Surgical and Non-surgical Treatments in Pleural Empyema by Sami DENİZ, Nimet AKSEL, Özer ÖZDEMİR, Görkem VAYISOĞLU ŞAHİN, Ezgi ÇİMEN ÇELİK, Mutlu Onur GÜÇSAV, Filiz GÜLDAVAL, Ahmet Emin ERBAYCU, Ahmet ÜÇVET

“…The treatment results revealed no significant difference between three groups (recovered, sequelae changes, death), except for blood neutrophil count and antibiotic duration. …”
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Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity by Roel A. van der Heijden, Martine C. Morrison, Fareeba Sheedfar, Petra Mulder, Marijke Schreurs, Pascal P. H. Hommelberg, Marten H. Hofker, Casper Schalkwijk, Robert Kleemann, Uwe J. F. Tietge, Debby P. Y. Koonen, Peter Heeringa

“…We hypothesized that their effects on attenuating obesity-induced dyslipidemia as well as the associated inflammatory sequelae especially have health-promoting potential. …”
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Prevalence and Risk Factors of Helicobacter pylori Infection among Children Aged 1 to 15 Years at Holy Innocents Children’s Hospital, Mbarara, South Western Uganda by Phoebe Aitila, Michael Mutyaba, Simon Okeny, Maurice Ndawula Kasule, Rashid Kasule, Frank Ssedyabane, Benson Okongo, Richard Onyuthi Apecu, Enoch Muwanguzi, Caesar Oyet

“…The infection is generally acquired during childhood but can remain asymptomatic, with long-term clinical sequelae including gastritis, peptic ulcer disease, and stomach cancer. …”
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Multicentre, multitime, multidimension, prospective follow-up cohort study on patients during the first wave of COVID-19 in China: a study protocol by Ming Zhang, Xuan Niu, Tonghui Liu, Chao Zheng, Huijie Yuan, Yanan Zhu, Huiping Liu, Shan Wu, Zhaoyao Luo, Jia Zhu, Danwei Hou, Tianhua Wei, Zhimin Zhu, Weipeng Huang, Weixian Bai, Xinyi Yu, Wenrui Bao

“…Emerging evidence suggests that beyond the acute phase, patients with COVID-19 may experience a wide range of postacute or long COVID sequelae. However, the mechanism and burden of COVID-19, especially long COVID, have not yet been comprehensively clarified. …”
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Peroral endoscopic myotomy with fundoplication (POEM-F) for achalasia: Systematic review and meta-analysis by Harishankar Gopakumar, Eugene Annor, Ishaan Vohra, Iman Andalib, Amy Tyberg, Avik Sarkar, Haroon Shahid, Mine Carames, Juan Carlos Carames, Giovanna Porfilio Gularte, Abed Al-Lehibi, Resheed Alkhiari, Amol Bapaye, Carlos Robles-Medranda, Michel Kahaleh

“… Background and study aims: Gastroesophageal reflux (GER) and its long-term sequelae remain a concern following peroral endoscopic myotomy (POEM). …”
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Qualitative evaluation of the Rehabilitation Exercise and psycholoGical support After COVID-19 InfectioN (REGAIN) randomised controlled trial (RCT): ‘you are not alone’ by Gordon McGregor, Susanne Finnegan, Martin Underwood, Joyce Yeung, James Mason, Peter Heine, Nigel Edwards, Julie Bruce, Kate Seers, Harbinder Kaur Sandhu, Helen Atherton, Sharisse Alleyne, Katie Booth, Ranjit Lall, Vivien P Nichols, Stuart Ennis, Scott McGuire, Rachel Potter, Jessica Smith, Chen Ji, Shilpa Patel, Henry Nwankwo, Kate Evans, Susie Hennings, Alastair Canaway, Grace Lobley, David Mcwilliams, Christina Jones, Emma Padfield, David Montgomery, Beatriz Lara, Becky Haley, Francesca Denton, Bartholomew Sheehan, Mariam Ratna, Elaine Fairbrother, Zoe Noakes, Bogdan Zutic, Lee Austin, Tom Forsyth, Anne Bush, Alan Bush, Patrick Sawdon, Jonathon Prosser, Lee Tompkins, Jonathon Guck, Danielle Hale, Juwairia Said, Georgie Ray, Rowena Williams, Gail Evans, Thillini Hettiarachchi, Abeesh Panicker

“…Framework and thematic analysis were used to analyse the findings.Setting England and Wales, UK.Participants Adults discharged from National Health Service (NHS) hospitals at least 3 months previously after COVID-19, with ongoing physical and/or mental health sequelae.Results Twenty intervention participants, 20 control participants and five practitioners were interviewed.The themes from the group support sessions were: (1) you are not alone; (2) sharing experiences and addressing worries; (3) gaining new perspectives; (4) hope for progression; (5) peer support and bonding; (6) integration of facilitation skills; (7) modified activity pacing and goal setting, and (8) giving participants structure. …”
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plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN): a protocol for a prospective diagnostic accuracy study of point-of-care testing in patients suspected of acute... by Thomas R Fanshawe, Philip J Turner, Gail N Hayward, Margaret Glogowska, Alastair D Hay, Michael Moore, Mark Lown, Christopher C Butler, Mandy Wootton, Mark H Wilcox, Jane Freeman, Nicola Kenealy, Valerie Tate, Owain Llion, Rebecca Lowe

“…Introduction Acute uncomplicated urinary tract infection (UTI) is a common condition with potentially serious sequelae that is mostly diagnosed and managed in primary care settings. …”
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Evaluating the radiosensitivity of the oral microbiome to predict radiation-induced mucositis in head and neck cancer patients: A prospective trial by Andreas R. Thomsen, Elsa Beatriz Monroy Ordonez, Michael Henke, Benedikt Luka, Jörg Sahlmann, Henning Schäfer, Vivek Verma, Nadine Schlueter, Anca-Ligia Grosu, Tanja Sprave

“…Conclusions: It is necessary to establish reliable predictors of severe OM before treatment in H&N cancer to allow early management of treatment-related sequelae. This prospective trial illustrates that the intrinsic ex-vivo radiosensitivity of oral keratinocytes could be correlated with RT-induced OM in patients with H&N cancer. …”
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Chikungunya virus infection in the skin: histopathology and cutaneous immunological response by Natália Gedeão Salomão, Natália Gedeão Salomão, Luciana Araújo, Luiz José de Souza, Anna Luiza Young, Carlos Basílio-de-Oliveira, Rodrigo Panno Basílio-de-Oliveira, Jorge José de Carvalho, Priscilla Conrado Guerra Nunes, Juliana Fernandes da Silva Amorim, Douglas Valiati dos Santos Barbosa, Marciano Viana Paes, Kíssila Rabelo, Kíssila Rabelo, Flavia Dos Santos

“…Usually, these manifestations disappear, but they can become sequelae. Since the skin is the first line of defense against CHIKV infection, in this study, we aimed to investigate the immunohistopathological aspects of the skin of infected individuals during the acute phase of the disease by performing histopathological and ultrastructural analysis, detection and quantification of the viral genome, detection of viral antigen and immune cells, and cytokines/chemokines’ characterization. …”
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Effect of Hemoadsorption for Cytokine Removal in Pneumococcal and Meningococcal Sepsis by Francesca Leonardis, Viviana De Angelis, Francesca Frisardi, Chiara Pietrafitta, Ivano Riva, Tino Martino Valetti, Valentina Broletti, Gianmariano Marchesi, Lorenza Menato, Roberto Nani, Franco Marson, Mirca Fabbris, Luca Cabrini, Sergio Colombo, Alberto Zangrillo, Carlo Coniglio, Giovanni Gordini, Lucia Stalteri, Giovanni Giuliani, Vittorio Dalmastri, Gaetano La Manna

“…From this first experience, extracorporeal cytokine removal seems to be a valid and safe therapy in the management of meningococcal and pneumococcal diseases and may contribute to the patient stabilization and prevention of severe sequelae. Further studies are required to confirm efficacy in a larger context.…”
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Impact of surgical site infection (SSI) following gynaecological cancer surgery in the UK: a trainee-led multicentre audit and service evaluation by Rachel L O’Donnell, Georgios Angelopoulos, James P Beirne, Ioannis Biliatis, Helen Bolton, Melissa Bradbury, Elaine Craig, Ketan Gajjar, Michelle L Mackintosh, Wendy MacNab, Thumuluru Kavitha Madhuri, Mark McComiskey, Eva Myriokefalitaki, Claire L Newton, Nithya Ratnavelu, Sian E Taylor, Amudha Thangavelu, Sarah A Rhodes, Emma J Crosbie, Richard J Edmondson, Yee-Loi Louise Wan

“…Clinicopathological data were collected, and wound complications and their sequelae were recorded during the 30 days following surgery.Results In total, 339 women underwent laparotomy for suspected gynaecological cancer during the study period. …”
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Joint Group and Multi Institutional Position Opinion: Cirrhotic Cardiomyopathy—From Fundamentals to Applied Tactics by Ivan Rankovic, Ivana Babic, Jelena Martinov Nestorov, Jelena Bogdanovic, Maja Stojanovic, Jovanka Trifunovic, Nikola Panic, Mihailo Bezmarevic, Jelena Jevtovic, Dusan Micic, Vladimir Dedovic, Nemanja Djuricic, Filip Pilipovic, Elena Curakova Ristovska, Tijana Glisic, Sanja Kostic, Nemanja Stojkovic, Nata Joksimovic, Mileva Bascarevic, Aleksandra Bozovic, Lewis Elvin, Ajibola Onifade, Keith Siau, Elizaveta Koriakovskaia, Vladimir Milivojevic

“…This is not only a review but also a comprehensive distillation of the insights from practicing clinical hepatologists and other specialties engaged in advanced approaches to treating liver disease and its sequelae.…”
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Radiological abnormalities persist following COVID-19 and correlate with impaired health-related quality of life: a prospective cohort study of hospitalised patients by Rhian M Touyz, Ninian N Lang, Kevin G Blyth, Naveed Sattar, Patrick B Mark, Stefan Siebert, Colin Berry, Iain McInnes, Giles Roditi, Neil Basu, David Corcoran, Kenneth Mangion, Alex McConnachie, David Carrick, Jaclyn Carberry, Stuart Watkins, Paul Welsh, Sabrina Nordin, Katherine Scott, Christian Delles, Bernard Kelly, Fraser Goldie, John GF Cleland, Sharon Kean, Peter Kellman, David J Lowe, Andrew J Morrow, Antonia Ho, Rosemary Woodward, Tracey Hopkins, Ryan Wereski, Massimo Palmarini, Alasdair McIntosh, Campbell Rogers, Ammani Brown, Catherine Bagot, Kathryn Scott, Robert Sykes, Colin Church, Claire Rooney, Nicola Ryan, Clare Orange, Dirk Husmeier, Xiaoyu Luo, PETER W MACFARLANE, Heerajnarain Bulluck, Iain Findlay, Evonne McLennan, Michael Briscoe, Oliver Peck, Alastair J Rankin, Gruschen Veldtman, Varun Sharma, Kathryn McLaren, Elaine Butler, Sarah Mullen, Andrew Morrow, Patrick Mark, Daniel Doherty, Alexander Payne, Jennifer S Lees, Kaitlin J Mayne, Louise Inglis, Anna Kamdar, Hannah Bayes, Vivienne B Gibson, Lynsey Gillespie, Douglas Grieve, Pauline Hall Barrientos, Christopher McGinley, Connor Mckee, Sarah Allwood-Spiers, Sarah Weeden, Laura Knox, Lynn Abel, David Stobo, Andrew Dougherty, Liam Peng, David Barrie Stobo, Sylvia Wright, Stephen Dobbin, Keith Gillis, Sarah A Spiers, Ian Fergus, Kirsty Fallon, Lesley Gilmour, Chloe Cowan, Jurgen Van-Melckebeke, Kim Moran-Jones, Debra Stuart, Maureen Travers, Laura Dymock, Fiona Savage, Nicola Tynan, Sau Lee Chang, Mhairi Dupre, Lindsey Norton, George Bruce, Rosario Gonzalez-Lopez, Rebecca Stace, Dionne Russell, Jean Watt, Shahid Latif, Nick Hill, Amy Collinsworth, Ross McGeoch Vera Lennie, Robin P Weir

“…We present a prospective, observational, multicentre cohort study using multimodality imaging to describe the pulmonary sequelae of patients hospitalised with COVID-19, predictors of persistent abnormal radiology and implications on health status.Methods In survivors of COVID-19, we performed convalescent CT pulmonary angiogram and high-resolution CT imaging as part of the CISCO-19 study (ClinicalTrials.gov ID NCT04403607). …”
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UBICU: A Gamified Respiratory Incentive System for Pulmonary Re-Expansion by Jaime Aguilar-Zambrano, Esther C. Wilches-Luna, Helberg Asencio-Santofimio, Manuel Valencia, Diana Riveros, Andres Navarro, Juan Carlos Martinez, Eugenio Tamura, Jose Angel Loaiza, Julian Hernandez, Diana Sanchez, Juan David Garcia, Leonardo Arzayus-Patino, Valeria Perez-Hortua, Elizabeth Moncada, Melissa Ramirez

“…Pulmonary complications can arise due to trauma, postoperative conditions, or as sequelae of diseases such as COVID-19. To help patients restore lung functionality, most undergo lung re-expansion physiotherapy using a Respiratory Incentive Spirometer. …”
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Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design. by Rachel S Gross, Tanayott Thaweethai, Erika B Rosenzweig, James Chan, Lori B Chibnik, Mine S Cicek, Amy J Elliott, Valerie J Flaherman, Andrea S Foulkes, Margot Gage Witvliet, Richard Gallagher, Maria Laura Gennaro, Terry L Jernigan, Elizabeth W Karlson, Stuart D Katz, Patricia A Kinser, Lawrence C Kleinman, Michelle F Lamendola-Essel, Joshua D Milner, Sindhu Mohandas, Praveen C Mudumbi, Jane W Newburger, Kyung E Rhee, Amy L Salisbury, Jessica N Snowden, Cheryl R Stein, Melissa S Stockwell, Kelan G Tantisira, Moriah E Thomason, Dongngan T Truong, David Warburton, John C Wood, Shifa Ahmed, Almary Akerlundh, Akram N Alshawabkeh, Brett R Anderson, Judy L Aschner, Andrew M Atz, Robin L Aupperle, Fiona C Baker, Venkataraman Balaraman, Dithi Banerjee, Deanna M Barch, Arielle Baskin-Sommers, Sultana Bhuiyan, Marie-Abele C Bind, Amanda L Bogie, Tamara Bradford, Natalie C Buchbinder, Elliott Bueler, Hülya Bükülmez, B J Casey, Linda Chang, Maryanne Chrisant, Duncan B Clark, Rebecca G Clifton, Katharine N Clouser, Lesley Cottrell, Kelly Cowan, Viren D'Sa, Mirella Dapretto, Soham Dasgupta, Walter Dehority, Audrey Dionne, Kirsten B Dummer, Matthew D Elias, Shari Esquenazi-Karonika, Danielle N Evans, E Vincent S Faustino, Alexander G Fiks, Daniel Forsha, John J Foxe, Naomi P Friedman, Greta Fry, Sunanda Gaur, Dylan G Gee, Kevin M Gray, Stephanie Handler, Ashraf S Harahsheh, Keren Hasbani, Andrew C Heath, Camden Hebson, Mary M Heitzeg, Christina M Hester, Sophia Hill, Laura Hobart-Porter, Travis K F Hong, Carol R Horowitz, Daniel S Hsia, Matthew Huentelman, Kathy D Hummel, Katherine Irby, Joanna Jacobus, Vanessa L Jacoby, Pei-Ni Jone, David C Kaelber, Tyler J Kasmarcak, Matthew J Kluko, Jessica S Kosut, Angela R Laird, Jeremy Landeo-Gutierrez, Sean M Lang, Christine L Larson, Peter Paul C Lim, Krista M Lisdahl, Brian W McCrindle, Russell J McCulloh, Kimberly McHugh, Alan L Mendelsohn, Torri D Metz, Julie Miller, Elizabeth C Mitchell, Lerraughn M Morgan, Eva M Müller-Oehring, Erica R Nahin, Michael C Neale, Manette Ness-Cochinwala, Sheila M Nolan, Carlos R Oliveira, Onyekachukwu Osakwe, Matthew E Oster, R Mark Payne, Michael A Portman, Hengameh Raissy, Isabelle G Randall, Suchitra Rao, Harrison T Reeder, Johana M Rosas, Mark W Russell, Arash A Sabati, Yamuna Sanil, Alice I Sato, Michael S Schechter, Rangaraj Selvarangan, S Kristen Sexson Tejtel, Divya Shakti, Kavita Sharma, Lindsay M Squeglia, Shubika Srivastava, Michelle D Stevenson, Jacqueline Szmuszkovicz, Maria M Talavera-Barber, Ronald J Teufel, Deepika Thacker, Felicia Trachtenberg, Mmekom M Udosen, Megan R Warner, Sara E Watson, Alan Werzberger, Jordan C Weyer, Marion J Wood, H Shonna Yin, William T Zempsky, Emily Zimmerman, Benard P Dreyer, RECOVER-Pediatric Consortium

“…<h4>Importance</h4>The prevalence, pathophysiology, and long-term outcomes of COVID-19 (post-acute sequelae of SARS-CoV-2 [PASC] or "Long COVID") in children and young adults remain unknown. …”
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Perspectives from the 2nd International Post-Tuberculosis Symposium: mobilising advocacy and research for improved outcomes by B.W. Allwood, R. Nightingale, G. Agbota, S. Auld, G.P. Bisson, A. Byrne, R. Dunn, D. Evans, G. Hoddinott, G. Günther, Z. Islam, J.C. Johnston, G. Kalyatanda, C. Khosa, S. Marais, G. Makanda, O.M. Mashedi, J. Meghji, C. Mitnick, C. Mulder, E. Nkereuwem, O. Nkereuwem, O.B. Ozoh, A. Rachow, K. Romanowski, J.A. Seddon, I. Schoeman, F. Thienemann, N.F. Walker, D.T. Wademan, R. Wallis, M.M. van der Zalm

“…Ten academic working groups set their own goals and covered the following thematic areas: 1) patient engagement and perspectives; 2) epidemiology and modelling; 3) pathogenesis of post-TB sequelae; 4) post-TB lung disease; 5) cardiovascular and pulmonary vascular complications; 6) neuromuscular & skeletal complications; 7) paediatric complications; 8) economic-social and psychological (ESP) consequences; 9) prevention, treatment and management; 10) advocacy, policy and stakeholder engagement. …”
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Chronic lung lesions in COVID-19 survivors: predictive clinical model by Paulo A Lotufo, Juliana C Ferreira, Eloisa Bonfa, Anna S Levin, Rodrigo Caruso Chate, Marta Imamura, Esper G Kallas, Roger Chammas, Thais Mauad, Izabel Marcilio, Nelson Gouveia, Ricardo Nitrini, José Eduardo Krieger, Marcio Valente Yamada Sawamura, Michelle Louvaes Garcia, Cristiano Gomes, Guilherme Fonseca, Jorge Hallak, Luis Yu, Marcio Mancini, Maria Elizabeth Rossi, Thiago Avelino-Silva, Edivaldo M Utiyama, Aluisio C Segurado, Beatriz Perondi, Anna Miethke-Morais, Amanda C Montal, Leila Harima, Marjorie F Silva, Marcelo C Rocha, Maria Amélia de Jesus, Carolina Carmo, Clarice Tanaka, Julio F M Marchini, Thaís Guimarães, Ester Sabino, Carlos Roberto Ribeiro Carvalho, Celina Almeida Lamas, Diego Armando Cardona Cardenas, Daniel Mario Lima, Paula Gobi Scudeller, João Marcos Salge, Cesar Higa Nomura, Marco Antonio Gutierrez, Adriana L Araújo, Bruno F Guedes, Carolina S Lázari, Cassiano C Antonio, Claudia C Leite, Emmanuel A Burdmann, Euripedes C Miguel, Fabio R Pinna, Fabiane Y O Kawano, Geraldo F Busatto, Giovanni G Cerri, Heraldo P Souza, Izabel C Rios, Larissa S Oliveira, Linamara R Batisttella, Luiz Henrique M Castro, Marcello M C Magri, Maria Cassia J M Corrêa, Maria Cristina P B Francisco, Maura S Oliveira, Orestes V Forlenza, Ricardo F Bento, Rodolfo F Damiano, Rossana P Francisco, Solange R G Fusco, Tarcisio E P Barros-Filho, Wilson J Filho

“…Given that these examinations are highly accessible and low cost, this protocol can be automated and implemented in different countries for early detection of COVID-19 sequelae.…”
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Real-world effectiveness and causal mediation study of BNT162b2 on long COVID risks in children and adolescentsResearch in context by Qiong Wu, Bingyu Zhang, Jiayi Tong, L. Charles Bailey, H. Timothy Bunnell, Jiajie Chen, Elizabeth A. Chrischilles, Dimitri A. Christakis, Stephen M. Downs, Kathryn Hirabayashi, Aaron D. Mishkin, Abu S.M. Mosa, Nathan M. Pajor, Suchitra Rao, Hanieh Razzaghi, Hayden T. Schwenk, Marion R. Sills, Huiyuan Wang, Linbo Wang, Yudong Wang, Dazheng Zhang, Ting Zhou, Ravi Jhaveri, Eric J. Tchetgen Tchetgen, Jeffrey S. Morris, Christopher B. Forrest, Yong Chen

“…The outcomes of interest include conclusive or probable diagnosis of long COVID following a documented SARS-CoV-2 infection, and body-system-specific condition clusters of post-acute sequelae of SARS-CoV-2 infection (PASC), such as cardiac, gastrointestinal, musculoskeletal, respiratory, and syndromic categories. …”
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FERN: is it possible to conduct a randomised controlled trial of intervention or expectant management for early-onset selective fetal growth restriction in monochorionic twin pregn... by Kerry Woolfall, Jamie J Kirkham, Jane Sandall, Mariana Popa, Enrico Lopriore, Mark Turner, Shakila Thangaratinam, Aris T Papageorghiou, Andrew Sharp, Lawrence Impey, Andy Healey, Jessica Mendoza, Asma Khalil, Dharmintra Pasupathy, Brigitte Vollmer, Zarko Alfirevic, Rajeswari Parasuraman, Jan Deprest, Richard Edmund Ashcroft, Kurt Hecher, Smriti Prasad, Baskaran Thilaganathan, Richard J Jackson, Tracy Karen Mitchell, Natasha Fenwick, Monique C Haak, Liesbeth Lewi, Shauna Leven, Fabricio Da Silva Costa, Odai Yaghi, Tracey Ricketts, George Attilakos, Carolyn Bailie, Christine Cornforth, Mark Denbow, Louise Hardman, Jane Harrold, Joel Marsden, Tommy Mousa, Surabhi Nanda, Michelle Watson, Karen Wilding, Dilly Anumba, Edward D Johnstone, Yoav Yinon, Ahmet Baschat

“…The condition poses unique management difficulties: on the one hand, continuation of the pregnancy carries a risk of death of the smaller twin, with a high risk of co-twin demise (40%) or co-twin neurological sequelae (30%). On the other, early delivery to prevent the death of the smaller twin may expose the larger twin to prematurity, with the associated risks of long-term physical, emotional and financial costs from neurodisability, such as cerebral palsy.When there is severe and early sFGR, before viability, delivery is not an option. …”
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Development of Fulminant Type 1 Diabetes Mellitus in a Patient with DRESS Syndrome by Pedro Perez, Wilson Sze, Daniel Lozeau, Dipa Avichal, Joshua Miller

“…DRESS is often misdiagnosed and challenging to clinically manage due to the disease’s myriad presentations, acute complications, and long-term sequela after initial resolution. We present the case of a 39-year-old female patient that developed type 1 diabetes as a sequela of DRESS. …”
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