Defining the high-risk category of patients with cutaneous melanoma: a practical tool based on prognostic modeling by Oleksandr Dudin, Oleksandr Dudin, Ozar Mintser, Vitalii Gurianov, Nazarii Kobyliak, Nazarii Kobyliak, Denys Kozakov, Sofiia Livshun, Oksana Sulaieva, Oksana Sulaieva

“…This drives to identification of prognostic biomarkers for predicting CM recurrence to guide appropriate treatment in patients with localized melanoma.AimThis study aimed to develop a prognostic model for assessing the risk of recurrence in patients with CM, enabling prompt prognosis-driven further clinical decision-making for high-risk patients.Materials and methodsThis case-control study included 172 patients with CM recurrence (high-risk group) and 30 patients with stable remission (low-risk group) 3 years after primary diagnosis. The impact of sex, age at diagnosis, anatomical site, histological characteristics (the histological type, pathological stage, ulceration; the depth of invasion, mitotic rate, lymphovascular invasion, neurotropism, association with a nevus, tumor-infiltrating lymphocyte density, tumor regression and BRAF codon 600 mutation status) on CM recurrence was evaluated.ResultsFive independent variables, including nodal status, a high mitotic rate, Breslow thickness, lymphovascular invasion, perineural invasion and regression features were identified as the most significant. …”
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Comorbidity patterns and mortality in atrial fibrillation: a latent class analysis of the EURopean study of Older Subjects with Atrial Fibrillation (EUROSAF) by Huah Shin Ng, Richard Woodman, Nicola Veronese, Alberto Pilotto, Arduino A. Mangoni

“…Compared to phenotype 1, after adjusting for age, sex, use of anticoagulants, cardiovascular medications, and proton pump inhibitors, and individual MPI domains, phenotype 3 had a significantly higher risk of mortality (adjusted hazard ratio = 1.27, 95% CI = 1.01 to 1.60). …”
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Association between BDNF rs6265 and Obesity in the Boston Puerto Rican Health Study by Xian-Yong Ma, Wei Qiao Qiu, Caren E. Smith, Laurence D. Parnell, Zong-Yong Jiang, Jose M. Ordovas, Katherine L. Tucker, Chao-Qiang Lai

“…In summary, BDNF rs6265 is differentially associated with obesity risk by sex and interacts with PUFA intake influencing obesity traits in Boston Puerto Rican men.…”
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CT-based scoring system for diagnosing eosinophilic solid and cystic renal cell carcinoma versus clear cell renal cell carcinoma by Sunya Fu, Dawei Chen, Yuqin Zhang, Yuguo Wei, Yuning Pan

“…The two groups were matched on a 1:2 basis using the propensity-score-matching (PSM) method, with matching factors including sex and age. Finally, 25 ESC-RCC and 50 ccRCC cases were included and randomly divided into a training cohort (52 cases) and a validation cohort (23 cases). …”
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Enhancing trauma triage in low-resource settings using machine learning: a performance comparison with the Kampala Trauma Score by Mike Nsubuga, Timothy Mwanje Kintu, Helen Please, Kelsey Stewart, Sergio M. Navarro

“…The RF model demonstrated the highest accuracy at 0.69 (95% CI: 0.68–0.70), while the KTS-based model showed an accuracy of 0.54 (95% CI: 0.52–0.55). Sex, hours to hospital, and age were identified as the most significant predictors in both ML models. …”
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Markers of Anemia in Children with Type 1 Diabetes by Ewa Rusak, Anna Rotarska-Mizera, Piotr Adamczyk, Bogdan Mazur, Joanna Polanska, Agata Chobot

“…Methods. 94 (59% ♀) T1D children without other autoimmune disorders, aged 12.5 ± 4.1 years, T1D duration: 4.2 ± 3.6 years, HbA1c 7.3 ± 1.5% (57 ± 12.6 mmol/mol). Sex- and age-matched controls (43 children). In all children, anthropometric measurements, the blood count, iron turnover parameters, and vitamin B12 concentration were taken. …”
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A longitudinal study to COVID-19 infection among university students: Physical fitness changes and psychological responses by Yuning Hao, Jay Lee, Water Soi Po Wong, Frankie U. Kei Wong, Walter Heung Chin Hui, Gasper Chi Hong Leong, Zhaowei Kong

“…Regarding mental health, a notable difference was observed in sleep quality, with the positive group scoring 19 % higher than the negative group (p < .05, d = .44). Sex (β = .164, p < .05), previous infection (β = .277, p = .019) and anxiety (β = .373, p = .002) were predictive of PSQI scores, accounting for 37.5 % of the variance. …”
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Genetic polymorphisms and related risk factors of ischemic stroke in a Mongolian population in China by Q. Wu, H. Wu, Yu. L. Orlov, G. Gegentana, W. Huo, A. O. Bragin, N. Wu, S. Suyalatu, F. Zhao, J. Zhao, L. E. Tabikhanova, M. Chen, H. Bai

“…ALDH2 gene encodes mitochondrial aldehyde dehydrogenase, involved in the oxidative pathway of alcohol metabolism. Sex, age, body mass index and high blood pressure might be the risk factors. …”
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KNOWLEDGE, ATTITUDES AND PRACTICES TOWARDS OPEN EDUCATIONAL RESOURCES IN HIGHER EDUCATION INSTITUTIONS IN THE PHILIPPINES by Liezel G. Mohillo, Angie R. Jalandoon, Dave E. Marcial

“…In contrast, print and nonprint resources can positively affect KAP. While sexes, highest educational attainment, and number of years of service shows no difference. …”
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The Association between Ambient Fine Particulate Matter and Oral Neoplasm among Smokers and Betel Quids Chewers by Mei-Sheng Ku, Pallop Siewchaisakul, Amy Ming-Fang Yen, Chen-Yu Liu

“…We used the Bayesian random-effect logistic regression model to assess the association between PM2.5 and OPMD/OC. After adjusting for sex, age, and behavior of betel quid chewing and cigarette smoking, we found that subjects from areas of higher levels of PM2.5 (≥ 35 µg m−3) had an increased risk of OPMD/OC and OC by 11% (aRR = 1.11; 95% CI: 1.09–1.13) and 55% (aRR = 1.55; 95% CI: 1.49–1.60) respectively, compared to those from areas of lower PM2.5 (< 35 µg m−3). …”
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Epidemiological and Clinical Profile of Dermatoses Observed in Chronic Hemodialysis Patients at the National Teaching Hospital (NTH-HKM) of Cotonou, Benin by Hugues Adégbidi, Fabrice Akpadjan, Odile Houngbo, Jacques Vigan, Bérénice Dégboé, Nadège Agbessi, Christiane Koudoukpo, Félix Atadokpèdé

“…Results. 87 patients were included in the study for a hospital frequency of 33.8%. The sex ratio (male to female) was 2. The median age was 49 years (IQ [40.75–59]). …”
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SOX7 is involved in polyphyllin D-induced G0/G1 cell cycle arrest through down-regulation of cyclin D1 by Zheng Bin, Wang Gang, Gao Wenbo, Wu Qiquan, Zhu Weizhi, Weng Guobin

“…Our previous study showed that the sex-determining region Y-box 7 (SOX7) was low-expressed and served as a tumor suppressor in PCa cells. …”
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Quality of Life Philosophy VI. The Concepts by Soren Ventegodt, Niels Jørgen Andersen, Joav Merrick

“…The about a hundred central concepts related to research in the global quality of life can, in a holistic medical frame of interpretation, be organized under ten abstract key concepts: existence, creation of the world, state of being, daily living, talents, relations, sex, health, personal development, and therapy with subthemes as discussed in this paper. …”
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Using a Two-Steps Clustering and PCA Analysis for Stratified Chronic Non-Cancer Pain Care: A Retrospective Cross-Sectional Study by Peiró AM, Barrachina J, Escorial M, Aguado I, Margarit C, Grimby-Ekman A

“…Being older than 65 years old, retired or on medical leave, under opioids and anxiolytic prescription, had a severe impact on daily quality of life without any sex-difference.Conclusion: These clusters based on real-world clinical information might be useful for screening even more where the access to physical exploration is limited. …”
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Development of a Brief Assessment Tool to Evaluate Early Low Nutrition Risk in Community Elderly: Creation of the Tool and Examination of Its Reliability and Criterion-related Vali... by Shoji Shinkai, Miki Narita, Hiroshi Murayama, Akihiko Kitamura, Yoshinori Fujiwara

“…Furthermore, Spearman’s partial rank correlation coefficients (sex- and age-adjusted) between the created index and important health indicators were examined to determine the criterion-related validity. …”
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Climate of origin influences how a herbivorous mite responds to drought-stressed host plants by Migeon, Alain, Auger, Philippe, Fossati-Gaschignard, Odile, Hufbauer, Ruth A, Miranda, Maëva, Zriki, Ghais, Navajas, Maria

“…We evaluated how plant drought stress affects four life history traits: development time, fecundity, sex-ratio and emigration rate in an experiment comparing well-watered and drought-stressed bean plants. …”
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Utilization of Interphalangeal Joint Arthroplasty and Arthrodesis in the United States From 2010 to 2019 by Erica L. Smearman, MD, PhD, Anthony L. Karzon, MD, Hayden L. Cooke, BS, Zaamin B. Hussain, MD, EdM, Musab Gulzar, BS, Nina Suh, MD, Michael B. Gottschalk, MD, Eric R. Wagner, MD, MS

“…Volume and incidence were estimated annually and according to sex, age, and US geographical region for 2010 and 2019. …”
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The prevalence of thiamine deficiency among elderly nursing home residents: A cross‐sectional study by Nozomu Uchida, Mayumi Ishida, Izumi Sato, Akira Yoshioka, Takao Takahashi, Daisuke Furuya, Yasuhiro Ebihara, Hiroshi Ito, Hideki Onishi

“…Blood thiamine concentrations were measured using a high‐performance liquid chromatography method, with TD defined as a concentration of <21.3 ng/mL. Basic data (age, sex, height, weight, and BMI), dietary intake for the previous 3 weeks, degree of care (DOC), degree of independence in daily life for elderly with dementia (DIDLED), and comorbidities were analyzed using descriptive statistical methods. …”
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Clinical importance of borderline proteinuria in nonazotemic cats and evaluation of other risk factors for the development of chronic kidney disease by Femke Mortier, Sylvie Daminet, Sofie Marynissen, Joren Verbeke, Dominique Paepe

“…Univariable and multivariable Cox models were fit to determine the relationship between development of renal disease and potential risk factors such as age, sex, breed, weight, dental disease, blood pressure, serum creatinine concentration (sCrea), serum symmetric dimethylarginine concentration (sSDMA), blood urea nitrogen concentration, urine specific gravity (USG), and UPC. …”
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Social Cognition in Patients with Early-Onset Parkinson’s Disease by Ana Natalia Seubert-Ravelo, Ma Guillermina Yáñez-Téllez, María Lizbeth Lazo-Barriga, Alejandra Calderón Vallejo, Carlos Eduardo Martínez-Cortés, Adela Hernández-Galván

“…Twenty-five nondemented patients with EOPD and 25 controls matched for sex, age, and educational level were enrolled. A battery that included six SC tests was administered to all study participants; a decision-making scale was completed by participants’ partners. …”
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