Eggshell Based Nano-Engineered Hydroxyapatite and Poly(lactic) Acid Electrospun Fibers as Potential Tissue Scaffold by Vitus A. Apalangya, Vijaya K. Rangari, Boniface J. Tiimob, Shaik Jeelani, Temesgen Samuel

“…The stained confocal optical images indicated the secretion of cytoplasmic extension linking adjoining nuclei after 96 hours of incubation. …”
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The pathogenesis of COVID-19: Hypercoagulation and D-dimer in thrombotic complications by Leonid DUBEY, Halyna LYTVYN, Olha DOROSH, Nataliya DUBEY, Olena KOZLOVA, Michal PRUC, Nina KUBIKOWSKA, Lukasz SZARPAK, Kavita BATRA, Francesco CHIRICO, Gabriella NUCERA, Svitlana DOAN, Uljana SHEVTSIV

“…In addition, plasmin is involved in the pathophysiology of acute respiratory distress syndrome (ARDS) in SARS and promotes the secretion of cytokines, such as IL-6 and TNF, from activated macrophages. …”
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Fungal-Host Interaction: Curcumin Modulates Proteolytic Enzyme Activity of Candida albicans and Inflammatory Host Response In Vitro by Emily Chen, Bruna Benso, Dalia Seleem, Luiz Eduardo Nunes Ferreira, Silvana Pasetto, Vanessa Pardi, Ramiro Mendonça Murata

“…Biofilm formation was quantified and the proteinase and phospholipase secretion was measured. The cytotoxicity was tested in oral fibroblast cells. …”
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ATP-Binding Pocket-Targeted Suppression of Src and Syk by Luteolin Contributes to Its Anti-Inflammatory Action by Jeong-Oog Lee, Deok Jeong, Mi-Yeon Kim, Jae Youl Cho

“…Luteolin dose-dependently inhibited the secretion of nitric oxide (NO) and prostaglandin E2 (PGE2) and diminished the levels of mRNA transcripts of inducible NO synthase (iNOS), tumor necrosis factor- (TNF-) α, and cyclooxygenase-2 (COX-2) in lipopolysaccharide- (LPS-) and pam3CSK-treated macrophage-like RAW264.7 cells without displaying cytotoxicity. …”
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Development of a Novel Biosensor Using Cationic Antimicrobial Peptide and Nickel Phthalocyanine Ultrathin Films for Electrochemical Detection of Dopamine by Maysa F. Zampa, Inês Maria de S. Araújo, José Ribeiro dos Santos Júnior, Valtencir Zucolotto, José Roberto de S. A. Leite, Carla Eiras

“…The antimicrobial peptide dermaseptin 01 (DS 01), from the skin secretion of Phyllomedusa hypochondrialis frogs, was immobilized in nanostructured layered films in conjunction with nickel tetrasulfonated phthalocyanines (NiTsPc), widely used in electronic devices, using layer-by-layer technique. …”
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Lactiplantibacillus plantarum improves the growth performance and meat quality of broilers by regulating the cecal microbiota and metabolites by Yu Liu, Zhisheng Wang, Wenshuo Xi, Junmeng Yuan, Kai Zhang, Huawei Liu, Jinshan Zhao, Yang Wang

“…Functional prediction of the gut microbiota indicated that pathways, including pancreatic secretion and spliceosome were enriched by the Lp treatments. …”
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Overexpression of microRNA-211 in Functional Dyspepsia via Downregulation of the Glial Cell Line-Derived Neurotrophic Factor (GDNF) by Increasing Phosphorylation of p38 MAPK Pathwa... by Jue Wang, Sai Gu, Bo Qin

“…Transfection with miR-211 mimics significantly decreased GDNF mRNA expression and protein secretion (p<0.001). An inhibited intestinal epithelial cell wound healing (p<0.05) and increased expression levels of phosphorylated p38 MAPK (p<0.05) were found in IECs cultured with medium from EGCs transfected with miR-211 mimics. …”
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Isolation and characterization of a highly pathogenic strain of Vibrio harveyi EFL-2201 from pearl gentian grouper by Biao Yuan, Zhixia Zhuang, Xiaoru Wang, Huabin Huang, Qingpi Yan

“…Whole-genome sequencing of the strain revealed that mechanisms related to adhesion, secretion, toxins, and invasion significantly contributed to its pathogenicity. …”
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Unraveling Ferroptosis: A New Frontier in Combating Renal Fibrosis and CKD Progression by Rui Jin, Yue Dai, Zheng Wang, Qinyang Hu, Cuntai Zhang, Hongyu Gao, Qi Yan

“…This results in maladaptive repair mechanisms and the secretion of profibrotic factors, and exacerbates renal fibrosis. …”
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A study on blocking store-operated Ca2+ entry in pulmonary arterial smooth muscle cells with xyloketals from marine fungi by Zhou Jie-Bin, Sun Ying-Ying, Zheng Ying-Lin, Yu Chu-Qin, Lin Hua-Qing, Pang Ji-Yan

“…The results showed that xyloketal A (1), an unusual ketal with C-3 symmetry, exhibited strong SOCE blocking activity. Secretion of interleukin-8 (IL-8) was also inhibited by xyloketal A. …”
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Involvement of circRNAs in Proinflammatory Cytokines-Mediated β-Cell Dysfunction by Zhen Wang, Chao Deng, Ying Zheng

“…As little is known about their role in insulin-secreting cells, this study is aimed at evaluating their contribution in the process of inflammation-induced β-cell damage. …”
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The injectable hydrogel loading cannabidiol to regulate macrophage polarization in vitro for the treatment of chronic enteritis by Ye Wang, Xingming Ji, Xinyi Wang, Mengyu Sun, Cheng Li, Dongmei Wu

“…Conclusion: The vitro experiments have confirmed that the CBD-loaded hydrogel system has good biosafety, and can alleviate inflammation by regulating the polarization direction of macrophages, and then inhibiting the secretion of pro-inflammatory factors, laying a strong foundation for the treatment of chronic enteritis.…”
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IL-1β-Induced Matrix Metalloprotease-1 Promotes Mesenchymal Stem Cell Migration via PAR1 and G-Protein-Coupled Signaling Pathway by Ming-Siou Chen, Cheng-Yu Lin, Yun-Hsuan Chiu, Chie-Pein Chen, Pei-Jiun Tsai, Hwai-Shi Wang

“…In conclusion, IL-1β promotes the secretion of MMP-1, which then activates the PAR1 and G-protein-coupled signal pathways to promote mesenchymal stem cell migration.…”
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Cytokine and eicosanoid regulation by Schistosoma mansoniduring LSE penetration by A. C. Fusco, B. Salafsky, T. Shibuya

“…TNFα was not detected. Secreted IL-1α levels were (mean ± S.E.M. (n)): Control, 1.03 ng ± 0.15 (11); IFNγ 1.90 ng ± 0.48 (5); cercariae, 1.79 ng ± 0.22 (22). …”
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Meta-analysis of RNA-Seq datasets allows a better understanding of P. tricornutum cellular biology, a requirement to improve the production of Biologics by Isabelle Boulogne, Charlotte Toustou, Muriel Bardor

“…Therefore, the expression of genes involved in the N-glycan biosynthesis, protein export and secretion, protein quality control and proteasome, as well as those encoding proteases were analyzed and compared. …”
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CYP1A1 Relieves Lipopolysaccharide-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells by Wen-Yao Zhang, Hao Wang, Shaopei Qi, Xixi Wang, Xueru Li, Kun Zhou, Yong Zhang, Ming-Qing Gao

“…Overexpression of CYP1A1 in bovine mammary epithelial cells alleviated the LPS-induced inhibition of epithelial proliferation, abated the LPS-induced increase of gene expression and protein secretion of inflammatory cytokine tumor necrosis factor-α and interleukin-6, and attenuated the LPS-induced activation of NF-κB signaling. …”
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Efficacy of Human-Recombinant Epidermal Growth Factor Combined with Povidone-Iodine for Pressure Ulcers and Its Influence on Inflammatory Cytokines by Zunjiang Zhao, Dalun Lv, Baode Zhang, Liu Yong, Rongtao Zhang, Xiukun Wang

“…It can promote PU alleviation and hydroxyproline secretion in the wound and inhibit pain and inflammatory reactions, which is worthy of clinical promotion.…”
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Structural characterization and immunostimulatory activity of a water-soluble polysaccharide from abalone (Haliotis discus hannai Ino) muscle by Linfan Shi, Gengxin Hao, Jun Chen, Junling Wang, Wuyin Weng

“…In addition, AMPP was found to possess potent immunostimulatory activity via rising phagocytosis of RAW264.7 cells and promoting secretion of TNF-α.…”
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Establishment of subcutaneous transplantation platform for delivering induced pluripotent stem cell-derived insulin-producing cells. by Hong Thuan Tran, Watchareewan Rodprasert, Irma Padeta, Saranyou Oontawee, Steven Dwi Purbantoro, Anatcha Thongsit, Parkpoom Siriarchavatana, Sayamon Srisuwatanasagul, Hiroshi Egusa, Thanaphum Osathanon, Chenphop Sawangmake

“…Further double encapsulation of mGF-iPSC-derived IPCs (mGF-iPSC-IPCs) could preserve the insulin secretion capacity and the transplantation potential of the generated IPCs. …”
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SPERM QUALITY IN RATS PREDISPOSED TO THE MANIFESTATION OF CATATONIC REACTIONS by M. A. Kleshchev, T. A. Alekhina, L. V. Osadchuk

“…It has been assumed that the changes of spermatogenic parameters in response to selection for catatonia are caused by changing the ontogenic pattern of testosterone secretion. In conclusion, the hereditary predisposition to catatonic reaction is associated with impaired sperm parameters in adult rats that reduces their chance to reproduction. …”
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