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Comparison of sialic acid content in bovine and buffalo milk and meat
Published 2023-11-01“… Animal-origin food, such as meat and milk, are important sources of sialic acids (SIAs) with relevant implications for human health. …”
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New insights into the immunomodulatory potential of sialic acid on monocyte-derived dendritic cells
Published 2024-11-01Subjects: Get full text
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Estimation of Sialic Acid and IL10 Levels in Stage 1 and 2 Periodontitis Patients
Published 2019-01-01“…This study aimed at evaluating and comparing the role of sialic acid and IL10 in the early and moderate stages of periodontitis. …”
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Salivary Lipid Peroxidation and Total Sialic Acid Levels in Smokers and Smokeless Tobacco Users as Maraş Powder
Published 2012-01-01“…We aimed to investigate the effects of MP on salivary total sialic acid (TSA) and malondialdehyde (MDA) levels and to compare these parameters in smokers and MP users (MPUs). …”
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Changes in glycosphingolipid levels in plasma and cerebrospinal fluid of individuals with Lysosomal Free Sialic Acid Storage Disorder
Published 2025-01-01“…Lysosomal free sialic acid storage disorder (FSASD) is a rare, multisystem disease caused by biallelic pathogenic variants in SLC17A5, encoding the lysosomal transmembrane sialic acid exporter, sialin. …”
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Integrated SegFlow, µSIA, and UPLC for Online Sialic Acid Quantitation of Glycoproteins Directly from Bioreactors
Published 2025-01-01“…To achieve consistent levels of sialic acid‐to‐protein ratio, the time of upstream harvest and conductivity of downstream wash buffers must be tightly regulated based on the sialic acid content. …”
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The Role of Sialic Acid-Binding Receptors (Siglecs) in the Immunomodulatory Effects of Trypanosoma cruzi Sialoglycoproteins on the Protective Immunity of the Host
Published 2013-01-01“…In Trypanosoma cruzi infection, the parasite-derived mucins are the main acceptors of sialic acid and it has been suggested that they play a role in various host-parasite interactions during the course of Chagas disease. …”
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Relevance of superoxide dismutase type 1 to lipoid pneumonia: the first retrospective case-control study
Published 2025-01-01Subjects: Get full text
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Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter
Published 2025-02-01Subjects: Get full text
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N-acetylated sugars in clownfish and damselfish skin mucus as messengers involved in chemical recognition by anemone host
Published 2025-01-01“…We found significantly higher levels of sialic acid and its precursor in the non-symbiotic damselfishes. …”
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Neu5Ac Induces Human Dental Pulp Stem Cell Osteo-/Odontoblastic Differentiation by Enhancing MAPK/ERK Pathway Activation
Published 2021-01-01“…Results. The existence of sialic acid on the DPSC membrane was confirmed by fluorescent microscopy, and the ability of osteo-/odontoblastic differentiation was decreased after removing sialic acid by neuraminidase. …”
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SLC35A2 gene product modulates paramyxovirus fusion events during infection.
Published 2025-01-01“…Using a recombinant SeV expressing destabilized eGFP (rSeVCdseGFP) in a loss-of-function CRISPR screen, we identified the CMP-sialic acid transporter (CST) gene SLC35A1 and the UDP-galactose transporter (UGT) gene SLC35A2 as essential for paramyxovirus infection. …”
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SIAE Rare Variants in Juvenile Idiopathic Arthritis and Primary Antibody Deficiencies
Published 2017-01-01“…Sialic acid acetylesterase (SIAE) deficiency was suggested to lower the levels of ligands for sialic acid-binding immunoglobulin-like receptors, decreasing the threshold for B-cell activation. …”
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CD22 modulation alleviates amyloid β-induced neuroinflammation
Published 2025-02-01“…Moreover, sCD22 activated microglia via sialic acid binding domain and 2,6 linked sialic acid glycan on sCD22. …”
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Effect of Maternal Administration of Edible Bird’s Nest on the Learning and Memory Abilities of Suckling Offspring in Mice
Published 2018-01-01“…It has been reported that sialic acid from edible bird’s nest (EBN) can facilitate the development of brain and intelligence. …”
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The Roles of Siglec7 and Siglec9 on Natural Killer Cells in Virus Infection and Tumour Progression
Published 2020-01-01“…The function of natural killer (NK) cells, defending against virus infection and tumour progression, is regulated by multiple activating and inhibiting receptors expressed on NK cells, among which sialic acid-bind immunoglobulin-like lectins (Siglecs) act as a vital inhibitory group. …”
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Potential of Peptides as Inhibitors and Mimotopes: Selection of Carbohydrate-Mimetic Peptides from Phage Display Libraries
Published 2012-01-01“…Several anti-influenza drugs such as oseltamivir and zanamivir are derivatives of sialic acid, which inhibits neuraminidase. However, it is very difficult to prepare a diverse range of sugar derivatives by chemical synthesis or by the isolation of natural products. …”
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Nonhematopoietic Variants of Erythropoietin in Ischemic Stroke: Need for Step-Wise Proof-of-Concept Studies
Published 2010-01-01“…Characterized by its low sialic acid content and therefore exhibiting a very short plasma half-life, Neuro-EPO can probably not be administered systemically via the blood. …”
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