Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica) by Takuhiro Uto, De-Xing Hou, Osamu Morinaga, Yukihiro Shoyama

“…Moreover, molecular analysis demonstrated that 6-MSITC blocks the expressions of these factors by suppressing multiple signal transduction pathways to attenuate the activation of transcriptional factors. …”
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Molecular techniques for cancer diagnostics by Vimal Kishor Singh, Ramesh Chandra

“…Recent research reported vast genetic and epigenetic heterogeneity, differences in the gene-expression profiles, and signal transduction networks in a broad range of cancers. …”
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Correlation between SMADs and Colorectal Cancer Expression, Prognosis, and Immune Infiltrates by Ning Ding, Hongbiao Luo, Tao Zhang, Tianshu Peng, Yanru Yao, Yongheng He

“…Small mothers against decapentaplegic (SMAD) superfamily are intracellular signal transduction proteins associated with the development and prognosis of a variety of tumors. …”
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Discovery of MicroRNAs and Their Target Genes Related to Drought in Paulownia “Yuza 1” by High-Throughput Sequencing by Minjie Deng, Yabing Cao, Zhenli Zhao, Lu Yang, Yanfang Zhang, Yanpeng Dong, Guoqiang Fan

“…According to the functional classification of the target genes, Paulownia “yuza 1” may respond to drought stress via plant hormone signal transduction, photosynthesis, and osmotic adjustment. …”
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The Effects of Astaxanthin on Metabolic Syndrome: A Comprehensive Review by Chunhao Gao, Nengyun Gong, Fangtian Chen, Shiran Hu, Qingxin Zhou, Xiang Gao

“…These mechanisms primarily involve regulating signal transduction, transport, or metabolic pathways within the body, as well as influencing intestinal microbiota and metabolites, thereby exerting positive effects on metabolism and inhibiting the occurrence of MS. …”
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Genome-Wide Analysis and Expression Profiling of Watermelon <i>VQ</i> Motif-Containing Genes Under Abiotic and Biotic Stresses by Yanjun He, Jia Shen, Xinyang Xu, Weisong Shou

“…Valine-glutamine (VQ) motif-containing proteins play important roles in diverse plant developmental processes and signal transduction in response to biotic and abiotic stresses. …”
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Transcriptional regulation of suberin and its response to the environment by ZHOU Yue, AN Yongping, MA Rong, WANG Pei

“…Environmental factors also regulate the biosynthesis and deposition of suberin through complex signal transduction pathways. [Prospect] Future research should focus on the key regulatory nodes of suberin biosynthesis, particularly exploring the factors that influence species-specific deposition of suberin in crops. …”
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Pathogenic Process-Associated Transcriptome Analysis of Stemphylium lycopersici from Tomato by Dezhen Zhang, Wenjuan Chi, Cuicui Wang, Huijie Dai, Jintang Li, Chunlei Li, Fajun Li

“…The abilities to adhere and colonize a host surface, effectively damage host cell walls, regulate signal transduction to manage infection, and survive in a hostile plant environment are proposed as important factors for the pathogenesis of S. lycopersici in tomato. …”
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De Novo Transcriptome Sequencing of Olea europaea L. to Identify Genes Involved in the Development of the Pollen Tube by Domenico Iaria, Adriana Chiappetta, Innocenzo Muzzalupo

“…Moreover, different genes involved in signal transduction, transcription, and growth are overrepresented. …”
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Revisiting the role of IL-27 in obesity-related metabolic diseases: safeguard or perturbation? by Jinyang An, Donghua Fu, Ximei Chen, Conghui Guan, Conghui Guan, Lingling Li, Jia Bai, Haihong Lv, Haihong Lv

“…This article provides a comprehensive review of the latest findings on IL-27 expression and signal transduction in the regulation of immune inflammatory cells, as well as its implications in obesity and other related metabolic diseases. …”
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Recent advances in the structure and immunomodulatory activity of food-derived glycoprotein complex by Yu Zhong, Jiangxiong Zhu, Bifen Zhu, Hao Yin, Danfeng Wang, Yun Deng, Minyan Zhang, Chunrong Zhang

“…Glycoprotein complex can affect the expression of immune-related proteins and factors by activating cell surface receptors, regulating intracellular immune signal transduction, and ultimately play an immunomodulatory role in the body. …”
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Folic Acid Is Able to Polarize the Inflammatory Response in LPS Activated Microglia by Regulating Multiple Signaling Pathways by Antonia Cianciulli, Rosaria Salvatore, Chiara Porro, Teresa Trotta, Maria Antonietta Panaro

“…We investigated the ability of folic acid to modulate the inflammatory responses of LPS activated BV-2 microglia cells and the signal transduction pathways involved. To this aim, the BV-2 cell line was exposed to LPS as a proinflammatory response inducer, in presence or absence of various concentrations of folic acid. …”
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Dual AAV/IL-10 Plus STAT3 Anti-Inflammatory Gene Delivery Lowers Atherosclerosis in LDLR KO Mice, but without Increased Benefit by Maohua Cao, Junaid A. Khan, Bum-Yong Kang, Jawahar L. Mehta, Paul L. Hermonat

“…Both IL-10 and STAT3 are in the same signal transduction pathway, with IL-10-bound IL10 receptor (R) acting through STAT3 for anti-inflammatory effect. …”
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Bioinformatics Method Was Used to Analyze the Highly Expressed Gene FAM83A of Breast Cancer in Young Women by Yongzhe Tang, Hao Wang, Qi He, Yuanyuan Chen, Jie Wang

“…The active site of PLDc and the functional domain of DUF1669 can be involved in signal transduction and gene expression regulation in tumorigenesis and metastasis. …”
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Hydrogen Peroxide Is Involved in Salicylic Acid-Elicited Rosmarinic Acid Production in Salvia miltiorrhiza Cell Cultures by Wenfang Hao, Hongbo Guo, Jingyi Zhang, Gege Hu, Yaqin Yao, Juane Dong

“…These results indicated that H2O2 is secondary messenger for signal transduction, which can be induced by SA, significantly and promotes RA accumulation.…”
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Genome-Wide Identification of the ABC Gene Family in Rosaceae and Its Evolution and Expression in Response to Valsa Canker by Chenglong Du, Hongqiang Yu, Huanhuan Hu, Zhiqi Dou, Cunwu Zuo, Junqiang Niu

“…Gene ontology (GO) enrichment analysis indicated the involvement of ABC proteins in transmembrane transport and signal transduction pathways. Under <i>Valsa pyri</i> infection, most ABC genes were upregulated in the early stages, highlighting the role of ABCG genes in pathogen response. …”
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Transcriptome Analysis Reveals Complex Defensive Mechanisms in Salt-Tolerant and Salt-Sensitive Shrub Willow Genotypes under Salinity Stress by Dezong Sui, Baosong Wang

“…Compared to JW9-6, JW2372 contained more DEGs involved in the maintenance of the cell wall integrity, ABA, and ethylene signal transduction pathways. In addition, more DEGs encoding heat shock proteins were found in JW2372. …”
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Differential Evolutionary Constraints in the Evolution of Chemoreceptors: A Murine and Human Case Study by Ricardo D’Oliveira Albanus, Rodrigo Juliani Siqueira Dalmolin, José Luiz Rybarczyk-Filho, Mauro Antônio Alves Castro, José Cláudio Fonseca Moreira

“…We have observed significant differences regarding the constraints on the orthologous groups and network topologies of chemoreceptors and signal transduction machinery. Our findings suggest that chemosensory receptor genes are less constrained than their signal transducing machinery, resulting in greater receptor diversity and conservation of information processing pathways. …”
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Swimming Exercise Alleviated Insulin Resistance by Regulating Tripartite Motif Family Protein 72 Expression and AKT Signal Pathway in Sprague-Dawley Rats Fed with High-Fat Diet by Jie Qi, Bo Yang, Cailing Ren, Jian Fu, Jun Zhang

“…These results suggest that an 8-week swimming exercise improves HFD-induced insulin resistance maybe through a reduction of TRIM72 in skeletal muscle and enhancement of AKT signal transduction.…”
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Constitutional Nephrin Deficiency in Conditionally Immortalized Human Podocytes Induced Epithelial-Mesenchymal Transition, Supported by β-Catenin/NF-kappa B Activation: A Consequen... by Gian Marco Ghiggeri, Maddalena Gigante, Armando Di Donato

“…The analysis of the main intracellular signal transduction pathways evidenced some major anomalies consequent with the nephrin abrogation. …”
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