Relationship between effective blood flow rate and clinical outcomes in maintenance hemodialysis patients: a single-center study by Zhoucang Zhang, Jiarui Li, Jiaxiang Ding, Shenglei Zhang, Mei Wang, Jinsheng Xu

“…After adjusting for relevant factors including age, sex, vintage, diabetes, CVD, receiving hemodiafiltration (HDF) treatment and spKt/V, Cox models indicated a low time-averaged eBFR (≤ 275 ml/min) was associated with increased risks of all-cause mortality (hazard ratio [HR] 14.18; 95% confidence interval [CI], 3.14–64.1) and new MACE (HR 3.76; 95% CI, 1.91–7.40) in MHD patients. …”
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Oakland score to identify low-risk patients with lower gastrointestinal bleeding performs well among emergency department patients by Daniel D. DiLena, Sean C. Bouvet, Madeline J. Somers, Maqdooda A. Merchant, Theodore R. Levin, Adina S. Rauchwerger, Dana R. Sax

“…Prediction variables include age, sex, previous LGIB admission, systolic blood pressure, heart rate, and hemoglobin concentration, and scores range from 0 to 35 points, with higher scores indicating greater risk. …”
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Factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies in paediatric age: a prospective multicentre cohort study by Giorgio Bedogni, Roberto Berni Canani, Laura Carucci, Rita Nocerino, Serena Coppola, Pasqualina Capasso, Veronica Giglio

“…Background We aimed at identifying the factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA), a group of common paediatric conditions including food protein–induced: enteropathy (FPE), allergic proctocolitis (FPIAP), enterocolitis syndrome (FPIES), and motility disorders (FPIMD).Methods Prospective multicentre cohort study involving paediatric patients (both sexes, aged ≤14 y) with non-IgE-GIFA diagnosed and followed for 24 months at a Tertiary Centre for Paediatric Allergy, Gastroenterology and Nutrition. …”
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Using CT imaging to identify sarcopenia as a risk factor for severe falls in older adults by Nadja Fries, Angeliki Kotti, Mischa Woisetschläger, Anna Spångeus

“…In the multivariate analysis, higher level of frailty, male sex as well as lower BMI, VAT and SAT remained as risk factors for low SMI ratio. …”
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Serum Antidiuretic Hormone Level in Nocturnal Enuretic School Children in a Tertiary Care Hospital in Bangladesh: A Cross‐Sectional Study by Jannatul Fardous, Anjuman Ara, Md. Iqbal Hossain, Asma Labony, Tanjila Afrin, Rezwana Ashraf, Reaz Uddin, Habiba Jesmin, Md. Kabir Alam, Mohammad Ashraful Amin, Anwar Hossain Khan, Zahid Hasan Khan

“…There was no significant association between sex and PMNE (p = 0.370). Children with PMNE exhibited significantly lower serum ADH levels compared to the comparison group (p < 0.05). …”
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Circulating Levels of Betatrophin and Irisin Are Not Associated with Pancreatic β-Cell Function in Previously Diagnosed Type 2 Diabetes Mellitus Patients by Lingshu Wang, Jun Song, Chuan Wang, Peng Lin, Kai Liang, Yu Sun, Tianyi He, Wenjuan Li, Ruxing Zhao, Jun Qin, Yiran Lu, Jinbo Liu, Fuqiang Liu, Xinguo Hou, Li Chen

“…The present study aims to demonstrate the associations of circulating betatrophin and irisin levels with β-cell function, assessed by the area under the curve (AUC) of C-peptide, and the possible correlation between these two hormones in previously diagnosed type 2 diabetes mellitus (T2DM) patients. In total, 20 age-, sex-, and body mass index- (BMI-) matched normal glucose tolerance (NGT) subjects and 120 previously diagnosed T2DM patients were included in this study. …”
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Psychosocial factors that predict happiness: A multigroup path analysis by Juan Martell-Muñoz, José Fernando Mora-Romo, David Luna, Filiberto Toledano-Toledano

“…Multigroup analysis identified differences in these effects, where participant sex, marital status and religion were moderating variables. …”
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Molecular Monitoring of Flavivirus Infections (West Nile Virus and Dengue Virus) Among Culicidae Mosquitoes in Southern Iran by Masoumeh Amin, Hamideh Edalat, Hamidreza Basseri, Morteza Zaim, Kourosh Azizi, Mostafa Salehi- Vaziri, Sahar Khakifirouz, Mohsen Kalantari, Mozaffar Vahedi, Saideh Yousefi, Parisa Amin

“…Molecular screening was conducted on the 8212 mosquitoes grouped into 150 pools based on sex, species, and trapping location. None of the pools tested were positive for Flavivirus RNA.Conclusion: This study highlights the importance of monitoring mosquito species distribution and emphasizes the need for enhanced Flavivirus surveillance and long-term monitoring programs in the region to understand the risk of disease transmission better.…”
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Association of clinical knowledge with patient care ownership among resident physicians: a nationwide cross-sectional study in Japan by Hirohisa Fujikawa, Hidetaka Tamune, Yuji Nishizaki, Taro Shimizu, Yu Yamamoto, Kiyoshi Shikino, Miwa Sekine, Hiroyuki Kobayashi, Yasuharu Tokuda

“…We conducted multivariable linear regression analysis, controlling for postgraduate years, sex, number of assigned inpatients, weekly working hours, type of hospital, and size of hospital. …”
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Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi by Mireia Larrosa-Godall, Joshua X. D. Ang, Philip T. Leftwich, Estela Gonzalez, Lewis Shackleford, Katherine Nevard, Rob Noad, Michelle A. E. Anderson, Luke Alphey

“…Several promising suppression drives have been developed in An. gambiae that target the sex determination gene doublesex (dsx). Methods In this study, a geographically confineable gene drive system targeting dsx was developed (dsx gRNA ). …”
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Dietary index for gut microbiota and its protective role against kidney stones: evidence of diabetes as a mediator from NHANES cross-sectional data by Lei Wang, Junjun Wu, Ziwen Jiang, Chao Wang, Fuxiang Lin, Yuxiang Zhong, Pengpeng Zhao, Wei Wei, Jianhua Huang, Zhanping Xu

“…Mediation analysis evaluated diabetes’s contribution to this relationship, and subgroup analyses were conducted based on sex, race/ethnicity, and alcohol consumption.ResultsHigher DI-GM scores were associated with lower KS prevalence (adjusted OR: 0.78, 95% CI: 0.65–0.92 per SD increase). …”
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Prevalence of Depression and Sleep Disorders in Patients on Dialysis: A Cross-Sectional Study in Qatar by Fadwa Al-Ali, Mostafa Elshirbeny, Abdullah Hamad, Ahmad Kaddourah, Tarek Ghonimi, Rania Ibrahim, Tarek Fouda

“…Our secondary aim was to study the associations of age, sex, and comorbid conditions with the QOL measures. …”
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Lack of Male-Female Differences in Disposition and Esterase Hydrolysis of Ramipril to Ramiprilat in Healthy Volunteers after a Single Oral Dose by Tom B. Vree, Erik Dammers, Ivan Ulc, Stefan Horkovics-Kovats, Miroslav Ryska, IJsbrand Merkx

“…This variation in the terminal half-life of ramiprilat is not sex related. In all three groups of half-lives, the corresponding Cmax values (mean � SD) of ramiprilat in males and females were identical. …”
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Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis by Shasha Huang, Shumin He, Fei Xiao, Yang Zhou, Su Lyu

“…Methods Peripheral blood was collected from 5 children with FM and 5 sex- and age-matched healthy controls; total RNA was extracted from each sample, and the extracted RNA from each group was pooled. …”
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Revealing the limitations of 10-year MACE observations: 20-year observed total cardiovascular burden in the EPIC-Norfolk study by Frank LJ Visseren, Harald T Jorstad, Marjolein Snaterse, S Matthijs Boekholdt, Tinka J van Trier, Jannick AN Dorresteijn, Manon van den Bogaart, Wilma JM Scholte op Reimer, Ron JG Peters

“…Therefore, we aimed to quantify how well 10-year observed incidence reflects 20-year observed incidence and how MACE reflects total CVD events across demographic groups, using observations in long-term prospective data.Methods In individuals aged 40–79 without CVD or diabetes from the population-based EPIC-Norfolk cohort, we compared the first occurrence of 10 and 20 years (1) 3-point MACE events (non-fatal myocardial infarction+non-fatal stroke+fatal CVD) and (2) total CVD events (all non-fatal and fatal CVD events leading to hospitalisation), stratified by sex and age.Results Among 22 569 participants (57% women), incident 10-year and 20-year 3-point MACE was 5.3% and 15.5%, respectively, yielding 20/10 year ratios from 2.2 (in older men) to 4.5 (in younger women). …”
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Effects of early supplemental parenteral nutrition on new-onset infection in adults with acute severe stroke: a single-center retrospective case–control study by Chen Ma, Zhirong Fan, Xuan Wang, Bian Li, Jingjing Zhao, Xiaogang Kang, Wen Jiang, Fang Yang

“…Forty control patients in the EN group who received full EN were matched by age, sex and lesion site. The time to new-onset pneumonia or nosocomial infections was analyzed by Student’s t test and the Breslow generalized Wilcoxon test. …”
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Analysis of Peripapillary and Macular Choroidal Thickness in Eyes with Pseudoexfoliative Glaucoma and Fellow Eyes by Fan Li, Qingli Shang, Guangxian Tang, Hengli Zhang, Xiaowei Yan, Lihua Ma, Yulei Geng, Qing Zhang

“…This case-control study included 37 PXG patients (group A: 37 PXG eyes; group B: 37 nonexfoliative fellow eyes) and 37 sex-, age-, and axial length-matched healthy volunteer eyes (group C). …”
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Smokeless tobacco: knowledge, attitudes and usage in Pakistan by Hammad Atif Irshad, Sajjan Raja, Hamzah Jehanzeb, Wamiq Ali Shaikh, Umair Saleem, Shahzil Abdur Rehman Malik, Akmal Shahzad, Mamoon Shaikh, Nousheen Iqbal, Javaid Ahmed Khan

“…Results Data was collected from 1,195 participants among which 85.86% of participants had heard of SLTs prior to the survey. Sex, province, household income and previous doctor visits were significant determinants to product knowledge through which 72.55% agreed that these products can lead to serious illnesses but 30% noted a lack of knowledge on legality. …”
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Childhood BMI trajectories and sociodemographic factors in an Italian pediatric population by Erich Batzella, Joaquin Gutierrez de Rubalcava Doblas, Gloria Porcu, Silvia Bressan, Elisa Barbieri, Carlo Giaquinto, Anna Cantarutti, Cristina Canova

“…Females, children residing in Southern and Island regions, and those from more deprived socioeconomic areas had a higher probability of following the “overweight-to-obese” group compared to the “normal-weight” trajectory. Sex and area of residence had similar effects on the “stable-moderate-increase” trajectory. …”
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Segmental analysis of human hair reveals intra-annual variation in 25(OH)D3 concentrations in modern and archaeological individuals by Kate Britton, Orsolya Czére, Eléa Gutierrez, Linda M. Reynard, Eamon Laird, Gary Duncan, Baukje de Roos

“…For the remaining participants, no statistically-significant correlations were determined between mean hair 25(OH)D3 levels and self-reported data, including age, sex, BMI, vitamin D supplementation, frequency of oily fish consumption, and hours spent outside. …”
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