A novel de novo GABRA2 gene missense variant causing developmental epileptic encephalopathy in a Chinese patient by Li Yang, Xingyu Wan, Ran Hua, Junhong Jiang, Baotian Wang, Rui Tao, De Wu

“…Results The 6‐year‐old male proband presented with seizures starting at age two, along with global developmental delay and hypotonia. …”
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Advances in Serological Diagnosis of Neurocysticercosis in Korea by Chun-Seob Ahn, Jeong-Geun Kim, Sun Huh, Insug Kang, Yoon Kong

“…Further studies should focus on controlling late-onset intractable seizures and serological diagnosis of NC patients infected with few worms. …”
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The morphological, clinical, and prognostic factors in the management of giant anterior communicating artery aneurysms: A systematic review of cases by Roua Nasir, Midhat e Zahra Naqvi, Salaar Ahmed, Maarij ul Hassan, Rabeet Tariq, Saad Akhter Khan, Pia Koeskemeier, Rajiv K. Khajuria, Mohammad Hamza Bajwa, Sajjad Muhammad

“…Discussion and conclusion: Immediate suspicion is warranted for visual impairment with headaches in adults or seizures in the elderly. Direct clipping is the first-line treatment for ruptured cases closely followed by surgical bypass and trapping for unruptured cases. …”
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Clinical Features and Genetic Characteristics of XLID Patients With KDM5C Gene Mutations: Insights on Phenotype–Genotype Correlations From 175 Previous Cases and Identification of... by Mohammad‐Reza Ghasemi, Zahra Esmaeilizadeh, Sahand Tehrani Fateh, Hossein Sadeghi, Saman Bagheri, Farzad Hashemi‐Gorji, Morteza Sheikhi Nooshabadi, Rasoul Madannezhad, Toktam Sadat Tavabe Ghavami, Reza Mirfakhraie, Mohammad Miryounesi

“…Conclusions This study provides insights into the clinical and genetic characteristics of XLID associated with KDM5C gene mutations, highlighting the higher manifestation of seizures in males and also addressing the heterogeneity of phenotypes in females. …”
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Posterior reversible encephalopathy syndrome in a young male with IgA nephropathy and chronic kidney disease: a case report from the Maldives by Rajib Kumar Dey, Gunjan Khadka, Shifa Ishaq, Aishath Zeena Abdul Jaleel, Aminath Shafeenaz Moosa, Saifullah Muslim, Ali Nazeem

“…It can cause vasogenic edema of the brain and is characterized by nausea, vomiting, headache, seizures, visual changes, and other focal neurological deficits. …”
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Demographic and Clinical Presentation of Hospitalised Patients with SARS-CoV-2 During the First Omicron Wave by Mehool Patel, Elizabeth Aitken

“…Common COVID-19 presentations included delirium, falls, seizures, chronic obstructive pulmonary disease, and antenatal problems. …”
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Impact of the COVID-19 pandemic on cerebral venous sinus thrombosis in China: a comparative study by Xiaoming Zhang, Kun Fang, Duo Lan, Xiangqian Huang, Xunming Ji, Ran Meng, Da Zhou

“…After the COVID-19 pandemic, significant changes in symptoms and neuroimaging findings were observed, including increased visual impairment and decreased headache, neurological deficits, and seizures. Infection emerged as a prominent risk factor, including eight cases related to COVID-19 or vaccination. …”
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The emerging role of glycine receptor α2 subunit defects in neurodevelopmental disorders by Sean D. Fraser, Sean D. Fraser, Robert J. Harvey, Robert J. Harvey

“…As a result, microcephaly is observed in newborn Glra2 knockout mice, as well as defects in neuronal morphology, increased susceptibility to seizures, and defects in novel object recognition, motor memory consolidation, righting reflexes, novelty-induced locomotion in the open field test, and motivational reward tasks. …”
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Spinorphin Molecules as Opportunities for Incorporation into Spinorphin@AuNPs Conjugate Systems for Potential Sustained Targeted Delivery to the Brain by Stela Georgieva, Petar Todorov, Jana Tchekalarova

“…<b>Conclusions</b>: All the nanocompounds tested demonstrated the ability to reduce generalized tonic–clonic seizures. This suggests that these formulations may effectively target the underlying neuronal hyperexcitability. …”
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Diagnostic delay in cerebral creatine deficiency disorders: lessons learned from a cross-sectional single center study, and guanidinoacetate and creatine measurements in Switzerlan... by Christina Kaufman, Anaïs D’Andrea, Annette Hackenberg, Martin Poms, Olivier Braissant, Johannes Häberle

“…Patients with CCDD can present with a variety of unspecific symptoms: global developmental delay, speech-language disorder, behavioral abnormalities and seizures. Early treatment initiation is essential in AGAT and GAMT deficiencies to achieve a favorable outcome. …”
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Identifying biomarkers for epilepsy after cerebral malaria in Zambian children: rationale and design of a prospective observational study by Bo Zhang, Archana A Patel, Gretchen L Birbeck, Maitreyi Mazumdar, Suzanna Mwanza, Rosemary Nyirongo, Dixon Berejena, Joseph Kasolo, Tina Mwale, Violet Nambeye, Kafula Lisa Nkole, Nfwama Kawatu, Alexander Rotenberg

“…Outcome measures will include qualitative and quantitative analysis of routine EEG recordings, as well as clinical metrics in the acute and subacute period, including histidine-rich protein 2 levels of parasite burden, depth and length of coma, presence and severity of acute seizures, presence of hypoglycaemia, maximum temperature and 1-month post-CM neurodevelopmental assessment scores. …”
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<i>MECP2</i> Duplication Syndrome: AI-Based Diagnosis, Severity Scale Development and Correlation with Clinical and Molecular Variables by Lourdes Vega-Hanna, Dídac Casas-Alba, Sol Balsells, Mercè Bolasell, Patricia Rubio, Ana García-García, Oscar García-García, Mar O’Callaghan, Ainhoa Pascual-Alonso, Judith Armstrong, MDS Group, Antonio F. Martinez-Monseny

“…Recurrent respiratory infections (79%), dysphagia (73%), constipation (73%) and gastroesophageal reflux (57%) were common. Seizures occurred in 53%, with 33% being treatment-refractory. …”
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Acute Neurotoxicity in Children Treated for Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma: A 10-Year Single-Centre Experience by Izabela Kranjčec, Nada Rajačić, Tamara Janjić, Monika Kukuruzović, Filip Jadrijević-Cvrlje, Maja Pavlović, Jelena Roganović

“…The most frequent clinical presentation was seizures (83.3%), with status epilepticus in four cases. …”
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Multidisciplinary, multicenter consensus for the care of patients affected with Sturge–Weber syndrome by May El Hachem, Andrea Diociaiuti, Angela Galeotti, Francesca Grussu, Elena Gusson, Alessandro Ferretti, Carlo Efisio Marras, Davide Vecchio, Simona Cappelletti, Mariasavina Severino, Carlo Gandolfo, Simone Reali, Rosa Longo, Carmen D’Amore, Lodovica Gariazzo, Federica Marraffa, Marta Luisa Ciofi Degli Atti, Maria Margherita Mancardi, and the Sturge-Weber Syndrome Multidisciplinary Group

“…The spectrum of clinical manifestations includes headache, seizures, stroke-like events, intellectual disability, glaucoma, facial asymmetry, gingival hyperplasia, etc. …”
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A rare case of adult-onset vanishing white matter leukoencephalopathy with movement disorder, expressing homozygous EIF2B3 and PRKN pathogenic variants by Bashar Kamal Ali Douden, Yazan Mohammad Abdullah Abufara, Mahmood Fayez Ali Aldrabeeh, Naela Ramadan Mohammad Tell, Ismail Abudaya

“…It is typified by a gradual loss of white matter in the brain and spinal cord, which results in impairments in vision and hearing, cerebellar ataxia, muscular weakness, stiffness, seizures, and dysarthria cogitative decline. Many reports involve minors. …”
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Translation, adaptation and validation of an epilepsy screening instrument in two Ghanaian languages. by Emmanuel Kwame Darkwa, Sabina Asiamah, Elizabeth Awini, Cynthia Sottie, Anthony Godi, John E Williams, Albert Akpalu, J Helen Cross, Josemir W Sander, Arjune Sen, Charles R Newton, Anthony Danso-Appiah, Patrick Adjei

“…We included questions that could identify convulsive and non-convulsive seizures. Language experts forward- and back-translated the questionnaires into the two languages: Asante Twi and Dangme. …”
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The sphingosine‐1‐phosphate signaling pathway (sphingosine‐1‐phosphate and its receptor, sphingosine kinase) and epilepsy by Lin Wang, Qingxia Kong, Xinyi Leng, Howan Leung, Yang Li

“…The brains of people with epilepsy exhibit a pathological and persistent propensity for recurrent seizures. Epilepsy often coexists with cardiovascular disease, cognitive dysfunction, depression, etc., which seriously affects the patient's quality of life. …”
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<i>Toxoplasma gondii</i> and Rabies—The Parasite, the Virus, or Both? by Ragan Wilson, Shannon Caseltine, Edith Will, Jeremiah Saliki, Ruth C. Scimeca

“…Anamnesis in some of the <i>T. gondii</i>-positive samples included ataxia, aggression, muscle rigidity, lethargy, and seizures, with the latter also described in dogs and aggression in the positive bovine sample. …”
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Analgesia and sedation strategies in neonates undergoing whole-body therapeutic hypothermia: A scoping review. by Mahima Joshi, Javed Muneer, Lawrence Mbuagbaw, Ipsita Goswami

“…Dexmedetomidine has additional benefits of thermal tolerance, neuroprotection, faster recovery, and less likelihood of seizures. There is a wide inter-individual variability in serum drug levels due to the impact of temperature, end-organ dysfunction, postnatal age, and body weight on drug metabolism.…”
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Burden of pertussis in infants in the Eastern Mediterranean Region and the impact of maternal vaccination: a systematic review by Randa K. Saad, Yousef Khader, Flor M. Munoz, Faris Lami, Ezzeddine Mohsni, Nadine Haddad

“…High hospitalization rates and severe complications, including seizures and the need for ventilatory support, were frequently reported in infants < 6 months of age. …”
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