Antibacterial activity improvement in a point mutant K45E of the pepper defensin J1-1 by Gilberto Andrés Muñoz-Pérez, Francisco A. Guillén-Chable, Gerardo Corzo, Ivan Arenas-Sosa, Lucila A. Sánchez-Cach, Georgina Estrada

“…Together, our findings support the idea that amino acid sequence variability in plant defensins superfamily can generate major functional changes, and highlight the relevant role of charged residues, beyond the g-core loop, in the improvement of J1-1 antibacterial activity.…”
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Clinical and Laboratorial Features That May Differentiate 46,XY DSD due to Partial Androgen Insensitivity and 5α-Reductase Type 2 Deficiency by Nélio Neves Veiga-Junior, Pedro Augusto Rodrigues Medaets, Reginaldo José Petroli, Flávia Leme Calais, Maricilda Palandi de Mello, Carla Cristina Telles de Sousa Castro, Guilherme Guaragna-Filho, Letícia Espósito Sewaybricker, Antonia Paula Marques-de-Faria, Andréa Trevas Maciel-Guerra, Gil Guerra-Junior

“…The AR and SRD5A2 genes were sequenced in all cases. There were 9 cases (7 families) of 5α-RD2, 10 cases (5 families) of PAIS, and 39 patients had normal molecular analysis of SRD5A2 and AR genes. …”
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FAM210B activates STAT1/IRF9/IFIT3 axis by upregulating IFN-α/β expression to impede the progression of lung adenocarcinoma by Xuejuan Gao, Donglan Huang, Ying Liu, Gui Zhang, Xiaofen Zheng, Baiye Guan, Aiwen Chen, Jiayao Wu, Shi-Ming Luo, Zonghua Liu, Luxuan Chen, Xiaohui Liu, Jingjie Jin, Xingfeng Yin, Zhenghua Sun, Yunfang Zhang, Meizhi Lu, Gong Zhang, Wanting Liu, Langxia Liu

“…Abstract FAM210B (family with sequence similarity 210 member B) is a novel protein that has been linked to tumor development. …”
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Rabies re-emergence after long-term disease freedom (Amur Oblast, Russia) by A. D. Botvinkin, I. D. Zarva, I. V. Meltsоv, S. A. Chupin, E. M. Poleshchuk, N. G. Zinyakov, S. V. Samokhvalov, I. V. Solovey, N. V. Yakovleva, G. N. Sidorov, I. A. Boyko, V. G. Yudin, E. I. Andaev, A. Ye. Metlin

“…The first cases were detected within 30 km from the state border with China. Nucleotide sequences of the nucleoprotein gene of three rabies virus isolates were determined and their belonging to the Arctic-like-2 genetic lineage was established. …”
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Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02 by Gwendolin S. Simper, Gia-Gia T. Hò, Alexander A. Celik, Trevor Huyton, Joachim Kuhn, Heike Kunze-Schumacher, Rainer Blasczyk, Christina Bade-Döding

“…Functional pHLA complexes were purified; peptides were eluted and sequenced. Applying mass spectrometric analysis, CBZ and EPX were monitored by analyzing the heavy chain and peptide fractions separately for the presence of the drug. …”
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The geographical distribution, trophic modes, and host preferences of Fomitopsis pinicola in Central Europe: a comprehensive review by Gáper Ján, Gáperová Svetlana, Pristaš Peter, Šebesta Martin, Kollárová Patrícia, Gallay Igor, Slobodník Branko

“…In silico analysis of available F. pinicola ITS sequences indicates its genetic homogeneity in Central Europe and the adjacent regions. …”
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Genome Characterization of Mammalian Orthoreovirus and Porcine Epidemic Diarrhea Virus Isolated from the Same Fattening Pig by Xiaoxuan Li, Jiakai Zhao, Jingjie Li, Yangzong Xiri, Zhixiang Liu, Qin Zhao, Yani Sun

“…The viral RNA of MRV and PEDV was detected in the fecal samples. The genome sequences of MRV and PEDV were successfully amplified from the same fecal sample. …”
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Metasurface higher-order poincaré sphere polarization detection clock by Hui Yang, Kai Ou, Qiang Liu, Meiyu Peng, Zhenwei Xie, Yuting Jiang, Honghui Jia, Xinbin Cheng, Hui Jing, Yueqiang Hu, Huigao Duan

“…Conventional strategies for detecting SoP, which typically involves a sequence of cascaded optical elements, are bulky, complex, and run counter to miniaturization and integration. …”
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An In Vitro Study on Prestin Analog Gene in the Bullfrog Hearing Organs by Zhongying Wang, Minfei Qian, Qixuan Wang, Huihui Liu, Hao Wu, Zhiwu Huang

“…In the present study, we used the gerbil prestin sequence as a template and identified an analog gene in the bullfrog genome. …”
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Mapping 3D Overthrust Structures by a Hybrid Modeling Method by Weisheng Hou, Yanhua Li, Shuwan Ye, Songhua Yang, Fan Xiao

“…The loss functions of FCN and the conventional MPS method jointly form the kernel function of the proposed method, which is constrained by stratigraphic sequence and stratum thickness. The input and output parameters of the FCN are the coordinates and corresponding elevations of geological contacts, respectively. …”
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Dynamic cycles between brain states during creative storytelling by Xitong Liang, Mingnan Cai, Gaohan Jing, Chengming Zhang, Emily Sophia Nichols, Li Liu

“…The dual process model proposes that spontaneous thinking and deliberate thinking drive the dwell in and the transitions between different mental states during creative thinking, but there is a debate over whether the two types of thinking operate in parallel or in sequence. To address these gaps, we conducted a functional magnetic resonance imaging (fMRI) study in 41 college students during a creative storytelling task. …”
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Evidence of Helicobacter spp. in Saliva and Gastric Mucosa of Domestic Dogs in the Central Region of Rio Grande do Sul, Brazil by Daniel D. Guerra Segundo, Camila B. E. Mello, Juliana F. Cargnelutti, Mariana M. Flores, Luís F. Pedrotti, Bernardo N. Antunes, Vanessa Milech, Omar G. Velasquez, Letícia R. Martins, Saulo T. L. Pinto Filho

“…The samples possessed a high nucleotide identity with remarkably similar sequences among some of the species of NHPH such as H. heilmannii s.s., H. salomonis, H. felis, and H. bizzozeronii. …”
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Telomere length varies with sex, hatching rank and year of birth in the Little Owl, Athene noctua by Criscuolo, François, Fache, Inès, Scaar, Bertrand, Zahn, Sandrine, Bleu, Josefa

“…Telomeres are non-coding DNA sequences located at the end of linear chromosomes, protecting genome integrity. …”
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Optimizing insecticide application for effective fall armyworm (Spodoptera frugiperda) management in Sorghum: a field study on spray frequency and rates by Aderajew Mihretie, Admasie Kassaw, Abebe Ayalew, Abate Abtie, Abiye Tiruneh, Mequanint Andualem Mekonnen

“…However, for Sirinka, further research is necessary to explore the optimal spray sequence or total number of applications required for effective management of FAW in Sorghum.…”
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Two-Echelon Multidepot Logistics Network Design with Resource Sharing by Siyu Luo, Yong Wang, Jinjun Tang, Xiangyang Guan, Maozeng Xu

“…Furthermore, a Shapley value method is used for allocating total profits of established alliances and finding an optimal coalition sequence of the logistics facilities joining alliances based on the strictly monotonic path strategy. …”
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Prediction of influenza A virus-human protein-protein interactions using XGBoost with continuous and discontinuous amino acids information by Binghua Li, Xin Li, Xiaoyu Li, Li Wang, Jun Lu, Jia Wang

“…In this article, we developed a sequence-based machine learning method for predicting PPI. …”
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Bioinformatics Based Drug Repurposing Approach for Breast and Gynecological Cancers: RECQL4/FAM13C Genes Address Common Hub Genes and Drugs by Gizem Ayna Duran

“…Results: The RecQ Like Helicase 4 and Family with Sequence Similarity 13 Member C genes were found to be similarly expressed in breast cancer and gynaecological cancers. …”
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Human leukocyte Antigen-B*27 allele subtype prevalence and disease association of ankylosing spondylitis among south indian population by Vikram Haridas, Praveenkumar Shetty, M Nirmal Kumar, K C Vasanthakumar, Kiran Haridas, Vitthal Khode, Anil Bargale

“…The peripheral blood DNA genotyping of HLA-B27 was performed in Applied Biotechnologies 3130/3500 sequencer using SeCore HLA B Class I typing high-resolution kit from Invitrogen. …”
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Reservoir Characteristics and Its Comprehensive Evaluation of Gray Relational Analysis on the Western Sulige Gas Field, Ordos Basin, China by Xinping Liang, Qingbin Xie, Mingyu He, Quanyou Liu, Vladimir Morozov

“…By weighted gray correlation theory, the dynamic testing data—effective thickness of gas production data—is used as mother sequences. The results show that the predicted favorable areas for gas exploration and development coincide well with sedimentary and sand body distribution (e.g., point bars and central bars) in the study block; well blocks such as s372, s373, s374, and e24 could be future key development targets. …”
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SOFTWARE DEVELOPMENT AND RESEARCH FOR MACHINE LEARNING-BASED STRUCTURAL ERRORS DETECTION IN BPMN MODELS by Andrii Kopp, Dmytro Orlovskyi, Igor Gamayun, Illia Sapozhnykov

“…Business process models allow to graphically represent the sequences of events, activities, and decision points that make up business processes. …”
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