Distinct sex differences in ethanol consumption and operant self-administration in C57BL/6J mice with uniform regulation by glutamate AMPAR activity by Sara Faccidomo, Sara Faccidomo, Vallari R. Eastman, Taruni S. Santanam, Katarina S. Swaim, Seth M. Taylor, Clyde W. Hodge, Clyde W. Hodge

“…Acute sensitivity to EtOH sedation and blood clearance were evaluated as potential modifying factors. …”
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Cross-referencing French hematology teams’ knowledge and perception of end-of-life situations: a national mixed-methods survey by Chloé Prod’homme, Côme Bommier, Laurène Fenwarth, Stephane Moreau, Alice Polomeni

“…The average score for identifying complex situations was 7.1 out of 10 (IQR 5.7,8.6), with lesser knowledge of situations involving double effect, euthanasia and sedation for distress than of situations involving limiting or stopping treatment. …”
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Electroencephalography Correlation of Ketamine-induced Clinical Excitatory Movements: A Systematic Review by Emine M. Tunc, Neil Uspal, Lindsey Morgan, Sue L. Groshong, Julie C. Brown

“…Background: This is a systematic review investigating the correlation between seizures identifiable on electroencephalogram (EEG), clinical excitatory movements (CEM), and ketamine administration for procedural sedation. Methods: We searched MEDLINE, EMBASE, Cochrane CENTRAL, and Web of Science in April 2021. …”
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Colon Capsule Endoscopy: Review and Perspectives by David Friedel, Rani Modayil, Stavros Stavropoulos

“…Colon capsule endoscopy utilizing PillCam COLON 2 capsule allows for visualization potentially of the entire colon and is currently approved for patients who cannot withstand the rigors of traditional optical colonoscopy (OC) and associated sedation as well as those that had an OC that was incomplete for technical reasons other than a poor preparation. …”
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Canadian Association of Gastroenterology Indicators of Safety Compromise following Colonoscopy in Clinical Practice by Mark R. Borgaonkar, David Pace, Muna Lougheed, Curtis Marcoux, Bradley Evans, Nikita Hickey, Meghan O’Leary, Jerry McGrath

“…The most common adverse events were mild and sedation related. Rates of serious adverse events were in keeping with published reports.…”
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Study on the Analgesic Efficacy of Femoral Nerve Block for Post-Hip Arthroscopy Pain by Mengwen Xue, Li Zhang, Ruiping Bai, Rui An, Jiarui Li, Xin Shen

“…Secondary outcomes included total intraoperative dexmedetomidine consumption, RASMAY sedation scores, and patients’ satisfaction scores postoperatively. …”
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Persistent Paradoxical Reaction to Midazolam despite General Anesthesia with Dexmedetomidine by Sarah Park, Mariam Ibrahim, Augusto Torres

“…Midazolam is a widely used benzodiazepine due to its rapid onset of action and relatively safe side effect profile. It is used for sedation, anxiolysis, and induction of general anesthesia. …”
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Successful Closed Reduction of a Lateral Elbow Dislocation by Kenya Watanabe, Takuma Fukuzawa, Katsuhiro Mitsui

“…The reduction can be hindered by swelling and soft tissue interposition, and we describe the use of a nonoperative reduction technique performed under mild sedation with early physiotherapy to avoid joint stiffness. …”
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Ketamine Boluses Are Associated with a Reduction in Intracranial Pressure and an Increase in Cerebral Perfusion Pressure: A Retrospective Observational Study of Patients with Sever... by Bradley A. Dengler, Oliver Karam, Colleen A. Barthol, Aaron Chance, Laura E. Snider, Clare M. Mundy, Michael T. Bounajem, William C. Johnson, Moustafa M. Maita, Paola M. Mendez-Gomez, Ali Seifi, Shaheryar Hafeez

“…Increased intracranial pressure (ICP) and hypotension have long been shown to lead to worse outcomes in the severe traumatic brain injury (TBI) population. Adequate sedation is a fundamental principle in TBI care, and ketamine is an attractive option for sedation since it does not commonly cause systemic hypotension, whereas most other sedative medications do. …”
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Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel Indication by Fahad Javed, Alexandre Miguel Benjo, Kiran Reddy, Muhammad Shoaib Akram, Shahzeb Afsar Khan, Manpreet Singh Sabharwal, Girish Nadkarni, Emad F. Aziz, Eyal Herzog

“…Worth mentioning is the use of an alpha-2 receptor selective agonist named Dexmedetomidine as a treatment modality to control hypertension in this patient, which is approved only for sedation of intubated and mechanically ventilated patients in the intensive care settings and for sedation during invasive procedures. …”
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Circulatory Collapse due to Hyperinflation in a Patient with Tracheobronchomalacia: A Case Report and Brief Review by Niclas Lundström, Gert Henriksson, Ola Börjesson, Malin Jonsson Fagerlund, Johan Petersson

“…Adjusted ventilation settings, deep sedation, and muscle paralysis followed by acute stenting of the affected collapsing airways restored ventilation and prevented recurrent circulatory collapse. …”
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A Novel Use of Liposomal Bupivacaine in Erector Spinae Plane Block for Pediatric Congenital Cardiac Surgery by Stylianos Voulgarelis, Gregory M. Halenda, Justinn M. Tanem

“…The perioperative course of all patients was remarkable for low pain and sedation scores, especially after chest tube removal. …”
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Analysis of Hospital Discharge Data to Characterize Obstructive Sleep Apnea and Its Management in Adult Patients Hospitalized in Canada: 2006 to 2007 by Kathy F Spurr, Debra L Morrison, Michael A Graven, Adam Webber, Robert W Gilbert

“…Compliance with this treatment is especially important in OSA patients experiencing concomitant acute and chronic disease or illness, and those undergoing procedures associated with sedation, analgesia and anesthesia.…”
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Airway Management for Massive Anterior Mediastinal Tumor Resection in an Infant: A Strategy Involving Spontaneous Breathing-Preserving Endotracheal Intubation under Intravenous Ane... by Hiromi Matsuda, Ei Ito, Akiko Katsuike, Hirotsugu Okamoto

“…Tracheal intubation under sedation in uncooperative infants is challenging. The case of a 4-month-old infant with a massive anterior mediastinal tumor and upper respiratory tract symptoms, for whom effective preoxygenation was provided with a high-flow nasal cannula (HFNC), allowing for safe tracheal intubation in combination with a supraglottic device and local anesthetic, is reported. …”
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Comparison of Nasopharyngeal Airway with Endoscopic Respiratory Mask for Hypoxemia in Painless Gastrointestinal Endoscopy in Obese Outpatients: Study Protocol for a Randomized Cont... by Xiang D, Deng L, Zhou R, Zhang X, Tian L, Jiang W, Zhou Y, Chen W, Peng Y

“…All patients in two groups will receive propofol and opioids for procedural sedation. The primary outcome will be the incidence of hypoxemia. …”
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Injection of Botulinum Toxin a to Upper Esophageal Sphincter for Oropharyngeal Dysphagia in Two Patients with Inclusion Body Myositis by Louis WC Liu, Mark Tarnopolsky, David Armstrong

“…This report presents the first documentation of botulinum toxin A injection into the upper esophageal sphincter using a flexible esophagogastroduodenoscope under conscious sedation, to reduce upper esophageal sphincter pressure and successfully alleviate oropharyngeal dysphagia in two IBM patients.…”
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Sudden Tracheal Collapse during EGD and Subsequent Anesthetic Management with Dexmedetomidine-Ketamine in a Patient with Achalasia and Tracheomalacia by Joshua H. Atkins, Jeff E. Mandel, David C. Metz

“…Physiology of airway obstruction with forced breathing maneuvers is discussed along with the potential advantages of dexmedetomidine-ketamine sedation for management of patients with achalasia undergoing outpatient endoscopic procedures.…”
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Asystole after Orthotopic Lung Transplantation: Examining the Interaction of Cardiac Denervation and Dexmedetomidine by Christopher Allen-John Webb, Paul David Weyker, Brigid Colleen Flynn

“…Dexmedetomidine is an α2-receptor agonist commonly used for sedation and analgesia in ICU patients. Dexmedetomidine is known to provide sympatholysis and also to have direct atrioventricular and sinoatrial node inhibitory effects. …”
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Ultrasound-guided low-volume anterior suprascapular nerve block for reduction of anterior shoulder dislocation in the emergency department: A case series by Chitta Ranjan Mohanty, Anju Gupta, Rakesh Vadakkethil Radhakrishnan, Neha Singh, Saroj Kumar Patra

“…Anterior shoulder dislocation (ASD) is the most common type of dislocation presented to the emergency department (ED) with severe pain and limitation of range of movement. Procedural sedation and analgesia are commonly used for ASD, but regional techniques are gaining popularity. …”
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Foreign Body Aspiration of a Dental Bridge in the Left Main Stem Bronchus by Monay Mahmoud, Syed Imam, Hetalben Patel, Matthew King

“…Decreased levels of consciousness, sedation, and neuromuscular diseases are major risk factors for foreign body aspiration in adults. …”
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