Functional Characterization of the SHIP1-Domains Regarding Their Contribution to Inositol 5-Phosphatase Activity by Spike Murphy Müller, Nina Nelson, Manfred Jücker

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Sex differences of molecular mechanisms of insulin sensitivity in young and adult C57BL/6J mice by T. V. Yakovleva, A. Yu. Kazantseva, E. N.  Makarova, N. M. Bazhan

“…The aim of this work was to investigate the insulin signal transduction gene expression in mice of different sex and age. …”
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Receptor for Advanced Glycation End Products and Its Involvement in Inflammatory Diseases by Yaw Kuang Chuah, Rusliza Basir, Herni Talib, Tung Hing Tie, Norshariza Nordin

“…These effects endow RAGE with the role in the signal transduction from pathogen substrates to cell activation during the onset and perpetuation of inflammation. …”
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Spatio-temporal models of synthetic genetic oscillators by Cicely K. Macnamara, Mark A. J. Chaplain

“…Signal transduction pathways play a major role in many important aspects of cellular function e.g. cell division, apoptosis. …”
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Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover. by Shoujun Huang, Zhao Zhang, Chunxia Zhang, Xiangdong Lv, Xiudeng Zheng, Zhenping Chen, Liwei Sun, Hailong Wang, Yuanxiang Zhu, Jing Zhang, Shuyan Yang, Yi Lu, Qinmiao Sun, Yi Tao, Feng Liu, Yun Zhao, Dahua Chen

“…Although activation of Smoothened and its downstream signal transduction have been intensively studied, less is known about how Patched receptor is regulated, and particularly how this regulation contributes to appropriate Hedgehog signal transduction. …”
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Synthetic transmembrane DNA receptors enable engineered sensing and actuation by Ze-Rui Zhou, Man-Sha Wu, Zhenglin Yang, Yuting Wu, Weijie Guo, Da-Wei Li, Ruo-Can Qian, Yi Lu

“…Abstract In living organisms, cells synergistically couple cascade reaction pathways to achieve inter- and intracellular signal transduction by transmembrane protein receptors. …”
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The Effect of Endotoxin-Induced Inflammation on the Activity of the Somatotropic Axis in Sheep by Maciej Wójcik, Dorota Anna Zieba, Joanna Bochenek, Agata Krawczyńska, Marcin Barszcz, Alina Gajewska, Hanna Antushevich, Andrzej Przemysław Herman

“…The further goal was to determine the effect of inflammatory factors on individual components involved in intracellular signal transduction to GH via the GH receptor (GHR). The research was carried out on 24 seasonal sheep kept under a short-day photoperiod, randomly divided into two groups. …”
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Interaction of Herbal Compounds with Biological Targets: A Case Study with Berberine by Xiao-Wu Chen, Yuan Ming Di, Jian Zhang, Zhi-Wei Zhou, Chun Guang Li, Shu-Feng Zhou

“…Based on the biological process classification of in vitro berberine targets, those targets related to signal transduction, intracellular signalling cascade, cell surface receptor-linked signal transduction, cell motion, cell cycle control, immunity system process, and protein metabolic process are most frequently involved. …”
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IL-6-mediated MHC class II induction on RIN-5AH insulinoma cells by IFN-γ occurs via the G-protein pathway by S. Vassiliadis, G. K. Papadopoulos

“…At the same time we noted a 5-fold increase of these histocompatibility antigens by IL-6. Signal transduction analysis reveals that IL-6-induced MHC class II expression is specifically mediated by the G-protein system (activation of p21ras by IL-6) since mevalonic acid lactone (a Gprotein inhibitor) abolishes the action of IL-6. …”
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miR-126 and miR-126*: New Players in Cancer by Jeannette Meister, Mirko H. H. Schmidt

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Resistance Response of the Jasmonic Acid and Salicylic Acid Signaling Pathways in Mango Fruits Infected with Lasodiplodia theobromae by QU Xiangxiang, HU Meijiao, SUN Jinhua, GONG Deqiang, GAO Zhaoyin, CHEN Gengxin, LI Min

“…Overall, these results indicate that infection with L. theobromae activates the synthesis of JA and its signal transduction, but inhibits the synthesis and signal transduction of SA in mango fruits.…”
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Activity of Various Cathepsin Proteases and Enrichment of Klotho Protein in the Urine and Urinary Extracellular Vesicles After SARS-CoV-2 Infection by Niharika Bala, Ramish H. Rafay, Sarah C. Glover, Abdel A. Alli

“…Pathway analyses of the proteomics data showed most of the identified proteins were involved in signal transduction, stress response, protein metabolism, and transport. …”
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Effects of IGF-1 on IK and IK1 Channels via PI3K/Akt Signaling in Neonatal Cardiac Myocytes by Richard M. Millis, Zikiar V. Alvin, Aiqiu Zhao, Georges E. Haddad

“…These findings demonstrate that IGF-1 may contribute to cardiac hypertrophy by PI3K/Akt signal transduction mechanisms in neonatal rat cardiomyocytes. …”
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Fungal photobiology: a synopsis by L.M. Corrochano

“…The photobiology of fungi has been extensively investigated, but in recent years the identification of the first fungal photoreceptor, WC-1 in the ascomycete Neurospora erassa, and the discovery that similar photoreceptors are required for photoreception in other ascomycete, basidiomycete and zygomycete fungi has allowed the molecular characterization of light reception and the early steps of signal transduction in a number of model fungi. This contribution is based on presentations made at the Special Interest Group Meeting on "Fungal Photobiology" held during IMC9. …”
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Investigation of intracellular signals generated by γ-interferon and IL-4 leading to the induction of class II antigen expression by S. Vassiliadis, N. Kyrpides, D. Stravopodis, M. Grigoriou, I. Athanassakis, J. Papamatheakis

“…Signal transduction plays a vital role in cellular behaviour as cells respond to various stimuli in different ways and utilize diverse pathways for accomplishing their task. …”
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Physiological and transcriptomic analysis of the effect of overexpression of the NTPIP2;4 gene on drought tolerance in tobacco by Xu Luo, Yuanshuai Shi, Jie Tan, Tao Long, Juntao Song, Yang Liu

“…The DEGs were enriched mainly in the plant MAPK signaling pathway, the plant hormone signal transduction pathway, amino sugar and nucleotide sugar metabolism, starch and sucrose metabolism and plant-pathogen interaction pathways. …”
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Analysis of significantly associated regions and candidate genes for dwarf stem trait in Brassica napus based on BSA-sequencing by ZHAO Weiguo, TA Na, WANG Hao, YANG Zelin

“…Five candidate genes within the significantly associated regions were identified and involved in the regulation of plant auxin synthesis and gibberellin signal transduction.…”
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MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway by Zigui Chen, Chao Liu, Wei Zheng, Zhilong Li, Yuanhui Tang, Jun Peng, Changfeng Miao, Dandan Zheng, Ying Xia

“…The occurrence of EMT involves many signal transduction pathways and complex molecular mechanisms related to calnexin, growth factors, transcription factors, and the microenvironment. …”
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Multi-omic analysis on the molecular mechanisms of rapid growth in ‘Deqin’ alfalfa after space mutagenesis by Qian Kuang, Chenggang He, Heping Huang, Hua Jiang

“…By integrating multi-omics data, we elucidated the synergistic effects of pathways such as hormone signal transduction and tryptophan metabolism on the rapid growth of the mutants. …”
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