An Unexpected Presentation of Serotonin Syndrome in a Patient Receiving ECT by Shahzaib Khan, Breanna Wennberg, Malgorzata Witkowska, Jacob Rattin, Raunak Khisty

“…Serotonin syndrome is a toxidrome consisting of autonomic instability, altered mentation, hyperreflexia, clonus, and seizures. It is suspected to be due to either elevated serotonin concentrations or overstimulation of 5-hydroxytryptamine (5-HT) receptors. …”
Get full text

Secondary bilateral synchronization of interictal EEG discharges in focal epilepsy: prevalence and associated factors by Polina Specktor, Ronen Spierer, Mark Katson, Moshe Herskovitz, Moshe Herskovitz

“…They also had higher rates of unclear seizure onset zone and focal to bilateral tonic–clonic seizures. …”
Get full text

Microfluidic Cultures of Basal Forebrain Cholinergic Neurons for Assessing Retrograde Cell Death by Live Imaging by Srestha Dasgupta, Mansi Pandya, Wilma Friedman

“…Levels of these trophic factors may be modulated in the BFCN axon or soma microenvironment under neurodegenerative conditions such as seizure and brain injury. In this protocol, BFCNs are established in microfluidic devices for compartmental culture, with the aim of studying the effects of axon- or soma-specific stimulation of BFCNs for an in vitro representation of distal axon vs. soma environments as seen in vivo. …”
Get full text

Memory Functioning in Children with Epilepsy: Frontal Lobe Epilepsy, Childhood Absence Epilepsy, and Benign Epilepsy with Centrotemporal Spikes by Ana Filipa Lopes, José Paulo Monteiro, Maria José Fonseca, Conceição Robalo, Mário Rodrigues Simões

“…In addition, type of epilepsy, earlier age at epilepsy onset, and longer active duration of epilepsy were associated with memory problems. Seizure frequency and treatment, however, did not influence memory performance. …”
Get full text

Porphyric encephalopathy in a 15-year-old girl: A case report by Saihari S Dukkipati, Jordan Terschluse, Drew Thodeson, Angela Beavers, Melissa Muff-Luett, Claire Ives, Sookyong Koh

“…A 15-year-old girl presented with new onset tonic-clonic seizures, encephalopathy, abdominal pain, and hypertension with a history of weight loss and emesis. …”
Get full text

Knowledge and attitude on epilepsy among neurology patients and their attendants: Mixed methods research at a tertiary hospital by S. Ramesh Kannan, R. Rajalakshmi, Varun Babu, Kandasamy Ravichandran

“…This could be due to misconceptions of the public on witnessing an epileptic seizure. Hence, the current study evaluated knowledge, attitude, and perception of neurology outpatient department and inpatients and their caregivers, at the tertiary care hospital in South India. …”
Get full text

Acute cerebral edema: a lethal neurological complication in a patient with COVID-19 infection. Case report and literature review by M. Puodžiūnaitė, R. Sadeckaitė, A. Čikotienė

“…A few days later, he developed worsening respiratory function with an acute seizure episode. Head CT scan revealed subarachnoid hemorrhage with diffuse cerebral edema as a lethal neurological complication, possibly secondary to COVID-19. …”
Get full text

Hashimoto’s Encephalopathy Presenting with Unusual Behavioural Disturbances in an Adolescent Girl by Murugan Selvaraj Karthik, Kulothungan Nandhini, Viswanath Subashini, Ramasamy Balakrishnan

“…Here we are reporting a case of HE in a 19-year-old girl who presented with seizure-like episodes, confusion, and behavioural disturbances with catatonic symptoms such as posturing, echopraxia, echolalia, and ambivalence. …”
Get full text

Atorvastatin-Diltiazem Combination Induced Rhabdomyolysis Leading to Diagnosis of Hypothyroidism by N. D. B. Ehelepola, S. M. B. Y. Sathkumara, H. M. P. A. G. S. Bandara, K. L. R. Kalupahana

“…On examination muscle tenderness was noticed and creatine kinase levels indicated rhabdomyolysis which we attributed to atorvastatin. Patient developed a seizure and myoclonus of masseters. Considering this, his confusion and his neutrophilia and high C-reactive protein levels, empirical antibiotics with dexamethasone were started and the patient responded to that. …”
Get full text

The Effect of long-term rapamycin administration on intracellular calcium quantification and RhoA activity in kainic acid epilepsy model by Machlusil Husna, Kusworini Handono, Hidayat Sujuti, Aulanni’am Aulanni’am, Rumman Karimah, Afiyfah Kiysa Waafi, Alya Satira

“…This shows that there is still a need for novel anti-seizure medication that have different mechanisms. …”
Get full text

Induced Neurocysticercosis in Rhesus Monkeys (Macaca mulatta) Produces Clinical Signs and Lesions Similar to Natural Disease in Man by N. Chowdhury, A. Saleque, N. K. Sood, L. D. Singla

“…Neurocysticercosis is a serious endemic zoonosis resulting in increased cases of seizure and epilepsy in humans. The genesis of clinical manifestations of the disease through experimental animal models is poorly exploited. …”
Get full text

Too Aggressive Drop in Blood Pressure in a Hypertensive Male Leading to “Man-in-the-Barrel Syndrome” by Chamara Dalugama, Achila Jayasinghe, Udaya Ralapanawa, Shamali Abeygunawardena, Thilak Jayalath

“…A 75-year-old Sri Lankan male presented following a generalized tonic-clonic seizure to a tertiary care hospital. Upon recovery, he was noted to have severe brachia diplegia affecting shoulder movements with preserved hand muscle power and motor functions of the lower limb. …”
Get full text

Congenital Oligodendroglioma: Clinicopathologic and Molecular Assessment with Review of the Literature by Hope Richard, Kimberly Stogner-Underwood, Christine Fuller

“…The patient initially presented at 3 months of age with symptoms suspicious for seizure. Initial workup including electroencephalography (EEG), electrocardiogram (EKG), and computed tomography (CT) of the head was negative. …”
Get full text

A Potential Role for Felbamate in TSC- and NF1-Related Epilepsy: A Case Report and Review of the Literature by Natanya M. Mishal, Dimitrios Arkilo, Ju Tang, John R. Crawford, Sonya G. Wang

“…A 15-year-old girl with maternal inheritance of neurofibromatosis type 1 (NF1) and paternal inheritance of tuberous sclerosis complex (TSC) developed intractable epilepsy at age 5. Her seizures were refractory to adequate doses of four antiepileptic medications until felbamate was initiated at age 7. …”
Get full text

Analytical Methods Used for the Detection and Quantification of Benzodiazepines by Zidane Qriouet, Zineb Qmichou, Nadia Bouchoutrouch, Hassan Mahi, Yahia Cherrah, Hassan Sefrioui

“…Indeed, the BZDs have been used in different therapeutic areas including insomnia, anxiety, seizure disorders, or general anesthesia. Unfortunately, these drugs are present in the illegal street market, leading to a lot of drug abuse amongst some addicted users, road insecurity, and suicide. …”
Get full text

Case Report of RANBP2 Mutation and Familial Acute Necrotizing Encephalopathy by Mohamad Paktinat, Kamran Hessami, Soroor Inaloo, Hamid Nemati, Pegah Katibeh, Marzieh Nejabat, Mohammad Hassan Darabi, Ali Hosseini Bereshneh

“…They all presented with seizure and decreased level of consciousness. Unlike the siblings, the cousin eventually expired mainly due to the delay in diagnosis, resulting from late presentation of typical brain involvements of ANE in magnetic resonance imaging (MRI). …”
Get full text

Bone within bone as a calcified chronic extra-dural hematoma mimicking ossified chronic subdural hematomas: a rare case report in pediatric patients by Mohan Karki, Yam Bahadur Roka, Abhinash Jha

“…Case Presentation We report a case of 10-year-old female who presented in emergency department with complaints of headache, repeated attacks of seizure, disorientation and sudden loss of consciousness for 2 days. …”
Get full text

Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia by Megumi Andoh, Natsuki Shinoda, Yusuke Taira, Tasuku Araki, Yuka Kasahara, Haruki Takeuchi, Masayuki Miura, Yuji Ikegaya, Ryuta Koyama

“…Furthermore, activity-dependent caspase-3 activation at inhibitory presynapses induces microglial phagocytosis in mice and increases seizure susceptibility. This increased susceptibility is reversed by genetic depletion of microglial complement receptors. …”
Get full text

Amphetamine Positive Urine Toxicology Screen Secondary to Atomoxetine by Joshua L. Fenderson, Amy N. Stratton, Jennifer S. Domingo, Gerald O. Matthews, Christopher D. Tan

“…An otherwise healthy 27-year-old female with a history of attention deficit hyperactivity disorder (ADHD) treated with atomoxetine had an acute onset tonic-clonic seizure. On arrival to the hospital, a urine toxicological drug screen with immunochemical cloned enzyme donor immunoassay (CEDIA) was performed. …”
Get full text

Temporary Access to Documents Containing Medical Secrecy (Criminal Procedural Aspect) by S. Y. Ablamskyi, V. V. Romaniuk

“…Particular attention has been paid to the fact that the seizure of documents containing information that may constitute medical secrecy should be carried out only through the temporary access to them. …”
Get full text