The Association of the Phylogenetic Typing of the Klebsiella pneumoniae Isolates with Antibiotic Resistance by Shabnam Baghbanijavid, Hossein Samadi Kafil, Safar Farajniya, Seyed Reza Moaddab, Hasan Hosainzadegan, Fatemeh Yeganeh Sefidan, Mojtaba Varshouchi, Hamed Ebrahimzadeh Leylabadlo, Reza Ghotaslou

“…A total of 100 KPC isolates were obtained from the clinical specimens (urine, respiratory secretion, blood, wounds, and trachea). The enrolled patients included 47 men and 53 women aged from 1 to 91 years old. …”
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Antigen Gene Transfer to Human Plasmacytoid Dendritic Cells Using Recombinant Adenovirus and Vaccinia Virus Vectors by Hetty J. Bontkes, Janneke J. Ruizendaal, Marco W. J. Schreurs, Duco Kramer, Chris J. L. M. Meijer, Erik Hooijberg

“…Plasmacytoid dendritic cells (PDC) play a role in the innate immune response to viral infections through the secretion of IFNα but may also play a role in specific T-cell induction. …”
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Immunological Impacts of Diabetes on the Susceptibility of Mycobacterium tuberculosis by Birhanu Ayelign, Markos Negash, Meaza Genetu, Tadelo Wondmagegn, Tewodros Shibabaw

“…The initiation of adaptive immunity is delayed by impaired antigen-presenting cell (APC) recruitment and function in hyperglycemic host, which results in reduced frequencies of Th1, Th2, and Th17 cells and its secretion of cytokines having a great role in activation of macrophage and inflammatory response of tuberculosis. …”
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Temporomandibular Disorders Related to Stress and HPA-Axis Regulation by Kordian Staniszewski, Henning Lygre, Ersilia Bifulco, Siv Kvinnsland, Lisa Willassen, Espen Helgeland, Trond Berge, Annika Rosén

“…Our findings indicate that patients with TMDs may have an upregulated HPA axis with higher F secretion from the adrenal cortex. Anxiety/depression and pain catastrophizing scores were significantly higher in the TMD group, and psychological factors may contribute to chronic upregulation of the HPA axis.…”
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Sirolimus Enhances Cyclosporine A-Induced Cytotoxicity in Human Renal Glomerular Mesangial Cells by Séin O'Connell, Craig Slattery, Michael P. Ryan, Tara McMorrow

“…CsA treatment increased profibrotic TGF-β1 secretion in human mesangial cells whereas SRL did not, indicating a role for TGF-β in CsA toxicity. …”
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Giant Prolactinoma of Young Onset: A Clue to Diagnosis of MEN-1 Syndrome by Chandrika Jayakanthi Subasinghe, Noel Somasundaram, Pathmanathan Sivatharshya, Lalana Devi Ranasinghe, Márta Korbonits

“…Giant prolactinoma is defined as tumours larger than 40mm with very high prolactin secretion. We report two unrelated Sri Lankan patients (8-year-old boy and a 20-year-old female) who presented with giant prolactinomas with mass effects of the tumours. …”
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Diagnosis and treatment of the functional dyspepsia: clinical guidelines of the Russian Gastroenterological Association by V. T. Ivashkin, I. V. Mayev, A. A. Sheptulin, T. L. Lapina, A. S. Trukhmanov, I. M. Kartavenko, V. A. Kiprianis, O. Z. Okhlobystina

“…Treatment is based on the stepwise approach, that includes general procedures, application of the drugs reducing hydrochloric acid secretion and normalizing motility and visceral sensitivity of the stomach and duodenum, in difficult to treat cases - psychopharmacological drugs and psychotherapeutic methods. …”
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Clinical features and diagnostic criteria of diseases of esophagogastroduodenal zone in patients with gallstone disease after cholecystectomy by I. V. Kozlova, Ye. V. Graushkina

“…After operation secretory and motor dysfunction of gastroduodenal zone aggravated: significantly more frequent decrease secretion of muriatic acid, duodenogastric and duodenogastroesophageal refluxes were found. …”
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Dendritic Cells from Aged Subjects Display Enhanced Inflammatory Responses to Chlamydophila pneumoniae by Sangeetha Prakash, Sudhanshu Agrawal, Dandan Ma, Sudhir Gupta, Ellena M. Peterson, Anshu Agrawal

“…In contrast, the secretion of IL-10 and innate interferons, IFN-α and IFN-λ, was severely impaired in DCs from aged donors. …”
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The Antiseptic Octenidine Inhibits Langerhans Cell Activation and Modulates Cytokine Expression upon Superficial Wounding with Tape Stripping by Nenad Nikolić, Philip Kienzl, Pooja Tajpara, Martin Vierhapper, Johannes Matiasek, Adelheid Elbe-Bürger

“…In the present study, we have used a superficial wound model using tape stripping on human full-thickness skin ex vivo to investigate the influence of OCT on epidermal Langerhans cells (LCs) and cytokine secretion pattern of skin cells during wound healing in a model without disruption of the normal skin structure. …”
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Extracellular Vesicles of Mesenchymal Stem Cells Are More Effectively Accessed through Polyethylene Glycol-Based Precipitation than by Ultracentrifugation by Lei Jia, Bo Li, Cong Fang, Xiaoyan Liang, Yingjun Xie, Xiaofang Sun, Wen Wang, Lei Zheng, Ding Wang

“…In our THP-1 model of LPS induction, MSC-EVs did not lead to a change in protein expression but inhibited the LPS-induced increase in cytokine secretion. UC-EVs were more effective for TNF-α inhibition, and PEG-EVs were more effective for IL10 inhibition. …”
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A Novel Rose Hip Preparation with Enhanced Anti-Inflammatory and Chondroprotective Effects by Joseph Schwager, Nathalie Richard, Rotraut Schoop, Swen Wolfram

“…RH-A and RH-B diminished the secretion of chemokines and cytokines in LPS/IFN-γ-activated PBL, including CCL5/RANTES, CXCL10/IP-10, interleukin- (IL-) 6, and IL-12. …”
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Characterization of Escherichia coli outer membrane vesicles and the impact of pathogenic ones on NLR signaling pathways by Roghayeh Mohammadzadeh, Ava Behrouzi, Farzam Vaziri, Seyed Davar Siadat

“… Background and Objectives: The secretion of outer membrane vesicles (OMVs) is a universal event among bacteria. …”
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Adolescents with Type I Diabetes Mellitus and their Knowledge about the Disease by Marisleidy Denis Rodríguez, Antonio Masot Rangel, Nicolás Ramón Cruz Pérez, Juan Carlos Yanes Macías, Mayumi Hernández Díaz

“…<strong>Background:</strong> diabetes mellitus is an endocrine-metabolic disease characterized by high levels of glucose in blood that occurs due to a deficient secretion or action of insulin. It is a growing health problem.…”
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Application of Metagenomic Next-Generation Sequencing in the Diagnosis of Infectious Keratitis by Xin-Yu Pan, Meng Wang, Yi-Dan Xu, Lin-Nong Wang

“…The positivity rates of secretion culture, corneal laser confocal microscopy (CM), mNGS, and pathological sections were 47.3% (133/281), 45.3% (111/245), 83.9% (104/124), and 19.3% (40/207), respectively. …”
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Sex-Biased Immune Responses to Antibiotics during Anti-PD-L1 Treatment in Mice with Colon Cancer by Nan Jing, Luoyang Wang, Huiren Zhuang, Chao Ai, Guoqiang Jiang, Zheng Liu

“…We observed that two narrow-spectrum antibiotics, neomycin and metronidazole, were more effective in alleviating colitis, as evidenced by the remission of loss of the body weight, enlargement of the spleen, shortening of the colon, secretion of proinflammatory cytokines, and histological score of the colon tissue. …”
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Negative Effects of SIGIRR on TRAF6 Ubiquitination in Acute Lung Injury In Vitro by Feng Tian, Qiang Lu, Jie Lei, Yunfeng Ni, Nianlin Xie, Daixing Zhong, Guang Yang, Shaokui Si, Tao Jiang

“…Such modulation between TRAF6 and SIGIRR could affect cytokine secretion and exacerbate the immune response; the IL-8, NFKB1, and NFKBIA mRNA levels were reduced after SIGIRR overexpression. …”
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TLR2 Expression in Relation to IL-6 and IL-1β and their Natural Regulators Production by PMN and PBMC in Patients with Lyme Disease by Ewa Jablonska, Magdalena Marcinczyk

“…An effect of rhIL-15 on TLR2 and cytokine secretion was also studied. Increased TLR2 expression in unstimulated neutrophils suggests an important role of these cells in mechanism recognition of B burgdorferi in patients with Lyme disease. …”
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Mature tertiary lymphoid structure associated CD103+ CD8+ Trm cells determined improved anti-tumor immune in breast cancer by Qin Fang, Shuru Chen, Xiaoyue Chen, Wei Zou, Di Chen, Yukang Huang, Chucheng Wu

“…Additionally, the proportions of CD103+ CD8+ Trm cells and NK cells were significantly increased with the gradual maturation of TLS. Furthermore, the secretion function of effector molecules by CD8+ CD103+ Trm cells and NK cells within TLSs was significantly enhanced, indicating a strong correlation between the effector function of CD103+ CD8+ Trm and NK cells and the maturity of TLSs.ConclusionOur study identifies potential additional prognostic information for the clinical prognosis of breast cancer patients, underscoring the prognostic significance of immune cells within TLS, with a particular focus on CD103+ CD8+ Trm cells and NK cells.…”
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The Angiogenic Potential of DPSCs and SCAPs in an In Vivo Model of Dental Pulp Regeneration by Petra Hilkens, Annelies Bronckaers, Jessica Ratajczak, Pascal Gervois, Esther Wolfs, Ivo Lambrichts

“…After twelve weeks, histological and ultrastructural analysis demonstrated the regeneration of vascularized pulp-like tissue as well as mineralized tissue formation in all stem cell constructs. Despite the secretion of vascular endothelial growth factor in vitro, the stem cell constructs did not display a higher vascularization rate in comparison to control conditions. …”
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