Study of long-acting vs daily growth hormone: peak levels, AUC, action duration, and IGF-1 by Ashraf Soliman, Fawzia Alyafei, Nada Alaaraj, Noor Hamed, Shayma Mohamed, Ahmed Elawwa, Vincenzo De Sanctis

“…Objectives: This review assesses the impact of LAGH therapy on serum levels of GH and insulin-like growth factor-1 (IGF-1) and evaluates the potential metabolic and safety risks compared to the natural pulsatile secretion of GH and daily GH injections in normal children. …”
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Flavones enrich rhizosphere Pseudomonas to enhance nitrogen utilization and secondary root growth in Populus by Jiadong Wu, Sijia Liu, Haoyu Zhang, Sisi Chen, Jingna Si, Lin Liu, Yue Wang, Shuxian Tan, Yuxin Du, Zhelun Jin, Jianbo Xie, Deqiang Zhang

“…Moreover, we confirm that Pseudomonas is strongly associated with tricin and apigenin biosynthesis and identify that gene GLABRA3 (GL3) is critical for tricin secretion. The elevated tricin secretion via constitutive transcription of PopGL3 and Chalcone synthase (PopCHS4) can drive Pseudomonas colonization in the rhizosphere and further enhance poplar growth, nitrogen acquisition, and secondary root development in nitrogen-poor soil. …”
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VEGF in the Crosstalk between Human Adipocytes and Smooth Muscle Cells: Depot-Specific Release from Visceral and Perivascular Adipose Tissue by Raphaela Schlich, Miriam Willems, Sabrina Greulich, Florian Ruppe, Wolfram Trudo Knoefel, D. Margriet Ouwens, Bujar Maxhera, Artur Lichtenberg, Jürgen Eckel, Henrike Sell

“…CM increases VEGF-receptor (VEGF-R) 1 and 2 expression and VEGF secretion of VSMC, while OA only stimulates VEGF secretion. …”
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2′-O-Methylperlatolic Acid Enhances Insulin-Regulated Blood Glucose-Lowering Effect through Insulin Receptor Signaling Pathway by Wang Yinghao, Guan Qiaoli, Liu Guanfu, Wu Xiaoyun, Wang Xuanjun, Sheng Jun

“…Further, 2-O-M significantly increased glucagon secretion and enhanced liver gluconeogenesis to prevent hypoglycemia. …”
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The effect of continuous positive airway pressure (CPAP) application on airway problems in pediatric patients with subglottic stenosis who undergo balloon dilatation by Zeliha Tuncel, Şenay Göksu, Özlem Deligöz, Kemal Tolga Saracoglu, Abdulatif Albasha, Bushra M. Abdallah, Ayten Saracoglu

“…Compared to controls, the proportions of bronchospasm, tracheal secretion, need for intensive care, and tracheostomy were consistently lower in the CPAP group, whereas the requirement of intubation was higher. …”
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ADAM-10 Regulates MMP-12 during Lipopolysaccharide-Induced Inflammatory Response in Macrophages by Yan Jiang, Qiming Gong, Jinmei Huang, Yuanxun Gong, Qiang Tang, Dalong Wei, Qianli Tang, Jingjie Zhao, Jian Song, Lingzhang Meng

“…Cell viability was increased in EX ADAM-10 cells, and ADAM-10 secretion was further increased in the EX and LPS groups. …”
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Purine-Metabolizing Ectoenzymes Control IL-8 Production in Human Colon HT-29 Cells by Fariborz Bahrami, Filip Kukulski, Joanna Lecka, Alain Tremblay, Julie Pelletier, Liliana Rockenbach, Jean Sévigny

“…We previously observed that IL-8 secretion and function can be modulated by nucleotide (P2) receptors. …”
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Importance of Self-Care in Elderly Adults with Diabetes Mellitus by Ydalsys Naranjo Hernández, José Alejandro Concepción Pacheco

“…Diabetes mellitus is a syndrome characterized by hyperglycemia which is caused by an absolute or relative deterioration of insulin secretion. It is a complex process of metabolism of carbohydrates, fats and proteins. …”
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Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus by Bikash Adhikari

“…., alkaloids, show antidiabetic activity through the inhibition of enzymes (α-amylase, α-glucosidase, aldose reductase, dipeptidyl peptidase-IV, and protein tyrosine phosphatase-1B); inhibition of advanced glycation end products; increment of insulin secretion and its sensitivity; enhancement of glucose uptake; and their antioxidant ability. …”
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Short Bowel Syndrome: Intestinal Adaptation and Medical Therapy by WD Buie, OG Thurston, Richard N Fedorak

“…The mechanisms of intestinal adaptation are not entirely understood; however, they can be grouped into three broad categories: luminal nutrition, hormonal factors, and pancreaticobiliary secretion. Medical treatment of short bowel syndrome remains supportive and centres around the control of three pathophysiological defects: decreased intestinal transit time, gastric hypersecretion, and reduced functional mucosal surface area.…”
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Progranulin Inhibits Human T Lymphocyte Proliferation by Inducing the Formation of Regulatory T Lymphocytes by Kyu Hwan Kwack, Hyeon-Woo Lee

“…PGRN-mediated inhibition of T lymphocyte proliferation, as well as the induction of iTregs, was completely reversed by a TGF-β inhibitor or a Treg inhibitor. PGRN induced TGF-β secretion in the presence of PHA whereas it did not in the absence of PHA. …”
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Clinical Practice Guidelines for Severe Asthma Treatment. by Eddy Pereira Valdes, Moisés Santos Peña, Belkys Rodríguez Llerena

“…This disease is characterized by an overreaction of the tracheobronchial tree with hyperactivity after certain stimulus consisting of a diffuse narrowing of the respiratory ways related with an excessive contraction of the bronchial smooth muscle, hyper-secretion of mucus and mucosa edema. It is spontaneously reversible or reversible after treatment. …”
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Evaluation of Haematological and Immunological Status in Type 2 Diabetics by A. Sohna Chandra Packiavathy, M. Ramalingam

“…Type 2 diabetes is a heterogeneous disorder involving impairment of both insulin secretion and insulin action. The immunological and haematological statuses during normal and diseased conditions have been studied. …”
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Mechanisms Linking Vitamin D Deficiency to Impaired Metabolism: An Overview by Nurulmuna Mohd Ghozali, Nelli Giribabu, Naguib Salleh

“…Current evidence indicates that the deficiency of vitamin D could impair the pancreatic β-cell functions, thus compromising its insulin secretion. Besides, vitamin D deficiency could also exacerbate inflammation, oxidative stress, and apoptosis in the pancreas and many organs, which leads to insulin resistance. …”
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Liposarcoma in the thoracic wall. Case study. by Julio Sarmiento Sánchez, Lidia Torres Aja, Dorys González Díaz

“…The physical examination showed a big ulcerated tumor of about 20 cm of diameter with yellow secretion. It turned to be a lymphosarcoma grade II, with wide necroses zones, diameter of 20x14x7 cm and weighing 746grs. …”
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Small Bowel Review: Part II by ABR Thomson, JA Thomson, MJ Ropeleski, GE Wild

“…Topics discussed are enterocyte proliferation and growth factors; amino acids, peptides and allergies; motility; salt and water absorption and secretion – diarrhea; vitamins and minerals; early development and ageing of the intestine; and ethanol effects.…”
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Leptin levels in obese women with and without type 2 diabetes mellitus by Mehmet Akif Buyukbese, Ali Cetinkaya, Ramazan Kocabas, Aytekin Guven, Mehmet Tarakcioglu

“…INTRODUCTION: The role of leptin has been more clear in the endocrinology area after the discovery of its secretion from the adipose tissue. The aim of the study is to investigate the leptin levels in obese women in whom type 2 diabetes mellitus were present or absent.…”
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Single monoclonal spike characterized as double monoclonal gammopathy in a patient with multiple myeloma: A rare finding by Rajni Saijpaul, Vatsala Khurana, Rashmi Verma, Smita Kaushik

“…Multiple myeloma (MM) is associated with the secretion of a unique monoclonal protein (M-protein) due to overproduction of immunoglobulin (Ig) by a clone of abnormally proliferating plasma cells. …”
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Upregulating Nonneuronal Cholinergic Activity Decreases TNF Release from Lipopolysaccharide-Stimulated RAW264.7 Cells by Yi Lv, Sen Hu, Jiangyang Lu, Ning Dong, Qian Liu, Minghua Du, Huiping Zhang

“…Upregulating choline acetyltransferase (ChAT) expression through ChAT gene transfection could enhance ACh secretion and reduce TNF release from the infected RAW264. 7cells. …”
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Diagnostics and treatment of pancreatic exocrine insufficiency: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, A. V. Okhlobystin, S. A. Alekseyenko, Ye. V. Beloborodova, Yu. A. Kucheryavy, T. L. Lapina, A. S. Trukhmanov, I. B. Khlynov, M. V. Chikunova, A. A. Sheptulin, O. S. Shifrin

“…PEI in the state it which secretion of pancreatic enzymes into duodenum is insufficient for normal digestion of nutrients. …”
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