sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway by Yatao Bao, Meng Lian, Yong Chen, Xiaotian Gu, Kunyu Cao, Xiaoping Du, Jiyu Ju

“…The results showed that sNASP gene mutations can promote the response of the TLR4–TAK1 signaling pathway but have no significant effect on the TLR4–TBK1 signaling pathway. sNASP mutations enhanced TLR4-mediated nuclear factor-κ-gene binding and mitogen-activated protein kinase activation and IL-6, tumor necrosis factor secretion in murine peritoneal macrophages. Collectively, our study revealed the impact of sNASP gene mutation on the sensitivity of TLR4 receptors in mouse peritoneal macrophages and shed light on potential mechanisms underlying inflammation in autoimmune diseases.…”
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Caractérisation et délimitation de la catégorie des libfixes en anglais by Caroline Marty

“…I will show that libfixation is a morphological process that generates very productive schemas based on recutting and semantic secretion. From a diachronic perspective, the libfix is first used by speakers to coin new ad hoc expressions, and it then becomes entrenched as a full-fledged construction capable of yielding a series of types.…”
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Immunomodulatory effects of inosine pranobex on cytokine production by human lymphocytes by Lasek Witold, Janyst Michał, Wolny Rafał, Zapała Łukasz, Bocian Katarzyna, Drela Nadzieja

“…Inos enhanced TNF-a secretion significantly (in short-term - 24-hour, and prolonged term - 72-hour cultures) and IFN-g (in 72-hour cultures). …”
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P2X7 Receptor Function in Bone-Related Cancer by Elena Adinolfi, Francesca Amoroso, Anna Lisa Giuliani

“…Moreover, P2X7 receptor is involved in osteoclast differentiation, RANKL expression, matrix metalloproteases and cathepsin secretion thus promoting bone resorption and osteolytic lesions. …”
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Prediction of IL4 Inducing Peptides by Sandeep Kumar Dhanda, Sudheer Gupta, Pooja Vir, G. P. S. Raghava

“…The secretion of Interleukin-4 (IL4) is the characteristic of T-helper 2 responses. …”
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An Overview on Dry Eye Treatment: Approaches for Cyclosporin A Delivery by Burçin Yavuz, Sibel Bozdağ Pehlivan, Nurşen Ünlü

“…Artificial tear drops, tear retention treatment, stimulation of tear secretion, or anti-inflammatory drugs may be used for dry eye treatment according to the severity of the disease. …”
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Immunological Mechanisms in Allergic Diseases and Allergen Tolerance: The Role of Treg Cells by D. Calzada, S. Baos, L. Cremades-Jimeno, B. Cárdaba

“…By means of molecule secretion and cell-cell contact mechanisms, Tregs may have the capacity to modulate effector T cells and suppress the action of proinflammatory cytokines across a broad range of cell types. …”
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TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 Phosphorylation in Human Plasmacytoid Dendritic Cells by L. Kui, G. C. Chan, P. P. W. Lee

“…Given the rise of importance in identifying tumor necrosis stimulated gene 6 (TSG-6) as a key anti-inflammatory regulator, we investigate its function and its ability to counteract proinflammatory cytokine secretion by pDCs in vitro. CpG-A and R837 induced significant endogenous TSG-6 expression in the pDC cell-line GEN2.2. …”
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Toxicological Implications of Platinum Nanoparticle Exposure: Stimulation of Intracellular Stress, Inflammatory Response, and Akt Signaling In Vitro by Claudia J. Labrador-Rached, Rebecca T. Browning, Laura K. Braydich-Stolle, Kristen K. Comfort

“…However, lower, subtoxic PtNP concentrations were able to elicit multiple stress responses, secretion of proinflammatory cytokines, and modulation of insulin-like growth factor-1 dependent signal transduction. …”
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Resistance of Some Rice Varieties (Oryzae sativa Linnaeus) to the Brown Planthopper (Nilaparvata lugens Stal) using the Honey Dew Test by Widya Puspita Sari, James Rinaldi, Dedi Darmadi, Arneti Arneti

“…Keywords: Honeydew, resistant, secretion, susceptable,  sticky rice …”
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Composition and functional diversity of soil and water microbial communities in the rice-crab symbiosis system. by Guo Yang, Tian Juncang, Wang Zhi

“…The dominant phylum may rely on mechanisms such as organic matter catabolism, secretion of secondary metabolites and phototrophic autotrophy, as predicted by functional gene analysis. …”
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A Two-Pathway Mathematical Model of the LH Response to GnRH that Predicts Self-Priming by J. J. Evans, T. M. Wilkinson, D. J. N. Wall

“…Thus, we have provided an explanation for details of the nature of the profile of LH secretion and additionally enabled incorporation of cAMP in an integrating model. …”
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Osmotic myelinolysis: literature review and case report by G. Rutkauskaitė, A. Klimašauskienė

“…Hyponatremia is commonly found in patients with chronic alcoholism and malnutrition and can be caused by liver diseases, the syndrome of inappropriate antidiuretic hormone secretion, as well as adrenal insufficiency and iatrogenic disorders. …”
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Effect of Monotherapy and Combination Therapy of Pantoprazole and Aprepitant in Gastric Esophageal Reflux Disease in Albino Rats by Kamleshwar Shukla, Prince Raj, Arun Kumar, Mukesh Kumar, Gaurav Kaithwas

“…Treatment with pantoprazole and aprepitant significantly inhibited the gastric secretion, total acidity, and esophagitis index. The treatment also helped to restore the altered levels oxidative stress parameters to normal.…”
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Glucose Management during Insulinoma Resection Using Real-Time Subcutaneous Continuous Glucose Monitoring by Yuki Sugiyama, Chiaki Kiuchi, Maiko Suzuki, Yuki Maruyama, Ryo Wakabayashi, Yasunari Ohno, Shugo Takahata, Takumi Shibazaki, Mikito Kawamata

“…Insulinoma is a rare neuroendocrine tumor that causes hypoglycemia due to unregulated insulin secretion. Blood glucose management during insulinoma resection is therefore challenging. …”
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Overview of Platelet Physiology: Its Hemostatic and Nonhemostatic Role in Disease Pathogenesis by Kakali Ghoshal, Maitree Bhattacharyya

“…Dynamic platelets bear distinct morphology, where α and dense granule are actively involved in secretion of molecules like GPIIb , IIIa, fibrinogen, vWf, catecholamines, serotonin, calcium, ATP, ADP, and so forth, which are involved in aggregation. …”
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Immunity in the Cervix: Interphase between Immune and Cervical Epithelial Cells by Jorgelina Barrios De Tomasi, Michael Makokha Opata, Chishimba Nathan Mowa

“…These (ways) include mounting physical (intercellular junctions, secretion of mucus) and immune barriers (pathogen-recognition receptor-mediated pathways), which collectively and ultimately lead to the release of specific chemokines and or cytokines. …”
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Stress-Induced Changes in the Gastrointestinal Motor System by Victor Plourde

“…In animals, the most consistent findings include retardation of gastric emptying in response to various stressors; acceleration of gastric emptying upon cold stress, presumably through the secretion of brain thyroglobulin-hormone; acceleration of intestinal transit; and stimulation of colonic transit and fecal output. …”
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Functional Development of the Human Gastrointestinal Tract: Hormone- and Growth Factor-Mediated Regulatory Mechanisms by Daniel Ménard

“…In the third section, emphasis is placed on the functional development of human fetal stomach and its various epithelial cell types; in particular, the glandular chief cells responsible for the synthesis and secretion of gastric enzymes such as pepsinogen-5 and gastric lipase. …”
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