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7641
Harnessing deep learning to detect bronchiolitis obliterans syndrome from chest CT
Published 2025-01-01“…The DNN was tasked with predicting the sequence of two CT scans taken from the same BOS patient at least six months apart. …”
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7642
Phylogeographic breaks and how to find them: An empirical attempt at separating vicariance from isolation by distance in a lizard with restricted dispersal
Published 2023-08-01“…Here, we use multi-locus sequence data from a widely distributed lizard species to address these questions in an empirical setting. …”
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7643
Transforming Growth Factor-β Protects against Inflammation-Related Atherosclerosis in South African CKD Patients
Published 2018-01-01“…Functional polymorphisms in the TGF-β1 genes were genotyped using a polymerase chain reaction-sequence specific primer method and carotid intima media thickness (CIMT) was assessed by B-mode ultrasonography. …”
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7644
Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus
Published 2025-01-01“…HA2, the neck of the HA protein, and M2e, the extracellular N-terminal structural domain of the M2 protein, are conserved and effective protective antigens.In this study, the HA2 sequences were fused with three M2e copies (H9N2, H1N1 and H5N1) to the norovirus VP1 protein via the SpyTag-SpyCatcher platform to form self-assembled nanoparticles and display antigenic proteins on its surface, yielding pYL262. …”
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7645
Systematic identification of secondary bile acid production genes in global microbiome
Published 2025-01-01“…Our construction of a systematic secondary bile acid production gene catalog encompassing numerous high-quality reference sequences propelled research on bile acid metabolism in the global microbiome, holding significance for the concept of One Health. …”
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7646
Molecular Data Confirm the Occurrence of the Allochthonous <i>Gambusia holbrooki</i> (Pisces: Poeciliidae) in Sicily and the Maltese Archipelago
Published 2025-01-01“…<i>affinis</i> in Italy and Malta, we conducted extensive sampling in Sicily (Italy) and in the Maltese archipelago, aiming to verify the identity of <i>Gambusia</i> populations occurring in the study area. Based on sequences of the mitochondrial cytochrome b gene, we consistently observed the occurrence of only <i>G. holbrooki</i> in the investigated area, finding, almost exclusively, the most common haplotype known for the species in the whole invaded range (i.e., “HOL1”).…”
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7647
Tenofovir and Doravirine Are Potential Reverse-Transcriptase Analogs in Combination with the New Reverse-Transcriptase Translocation Inhibitor (Islatravir) Among Treatment-Experien...
Published 2025-01-01“…We analyzed 1170 HIV-1 sequences from patients failing first-, second-, and third-line ART using the CIRCB Antiviral Resistance Evaluation (CIRCB-CARE) database. …”
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7648
T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint pr...
Published 2023-01-01“…For both mechanisms a protein carrier/trafficker was required, since galectin-9 lacks a secretion sequence. Secreted galectin-9 pre-opsonised T cells and, following interaction with other immune checkpoint proteins, their activity was completely attenuated. …”
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7649
SSR marker-based genetic diversity and structure analyses of Camellia nitidissima var. phaeopubisperma from different populations
Published 2025-01-01“…Methods In the present study, eight simple sequence repeat (SSR) molecular markers previously screened were used to analyze the genetic diversity and structure of C. nitidissima var. phaeopubisperma natural populations from 14 growing areas in China, so as to determine the influence of environmental changes on genetic variations and provide the basis for introduction and selection of suitable growing sites of that variety. …”
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7650
Comparative evaluation of antifungal susceptibility testing methods of invasive Candida species and detection of FKS genes mutations in caspofungin intermediate and resistant isola...
Published 2025-01-01“…Hotspot (HS) regions of FKS genes were sequenced for caspofungin-intermediate and resistant isolates. …”
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7651
Giardiose et oesophagostomose nodulaire au parc national de Taï : risque zoonotique ?
Published 2016-01-01“…La technique PCR nichée a été retenue pour amplifier et séquencer les gènes de la TPI et de la Gdh à partir d’extraits d’ADN d’origine humaine et simienne de Giardia duodenalis. …”
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7652
A randomized, placebo-controlled, cross-over trial of ketamine in Rett syndrome
Published 2025-01-01“…Design This was a sequentially initiated, dose-escalating cohort, placebo-controlled, double blind, randomized sequence, cross-over study of oral ketamine in 6–12-year-old girls with RTT to evaluate short-term safety and tolerability and explore efficacy. …”
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7653
Vingt ans de pédagogie au Parc zoologique et botanique de Mulhouse : la place des Primates
Published 2016-01-01“…Basée sur l’observation et la théorie, l’approche pédagogique de l’itinéraire laisse une grande place à la discussion et parfois à la controverse.En vingt ans cette approche a évolué et s’appuie aujourd’hui sur les nouveaux outils de la bio-informatique pour la détermination des séquences génomiques, en particulier des Primates, qui permettent aux élèves d’établir un lien avec le programme en sciences de la vie et de la terre (terminale S). …”
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7654
Flexible and wireless metasurface coils for knee and elbow MRI
Published 2025-01-01“…Methods Knee and elbow MRI routine sequences were applied at 1.5 T, implementing four coil scenarios: (1) 15-channel transmit/receive knee coil; (2) four-channel multipurpose coil (flex coil); (3) MC + spine coil; and (4) MC + multipurpose coil. …”
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7655
Penerapan Metode Weighted Product untuk Seleksi Kelulusan Santri pada Sistem Informasi Wisuda Taman Pendidikan Al-Quran (TPA) Universitas Darussalam Gontor
Published 2021-03-01“…Testing using the black-box produces expected system paths and sequences without any errors. Testing the system by distributing questionnaires using a Likert scale provides an overall average value of 4.47 with a "high" satisfaction range. …”
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7656
Genome skimming provides evidence to accept two new genera (Apiaceae) separated from the Peucedanum s.l.
Published 2025-01-01“…Therefore, we conducted a comprehensive taxonomic revision of taxa within the polyphyletic Peucedanum s.l. genus in this study.MethodsWe used two molecular datasets (103 plastomes and 43 nrDNA sequences) generated by genome skimming to reconstructed a reliable phylogenetic framework with high support and resolution. …”
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7657
AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist
Published 2025-01-01“…By leveraging BMCA, the model effectively integrates structural and sequence-level information, ensuring a precise representation of molecular interactions. …”
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7658
Longitudinal genetic studies of cognitive characteristics
Published 2020-03-01“…The content, quantity and arrangement of transposable elements in human genome, which do not affect changes in nucleotide sequences of protein encoding genes, but affect their expression, can be transmitted to the next generation.…”
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7659
Exploring anticancer, antioxidant, and antimicrobial potential of Aspergillus flavus, a fungal endophyte isolated from Dillenia indica leaf callus
Published 2025-02-01“…Previously deposited sequences in the Gene bank were used for the identification and making of phylogenetic tree. …”
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7660
Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus
Published 2025-01-01“…The cDNA of mosquitoes was amplified and sequenced for four fragments of vgsc gene. The kdr L1014F mutation and the haplotype of the CYP9M10 gene were detected in survivor and dead mosquitoes after exposure to the deltamethrin WHO test paper. …”
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