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861
The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus Individuals
Published 2022-09-01“…Diabetes mellitus can cause damage to multiple organ systems, leading to the development of severe and life-threatening health issues, due to decreased insulin secretion, resistance to peripheral insulin effects, or both. …”
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862
Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascu...
Published 2016-01-01“…Glucose stimulated islet-containing constructs displayed reduced insulin secretion compared to islets alone. However, labeling for insulin post-glucose stimulation revealed that the constructs expressed abundant levels of insulin. …”
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863
The association between melatonin hormone and reproductive hormones in polycystic ovary syndrome: A case–control study
Published 2024-01-01“…It is related to androgen disturbance, obesity, and irregular menstrual cycle. Pineal gland secretes melatonin hormone, which is involved in the regulation of the circadian rhythm. …”
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864
Hepatitis B e Antigen Seroconversion Is Related with the Function of Dendritic Cells in Chronic Hepatitis B Virus Infection
Published 2014-01-01“…DC from patients in immune tolerance showed a remarkably lower surface expression of CD80, CD86, and HLA-DR and exhibited an impaired stimulatory capacity in MLR and reduced secretion of IL-12, as compared to the patients in inactive HBsAg carrier state. …”
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865
Cellular Anti-Inflammatory and Antioxidant Activities of Bamboo Sasa albomarginata Leaf Extract and Its Constituent Coumaric Acid Methyl Ester
Published 2022-01-01“…To elucidate the mechanism of in vivo activity, we have studied the cellular anti-inflammatory and antioxidant activities of the extract and its constituents. Methods. Secretion of mouse and human IL-6 was measured by ELISA. …”
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866
Posttranscriptional Suppression of Lipopolysaccharide-Stimulated Inflammatory Responses by Macrophages in Middle-Aged Mice: A Possible Role for Eukaryotic Initiation Factor 2α
Published 2014-01-01“…Although LPS-stimulated secretion of tumor necrosis factor-α (TNF-α) by the macrophages from middle-aged mice was significantly lower than that from young mice, LPS caused marked increases in levels of TNF-α mRNA in macrophages from middle-aged as well as young mice. …”
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867
Evaluation of Retinal Pigment Epithelial Cell Cytotoxicity of Recombinant Tissue Plasminogen Activator Using Human-Induced Pluripotent Stem Cells
Published 2019-01-01“…RPE function was evaluated by measuring the secretion of pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) and RPE-specific gene expression. …”
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868
2′-Fucosyllactose as a prebiotic modulates the probiotic responses of Bifidobacterium bifidum
Published 2025-01-01“…The growth inhibition of 2′-FL on the Cronobacter strains was mediated by promoting the secretion of antibacterial substances from B. bifidum. …”
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869
Osteogenic differentiation of mesenchymal stem cells in cell-laden culture of self-assembling peptide hydrogels
Published 2025-03-01“…Our results demonstrate that the Fmoc-FF 3D cultures significantly enhanced osteogenic differentiation, as evidenced by increased calcium deposition, elevated phosphatase activity, and the secretion of osteocalcin. We propose that the peptides provide integrin-binding sites that activate a cytoplasmic feedback loop essential for differentiation. …”
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870
Investigation of some anaerobic bacteria in the sputum of cystic fibrosis patients and healthy people in Tehran, Iran
Published 2024-07-01“…Background: In Cystic Fibrosis (CF) patients, increased mucus secretion and accumulation due to genetic defect leads to decreased oxygen levels and colonization of anaerobic bacteria. …”
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871
Metabolic rate and insulin-independent glucose uptake increase in a TDP-43Q331K mouse model of amyotrophic lateral sclerosis
Published 2025-02-01“…At the later stages of disease, heightened glucose uptake was observed despite unchanged insulin secretion or tolerance, indicating mechanisms independent of insulin. …”
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872
High Doses of Caffeine during the Peripubertal Period in the Rat Impair the Growth and Function of the Testis
Published 2015-01-01“…Our results demonstrate that peripubertal caffeine consumption can interfere with the maturation and function of the testis, possibly by interrupting endogenous testosterone secretion and reducing the sensitivity of Leydig cells to gonadotrophic stimulation. …”
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873
Diabetes Mellitus in Outpatients in Debre Berhan Referral Hospital, Ethiopia
Published 2016-01-01“…Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Most people with diabetes live in low- and middle-income countries and these will experience the greatest increase in cases of diabetes over the next 22 years. …”
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874
The Anti-Inflammatory Effect of Callicarpa nudiflora Extract on H. Pylori-Infected GES-1 Cells through the Inhibition of ROS/NLRP3/Caspase-1/IL-1β Signaling Axis
Published 2022-01-01“…CN can also inhibit the secretion of inflammatory factors, such as TNF-α, IL-1β, IL-6, and IL-8. …”
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875
Association of Glycemic Indices (Hyperglycemia, Glucose Variability, and Hypoglycemia) with Oxidative Stress and Diabetic Complications
Published 2020-01-01“…In particular, hyperglycemia promotes the creation of advanced glycation end-products (AGEs), the activation of protein kinase C (PKC), and the hyperactivity of hexosamine and sorbitol pathways, leading to the development of insulin resistance, impaired insulin secretion, and endothelial dysfunction, by inducing excessive ROS production and OS. …”
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876
Effect of Different Nutritional Materials on Laccase Activity and Biomass Accumulation of the Auricularia cornea var. Li Strain
Published 2025-01-01“…Li and identified culture substances that were beneficial for laccase secretion during different growth stages of the mushroom. …”
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877
Innovation of kwetiau with red rice and red bean flour: evaluation of nutritional value and potential fiber source for patients with diabetes mellitus
Published 2025-02-01“… Diabetes mellitus is characterized by hyperglycemia and metabolic dysfunctions in carbohydrates, fats, and proteins, primarily due to impaired insulin action and/or secretion. Dietary fiber can help delay carbohydrates conversion to glucose, slow the rise in blood sugar, and aid in blood sugar regulation. …”
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878
Bacteriological Profile and Antibiotic Susceptibility Patterns in Lower Respiratory Tract Infection at a Tertiary Care Teaching Hospital
Published 2025-02-01“…A total of 1943 respiratory samples (1709 sputum, 211 ET secretions and 23 BAL) were received during the study period. 669 sputum samples (39.14%), 102 ET secretion (48.34%) and 2 BAL fluid (8.69%) were positive for bacterial isolates. …”
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879
Proteomic Analysis of Saliva Identifies Potential Biomarkers for Orthodontic Tooth Movement
Published 2012-01-01“…These processes trigger the secretion of various proteins and enzymes into the saliva. …”
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880
Preferential Th1 Cytokine Profile of Phosphoantigen-Stimulated Human Vγ9Vδ2 T Cells
Published 2010-01-01“…Addition of IL-2 or IL-15 caused expansion of IFN-γ-producing Vγ9Vδ2 T cells, but did not enhance IFN-γ secretion after 24–72 hours. Thus, phosphoantigen-stimulated Vγ9Vδ2 T cells have potential as Th1-biasing adjuvants for immunotherapy.…”
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