Acute Esophageal Necrosis in a Septic Patient with a History of Cardiovascular Disease by Michael Coles, Victoria Madray, Pearl Uy

“…His hospital course was complicated by possible sepsis secondary to aspiration pneumonia and hematemesis secondary to acute ischemic esophageal necrosis as noted on upper endoscopy. …”
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Ovarian hyperstimulation syndrome. A case report by Práxedes de Regla Rojas Quintana, Sandra Gómez Fonseca, Alejandrina Najarro Navarro

“…For these reasons, the case of a patient who underwent medical and surgical treatment, with in vitro fertilization and embryo transfer, who developed severe ovarian hyperstimulation syndrome with pregnancy si presente Since the syndrome could not be controlled and worsened with pregnancy and sepsis, with changes in addition to hepatorenal dysfunction, it was decided to terminate the pregnancy at six weeks of gestation, since the patient's life was in danger, and antibiotic therapy was started for sepsis. …”
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Septic Thrombophlebitis Caused by Fusobacterium necrophorum in an Intravenous Drug User by D. Dimitropoulou, M. Lagadinou, T. Papayiannis, V. Siabi, C. A. Gogos, M. Marangos

“…Lemierre’s syndrome, also referred to as post-anginal sepsis or necrobacillosis, is a suppurative thrombophlebitis of the internal jugular vein. …”
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Severe Clostridial Pyomyoma following an Abortion Does Not Always Require Surgical Intervention by Daphna Stroumsa, Eliel Ben-David, Nurith Hiller, Drorith Hochner-Celnikier

“…In selected cases of infected myoma complicated by clostridial sepsis, refraining from surgical intervention is a possible therapeutic approach.…”
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Immunosuppression with Antitumour Necrosis Factor Therapy Leading to Strongyloides Hyperinfection Syndrome by Muhammad Farhan Khaliq, Rayan E. Ihle, James Perry

“…Here, we present a case of Strongyloides hyperinfection in a 75-year-old male secondary to sepsis and chronic immunosuppression due to TNF-α inhibitors. …”
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Association between Shock Index and Emergency Department Cardiac Arrest by Chao-Tung Chen, Pei-Ming Wang, Chao-Hsin Wu, Chih-Wei Wei, Tai-Lin Huang

“…The aOR (CI) in the five etiologies was 1.3 (1.1–1.6) for hypoxia, 1.8 (1.6–2.1) for cardiac cause, 1.3 (0.98–1.7) for bleeding, 1.3 (1.03–1.6) for sepsis, and 1.9 (1.5–2.1) for other metabolic problems. …”
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Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients by Susanna Lam, Ngee-Soon Lau, Jerome Martin Laurence, Deborah Jean Verran

“…However, we describe three cases in which persistent or recurrent surgical site sepsis occurred, whilst NPWT was being deployed in adults with either wound dehiscence or initial SSI. …”
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The Role of T Helper (TH)17 Cells as a Double-Edged Sword in the Interplay of Infection and Autoimmunity with a Focus on Xenobiotic-Induced Immunomodulation by Nasr Y. A. Hemdan, Ahmed M. Abu El-Saad, Ulrich Sack

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Prevalence and Management of Septic Shock among Children Admitted at the Kenyatta National Hospital, Longitudinal Survey by Varsha Vekaria-Hirani, Rashmi Kumar, Rachel N. Musoke, Ezekiel M. Wafula, Idris N. Chipkophe

“…Paediatric septic shock is a subset of sepsis associated with high mortality. Implementing the existing international Surviving Sepsis Campaign Guidelines 2012 (SSCG) have contributed to reduction of mortality in many places but these have not been adopted in our setting. …”
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Skin and Soft Tissue Infections in Patients with Solid Tumours by Diamantis P. Kofteridis, Antonios Valachis, Eirini Koutsounaki, Sofia Maraki, Eleni Mavrogeni, Foteini N. Economidou, Dimitra Dimopoulou, Kostas Kalbakis, Vassilis Georgoulias, George Samonis

“…Five patients (7%) died due to sepsis. None was neutropenic. Severe sepsis on admission (𝑃=0.002) and prior blood transfusion (𝑃=0.043) were independent predictors of treatment failure. …”
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Therapeutic Drug Monitoring of Vancomycin in Hemodialysis Patients in a Hospital in North-East Romania by Aurelia Crețu, Luanda Irina Mititiuc, Iulia-Daniela Lungu, Mihaela Mihaila, Irina Dima, Adrian Covic, Cristina Mihaela Ghiciuc

“…Hemodialysis patients are very fragile patients and the presence of CVCs increases the risk of sepsis. We conducted a prospective study, evaluating the needs of changes in vancomycin dosing for treatment based on the use of the new 2020 vancomycin dosing guidelines, to increase drug safety (preventing subtherapeutic or supratherapeutic doses and offering therapeutic concentrations of the drug) in a particular group of patients with sepsis caused by catheter infections and being on intermittent hemodialysis. …”
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Effect of Negative Pressure Therapy on the Inflammatory Response of the Intestinal Microenvironment in a Porcine Septic Model by Kenneth C. Norbury, Mary Pat Moyer

“…In a swine model of ischemia/reperfusion injury coupled with sepsis, we have previously shown attenuation of secondary organ injury and decreased mortality with negative pressure therapy (NPT). …”
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Prognostic Value of the Red Blood Cell Distribution Width-to-Albumin Ratio in Critically Ill Older Patients with Acute Kidney Injury: A Retrospective Database Study by Lei Guo, Dezhun Chen, Bihuan Cheng, Yuqiang Gong, Benji Wang

“…The risk of AKI is complicated when RRT occurs; sepsis and septic shock increase with RA levels.…”
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Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1β,... by André L. F. Sampaio, Jesmond Dalli, Vincenzo Brancaleone, Fulvio D'Acquisto, Mauro Perretti, Carmen Wheatley

“…NOS/•NO inhibitors are potential therapeutics for sepsis, yet they increase clinical mortality. However, there has been no in vivo investigation of the (in vitro) •NO scavenger, cobalamin’s (Cbl) endogenous effects on NOS/•NO/inflammatory mediators during the immune response to sepsis. …”
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Profile of Candida bloodstream infections among blood culture-positive patients at a tertiary care hospital by S. Shreya, K. Sandhya Bhat

“…Automated blood cultures are the gold standard tools for the evaluation of suspected cases of sepsis. This study was done to document the proportion of candidemia, Candida profile, susceptibility to fluconazole, and associated risk factors among suspected cases of sepsis. …”
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Impact of rapid antibiotic susceptibility testing for Gram-negative bacteremia varies by pathogen type and resistance: a secondary analysis of the RAPIDS GN trial by Ritu Banerjee, Abhigya Giri, Lauren Komarow, Maria Souli, Sarah B. Doernberg, Robin Patel

“…This analysis of patients with sepsis previously enrolled in a randomized controlled clinical trial demonstrates that rapid susceptibility testing of bacteria from blood cultures had the greatest impact for patients with antibiotic-resistant infections. …”
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The maternal morbidity behavior during the puerperium. Cienfuegos, 2020 by Dayami Elizabet Díaz Hurtado, Yuliett Mora Pérez, Luciano Nuñez Almoguea, Yuliemi Basso Basso Mora

“…The postpartum women with maternal morbidity due to severe sepsis were 79 women (2.2%) and with non-serious morbidity 397 women (11.1%). …”
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Complement activated granulocytes can cause autologous tissue destruction in man by E. Löhde, H. Raude, M. Lück, E. Kraas, W. Lierse

“…Activation of polymorphonuclear granulocytes (PMNs) by C5a is thought to be important in the pathogenesis of multiple organ failure during sepsis and after trauma. In our experiment exposure of human PMNs to autologous zymosan activated plasma (ZAP) leads to a rapid increase in chemiluminescence. …”
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Risk Factor-Specific Mortality Analysis of the Outborn Newborns to Improve the Neonatal Mortality Rate: A Cross-Sectional Descriptive Study by Tapan K. Kundu, Abhilash Chatterjee, Mitali Bera, Aditi Chowdhury, Riya Guchhait

“…The causes of death were sepsis in 35.23%, perinatal asphyxia in 22.78%, and prematurity (<28 weeks) and ELBW (≤999 grams) in 16.73%. …”
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Balancing inflammation: the specific roles of serum amyloid A proteins in sterile and infectious diseasese by Tirthankar Mohanty, Katarina Miličević, Henri Göthert, Andreas Tillmann, Médea Padra, Praveen Papareddy, Heiko Herwald

“…SAA-/- mice carrying a deletion of the Saa1, Saa2, Saa3, and Saa4 serum amyloid A genes have better survival rates in sterile sepsis but are more prone to bacterial sepsis than their SAA+/+ counterparts, emphasizing their dual functionality in immune regulation. …”
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