CircXYLT1 suppresses oxidative stress and promotes vascular remodeling in aging mice carotid artery injury model of atherosclerosis via PTBP1 by Gang Li, Donghui Li, Yajing Li, Bingqi Liu

“…This study explores the role of CircXYLT1 in regulating oxidative stress and vascular remodeling in age-related vascular diseases. RNA sequencing revealed a significant upregulation of CircXYLT1 in the vascular tissues of aged mice, highlighting its potential role in age-related vascular diseases. …”
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Comprehensive Analysis of Gene Signatures of m6ARNA Methylation Regulators in Lung Adenocarcinoma and Development of a Risk Scoring System by Chundi Gao, Huayao Li, Wenzhe Ma, Qiming Zhang, Cun Liu, Lijuan Liu, Jing Zhuang, Changgang Sun

“…We systematically studied correlations among important M6A methylation regulators, tumor mutational burden (TMB), and immune infiltration in clinical and sequencing data from the LUAD cohort of the cancer genome map (TCGA). …”
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Microcephalic osteodysplastic primordial dwarfism type II in four Indian children with PCNT variants by Amit Singh, Mahak Garg, Mohammed Shariq, Preeti Khetarpal, Inusha Panigrahi

“…Case presentation Four patients of Indian origin with growth deficiency and additional clinical features of MOPDII were recruited from a tertiary health care center and whole exome sequencing was performed on blood samples from these patients. …”
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Novel relatives of Mecsek Mountains mammarenavirus (family Arenaviridae) in hedgehogs living in different sampling areas in Hungary by Károly Takáts, Péter Pankovics, Benigna Balázs, Ákos Boros, Róbert Mátics, Gábor Reuter

“…The NP protein exhibited 86–97% aa sequence identity compared to the corresponding protein of MEMV. …”
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A database on genes increasing resistance of wheat and relative species against pathogenic fungi by O. G. Smirnova, A. V. Kochetov

“…During the last years many wheat resistance genes were identified. However, the sequencing of the Triticum aestivum L. genome is still going on and the nucleotide sequences of most resistance genes are not yet known. …”
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The Complete Chloroplast Genome of Erythrina variegata L. (Papilionoideae, Fabaceae) by Nguyen Nhat Nam, Nguyen Ngoc Trai, Nguyen Phuong Thuy, Le Quoc Duy, Pham Nguyen Tuong Van, Tan Tai Nguyen, Hoang Dang Khoa Do

“…In this study, the complete chloroplast genome of E. variegata was sequenced and characterized using Illumina sequencing platform. …”
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Destabilization of mutualistic interactions shapes the early heat stress response of the coral holobiont by Emma Marangon, Nils Rädecker, Joan Y. Q. Li, Marko Terzin, Patrick Buerger, Nicole S. Webster, David G. Bourne, Patrick W. Laffy

“…Results In a 2-month manipulative experiment, we exposed the coral Porites lutea to gradually increasing temperatures corresponding to 0–8 degree heating weeks (DHW) and assessed the response of the coral holobiont using coral and Symbiodiniaceae transcriptomics, microbial 16S rRNA gene sequencing and physiological measurements. From early stages of heat stress (< 1 DHW), the increase in metabolic turnover shifted the holobiont to a net heterotrophic state in which algal-derived nutrients were insufficient to meet host energy demands, resulting in reduced holobiont performance at 1 DHW. …”
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Phylogenomic and mitogenomic data can accelerate inventorying of tropical beetles during the current biodiversity crisis by Michal Motyka, Dominik Kusy, Matej Bocek, Renata Bilkova, Ladislav Bocak

“…The outcome would be a scaffold for the incorporation of further data from environmental sequencing and ecological studies. The database of sequences could set a benchmark for the spatiotemporal evaluation of biodiversity, would support evidence-based conservation planning, and would provide a robust framework for systematic, biogeographic, and evolutionary studies.…”
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KRAS Mutation in Serous Borderline Tumor of the Testis: Report of a Case and Review of the Literature by Sarah Bouri, Jean-Christophe Noël, Xavier Catteau, Walid Al Hajj Obeid, Ilyas Svistakov, Thierry Roumeguère, Nicky D’Haene, Sandrine Rorive

“…Mutation testing using next-generation sequencing showed a Q61K KRAS gene mutation. To the best of our knowledge, this is the second case report of a serous borderline tumor of the testis with a Q61K KRAS gene mutation.…”
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Genome-Wide Analysis and Expression Profiling of Watermelon <i>VQ</i> Motif-Containing Genes Under Abiotic and Biotic Stresses by Yanjun He, Jia Shen, Xinyang Xu, Weisong Shou

“…Quantitative real-time PCR (qRT-PCR) analysis indicated that the majority of <i>ClVQ</i> genes were specifically or preferentially expressed in certain tissues or organs, especially in the male flower. Analyses of RNA-sequencing data under osmotic, cold, and drought stresses and <i>Cucumber green mottle mosaic virus</i> (CGMMV) infection revealed that the majority of <i>ClVQ</i> genes, especially those from subfamily IV, were responsive to these stresses. …”
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Reverse-engineering the FLT3-PI3K/AKT axis to enhance TILs function and improve prognosis in ovarian and cervical cancers by Feng Hao, Zhang Yan, Luo Shen, Wang Hui, Qiu Ling, Yang Xiaoyu, Jiang Hua

“…Methods We integrated single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) to explore immune regulation in OC and CC, focusing on the PI3K/AKT pathway and FLT3 as key modulators. …”
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Loss of YTHDC1 m6A reading function promotes invasiveness in urothelial carcinoma of the bladder by Jinyun Xu, Jonas Koch, Claudia Schmidt, Malin Nientiedt, Manuel Neuberger, Philipp Erben, Maurice Stephan Michel, Manuel Rodríguez-Paredes, Frank Lyko

“…Integrative analysis of multimodal sequencing datasets provided detailed insights into the molecular mechanisms mediating YTHDC1-dependent phenotypes and identified SMAD6 as a key transcript involved in the invasiveness of urothelial carcinoma of the bladder. …”
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Nucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and Monocytes by K. R. Higgins, W. Kovacevic, L. Stokes

“…With such variability in response we looked for single nucleotide polymorphisms in P2RY2 that could affect the functional response. Sequencing of P2RY2 from THP-1 cells revealed the presence of a single nucleotide polymorphism altering amino acid 312 from arginine to serine (rs3741156). …”
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Novel bacteriophages targeting wheat phyllosphere bacteria carry DNA modifications and single-strand breaks by Peter Erdmann Dougherty, Maja Schmidt Pedersen, Laura Milena Forero-Junco, Alexander Byth Carstens, Jos M. Raaijmakers, Leise Riber, Lars Hestbjerg Hansen

“…Finally, we also search the Sequence Read Archive for similar phages in public metagenomes. …”
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Genomic and Computational Analysis of Novel SNPs in TNP1 Gene Promoter Region of Bos indicus Breeding Bulls by Kashif Hameed Anjum, Asif Nadeem, Maryam Javed, Hafiz Ishfaq Ahmad, Amjad Riaz, Wasim Shehzad, Jahanzaib Azhar, Muhammad Fahad Bhutta

“…DNA samples were sequenced to identify novel single nucleotide polymorphisms (SNPs) in the TNP1 gene. …”
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Contribution of m5C RNA Modification-Related Genes to Prognosis and Immunotherapy Prediction in Patients with Ovarian Cancer by Yibin Liu, Shouze Liu, Lu Yan, Qianqian Zhang, Wenhua Liu, Xianghua Huang, Shikai Liu

“…Methylated-RNA immunoprecipitation sequencing helped us to identify candidate genes related to m5C RNA modification at first. …”
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Identification and Characterization of Wheat Streak Mosaic Virus Isolates in Wheat-Growing Areas in Brazil by Talita Bernardon Mar, Douglas Lau, Jurema Schons, Paulo Roberto Valle da Silva Pereira, Alan Johnny Carminatti

“…Six isolates of WSMV were obtained and characterized by sequencing. Two of them had their host range determined. …”
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Screening and identification of purine degrading Lactobacillus fermentum 9-4 from Chinese fermented rice-flour noodles by Lianghua Lu, Tiantian Liu, Xiaoling Liu, Chenghua Wang

“…A new lactic acid bacteria strain designated as Lactobacillus fermentum 9-4 was screened out from 10 Shengzhamifen samples by a comprehensive method integrating agar plate selection, in vitro purine-metabolizing enzymatic activities of xanthine oxidase and urate oxidase, 16S rRNA gene sequencing and identification. The resting cells of L. fermentum 9-4 showed the maximum degradation rates of inosine and guanosine by respective 2.13 × 10−3 and 2.78 × 10−3 g/(L·min), and the highest assimilation ratio of guanosine by (55.93 ± 3.12)%, which are improvements over LAB strains characterized previously. …”
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Fecal shedding level of Haemonchus contortus is associated with gastrointestinal bacterial microbial composition in naturally infected sheep by Jeferson Vidart Ramos, Verônica Rocha Merched, Laura Dias da Silva Ribeiro, Guilherme Neves Lima Rattmann, Renan Eugênio Araújo Piraine, Fabio Pereira Leivas Leite

“…Stool samples were collected monthly for egg counts (EPG), and 16S rRNA gene sequencing was performed on five animals from each group. …”
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VCAM-1 Promotes Angiogenesis of Bone Marrow Mesenchymal Stem Cells Derived from Patients with Trauma-Induced Osteonecrosis of the Femoral Head by Regulating the Apelin/CCN2 Pathway by Yiming Shao, Lei Sun, Baodong Ma, Ranran Jin, Yueyao Ban, Ruibo Li, Jianfa Wang, Hongkai Lian, Han Yue

“…We further performed mRNA transcriptome sequencing to explore the mechanisms by which VCAM-1 promotes angiogenesis. …”
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