Predictive factors of thrombosis during autologous stem cell transplantation in multiple myeloma: Experience from EHU Oran (Algeria) by Mohammed Amine BEKADJA, Brahim BENZINEB, Mansour BELKACEM, Hafida OUDJERIOUAT, Badra ENTASOLTAN, Soufi OSMANI, Kamila AMANI, Samira BOUCHAMA, Leila CHAREF, Mohamed BRAHIMI, Abdessamad ARABI, Rachir Amar BOUHASS, Nabil YAFOUR

“…Results-Among 411 patients with MM underwent autologous transplantation of which 249 were male with a sex ratio of 1,53. The overall incidence of thrombosis was estimated at 18,49% (76 patients). …”
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Risk factors associated with degenerative glenohumeral osteoarthritis by Ravi Prakash, Nitin B Jain, Ziyi Chen, Folefac D Atem, Michael S Khazzam, Rashmi Pathak, Daniel Tai, Ursa BezanPetric, Estefanie Garduno Rapp

“…Univariate, least absolute shrinkage and selection operator and multivariate analyses identified risk factors, including age, body mass index (BMI), sex, work-related shoulder problems, shoulder disability, dislocation, previous trauma, surgery, smoking, hypertension, diabetes, depression, heart disease, OA, night pain and overall sleep quality.Results A total of 1827 cases and 1556 controls were identified for GH OA. …”
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Associations of early life per- and polyfluoroalkyl substances (PFAS) exposure with body mass index and risk of overweight or obesity at age 2–18 years: Mixture analysis in the pro... by Zeyu Li, Guoying Wang, Joseph M. Braun, Xiumei Hong, Giehae Choi, Shawn P. O’Leary, Chang Ho Yu, Colleen Pearson, William G. Adams, Zhihua (Tina) Fan, Jessie P. Buckley, Xiaobin Wang

“…We explored the effect modification by maternal pre-pregnancy OWO, child age, sex, and race. Results: Maternal plasma samples had PFAS detection frequencies from 87 % to 100 % and geometric means ranging from 0.11 to 3.67 ng/mL. …”
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Association of Fontan Pathophysiology With Plasma Bile Acids by Ashish H. Shah, MD, MD-Research, Arun Surendran, MSc, Pedram Hassan-Tash, BSc, MD, C. Nolan Turnbull, BSc, Nicole Johnston, MSc, David Goodlett, BSc, PhD, Jun Han, PhD, Robin A. Ducas, MD, James W. Tam, MD, Eberhard Renner, MD, Todd A. Duhamel, PhD, Michel Aliani, MSc, PhD, Amir Ravandi, MD, PhD, Richard A. Krasuski, MD

“…Methods: Patients with Fontan circulation were compared to age- and sex-matched healthy controls with regard to body composition, markers of frailty, cardiopulmonary exercise testing, and resting and exercise-augmented hemodynamics. …”
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The Relationship between Simple Snoring and Metabolic Syndrome: A Cross-Sectional Study by Juanjuan Zou, Fan Song, Huajun Xu, Yiqun Fu, Yunyan Xia, Yingjun Qian, Jianyin Zou, Suru Liu, Fang Fang, Lili Meng, Hongliang Yi, Jian Guan, Huaming Zhu, Bin Chen, Shankai Yin

“…The polynomial linear trend test was used to assess the linear trend across snoring intensity for metabolic score, and logistic regression was used to evaluate the odds ratios (ORs) for MetS after controlling for age, sex, obesity, smoking status, and alcohol consumption. …”
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Biological embodiment of educational attainment and future risk of breast cancer: findings from a French prospective cohort by Cyrille Delpierre, Raphaële Castagné, Eloïse Berger, Gianluca Severi, Marie-Christine Boutron-Ruault, Laura Baglietto, Laure Dossus, Amandine Gelot, Richard Dudouet

“…Specific biomarkers associated with the cardiovascular (systolic blood pressure (SBP), diastolic blood pressure (DBP), triglycerides (TG), high-density lipoprotein (HDL)), inflammatory (C reactive protein (CRP)) and hormonal systems (sex hormone-binding globulin (SHBG) and oestradiol) were found socially distributed (OR CRP-high=0.70 (95% CI 0.54; 0.91), OR TG-high=0.79 (95% CI 0.61; 1.04), OR DBP-high=0.69 (95% CI 0.53; 0.90), OR SBP-high=0.57 (95% CI 0.44; 0.74), OR HDL-high=0.79 (95% CI 0.60; 1.03), (OR SHBG-high=0.67 (95% CI 0.52; 0.88), OR oestradiol-high=1.34 (95% CI 1.00; 1.79); model 1). …”
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Development and Validation of a Risk Prediction Model for Ventricular Arrhythmia in Elderly Patients with Coronary Heart Disease by Ying Dong, Yajun Shi, Jinli Wang, Qing Dan, Ling Gao, Chenghui Zhao, Yang Mu, Miao Liu, Chengliang Yin, Rilige Wu, Yuqi Liu, Yang Li, Xueping Wang

“…In the multiparameter model, seven independent predictors were selected: LVEF, LAV, HLP, QTcd, sex, Tp-e/QT, and age. Increased HLP, Tp-e/QT, QTcd, age, and LAV were risk factors (RR > 1), while female and increased LVEF were protective factors (RR < 1). …”
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Topographical mapping of metabolic abnormalities in multiple sclerosis using rapid echo-less 3D-MR spectroscopic imaging at 7T by Eva Niess, Assunta Dal-Bianco, Bernhard Strasser, Fabian Niess, Lukas Hingerl, Beata Bachrata, Stanislav Motyka, Paulus Rommer, Siegfried Trattnig, Wolfgang Bogner

“…Materials and Methods: This study included 26 MS patients (13 women; median age 34) and 13 age- and sex-matched healthy controls (7 women; median age 33). …”
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SF1-specific deletion of the energy sensor AMPKγ2 induces obesity by Óscar Freire-Agulleiro, Ánxela Estévez-Salguero, Vitor Ferreira, Cassie Lynn Holleman, Julia García-Currás, Ismael González-García, Rubén Nogueiras, Manuel Tena-Sempere, Cristina García-Cáceres, Carlos Diéguez, Miguel López

“…Results: Our findings reveal that, in contrast to the obesity-protective effect of the genetic deletion of AMPKα subunits, the loss of AMPKγ2 in SF1 neurons leads to a sex-independent and feeding-independent obesity-prone phenotype due to decreased thermogenesis in brown adipose tissue (BAT) and reduced browning of WAT, resulting in lower energy expenditure. …”
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Baseline Serum Cholesterol Is Associated with a Response to Pegylated Interferon Alfa-2b and Ribavirin Therapy for Chronic Hepatitis C Genotype 2 by Naota Taura, Tatsuki Ichikawa, Hisamitsu Miyaaki, Yoshiko Kadokawa, Takuya Tsutsumi, Shotaro Tsuruta, Yuji Kato, Osami Inoue, Noboru Kinoshita, Kazuo Ohba, Hiroyuki Kato, Kazuyuki Ohata, Junichi Masuda, Keisuke Hamasaki, Hiroshi Yatsuhashi, Kazuhiko Nakao

“…The significance of age, sex, BMI, AST level, ALT level, WBC, hemoglobin, platelet count, gamma-glutamyltransferase, total cholesterol level (TC), LDL level, HCV RNA, and histological evaluation was examined for SVR using logistic regression analysis. …”
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Investigating mental health disparities in rural sexual and gender minority adults: protocol for the rural exploration and approaches to LGBTQ + Mental Health (REALM) prospective c... by Shoshanna L. Fine, Kalai Willis, Iaah L. Lucas, Kirsten F. Siebach, Jennifer L. Glick, Mariah Valentine-Graves, Savannah Winter, Michael Smith, Thomas Waltz, Gina Bailey Herring, Marissa Hannah, Holly C. Wilcox, Travis Sanchez, Stefan D. Baral, Sarah M. Murray

“…This will include: up to 1,000 cisgender sexual minority persons (up to n = 500 each cisgender women and cisgender men); and up to 1,500 gender minority persons (up to n = 500 persons who were assigned male at birth and identify as a woman, female, and/or transfeminine; up to n = 500 persons who were assigned female at birth and identify as a man, male, and/or transmasculine; and up to n = 500 persons who identify as some other gender, including non-binary, gender non-conforming, and/or agender regardless of sex assigned at birth). All enrolled participants will subsequently be followed over a 12-month period, with repeated surveys at three-month intervals. …”
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Symptoms of anxiety, depression, and post-traumatic stress disorder 6 weeks and 6 months after ICU: Six out of 10 survivors affected by E van der Merwe, L Stroud, G Sharp, N van Vuuren, M Mosola, T Fodo, F Paruk

“…Associations for significant psychological symptoms comprised female sex, younger age, a diagnosis of trauma and frightening memories of the ICU admission. …”
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Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes by Shuai Zhang, Ruixue Wang, Kun Luo, Shipeng Gu, Xinyu Liu, Junhan Wang, Ludan Zhang, Lin Sun

“…RNA m6A modification in Drosophila has proven to be involved in sex determination regulated by Sxl and may affect X chromosome expression through the MSL complex. …”
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Is lean mass quantity or quality the determinant of maximal fat oxidation capacity? The potential mediating role of cardiorespiratory fitness by Edgardo Opazo-Díaz, Juan Corral-Pérez, Alejandro Pérez-Bey, Alberto Marín-Galindo, Adrián Montes-de-Oca-García, María Rebollo-Ramos, Daniel Velázquez-Díaz, Cristina Casals, Jesús-Gustavo Ponce-González

“…A strength cluster was calculated with handgrip and long jump adjusted by sex and age. Data were analyzed using multiple linear regression and mediation analyses.Results Total lean-mass and leg lean-mass were not associated with MFO. …”
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Circulating Baseline CXCR3+Th2 and Th17 Cell Proportions Correlate With Trabecular Bone Loss After 48 Weeks of Biological Treatment in Early Rheumatoid Arthritis by Julia M. Scheffler, Christina Drevinge, Catharina Lindholm, Inger Gjertsson, Kristina Lend, Merete Lund Hetland, Mikkel Østergaard, Till Uhlig, Marte Schrumpf Heiberg, Espen A. Haavardsholm, Michael T. Nurmohamed, Jon Lampa, Tuulikki Sokka‐Isler, Dan Nordström, Kim Hørslev‐Petersen, Bjorn Gudbjornsson, Gerdur Gröndal, Ronald vanVollenhoven, Hans Carlsten, Mattias Lorentzon, Anna‐Karin Hultgård Ekwall, Anna Rudin, Ulrika Islander

“…The overall bone loss was not associated with age, body mass index, sex, intraarticular glucocorticoid injections, or baseline disease activity. …”
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N‐terminal pro brain natriuretic peptide reference values in community‐dwelling older adults by Ulrike Braisch, Wolfgang Koenig, Dietrich Rothenbacher, Michael Denkinger, Nele Friedrich, Stephan B. Felix, Till Ittermann, Marcus Dörr, Dhayana Dallmeier

“…Based on predictors a reference population of 441 subjects (ActiFE, n = 227; SHIP‐TREND‐0, n = 214) without history of diabetes, cardiovascular, or pulmonary diseases and with systolic blood pressure (BP) <140 mmHg, diastolic BP ≥60 and ≤90 mmHg, haemoglobin in men ≥14 and ≤18 g/dL and in women ≥12 and ≤16 g/dL, GFR ≥60 mL/min/1.73 m2, CRP <5 mg/L, BMI ≥18 and ≤33 kg/m2, and hs‐cTnI <40 ng/L were built with NT‐proBNP median levels and 97.5% quantiles reported stratified by sex and age. In a secondary analysis the URL among 97 SHIP‐TREND‐0 participants with a left ventricular ejection fraction (LVEF) ≥50 and no diastolic dysfunction were estimated. …”
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Estimation of the incidence of invasive meningococcal disease using a capture–recapture model based on two independent surveillance systems in Catalonia, Spain by Pilar Ciruela, Carmen Munoz-Almagro, Cristina Rius, Tomas Pumarola, Frederic Gomez-Bertomeu, Núria Soldevila, Ángela Domínguez, LAURA RUIZ, Ana Calderon, Ana Martinez, M Ángeles Domínguez, Mercé Garcia, Dionisia Fontanals, Gloria Carmona, Pere Godoy, Goretti Sauca, Jordi Vila, Marta Vilaró, Mireia Jané, Tomás Garcia, Sergi Hernández, Maria Teresa Bastida, Frederic Ballester, Isabel Pujol, Miguel Angel Benítez, Alba Cebollero, Jordi Bosch, Margarida Curriu, Fe Tubau Quintano, Jose Manuel Ramirez, Ma Jose Fusté, Carme Gallés, Pilar Hernandez Pérez, ElisendaCapdevila GildeBernabe, Paula Gassiot, Araceli González-Cuevas, Marius Juanpere, Amaresch Perez Arguello, Carmina Martí, Nuria Margall, Lurdes Matas, Montserrat Giménez, Montserrat Morta, Gloria Trujillo, Silvia Noguer, Montserrat Olsina, Amaia Oteiza Ubanell, Pepa Perez, Mar Olga Pérez-Moreno, Juanjo Gonzales, Xavier Raga, Mercè Ribelles, Esther Sanfeliu, Isabel Sanfeliu, Anna Vilamala, César Arias, Irene Barrabeig, Neus Camps, Mònica Carol, Núria Follia, Sofia Minguell, Ignasi Parron, Ma Rosa Sala-Farré, Ariadna Rovira

“…Multivariate vector generalised linear model was performed for adjusted estimation.Measures The variables collected were age, sex, year of report, size of municipality (&lt;10 000 and ≥10 000), clinical form, death, serogroup, country of birth and type of reporting centre (private and public).Results The sensitivity of the two combined surveillance systems was 88.5% (85.0–92.0). …”
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Associations of dietary choline intake and kidney function with hyperuricemia in Chinese children and adolescents: a cross-sectional studyResearch in context by Chengping Li, Jing Li, Zhiquan Diao, Lianhong Chen, Siwen Yu, Lianlong Yu, Qianrang Zhu, Xiaomei Dong, Yiya Liu, Tao Liu, Dan Liu

“…Based on recommendation in Clinical Paediatric Nephrology (3rd ed), HUA is defined based on fasting serum uric acid levels, with cutoffs varying by age and sex. The associations between choline intake and HUA were analysed using weighted logistic regression models, restricted cubic spline models, and linear regression models. …”
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Assessing Knowledge and Preventive Practices Regarding Infectious Diseases Among Healthcare Workers in Hail City, Saudi Arabia by Sandro Costanilla Villareal

“…Of note, the participants’ educational attainment (p < .000) and education on COVID-19 (p = .001) were found to have significant relationships with their knowledge. Accordingly, sex (p < .000), educational attainment (p < .000), occupation (p = .001), and education on COVID-19 (p < .000) were found to have significant relationships with employment of COVID-19 preventive measures. …”
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Correlation between Insulin Resistance and Thyroid Nodule in Type 2 Diabetes Mellitus by Yunzhao Tang, Tiantian Yan, Gang Wang, Yijun Chen, Yanjuan Zhu, Zhenhuan Jiang, Min Yang, Chenguang Li, Zhu Li, Ping Yu, Shanshan Wang, Nannan Zhu, Qiuyue Ren, Changlin Ni

“…Logistic regression analysis showed that age, sex, FT4, and HOMA-IR were positive factors for thyroid nodule. …”
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