N-Acetylcysteine and Other Sulfur-Donors as a Preventative and Adjunct Therapy for COVID-19 by Heidi N du Preez, Colleen Aldous, Hendrik G Kruger, Lin Johnson

“…The airway epithelial glycocalyx plays an important role in preventing severe acute respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial glycocalyx contributes to vascular permeability and tone, as well as modulating immune, inflammatory, and coagulation responses. …”
Get full text

Advancements in the development of antivirals against SARS-Coronavirus by Mrityunjay Kumar, Mirza Sarwar Baig, Kanchan Bhardwaj, Kanchan Bhardwaj

“…Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) caused an outbreak in 2002-2003, spreading to 29 countries with a mortality rate of about 10%. …”
Get full text

Molecular Modeling and Simulation Analysis of Antimicrobial Photodynamic Therapy Potential for Control of COVID-19 by Maryam Pourhajibagher

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter the host cells by binding the viral surface spike glycoprotein (SG) to angiotensin-converting enzyme 2. …”
Get full text

Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults by Jung Hyuk Lee, Yuna Shin, Kwang-Soo Shin, Ju Yeon Park, Mi Sun Kim, Young-Shin Park, Wuhyun Kim, Joon Young Song, Ji Yun Noh, Hee Jin Cheong, Chang-Yuil Kang, Sang Hwan Seo, Jae-Ouk Kim, Deok Ryun Kim, Nathaniel S. Hwang, Jae Seung Yang, Jerome H. Kim, Byoung-Shik Shim, Manki Song

“…ABSTRACT AdCLD-CoV19-1, a chimeric adenovirus-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, was previously reported to elicit robust antibody responses in mice and non-human primates after a single dose. …”
Get full text

Clustering of countries in terms of deaths and cases of COVID-19 by Ozge PASIN, Tugce PASIN

“…Introduction: The novel coronavirus ‘Severe Acute Respiratory Syndrome Coronavirus Type 2’ (SARS- CoV-2), responsible for the disease termed as ‘Coronavirus disease 2019’ (COVID-19 pandemic) first broke out in Wuhan, Hubei province, mainland China. …”
Get full text

Detection of COVID-19 Using Protein Sequence Data via Machine Learning Classification Approach by Siti Aminah, Gianinna Ardaneswari, Mufarrido Husnah, Ghani Deori, Handi Bagus Prasetyo

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in late 2019 resulted in the COVID-19 pandemic, necessitating rapid and accurate detection of pathogens through protein sequence data. …”
Get full text

In Silico Study of Alkaloids: Neferine and Berbamine Potentially Inhibit the SARS-CoV-2 RNA-Dependent RNA Polymerase by Rishab Marahatha, Asmita Shrestha, Kabita Sharma, Bishnu P. Regmi, Khaga Raj Sharma, Pramod Poudel, Ram Chandra Basnyat, Niranjan Parajuli

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, has been a global concern. …”
Get full text

Comprehensive review of preclinical evaluation strategies for COVID-19 vaccine candidates: assessing immunogenicity, toxicology, and safety profiles by Delaram Doroud, Mojtaba Daneshi, Fatemeh Kazemi-Lomedash, Zohre Eftekhari

“… Following the worldwide spread of Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), there is a vital requirement for safe and effective vaccines against Coronavirus disease 2019 (COVID-19). …”
Get full text

A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation by Jyotirmoy Sarker, Pritha Das, Sabarni Sarker, Apurba Kumar Roy, A. Z. M. Ruhul Momen

“…Recent studies have shown that transmembrane serine protease 2 (TMPRSS2), a protease known for similar role in previous coronavirus infections, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS), is responsible for the proteolytic cleavage of the SARS-CoV-2 spike protein, enabling host cell fusion of the virus. …”
Get full text

Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19 by Taravat Talebi, Tannaz Masoumi, Katayoun Heshmatzad, Mahshid Hesami, Majid Maleki, Samira Kalayinia

“…Previous investigations and studies revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and ACE2 have a considerable association. …”
Get full text

Genome analysis and prevalence of SARS-CoV-2 Indonesian variants and the correlation with the outbreak timeline by Maria Prevyolita Indra Muliawan, Timotius Christopher Tantokusumo, Amalda Siti Anisa, Kholis Abdurachim Audah

“… Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has undergone multiple mutations, leading to the development of various variants. …”
Get full text

Outbreak prediction of covid-19 in most susceptible countries by D. Yadav, H. Maheshwari, U. Chandra

“…The full name of the coronavirus is severe acute respiratory syndrome SARS-CoV. It spread on humans as well as animals and infected more than 183 countries with 2959927 confirm cases and 202733 deaths till 28 April 2020. 84 days data is used to predict confirmed and death cases for the next 10 days by using prophet and daily average based algorithm. …”
Get full text

Natural compounds from medicinal plants against COVID-19 by Anton Kolodnitsky, Nikita Ionov, Irina Gravel, Vladimir Poroikov

“…The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), known to cause the coronavirus disease 2019 (COVID-19), was declared a pandemic in early 2020. …”
Get full text

Immunoinformatics Identification of B- and T-Cell Epitopes in the RNA-Dependent RNA Polymerase of SARS-CoV-2 by Niti Yashvardhini, Amit Kumar, Deepak Kumar Jha

“…SARS-CoV-2 (Severe acute respiratory syndrome coronavirus-2) is a newly emerged beta coronavirus and etiolating agent of COVID-19. …”
Get full text

From the Role of Microbiota in Gut-Lung Axis to SARS-CoV-2 Pathogenesis by Sara Ahmadi Badi, Samira Tarashi, Abolfazl Fateh, Pejman Rohani, Andrea Masotti, Seyed Davar Siadat

“…Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is responsible for the outbreak of a new viral respiratory infection. …”
Get full text

Hormonal Implications of SARS-CoV-2: A Review of Endocrine Disruptions by Aliya Yskak, Yevgeniy Sokharev, Kuanysh Zhumalynov, Elizaveta Koneva, Natalia Afanasyeva, Dmitri Borodulin, Dmitrii Babaskin, Almabek Nugmanov, Murat Nurushev, Vadim Chashkov

“…To improve medical care and rehabilitation algorithms for patients affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is important to evaluate and summarize the available data on the effect of coronavirus infection (COVID-19) on the endocrine system. …”
Get full text

Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection. by Xiaoyuan Lin, Beibei Fu, Yan Xiong, Na Xing, Weiwei Xue, Dong Guo, Mohamed Zaky, Krishna Pavani, Dusan Kunec, Jakob Trimpert, Haibo Wu

“…Coronavirus disease 2019 is a respiratory infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Evidence on the pathogenesis of SARS-CoV-2 is accumulating rapidly. …”
Get full text

An Overview on the Role of Relative Humidity in Airborne Transmission of SARS-CoV-2 in Indoor Environments by Ajit Ahlawat, Alfred Wiedensohler, Sumit Kumar Mishra

“…Abstract COVID-19 disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, China and spread with an astonishing rate across the world. …”
Get full text

A comparative analysis of the binary and multiclass classified chest X-ray images of pneumonia and COVID-19 with ML and DL models by Pal Madhumita, Mohapatra Ranjan K., Sarangi Ashish K., Sahu Alok Ranjan, Mishra Snehasish, Patel Alok, Bhoi Sushil Kumar, Elnaggar Ashraf Y., El Azab Islam H., Alissa Mohammed, El-Bahy Salah M.

“…The highly infectious coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2, the seventh coronavirus. …”
Get full text

COVID-19 Outbreak among Healthcare Workers in a Specialty Unit in a Low-Middle Income Setting by Regina E. Oladokun, Babatunde O. Ogunbosi, Oreoluwa E. Morakinyo

“…Data on demographics, clinical characteristics, and laboratory findings were collected using a structured proforma. Severe-acute-respiratory-syndrome-related coronavirus laboratory tests followed the World Health Organization recommendations, with nasopharyngeal swabs obtained for real-time reverse transcription–polymerase chain reaction. …”
Get full text