Characterising SRD5A2 Gene Variants in 37 Indonesian Patients with 5-Alpha-Reductase Type 2 Deficiency by Nanis S. Marzuki, Firman P. Idris, Hannie D. Kartapradja, Alida R. Harahap, Jose R. L. Batubara

“…In the current study, we analysed 37 subjects diagnosed with 46,XY DSD (disorders of sex development) with confirmed variations in the SRD5A2 gene. …”
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Significant Association between Serum Interleukin-6 and Helicobacter pylori Antibody Levels among H. pylori-Positive Japanese Adults by Hiroko Nakagawa, Takashi Tamura, Yoko Mitsuda, Yasuyuki Goto, Yoshikazu Kamiya, Takaaki Kondo, Kenji Wakai, Nobuyuki Hamajima

“…In multiple linear regression analysis adjusting for sex and age, the serum IL-6 level was still significantly associated with the IgG level in all subjects (β=0.18, P=0.012). …”
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Achieving prediabetes reversal in China: a nationwide longitudinal study on the role of blood glucose and lipid management in middle-aged and elderly adults by Hongguang Yang, Yao Liu, Zhenhe Huang, Guifang Deng

“…The stepwise logistic regression model identified older age, female sex, abdominal obesity (OR 0.70, 95% CI 0.57–0.86), elevated LDL-C (OR 0.69, 95% CI 0.48–0.97), higher FPG (OR 0.68, 95% CI 0.52–0.90), and higher HbA1c (OR 0.23, 95% CI 0.18–0.30) as factors associated with regression to NGR. …”
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Evaluating handgrip strength and functional tests as indicators of gait speed in older females by Valentina Muollo, Samuel D’Emanuele, Laura Ghiotto, Doriana Rudi, Federico Schena, Cantor Tarperi

“…., gait speed (GS)] compared to males, highlighting the need for sex-difference considered in screening and intervention planning. …”
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Impact of the COVID-19 pandemic on the volume and diagnoses of patients admitted to the paediatric emergency department: a retrospective analysis from a third-level hospital in Nor... by Paulina Blanco-Murillo, Ricardo J Estrada-Mendizabal, Katheryne Paola Madrazo-Aguirre, Manuel Guillermo Ruelas-Martinez, Lucia Escobedo-Berumen, Rommy Elizabeth Pineda-Magaña, Maria Guadalupe Garcia-Lima, Oscar Tamez-Rivera

“…Other variables, such as age, sex and comorbidities, were analysed. χ2 and Mann-Whitney U tests were used depending on the examined variable.Results There was a 44.1% decrease in the total volume of patients admitted to the paediatric ED during the analysed pandemic period. …”
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General practitioners’ clinical decision-making in patients that could have cancer: a vignette study comparing the Baltic states with four Nordic countries by Alexander Rosendahl, Anet Vanaveski, Liina Pilv-Toom, Jānis Blumfelds, Vija Siliņa, Mette Brekke, Tuomas Koskela, Aurimas Rapalavičius, Hans Thulesius, Peter Vedsted, Michael Harris

“…This study investigated the likelihood of General Practitioners (GPs) investigating or referring patients with a low but significant risk of cancer in these two regions, and how this was affected by GP demographics.Design A survey of GPs using clinical vignettes.Setting General Practice in Denmark, Estonia, Finland, Latvia, Lithuania, Norway, and Sweden.Subjects General Practitioners.Outcome measures A regional comparison of GPs’ stated immediate diagnostic actions (whether or not they would perform a key diagnostic test and/or refer to a specialist) for patients with a low but significant risk of cancer (between 1.2 and 3.6%).Results Of the 427 GPs that completed the questionnaire, those in the Baltic states, and GPs that were more experienced, were more likely to arrange a key diagnostic test and/or refer their patient to a specialist than those in Nordic Countries or who were less experienced (p < 0.001 for both measures). Neither GP sex nor practice location within a country showed a significant association with these measures.Conclusion While relative one-year cancer survival rates are lower in the Baltic states than in four Nordic countries, we found no evidence that this is due to their GPs’ reluctance to take immediate diagnostic action, as GPs in the Baltic states were more likely to investigate and/or refer at the first consultation. …”
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Relationship between Lower Urinary Tract Dysfunction and Clinical Features in Chinese Parkinson’s Disease Patients by Duo Xu, Shunchang Han, Jue Wang, Juan Feng

“…Next, correlations between the OABSS and patient sex, age, age of onset, disease duration, MDS-UPDRS-III, H-Y stage, PD subtype, treatment, education, and nonmotor symptoms were analyzed to identify factors correlated with LUT dysfunction. …”
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Exploring the drivers of adolescent sexual and reproductive healthcare-seeking behavior in northwestern Botswana: a cross-sectional analysis by Mackenzie Lawson, Helen Apps, Peggie Ramaphane, Francis Barchi

“…The most common reasons for forgoing visits reflected perceptions that nurses were unfriendly and did not believe adolescents should have sex. Students identified logistical barriers, including not knowing where to go, long distances to services, and limited operating hours. …”
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Hematohidrosis in Pediatric Practice  – a Case Report and Review of the Literature by Oksana Matsyura, Lesya Besh, Svitlana Jefimova, Khrystyna Slivinska-Kurchak, Sergiy Gerasymov

“…We took into consideration: age of the patient, sex, location of bloody excretion, cause or trigger, treatment and its effectiveness.Our clinical case present a 9-year-old girl complained of a periodic bleeding from the intact skin of the face, neck, thighs (without visible damage to the skin) manifested by red or pink liquid, nosebleeds, and bloody discharge from the mucous membrane of the eyes. …”
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Abnormal Baseline Brain Activity in Patients with Pulsatile Tinnitus: A Resting-State fMRI Study by Lv Han, Liu Zhaohui, Yan Fei, Li Ting, Zhao Pengfei, Du Wang, Dong Cheng, Guo Pengde, Han Xiaoyi, Wang Xiao, Li Rui, Wang Zhenchang

“…The present study used unilateral PT patients (n=42) and age-, sex-, and education-matched normal control subjects (n=42) to investigate the changes in structural and amplitude of low-frequency (ALFF) of the brain. …”
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Clinical Features and Visual Outcomes of Optic Neuritis in Chinese Children by Huanfen Zhou, Wei Wang, Quangang Xu, Shaoying Tan, Shuo Zhao, Mo Yang, Chunxia Peng, Shihui Wei

“…The other features of this cohort, such as sex, experienced bilateral attack, VA at presentation, presence of optic disc edema, systemic diseases, magnetic resonance imaging (MRI) findings, and aquaporin-4 (AQP-4) antibody status, were not significantly correlated with the final visual outcome. …”
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A multiresolution approach with method-informed statistical analysis for quantifying lymphatic pumping dynamics by Mohammad S. Razavi, Katarina J. Ruscic, Elizabeth G. Korn, Marla Marquez, Timothy T. Houle, Dhruv Singhal, Lance L. Munn, Timothy P. Padera

“…This approach not only offers detailed insights into lymphatic pumping behaviors across species, sex and age, but also significantly boosts the reliability of these measurements by incorporating multiple regions of interest and evaluating the lymphatic system under various gravitational loads. …”
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Clinical Features of Human Parvovirus B19-Associated Encephalitis Identified in the Dakar Region, Senegal, and Viral Genome Characterization by Al Ousseynou Seye, Fatou Kiné Top, Maimouna Mbanne, Moussa Moise Diagne, Ousmane Faye, Amadou Alpha Sall, Ndongo Dia, Jean-Michel Heraud, Martin Faye

“…The mean age was 16.7 years among B19V-positive patients, with a higher prevalence in 0–5-year-old children and the sex ratio (male/female) was 2.25. The B19V-positive patients mainly exhibited hypoleukocytosis, normal glycorrhachia, and normal proteinorrachia in the cerebrospinal fluid. …”
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Salivary Protein Profile and Food Intake: A Dietary Pattern Analysis by Teresa Louro, Carla Simões, Wilmara Lima, Laura Carreira, Paula Midori Castelo, Henrique Luis, Pedro Moreira, Elsa Lamy

“…Dietary habits were assessed in 122 adults (61 from each sex, with ages ranging from 20 to 59 years) using Food Frequency Questionnaires. …”
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Methylation and Expression of Retinoblastoma and Transforming Growth Factor-β1 Genes in Epstein-Barr Virus-Associated and -Negative Gastric Carcinomas by Xia Liu, Xiuming Tang, Shaoyan Zhang, Yun Wang, Xiaofeng Wang, Chengquan Zhao, Bing Luo

“…RB methylation, loss expression of RB, and TGF-β1 expression were significantly associated with tumor invasion and lymph node metastasis (P<0.05), but was not associated with sex, age, histological subtype (differentiation status) and tumor location. …”
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Brief Report: Precision Language and Deletion of the “S” Word by Ciara Lockstadt, MD, Mary M. Pasquinelli, DNP, Jill Feldman, MD, Jamie L. Studts, PhD, Jamie S. Ostroff, PhD, Li Liu, PhD, Ella A. Kazerooni, MD, Robert A. Smith, PhD, Lisa Carter-Bawa, PhD, Lawrence E. Feldman, MD

“…We conducted internet searches to gather presenters’ stated home continent, sex, specialty, and professional degree. Results: Of 177 presentations that discussed smoking status, 77 presenters used non-stigmatizing language, whereas 100 presenters used the stigmatizing term “smoker.” …”
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Association between Visual Acuity and Retinal Layer Metrics in Diabetics with and without Macular Edema by LakshmiPriya Rangaraju, Xuejuan Jiang, J. Jason McAnany, Michael R. Tan, Justin Wanek, Norman P. Blair, Jennifer I. Lim, Mahnaz Shahidi

“…The associations among VA and retinal layer metrics were determined by multivariate linear regressions after adjusting for covariates (age, sex, race, HbA1c, diabetes type, and duration) and correcting for multiple comparisons. …”
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Cervical cancer burden and attributable risk factors across different age and regions from 1990 to 2021 and future burden prediction: results from the global burden of disease stud... by Lu-yao Cheng, Ji-qi Zhao, Ting-ting Zou, Zhong-hua Xu, Yin Lv

“…The risk factors, which included unsafe sex and smoke, significantly varied by region. The global ASIR exhibited a downward trend from 2021 to 2035.ConclusionFrom 1990 to 2021, although the overall trend in incidence, mortality, and DALYs of CC exhibited a global and regional downward trend, there were significant disparities among areas with different socioeconomic development. …”
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Assessment of programmed cell death 1 and its programmed cell death ligand 1 levels in vitiligo by Hanan R. Nada, Ahmed Mourad, Laila A. Rashed, Ghada M. El-Hanafy, Nermeen M.A. Abdallah, Mohamed M. Abdelhady

“…Patients and methods A total of 30 vitiliginous patients and 30 age and sex-matched controls were included. Full history and clinical examination were done and ELISA measured tissue levels of PD-1 and PD-L1 from lesional and nonlesional biopsies. …”
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Validation of the shortest version of the eating attitude test (EAT-7) as a screening tool for disordered eating in patients with first-episode schizophrenia by Feten Fekih-Romdhane, Youssef Boukadida, Majda Cheour, Souheil Hallit

“…Measurement invariance of the EAT-7 across sex groups was tested using multi-group CFA, and established at the configural, scalar, and metric levels. …”
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