A very low carbohydrate diet improved metabolic profile in congenital generalized lipodystrophy type 4 by Sayantan Chakraborty, Subhankar Roy, Debaditya Das, Sayantani Chatterjee, Pranab Kumar Sahana, Satinath Mukhopadhyay

“…A switch to a very low carbohydrate (30% of total calorie) diet led to a remarkable improvement in glucose and lipid profiles (the daily insulin requirement came down by 50% and triglyceride level came down to 600 mg/dL from 950 mg/dL). A whole-exome sequencing study confirmed congenital generalized lipodystrophy type 4. …”
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Proteomics and Its Current Application in Biomedical Area: Concise Review by Semira Gobena, Bemrew Admassu, Mebrie Zemene Kinde, Abebe Tesfaye Gessese

“…Various sophisticated techniques are employed in proteomics, including polyacrylamide gel electrophoresis, mass spectrometry analysis, NMR spectroscopy, protein microarray, X-ray crystallography, and Edman sequencing. These methods collectively contribute to the comprehensive understanding of proteins and their roles in health and disease. …”
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Functionally-informed fine-mapping identifies genetic variants linking increased CHD1L expression and HIV restriction in monocytes by Riley H. Tough, Paul J. McLaren, The International Collaboration for the Genomics of HIV

“…We assess the combined impact of these variants on CHD1L regulation using publicly available sequencing studies, and test the relationship between CHD1L expression and set-point viral load using imputed CHD1L expression from monocytes. …”
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miR-21 promotes cervical cancer by regulating NTF3 by Yishan Chen, Caiwu Su, Yuke Cai, Lina Ke, Yaxiong Huang

“…Overexpression of NTF3 inhibited cell proliferation and migration, while promoting apoptosis, as demonstrated by flow cytometry. Transcriptome sequencing and enrichment analyses (KEGG and GO) revealed NTF3’s involvement in key oncogenic pathways, including PI3K-AKT, MAPK, and calcium signaling. …”
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Evaluating the Cassandra NoSQL Database Approach for Genomic Data Persistency by Rodrigo Aniceto, Rene Xavier, Valeria Guimarães, Fernanda Hondo, Maristela Holanda, Maria Emilia Walter, Sérgio Lifschitz

“…Rapid advances in high-throughput sequencing techniques have created interesting computational challenges in bioinformatics. …”
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Population-level gut microbiome and its associations with environmental factors and metabolic disorders in Southwest China by Qianyu Qu, Qingyu Dou, Zhejun Xiang, Bin Yu, Lili Chen, Zhenxin Fan, Xing Zhao, Shujuan Yang, Peibin Zeng

“…Here, we performed metagenomic sequencing on fecal samples from the CMEC Microbiome Project in Southwest China. …”
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THE BIOTECHNOLOGICAL POTENTIAL OF THE NEW CROP, Miscanthus cv . SORANOVSKII by N. M. Slynko, T. N. Goryachkovskaya, S. V. Shekhovtsov, S. V. Bannikova, N. V. Burmakina, K. V. Starostin, A. S. Rozanov, N. N. Nechiporenko, S. G. Veprev, V. K. Shumny, N. A. Kolchanov, S. E. Peltek

“…On the base of phenotyping and DNA sequencing, the new crop was identified as Miscanthus sacchariflorus. …”
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Promyelocytic Leukemia with No Retinoic Acid Receptor Alpha Abnormality but with RUNX1T1 Insertion to Chromosome 7q: A Classification and Management Dilemma by Kathleen Overholt, Terri L. Guinipero, Nyla A. Heerema, Michael R. Loken, Samir B. Kahwash

“…The only cytogenetic abnormality found was a small insertion in 7q, and three copies of RUNX1T1. Gene sequencing results became available after initiating therapy but were not informative. …”
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Genetic Basis for Variation of Metalloproteinase-Associated Biochemical Activity in Venom of the Mojave Rattlesnake (Crotalus scutulatus scutulatus) by Ruben K. Dagda, Sardar Gasanov, Ysidro De La OIII, Eppie D. Rael, Carl S. Lieb

“…Overall, based on genomic sequencing and biochemical data, we classified Mojave rattlesnake venom into four distinct groups of metalloproteinases. …”
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<i>Salmonella</i> bacteria in farm animal feeds. Review by N. B. Shadrova, O. V. Pruntova, G. S. Skitovich, О. А. Akulich

“…A research into antimicrobial resistance of Salmonella isolates demonstrated resistance to such medicinalproducts as ceftriaxone, carbopenem and imipenem; and full genome sequencing showed at least one antibiotic resistance gene in 40% of Salmonella isolates detected at pig feed production plants.…”
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Taming large-scale genomic analyses via sparsified genomics by Mohammed Alser, Julien Eudine, Onur Mutlu

“…Abstract Searching for similar genomic sequences is an essential and fundamental step in biomedical research. …”
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Diversity of 4-Chloro-2-nitrophenol-Degrading Bacteria in a Waste Water Sample by Pankaj Kumar Arora, Alok Srivastava, Vijay Pal Singh

“…These eighteen 4C2NP-decolorizing strains have been identified as members of four different genera, including Bacillus, Paenibacillus, Pseudomonas, and Leuconostoc based on the 16S rRNA gene sequencing and phylogenetic analysis. Most of the bacteria (10) belonged to the genus Bacillus and contributed 56% of the total 4C2NP-degrading bacteria, whereas the members of genera Paenibacillus and Pseudomonas represented 22% and 17%, respectively, of total 4C2NP-degrading isolates. …”
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Transcriptome size matters for single-cell RNA-seq normalization and bulk deconvolution by Songjian Lu, Jiyuan Yang, Lei Yan, Jingjing Liu, Judy Jiaru Wang, Rhea Jain, Jiyang Yu

“…Abstract The variation of transcriptome size across cell types significantly impacts single-cell RNA sequencing (scRNA-seq) data normalization and bulk RNA-seq cellular deconvolution, yet this intrinsic feature is often overlooked. …”
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Distinct fungal communities associated with different organs of the mangrove Sonneratia alba in the Malay Peninsula by Nicole Li Ying Lee, Danwei Huang, Zheng Bin Randolph Quek, Jen Nie Lee, Benjamin J. Wainwright

“…We are able to assign taxonomy to the majority of sequences from leaves and fruits, but a much larger portion of the sequences recovered from pneumatophores and sediment samples could not be identified. …”
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NGS Analysis of Clonality and Minimal Residual Disease in a Patient with Concurrent Richter’s Transformation and CLL/SLL by Shrihari S. Kadkol, Joshua Bland, Ashley Kavanaugh, Hongyu Ni, Vijeyaluxmi Nehru, David Peace

“…More recently, next-generation sequencing (NGS) has been used to detect clonality in B-cell lymphomas because of the exponential amount of information that is obtained beyond just detecting a clonal population. …”
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Prevalence and Molecular Epidemiological Data on Dirofilaria immitis in Dogs from Northeastern States of India by Sonjoy Kumar Borthakur, Dilip Kumar Deka, Saidul Islam, Dilip Kumar Sarma, Prabhat Chandra Sarmah

“…Diagnostic methods applied were microscopy (wet film and Knott’s concentration technique), immunological test (Ag ELISA by SNAP 4Dx ELISA kit), and molecular tools (polymerase chain reaction and sequencing), which evidenced 11.38, 18.03, and 13.93% of positive animals, respectively. …”
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Homology Modeling and Expression of Recombinant NS5-RdRp Based on the Indonesian Local Strain of Dengue Virus for Anti-Dengue Drug Development by Toto Subroto, Ade Rizqi Ridwan Firdaus, Shinta Kusumawardani, Taufik Ramdani Tohari, Theresia Adventina Nababan, Wulan Pertiwi, Muhammad Fadhlillah, Sri Agung Fitri Kusuma, Yaya Rukayadi

“…Then, followed by the extraction and purification of the RdRp amplicon for gene sequencing. The resulting RdRp gene sequences are translated into amino acid sequences, which are then used for protein modeling and the construction of a recombinant plasmid for RdRp protein expression. …”
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The mechanisms of fiber flax adaptation to high soil acidity (a review) by N. V. Kishlyan, N. V. Melnikova, T. A. Rozhmina

“…Using high-through put sequencing and quantitative PCR, a change in the expression of genes and microRNAs in flax plants was revealed in response to the toxic effect of aluminum ions. …”
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Characteristics of lower respiratory microbiota in children’s refractory Mycoplasma pneumoniae pneumonia pre- and post-COVID-19 era by Zhimin Xi, Jinglong Chen, Libo Wang, Aizhen Lu

“…The characteristics of the clinical findings were examined, and the LRT microbiota was analyzed by metagenomic next generation sequencing.ResultsThe ratio of consolidate, atelectasis, lung necrosis, and erythema multiforme in Y2023 group was significantly higher than that in Y2019 (P&lt;0.05). …”
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Artificial Neural Network-Based Identification of Associations between UCP2 and UCP3 Gene Polymorphisms and Meat Quantity Traits by Javed Ahmed Ujjan, Sapna Waheed Memon, Majeeda Ruk, Zuneera Akram, Allahwadhayo Ghoto, Betty Nokobi Dugbakie

“…Using polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and sequencing, the results of this study indicated 07 variations in the exon 4 region of the UCP2 gene and 03 variants in the exon 3 area of the UCP3 gene among 215 indigenous cow breeds. …”
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