Effects of diesel exhaust inhalation on cognitive performance in human volunteers: A randomized controlled crossover study by Jason Curran, A.J. Hirsch Allen, Christopher F. Rider, Robin Shutt, Chris Carlsten

“…Results: Following screening, 15 volunteers were randomized to receive FA followed by DE and 14 volunteers were randomized to receive the exposures in the reverse sequence. A total of 28 volunteers contributed to the final analysis. …”
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Multiple Controls on the Accumulation of Organic-Rich Sediments in the Besa River Formation of Liard Basin, British Columbia, Canada by Jiyoung Choi, Hyun Suk Lee, Yuri Kim, Omid H. Ardakani, Sung Kyung Hong

“…The Late Devonian Besa River Formation is an organic-rich shale sequence in Liard Basin, northeastern British Columbia, Canada, with significant natural gas reserves. …”
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Enabling regulatory policy globally will promote realization of the potential of animal biotechnology by Eric Hallerman, Justin Bredlau, Luiz Sergio A. Camargo, Maria Lucia Zaidan Dagli, Margaret Karembu, Daniel Kovich, Anne Ndanu Muia, Mariana L. Murrone, Pedro Jesus Rocha-Salavarrieta, Rhodora Romero-Aldemita, Mark Tizard, Mark Walton, Diane Wray-Cahen

“…The advent of genome editing techniques has revolutionized the scientific approach to introducing changes into DNA sequences and how biotechnology can be used to enhance agricultural breeding. …”
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Le Bonobo : Origine des HTLV mais pas du VIH by Steve Ahuka‑Mundeke, Florian Liegeois, Valentin Mbenzo, Valentin Omasombo, Ahidjo Ayouba, Octavie Lunguya, Bila‑Isia Inogwabini, Jean‑Jacques Muyembe, Eric Delaporte, Martine Peeters

“…L'infection STLV a été recherchée en utilisant des amorces spécifiques universelles du gène tax (200pb) ainsi que des LTR (450bp), suivis par les analyses phylogénétiques des séquences obtenues en utilisant la méthode de maximum de vraisemblance. …”
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Dynamic changes in the gastrointestinal microbial communities of Gangba sheep and analysis of their functions in plant biomass degradation at high altitude by Xiaozhen Liu, He Ding, Xiaoxue Zhang, Na Ta, Jinmei Zhao, Qian Zhang, Huiyun Liu, Mengjiao Sun, Xiaoqing Zhang

“…The different microbial associations among the groups were revealed by co-occurrence networks based on the amplicon sequence variants (ASVs). Moreover, a Gangba sheep gastrointestinal microbial genomic catalogue was constructed for the first time, including 1146 metagenome-assembled genomes (MAGs) with completeness > 50% and contamination < 10%, among which, 504 bacterial and 15 archaeal MAGs were of high quality with completeness > 80% and contamination < 10%. …”
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Carboplatin-resistance-related DNA damage repair prognostic gene signature and its association with immune infiltration in breast cancer by Shuwen Dong, Anqi Li, Ruixin Pan, Jin Hong, Zheng Wang, Kunwei Shen

“…This study aimed to identify the DDR genes involved in carboplatin resistance and to elucidate their effects on prognosis, immune infiltration, and drug sensitivity in breast cancer patients.MethodsA 3D-culture model resistant to carboplatin was constructed and sequenced. Co-expressed DDR genes were analyzed to develop a predictive model. …”
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TaWI12 may be involved in pistillody and leaf cracking in wheat by Yuhuan Guo, Yan Zhang, Yuhao Li, Yichao Wu, Mingli Liao, Zhengsong Peng, Zaijun Yang, Yonghong Zhou

“…The phylogenetic tree revealed a high degree of homology between the protein sequences of TaWI12 and the wound-induced proteins of Hordeum vulgare (KAI4994568) and Aegilops tauschii (XP_020196548). …”
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Development of a stable eukaryotic strain producing fully human monoclonal antibody on the basis of the human antibody against ectromelia virus by A. L. Matveev, Ya. A. Khlusevich, I. K. Baykov, I. V.  Babkin, E. P. Goncharova, V. V. Morozova, N. V. Tikunova

“…Notably, DNA of the plasmid pCDNA5/FRT­DHFR­CH­CL was organized in such a way that the restriction sites for rapid cloning of DNA fragments encoding the variable domains of heavy and light chains were inserted upstream of the sequences encoding constant domains of the heavy and light chains of the antibody. …”
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Evolutionary and functional divergence of Sfx, a plasmid-encoded H-NS homolog, underlies the regulation of IncX plasmid conjugation by Avril Wang, Martha Cordova, William Wiley Navarre

“…Recent bioinformatic analyses have revealed that plasmid-encoded H-NS homologs are widespread and exhibit high sequence diversity. However, the functional roles of most of these homologs and the selective forces driving their phylogenetic diversification remain unclear. …”
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富硒生物活性肽的制备、生物活性及构效关系研究进展 "Progress on the preparation, bioactivity and structure-activity relationship of selenium-enriched bioactive peptides"... by 侯春艳，杨趁仙 HOU Chunyan, YANG Chenxian

“…The bioactivities of selenium-enriched bioactive peptides are the results of the joint action of selenium and peptides, which are closely related to the sequence, spatial structure and interaction force of amino acids, but their structure-activity relationships need to be further studied. …”
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Cost-Benefit Analysis of Genetic Testing as a Prenatal Diagnostic Tool for Thalassemia: A Single-Center Study From Central Thailand by Malasai K, Jittikoon J, Udomsinprasert W, Talungchit P, Youngkong S, Sangroongruangsri S, Mahasirimongkol S, Chaikledkaew U

“…Kwandao Malasai,1,2 Jiraphun Jittikoon,3 Wanvisa Udomsinprasert,3 Pattarawalai Talungchit,4,5 Sitaporn Youngkong,5,6 Sermsiri Sangroongruangsri,6 Surakameth Mahasirimongkol,7 Usa Chaikledkaew5,6 1Social, Economic and Administrative Pharmacy (SEAP) Graduate Program, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 2Social Pharmacy Research Unit, Faculty of Pharmacy, Mahasarakham University, Maha Sarakham, Thailand; 3Department of Biochemistry, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 4Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; 5Mahidol University Health Technology Assessment (MUHTA) Graduate Program, Mahidol University, Bangkok, Thailand; 6Social and Administrative Pharmacy Division, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 7Information and Communication Technology Center, Office of the Permanent Secretary, Ministry of Public Health, Nonthaburi, ThailandCorrespondence: Usa Chaikledkaew, Social and Administrative Pharmacy Division, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayudhaya Road, Rachathewi, Phayathai, Bangkok, 10400, Thailand, Email usa.chi@mahidol.ac.thPurpose: This study aimed to evaluate the costs and benefits of genetic testing, specifically mutation analysis and prenatal diagnostic testing, for the confirmation of thalassemia in at-risk pregnancies in Thailand, providing crucial insights to inform public health policy decision-making.Patients and Methods: We analyzed the costs and benefits of following standard screening guidelines, which included a sequence of tests such as mean corpuscular volume (MCV)/mean corpuscular hemoglobin (MCH) with dichlorophenol indophenol precipitation (DCIP), hemoglobin (Hb) typing, genetic testing, and amniocentesis. …”
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An MRI radiomics model for predicting a prostate-specific antigen response following abiraterone treatment in patients with metastatic castration-resistant prostate cancer by Yi Wu, Xiang Liu, Shaoxian Chen, Fen Fang, Feng Shi, Yuwei Xia, Zehong Yang, Daiying Lin

“…Univariate and multivariate analyses were performed using Cox regression to identify significant predictors of the efficacy of abiraterone treatment in patients with mCRPC.ResultsThe integrated model was constructed from seven radiomics features extracted from the T2WI, DWI, and ADC sequence images of the training data. This model demonstrated the highest AUC in both the training and validation cohorts, with values of 0.889 (95% CI, 0.764-0.961) and 0.875 (95% CI, 0.564-0.991). …”
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On the Biosynthesis of Bioactive Tryptamines in Black Cohosh (<i>Actaea racemosa</i> L.) by Martin J. Spiering, James F. Parsons, Edward Eisenstein

“…Two <i>T5H-like</i> sequences were identified in <i>A. racemose,</i> but their co-expression with the high-activity TDCs in yeast did not result in serotonin production. …”
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Nutrient cycling characteristics along a chronosequence of forest primary succession in the Hailuogou Glacier retreat area, eastern Tibetan Plateau by Danli Yang, Ji Luo, Shumiao Shu, Yan Hu, Hongsong Tang, Xuemei Li

“…Background The Hailuogou Glacier has been continuously retreating since the end of the Little Ice Age, resulting in a 125-year soil chronosequence and a complete primary forest succession sequence. Nutrient cycling and utilization are the foundation to forest succession processes and dynamic changes, directly influencing the structure and stability of ecosystems. …”
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Priority effects, nutrition and milk glycan-metabolic potential drive Bifidobacterium longum subspecies dynamics in the infant gut microbiome by Nicholas Pucci, Joanne Ujčič-Voortman, Arnoud P. Verhoeff, Daniel R. Mende

“…Methodology We analyzed newly sequenced gut microbiome samples of mother-infant pairs from the Amsterdam Infant Microbiome Study (AIMS) and four publicly available datasets to identify important environmental and bifidobacterial features associated with the colonization success and succession outcomes of B. longum subspecies. …”
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Mathematical modelling and phylodynamics for the study of dog rabies dynamics and control: A scoping review. by Maylis Layan, Simon Dellicour, Guy Baele, Simon Cauchemez, Hervé Bourhy

“…Future integrative approaches that use phylodynamic analyses and mechanistic models within a single framework could take full advantage of not only viral sequences but also additional epidemiological information as well as dog ecology data to refine our understanding of rabies spread and control. …”
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Phage vB_Kpn_HF0522: Isolation, Characterization, and Therapeutic Potential in Combatting K1 Klebsiella pneumoniae Infections by Yan T, Wang Q, Ma C, Teng X, Gong Z, Chu W, Zhou Q, Liu Z

“…Analysis of vB_Kpn_HF0522 characteristics, including optimal multiplicity of infection (MOI), one-step growth curve, host range, stability in different environments, and adsorption capacity. The phage genomic sequence was analyzed to explore evolutionary relationships. …”
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Evaluation of Hydrocarbon Generation Using Structural and Thermal Modeling in the Thrust Belt of Kuqa Foreland Basin, NW China by Chengfu Lyu, Xixin Wang, Xuesong Lu, Qianshan Zhou, Ying Zhang, Zhaotong Sun, Liming Xiao, Xin Liu

“…In contrast, the source rock was immature at an early stage and subsequently grew into a low mature-mature stage in the Baicheng Sag–South slope belt. The time sequence of the thermal evolution of source rocks and structural trap formation and their matching determines the different accumulation processes and oil and gas compositions in the different structural belts of the Kuqa foreland basin. …”
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5′-UTR allelic variants and expression of the lycopene-ɛ-cyclase <i>LCYE</i> gene in maize (<i>Zea mays</i> L.) inbred lines of Russian selection by D. Kh. Arkhestova, B. R. Shomakhov, A. V. Shchennikova, E. Z. Kochieva

“…The parallel β,ε-branch is triggered by lycopene-ε-cyclase LCYE, a low expression of which leads to an increase in provitamin A content and is associated with the variability    of the 5’-UTR gene regulatory sequence. In this study, we screened a collection of 165 maize inbred lines of Russian selection for 5’-UTR LCYE allelic variants, as well as searched for the dependence of LCYE expression levels on the 5’-UTR allelic variant in the leaves of 14 collection lines. 165 lines analyzed were divided into three groups carrying alleles A2 (64 lines), A5 (31) and A6 (70), respectively. …”
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Reflexive Methods of Knowledge in Educational Activities: Phenomenological Hermeneutics by T. N. Korneenko

“…In phenomenological approach, the student is regarded as a live, constantly changing character of own personal formation and development; knowledge process is considered as the sequence of acts of understanding and its judgment in close teacher-student interaction. …”
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