway plays a key role in many biological aspects, such as cellular proliferation, tissue regeneration, embryonic development, and other systemic effects. …”
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Effect of Massage on the TLR4 Signalling Pathway in Rats with Neuropathic Pain by Qian Wang, Jing Lin, Peng Yang, Yingye Liang, Dongming Lu, Kailong Wang, Wei Gan, Jianping Fu, Zhenbao Gan, Mingchen Ma, Pingting Wu, Fengshi He, Jun Pang, Hongliang Tang

“…This study set out to investigate the effect of massage on the Toll-like receptor 4 (TLR4) signalling pathway in the dorsal root ganglia of rats that had undergone spinal nerve ligation (SNL), with the hypothesis that massage could be used as an analgesic. …”
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The Emerging Role of Rab5 in Membrane Receptor Trafficking and Signaling Pathways by Wanqiong Yuan, Chunli Song

“…In this review, we summarize the role of small Rab GTPases Rab5 in membrane receptor trafficking and the activation of signaling pathways, such as Ras/MAPK and PI3K/Akt, which ultimately affect cell growth, apoptosis, tumorigenesis, and tumor development. …”
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PMA Induces Vaccine Adjuvant Activity by the Modulation of TLR Signaling Pathway by Dool-Ri Oh, Hu Won Kang, Jong-Ro Kim, Sunoh Kim, In-Kyu Park, Joon Haeng Rhee, Won Keun Oh, Young Ran Kim

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On Fitting Of Mathematical Models Of Cell Signaling Pathways Using Adjoint Systems by Krzysztof Fujarewicz, Marek Kimmel, Andrzej Swierniak

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The Inhibitory Effects of Alpha 1 Antitrypsin on Endosomal TLR Signaling Pathways by Ahmed S. Elshikha, Georges Abboud, Rigena Avdiaj, Laurence Morel, Sihong Song

“…These data demonstrated that hAAT inhibited TLR7/8 and TLR9 signaling pathways, which are critical for lupus development. …”
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Expression of the JAK/STAT Signaling Pathway in Bullous Pemphigoid and Dermatitis Herpetiformis by K. Juczynska, A. Wozniacka, E. Waszczykowska, M. Danilewicz, M. Wagrowska-Danilewicz, J. Wieczfinska, R. Pawliczak, A. Zebrowska

“…A family of eleven proteins comprises the Janus kinases (JAK) and signal transducers and activators of transcription (STAT) signaling pathway, which enables transduction of signal from cytokine receptor to the nucleus and activation of transcription of target genes. …”
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Signalling pathways involved in urotensin II induced ventricular myocyte hypertrophy by Hadeel S. Al Ali, Glenn C. Rodrigo, David G. Lambert

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Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway by Ling-juan Liu, Li-qun Liu, Tao Bo, Shi-jun Li, Zhen Zhu, Rong-rong Cui, Ding-an Mao

“…Moreover, puerarin activated ERK signaling pathways in hOBs, and the antiapoptotic effect induced by puerarin was abolished by incubation of ERK inhibitor PD98059. …”
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Editorial: Signaling pathways and brain circuitry underlying circadian rhythms and sleep by Sydney Aten, Mino D. C. Belle, Cecilia G. Diniz Behn, Cecilia G. Diniz Behn

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Role of BMP-4 and Its Signaling Pathways in Cultured Human Melanocytes by Hee-Young Park, Christina Wu, Mina Yaar, Christina M. Stachur, Marita Kosmadaki, Barbara A. Gilchrest

“…These results demonstrate that BMP-4 activates MAPK/ERK signaling pathway to transiently activate MITF; however, chronic treatment of BMP-4 to melanocytes causes a down-regulation of the expression of MITF, possibly in a cAMP-dependent pathway.…”
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Canonical Wnt Signaling Pathway on Polarity Formation of Utricle Hair Cells by Di Deng, Xiaoqing Qian, Binjun Chen, Xiaoyu Yang, Yanmei Wang, Fanglu Chi, Yibo Huang, Yu Zhao, Dongdong Ren

“…Increasing evidence has indicated that the noncanonical Wnt/PCP signaling pathway plays a significant role in the development of the polarity of the inner ear. …”
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Phosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition by Christina Alves Peixoto, Ana Karolina Santana Nunes, Ana Garcia-Osta

“…The aim of this paper was to review present knowledge of the signaling pathways that underlie the use of PDE5-Is in neuroinflammation, neurogenesis, learning, and memory.…”
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Role of PPARs in Progression of Anxiety: Literature Analysis and Signaling Pathways Reconstruction by Olga I. Rudko, Artemii V. Tretiakov, Elena A. Naumova, Eugene A. Klimov

“…We used the Pathway Studio software (Elsevier). Signal pathways were created according to previously developed algorithms. …”
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