Severe Acute Respiratory Syndrome Coronavirus 2 Infection Symptoms in Pregnancy and Maternal and Neonatal Complications Due to COVID-19: A Systematic Review by Sepideh Miraj, Azadeh Asgarian, Abolfazl Mohammadbeigi, Maryam Derakhshani

“…Neonatal ICU admission, newborn death, neonatal sepsis, low birth weight and respiratory distress syndrome, tachypnoea, asphyxia and pneumothorax were the most common outcomes of COVID-19 infection in offspring of pregnant subjects. …”
Get full text

Reconciling the IPC and Two-Hit Models: Dissecting the Underlying Cellular and Molecular Mechanisms of Two Seemingly Opposing Frameworks by Carlos F. M. Morris, Muhammad Tahir, Samina Arshid, Mariana S. Castro, Wagner Fontes

“…Amongst those the two-hit model stands as a plausible and intuitive framework that explains some of the most frequent clinical outcomes seen in injuries like trauma and sepsis. This model states that a first hit serves as a priming event upon which sequential insults can build on, culminating on maladaptive inflammatory responses. …”
Get full text

A rare neurosurgical emergency: case report of spontaneous lumbar subdural empyema by Svetozar Stanković, Milan Lepić, Ivan Bogićević, Jadranka Stanković, Goran Pavlicević

“…The patient’s condition deteriorated, developing severe radicular pain, high-grade fever, and signs of sepsis within seven days. Laboratory tests showed elevated inflammatory markers. …”
Get full text

Cytotoxicity towards human endothelial cells, induced by neutrophil myeloperoxidase: protection by ceftazidime by M. Mathy-Hartert, G. Deby-Dupont, C. Deby, L. Jadoul, A. Vandenberghe, M. Lamy

“…These antioxidant properties of CAZ may be clinically useful in pathological situations where excessive activation of neutrophils occurs, such as in sepsis.…”
Get full text

Patient with Jaundice, Dyspnea and Hyperferritinemia after COVID-19 by V. R. Grechishnikova, P. E. Tkachenko, M. S. Zharkova, T. P. Nekrasova, V. T. Ivashkin

“…The possibility of hemophagocytic syndrome development should be considered, including cases of overlap syndrome with sepsis, in patients with unresolved jaundice, hyperferritinemia after coronavirus infection. …”
Get full text

Comparing Fluconazole and Nystatin as Antifungal Prophylactics in Very Low Birth Weight Infants: A Randomized Clinical Trial by Leila Asgarzadeh, Majid Mahallei, Manizheh Mostafa Gharehbaghi

“…Objectives: Systemic fungal infections (SFIs) account for 12% of all late-onset sepsis among very low birth weight (VLBW) infants and result in adverse long-term neurodevelopmental outcomes among survivors. …”
Get full text

The Role of Complement System in Septic Shock by Jean Charchaflieh, Jiandong Wei, Georges Labaze, Yunfang Joan Hou, Benjamin Babarsh, Helen Stutz, Haekyung Lee, Samrat Worah, Ming Zhang

“…Published reports suggest a protective role of mannose-binding lectin (MBL) against sepsis. Our preliminary study of MBL-associated serine protease-2 (MASP-2) in septic shock patients indicated that acute decrease of MASP-2 in the early phase of septic shock might correlate with in-hospital mortality. …”
Get full text

Prospective Clinical Trial for Septic Arthritis: Cartilage Degradation and Inflammation Are Associated with Upregulation of Cartilage Metabolites by Hagen Schmal, Anke Bernstein, Matthias J. Feucht, Benjamin Erdle, Jan M. Pestka, That Minh Pham, Eva Johanna Kubosch

“…Higher synovial IL-1β concentrations were associated with clinical parameters indicating a higher disease severity (p<0.03) excluding the incidence of sepsis. Additionally, intra-articular IL-1β levels correlated with inflammatory serum parameters as leucocyte counts (LC) and C-reactive protein concentrations (p<0.05) but not with age or comorbidity. …”
Get full text

Comparison of Risks Factors for Unplanned ICU Transfer after ED Admission in Patients with Infections and Those without Infections by Jeffrey Che-Hung Tsai, Ching-Wan Cheng, Shao-Jen Weng, Chin-Yin Huang, David Hung-Tsang Yen, Hsiu-Ling Chen

“…The objectives of this study were to compare the risk factors for unplanned intensive care unit (ICU) transfer after emergency department (ED) admission in patients with infections and those without infections and to explore the feasibility of using risk stratification tools for sepsis to derive a prediction system for such unplanned transfer. …”
Get full text

Bowel Perforation in Premature Infants with Necrotizing Enterocolitis: Risk Factors and Outcomes by Lingling Yu, Jianmei Tian, Xingli Zhao, Ping Cheng, Xiaoqian Chen, Yun Yu, Xiaochun Ding, Xueping Zhu, Zhihui Xiao

“…The perforated NEC group, compared to the nonperforated NEC group, had significantly lesser gestational age, lower birth weight, higher prevalence of apnea, mechanical ventilation, sepsis and shock, lower blood pH, higher levels of blood glucose, abnormal WBC count and thrombocytopenia, and elevated CRP (all P<0.05). …”
Get full text

A Case of Odontogenic Infection by Streptococcus constellatus Leading to Systemic Infection in a Cogan’s Syndrome Patient by Masanobu Abe, Yoshiyuki Mori, Ryoko Inaki, Yae Ohata, Takahiro Abe, Hideto Saijo, Kazumi Ohkubo, Kazuto Hoshi, Tsuyoshi Takato

“…Our case report presents a patient with sepsis due to a Streptococcus constellatus (S. constellatus) odontogenic infection in a 64-year-old-immunocompromised woman with Cogan’s syndrome. …”
Get full text

Estimating the Risk of Maternal Death at Admission: A Predictive Model from a 5-Year Case Reference Study in Northern Uganda by Gasthony Alobo, Cristina Reverzani, Laura Sarno, Barbara Giordani, Luigi Greco

“…Direct obstetric causes contributed to 73.8% of maternal deaths; the most common were haemorrhage (42.7%), sepsis (24.0%), hypertensive disorders (18.7%) and complications of abortion (2.1%), whereas malaria (23.5%) and HIV/AIDS (20.6%) were the leading indirect causes. …”
Get full text

Expression Profiling of Long Noncoding RNA Splice Variants in Human Microvascular Endothelial Cells: Lipopolysaccharide Effects In Vitro by Imran H. Chowdhury, Hema P. Narra, Abha Sahni, Kamil Khanipov, Casey L. C. Schroeder, Jignesh Patel, Yuriy Fofanov, Sanjeev K. Sahni

“…This study illustrates the genome-wide regulation of endothelial lncRNA splice variants in response to LPS and provides a foundation for further investigations of differentially expressed lncRNA transcripts in endothelial responses to LPS and pathophysiology of sepsis/septic shock.…”
Get full text

Caracterización de malformaciones congénitas en recién nacidos vivos by Carlos Acosta Batista, Rosali Mullings Pérez

“…La mayoría de las madres pertenecían al grupo de edades de 20-35 años, padecían hipertensión arterial y durante el embarazo, las principales enfermedades que presentaron fueron las sepsis y la anemia.…”
Get full text

How to Recondition Ex Vivo Initially Rejected Donor Lungs for Clinical Transplantation: Clinical Experience from Lund University Hospital by Sandra Lindstedt, Atli Eyjolfsson, Bansi Koul, Per Wierup, Leif Pierre, Ronny Gustafsson, Richard Ingemansson

“…One patient died due to sepsis after 95 days, and one due to rejection after 9 months. …”
Get full text

Factors Affecting the Weaning from Nasal CPAP in Preterm Neonates by Shantanu Rastogi, Hariprem Rajasekhar, Anju Gupta, Alok Bhutada, Deepa Rastogi, Jen-Tien Wung

“…Univariate analysis showed that chorioamnionitis, intubation, surfactant use, PDA, sepsis/NEC, anemia, apnea, GER and IVH were significantly associated with the time to NCPAP wean. …”
Get full text

Goal-Oriented Respiratory Management for Critically Ill Patients with Acute Respiratory Distress Syndrome by Carmen Sílvia Valente Barbas, Gustavo Faissol Janot Matos, Marcelo Britto Passos Amato, Carlos Roberto Ribeiro Carvalho

“…Rapid administration of antibiotics and resuscitative measures in case of sepsis and septic shock associated with protective ventilatory strategies and early short-term paralysis associated with differential ventilatory techniques (recruitment maneuvers with adequate positive end-expiratory pressure titration, prone position, and new extracorporeal membrane oxygenation techniques) in severe ARDS can help improve its prognosis. …”
Get full text

Reduced Plasma Nonesterified Fatty Acid Levels and the Advent of an Acute Lung Injury in Mice after Intravenous or Enteral Oleic Acid Administration by Cassiano Felippe Gonçalves de Albuquerque, Patrícia Burth, Mauricio Younes Ibrahim, Diogo Gomes Garcia, Patrícia Torres Bozza, Hugo Caire Castro Faria Neto, Mauro Velho Castro Faria

“…Increased blood concentration of oleic acid (OLA) and other fatty acids is detected in many pathological conditions. In sepsis and leptospirosis, high plasma levels of NEFA and low albumin concentrations are correlated to the disease severity. …”
Get full text

Helicobacter pylori promotes intestinal flora imbalance and hepatic metabolic disorders under arsenic stress by Linmin Zhong, Qiling Yang, Yiming Shao, Shanwen Hu, Lianxian Guo

Get full text

Perbedaan Profil Abses Hati Pyogenic dengan Amoebic pada Pasien Abses Hati Rawat Inap di RSUD Dr Soetomo Tahun 2016-2019 by Annisya Dinda Paramitha, Ulfa Kholili, Bagus Setyoboedi

“…Komplikasi yang paling umum adalah efusi pleura (37,9%) dan sepsis (34,5%). Kematian hanya terjadi pada abses hati pyogenik sebesar 13,8%, sedangkan pada amoebik 0%. …”
Get full text