Showing 41 - 60 results of 333 for search '"senescence"', query time: 0.05s Refine Results
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    E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence. by Alicia Avenhaus, Milica Velimirović, Julia Bulkescher, Martin Scheffner, Felix Hoppe-Seyler, Karin Hoppe-Seyler

    Published 2025-02-01
    “…Of further note, repression of E6AP allows senescence induction in the presence of the anti-senescent HPV E7 protein. …”
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  3. 43

    Study on the Dynamic Biological Characteristics of Sca-1+ Hematopoietic Stem and Progenitor Cell Senescence by Shan Geng, Xin-Yi Mu, Xiong-Bin Chen, Ji-Ying Hou, Dao-Yong Jia, Chun-Yan Xu, Ya-Ping Wang

    Published 2015-01-01
    “…In accordance with that, the senescence of HSPCs also started from the middle age, since the self-renewal and differentiation ability remarkably decreased, and senescence-associated markers SA-β-GAL increased in the 6-month-old and the older groups. …”
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  4. 44

    Reduced UPF1 levels in senescence impair nonsense-mediated mRNA decay by Dahyeon Koh, Yebin Lee, Kyuchan Kim, Hyeong Bin Jeon, Chaehwan Oh, Sangik Hwang, Minjung Lim, Kwang-Pyo Lee, Yeonkyoung Park, Yong Ryoul Yang, Yoon Ki Kim, Donghwan Shim, Myriam Gorospe, Ji Heon Noh, Kyoung Mi Kim

    Published 2025-01-01
    “…Moreover, knockdown of UPF1 in proliferating WI-38 cells induces senescence, as evidenced by increased senescence-associated β-galactosidase activity, alterations in senescence-associated molecular markers, increased endogenous γ-H2AX levels, and reduced cell proliferation. …”
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    Citral Delays Postharvest Senescence of Kiwifruit by Enhancing Antioxidant Capacity under Cold Storage by Ling Wei, Chuying Chen, Chunpeng Wan, Ming Chen, Jinyin Chen

    Published 2021-01-01
    “…Collectively, the results indicated that citral treatment delays postharvest senescence and prolongs storage life by enhancing antioxidant capacity in harvested kiwifruits. …”
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    Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells by Liping Mai, Guodong He, Jing Chen, Jiening Zhu, Shaoxian Chen, Xinghua Hou, Hui Yang, Mengzhen Zhang, Yueheng Wu, Qiuxiong Lin, Min Yang, Xiaohong Li

    Published 2021-01-01
    “…Here, we performed an investigation on the pathogenesis of hypoxia-induced senescence through proteomic analyses and aimed to explore the mechanisms of stem cell senescence. …”
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    Human placental extract improves liver cirrhosis in mice with regulation of macrophages and senescent cells by Natsuki Ishikawa, Yusuke Watanabe, Yuichirou Maeda, Tomoaki Yoshida, Naruhiro Kimura, Hiroyuki Abe, Akira Sakamaki, Hiroteru Kamimura, Takeshi Yokoo, Kenya Kamimura, Atsunori Tsuchiya, Shuji Terai

    Published 2025-03-01
    “…Furthermore, there was a decrease in the number of senescent cells in the liver and the mRNA levels of secrete senescence-associated secretory phenotype factors and Cdkn2a (p16). …”
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    Novel Approach to Bile Duct Damage in Primary Biliary Cirrhosis: Participation of Cellular Senescence and Autophagy by Motoko Sasaki, Yasuni Nakanuma

    Published 2012-01-01
    “…We have reported that cellular senescence in biliary epithelial cells (BECs) may be involved in bile duct lesions and that autophagy may precede the process of biliary epithelial senescence in PBC. …”
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  15. 55

    Chloride intracellular channel CLIC3 mediates fibroblast cellular senescence by interacting with ERK7 by Changjiao Luan, Yue Gao, Jun Zhao, Xiaohui Zhang, Chaofan Wang, Wentao Sun, Yucheng Li, Xinxing Yang, Jiaxiao Chen, Weili Liu, Weijuan Gong, Xingjie Ma

    Published 2025-01-01
    “…Abstract Cellular senescence (CS) is recognized as a critical driver of aging and age-related disorders. …”
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    Spraying Arginine at 5 Days before Harvest Delays Postharvest Broccoli Senescence via Nutrient Accumulation by SUN Yupeng, CHEN Ying, SHANG Qingwen, GUO Yanyin, ZHANG Yuxiao, WANG Yunqiao, XUE Qingyue

    Published 2025-01-01
    Subjects: “…arginine; broccoli; preharvest spraying; nutrient accumulation; storage quality; postharvest senescence…”
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    Mathematical model linking telomeres to senescence in Saccharomyces cerevisiae reveals cell lineage versus population dynamics by Anaïs Rat, Veronica Martinez Fernandez, Marie Doumic, Maria Teresa Teixeira, Zhou Xu

    Published 2025-01-01
    “…Abstract Telomere shortening ultimately causes replicative senescence. However, identifying the mechanisms driving replicative senescence in cell populations is challenging due to the heterogeneity of telomere lengths and the asynchrony of senescence onset. …”
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