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221
Plant traits, growth stage, and ash mass load control the vulnerability of potato, corn, and wheat crops to volcanic ashfall
Published 2025-02-01“…Distinct impact mechanisms were identified for each crop, including premature flower abscission, irreversible leaf yellowing, desiccation and senescence, and stalk lodging. Exposure of potato, corn, and wheat plants to ash mass loads >1 kg m−2 significantly reduced yield, but production quality was largely unaffected. …”
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222
Life stage hypothesis modeling determines insect vulnerability during developmental life stages to climate extremes
Published 2025-01-01“…We speculate that higher temperatures during the spring ephemeral host plant's flowering, and P. clodius' larval stage, may lead to earlier plant senescence and lower P. clodius growth. Because Parnassius butterflies are well studied from a global perspective, results may aid in understanding the potential indicator life stages of other insect species in montane environments to climatic changes. …”
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223
A Colorado Front Range grassland exhibits decreasing dominance of cheatgrass (Bromus tectorum) over time
Published 2025-01-01“…In grasslands of the Front Range of Colorado, a region experiencing a “spring/summer‐wet” precipitation pattern, cheatgrass can exploit early‐season soil moisture, but moderate rainfall continues into the growing season beyond the time of cheatgrass senescence. In this study, we measured how cheatgrass dominance changed over a 13‐year interval in a disturbed meadow along the Front Range of Colorado with a “spring/summer‐wet” precipitation pattern. …”
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224
Copolyamide-Based Modified Atmosphere Packaging Attenuates Phenolic Degradation and Maintains Postharvest Quality of <i>Rubus</i> Berries
Published 2025-01-01“…The highly perishable nature of <i>Rubus</i> berries, particularly their susceptibility to water loss and earlier senescence, significantly limits their shelf life. In this study, we investigated the mechanistic role of modified atmosphere packaging (MAP) on the physiochemical quality, phenolic metabolism, and antioxidant potential of blackberries and raspberries during cold storage (2 ± 1 °C) for 12 and 10 days, respectively. …”
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225
Synthesis of Arginase Inhibitors: An Overview
Published 2025-01-01“…It also mediates different cellular functions and processes such as proliferation, senescence, apoptosis, autophagy, and inflammatory responses in various cell types. …”
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226
Citrulline – The Powerhouse Nutrient for Cardiometabolic and Brain Health
Published 2025-02-01“…Emerging evidence suggests its potential in delaying endothelial senescence and preventing ferroptosis, establishing its role in vascular and neuroprotective strategies. …”
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227
Metabolite-Sensing Receptors: Emerging Targets for Modulating Chronic Pain Pathways
Published 2025-01-01“…TGR5, activated by bile acids, regulates inflammation and cellular senescence through pathways like NF-κB and p38. These receptors are promising therapeutic targets in chronic pain, addressing the metabolic and inflammatory factors underlying nociceptive sensitization and tissue degeneration. …”
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228
Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation-Related Tumorigenesis via Modulating Macrophages
Published 2022-01-01“…We found that HUC-MSCs cultured within 20 generations had no significant changes in proliferation, cell cycle, cellular senescence, apoptosis, and expression of mesenchymal stem cell markers. …”
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229
Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change
Published 2024-01-01“…., pathogen infection, nutrient deficiency, plant senescence, heat stress, drought, osmotic stress, and hypoxia induce autophagy in plants. …”
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230
Parity-Dependent Hemosiderin and Lipofuscin Accumulation in the Reproductively Aged Mouse Ovary
Published 2018-01-01“…Since lipofuscin is a widely accepted senescence marker and given the recently postulated role of lipofuscin-associated iron as a source of reactive oxygen species (ROS) in senescent cells, these findings suggest a possible pathogenic mechanism by which nulliparity contributes to an increased OC risk in the postmenopausal ovary.…”
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231
The Effect of the Application of Edible Coatings on or before Ultraviolet Treatment on Postharvested Longan Fruits
Published 2017-01-01“…Therefore, application of UV treatment followed by chitosan coating was found to be the best treatment combination for controlling enzymatic activities and reducing senescence rate of longan fruits.…”
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232
Farmers and Agricultural Extension Officers Perception of Striga gesnerioides (Willd.) Vatke Parasitism on Cowpea in the Upper East Region of Ghana
Published 2018-01-01“…Its effects on the host plants (cowpea) included stunted growth, leaf senescence, chlorosis, death of the crop, and reduced yield. …”
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233
Mechanistic relationship between obesity-induced inflammation triggering endothelial dysfunction and the initiation of atherosclerosis development
Published 2025-01-01“…The aim of this review is to summarize the effects of obesity-related inflammation on ED and its progression to atherosclerosis, focusing on cellular senescence, vascular aging, epigenetic modifications, reactive oxygen species, vascular calcification, and gut microbiota. …”
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234
The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy
Published 2014-01-01“…It has been shown that SkQ1 reduces clinical signs of retinopathy in senescence-accelerated OXYS rats, which are a known animal model of human age-related macular degeneration (AMD). …”
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235
Comparison of in vivo and in vitro preimplantation embryo development in OXYS and WAG rats
Published 2017-12-01“…OXYS rats are the model of precocious senescence. Numerous studies addressed physiology and behavior in rats of this strain during a postnatal period of their life, however, preimplantation development in OXYS rats has not yet been investigated. …”
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236
PRMT7: A Pivotal Arginine Methyltransferase in Stem Cells and Development
Published 2021-01-01“…Furthermore, we also discuss the roles of PRMT7 in cancer, adipogenesis, male reproduction, cellular stress, and cellular senescence, as well as the future perspectives of PRMT7-related studies. …”
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237
Mechanisms of RCD-1 pore formation and membrane bending
Published 2025-01-01“…Abstract Regulator of cell death-1 (RCD-1) governs the heteroallelic expression of RCD-1-1 and RCD-1-2, a pair of fungal gasdermin (GSDM)-like proteins, which prevent cytoplasmic mixing during allorecognition and safeguard against mycoparasitism, genome exploitation, and deleterious cytoplasmic elements (e.g., senescence plasmids) by effecting a form of cytolytic cell death. …”
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238
The beneficial effects of curcumin on aging and age-related diseases: from oxidative stress to antioxidant mechanisms, brain health and apoptosis
Published 2025-01-01“…These pathways are involved in cellular senescence and inflammation, and their modulation can improve cell function and help prevent disease. …”
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239
RNA N4‐acetylcytidine modification and its role in health and diseases
Published 2025-01-01“…Additionally, it systematically summarizes the essential functions and mechanisms of ac4C modification in normal biological processes, including stem cell fate determination, spermatogenesis and oogenesis, embryonic development, cellular senescence, and bone remodeling. Furthermore, this review delves into the central roles and molecular mechanisms of ac4C modification in regulating malignant proliferation, cell cycle arrest, EMT, drug resistance, cell death, cancer metabolism, and tumor immunotherapy. …”
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240
Physiological and pathological roles of PGAM5: An update and future trend
Published 2025-02-01“…Additionally, we summarize some novel roles of PGAM5 in cellular senescence, lipid metabolism, and immune response modulation in recent studies. …”
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