Transition from Intravenous Epoprostenol to Oral or Subcutaneous Therapy in Pulmonary Arterial Hypertension: A Retrospective Case Series and Systematic Literature Review by Kirily Park, David Ostrow, Robert D Levy, John Swiston

“…This medication has multiple side effects, and sudden discontinuation is potentially associated with severe sequelae. Several recent case series have described the transition from intravenous to newer oral or subcutaneous therapies. …”
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A Singleton Infant with Bilateral Renal Agenesis and Normal Pulmonary Function by Lovya George, Winston Manimtim, Jotishna Sharma

“…Bilateral renal agenesis leads to anhydramnios and other sequelae including pulmonary hypoplasia. There have been rare case reports of normal pulmonary function in the presence of bilateral renal agenesis in monoamniotic discordant twins, but this has never been reported in a singleton pregnancy. …”
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Unexplained Neonatal Cardiorespiratory Collapse at Five Minutes of Age by Sona Zaleta, Sarah Miller, Prashant Kumar

“…The case serves as a timely reminder that cord gas analysis is recommended in all cases of potential fetal compromise and that Apgar scores should be used with caution as a predictor of neurological sequelae.…”
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Idiopathic Thrombosis of the Inferior Vena Cava and Bilateral Femoral Veins in an Otherwise Healthy Male Soldier by Sarah Gordon, Tamie Kerns, William Londeree, Brian Ching

“…Prompt recognition is necessary to minimize long-term sequelae.…”
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Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding by Srinath Sundararajan, Beth Braunhut, Frederick Ahmann, Amit Agarwal

“…This led to multiple adverse sequelae including ischemic stroke and bowel perforation.…”
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A Socio Behavioural Perspective for Understanding and Managing Behaviour Problems in Children with Epilepsy by C. A. Cull, S. W. Brown

“…In addition, the negative psychosocial sequelae of a diagnosis of epilepsy can result in conditions which are likely to foster the development of inappropriate behaviours. …”
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Functional Treatment of a Child with Extracapsular Mandibular Fracture by Diana Cassi, Marisabel Magnifico, Chiara Di Blasio, Mauro Gandolfini, Alberto Di Blasio

“…The management of condylar fractures is still controversial, especially when fractures occur in children: if overlooked or inappropriately treated, these lesions may lead to severe sequelae, both cosmetic and functional. The therapy must be careful because severe long-term complications can occur. …”
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Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia by O. E. O'Sullivan, D. Crosby, B. Byrne, C. Regan

“…As the disease is progressive all cases will develop portal fibrosis, cirrhosis, and portal hypertension with the sequelae of varices, jaundice, and eventually liver failure requiring a transplant. …”
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Ventricular Fibrillation following Varicella Zoster Myocarditis by Adam Ioannou, Irene Tsappa, Sofia Metaxa, Constantinos G. Missouris

“…This case demonstrates the life-threatening long-term sequelae of VZV myocarditis in adults. We suggest that VZV myocarditis should be considered in all patients who present with a syncopal event after VZV infection. …”
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Bilateral Renal Cortical Necrosis in Meningococcal Meningitis by C. Kennedy, S. Khilji, A. Dorman, J. Walshe

“…The clinical picture evolves rapidly and, if treatment is delayed, can result in a variety of long-term sequelae, including death. Acute kidney injury in the setting of bacterial meningitis usually results from hypotension and volume depletion and resolves with appropriate treatment. …”
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Allergen-Induced Asthma by Donald W Cockcroft

“…The associated allergen-induced airway hyper-responsiveness (1977) and allergen-induced airway inflammation (1985) indicate that these late sequelae are important in the mechanism of allergen-induced asthma. …”
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Cardiac Sarcoidosis as an Uncommon Etiology for Posterior Circulation Stroke Presenting with Alexia without Agraphia by Mohankumar Kurukumbi, Lauren Gardiner, Shevani Sahai, John W. Cochran

“…Cardiogenic stroke is an uncommon manifestation of cardiac sarcoidosis, and given the disabling nature of these sequelae, the importance of early diagnosis and prevention with anticoagulation is crucial to prevent morbidity and mortality.…”
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Propylene Glycol Toxicity in Adolescent with Refractory Myoclonic Status Epilepticus by Kara A. Bjur, Bryan C. Cannon, Anthony L. Fine, Matthew J. Ritter, Kerry E. Schueler, Michael E. Nemergut

“…We describe a case and the physiologic sequelae of propylene glycol toxicity manifested in a critically ill adolescent male with refractory myoclonic status epilepticus aggressively treated with multiple PG-containing medications (lorazepam, phenobarbital, and pentobarbital)—all within accepted dosing guidelines and a total daily PG exposure previously recognized to be safe. …”
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A case of vaccine‐associated myocarditis following pneumococcal immunization leading to acute mitral regurgitation by Hiroyuki Yamamoto, Marie Takahashi, Jun Isogai

“…Abstract Vaccine‐associated myocarditis (VAM) is a rare entity but can result in potentially serious sequelae if left untreated. However, the mechanisms of the complications of VAM and its treatment remain unclear. …”
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Pseudomonas aeruginosa Septic Arthritis and Osteomyelitis after Closed Reduction and Percutaneous Pinning of a Supracondylar Humerus Fracture: A Case Report and Review of the Liter... by Adam M. Wegner, John C. Wuellner, Brian M. Haus

“…We describe the treatment course for this patient, followed by the sequelae of posterolateral rotary instability. This case not only confirms that patients can get Pseudomonas infections if they get their cast wet but also stresses the importance of patient communication and compliance in preventing unfortunate complications.…”
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Immunopathological Basis of Virus-induced Myocarditis by Reinhard Maier, Philippe Krebs, Burkhard Ludewig

“…CVB3-induced acute myocarditis is most likely the consequence of direct virus-induced myocyte damage, whereas chronic CVB3 infection-associated heart disease is dominated by its immunopathological sequelae. Bona fide autoimmunity, for example, directed against cardiac myosin, may favor chronic destructive immune damage in the heart muscle and thereby promote the development of DCM. …”
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Cardiopulmonary Failure Requiring ECMO Bypass Resulting from Leukemia Cell Lysis in a Patient with Childhood Acute Myelomonocytic Leukemia by Michael Huang, Erin Owen, Scott Myers, Ashok Raj

“…Upon recovery, the patient went on to complete therapy and remains in remission without permanent neurologic or cardiac sequelae. Conclusion. Cytokine release syndrome from rapid cell lysis was the likely cause as infectious workup failed to reveal a definitive etiology and drug hypersensitivity testing to the chemotherapy agents was negative.…”
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Multifocal Gastric Neoplasia after Recurrent Laser Therapy for the Watermelon Stomach by Charles N Bernstein, Norman Pettigrew, Kenneth K Wang, Howard Greenberg, Jeremy Lipschitz

“…Repeated laser therapy has become an accepted therapeutic approach in the treatment of watermelon stomach, and to date no important negative sequelae have been reported. The case of a patient who underwent repeated sessions of neodymium: yttrium aluminum garnet (Nd:YAG) laser therapy over a five-year period for the treatment of the watermelon stomach is presented. …”
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Cholecystectomy of an Intrahepatic Gallbladder in an Ectopic Pelvic Liver: A Case Report and Review of the Literature by Rachel Mathis, Joshua Stodghill, Timothy Shaver, George Younan

“…Intrahepatic gallbladder is another rare condition predisposing patients to cholelithiasis and its sequelae. We describe a cholecystectomy in a patient with an intrahepatic gallbladder in a pelvic ectopic liver. …”
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Therapeutic Potential of Retinoid X Receptor Modulators for the Treatment of the Metabolic Syndrome by Jane A. Pinaire, Anne Reifel-Miller

“…These recent findings suggest that, with continued research efforts, RXR-specific ligands with improved pharmacological profiles may eventually be available as additional treatment options for the current epidemic of obesity, insulin resistance, type 2 diabetes, and all of the associated metabolic sequelae.…”
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