Thiazolidinediones and Fertility in Polycystic Ovary Syndrome (PCOS) by Pascal Froment, Philippe Touraine

“…We report in this review different hypotheses of thiazolidinediones actions to improve PCOS (steroid secretion by ovarian cells ; insulin sensitivity in muscle and adipocyte and fat redistribution).…”
Get full text

Tuttle mealybug Brevennia rehi (Pseudococcidae) by Ian Stocks

“…Because Bermuda and zoysia are important lawn grasses, especially in the southern United States, infestation by Tuttle mealybug should be considered whenever dieback is noticed, especially if the grass blades show white wax or are sticky from honeydew secretion. Both Bermuda and zoysia lawns are commonly installed as sod or plugs, which provide a ready route for the spread of infestations should the pest control practices of the grower fail to maintain a pest-free production environment. …”
Get full text

Absence of Effect of Somatostatin Analogue (SMS 201-995) in Diarrhea Associated with Inflammatory Bowel Disease by Richard N. Fedorak, Richard W. Sherbaniuk

“…The octapeptide long acting somatostatin analogue, SMS 201-995 promotes intestinal fluid and electrolyte absorption and inhibits anion secretion. It is more potent than native somatostatin and does not exhibit tachyphylaxsis. …”
Get full text

Tuttle mealybug Brevennia rehi (Pseudococcidae) by Ian Stocks

“…Because Bermuda and zoysia are important lawn grasses, especially in the southern United States, infestation by Tuttle mealybug should be considered whenever dieback is noticed, especially if the grass blades show white wax or are sticky from honeydew secretion. Both Bermuda and zoysia lawns are commonly installed as sod or plugs, which provide a ready route for the spread of infestations should the pest control practices of the grower fail to maintain a pest-free production environment. …”
Get full text

Development and in vitro evaluation of biomimetic injectable hydrogels from decellularized human nerves for central nervous system regeneration by Gopal Agarwal, Kennedy Moes, Christine E. Schmidt

“…Compared to LPS-activated cells on tissue culture plates (TCP), astrocytes within iHPN maintained a quiescent state, as evidenced by reduced GFAP expression and IL-1β secretion. RAW 264.7 and HMC3 cells in iHPN displayed an anti-inflammatory phenotype, as shown by increased CD206 and decreased CD86/CD68 expression, along with higher IL-4 and lower TNF-α/IL-1β secretion. …”
Get full text

Diverse biological roles of PhoP/PhoQ in Pseudomonas plecoglossicida: Impact on stress responses and virulence by Meiqin Mao, Li He, Xiangyang Lin, Jianshao Wu, Pan Wang, Chuanzhong Zhu, Qingpi Yan

“…Among these, genes related to flagellar assembly, two-component systems, type III secretion systems, and bacterial chemotaxis were downregulated, while genes involved in ABC transport, magnesium ion transport, type VI secretion systems, and membrane permeability were upregulated. …”
Get full text

Fitness costs of Mycobacterium tuberculosis resistant to rifampicin is compensated by rapid Th2 polarization mediated by early and high IL-4 production during mice infection by Ma. Fernanda Arce-Aceves, Roberto Espinosa-Neira, Dulce A. Mata-Espinosa, Jorge A. Barrios-Payan, Hugo G. Castelán-Sánchez, Sofía L. Alcaraz-Estrada, Mauricio Castañón-Arreola, Rogelio Hernández-Pando

“…Thus, high and rapid bias to Th2 response is a mechanism of Mtb virulence, which could be mediated by rifampicin-resistant Mtb isolates, probably by high production and secretion of specific antigens.…”
Get full text

B cells enhance IL-1 beta driven invasiveness in triple negative breast cancer by Nicole J. Toney, Lynn M. Opdenaker, Lisa Frerichs, Shirin R. Modarai, Aihui Ma, Holly Archinal, Grace O. Ajayi, Jennifer Sims-Mourtada

“…These findings suggest that early B cell presence in TNBC can induce IL-1β secretion, enhancing invasion and mobility through IL-1β-NFκB signaling. …”
Get full text

Insulin resistance and β-cell dysfunction in individuals with normal glucose tolerance but elevated 1-h post-load plasma glucose by Qianwen Nie, Xue Jin, Yahui Mu, Youyuan Huang, Aimei Dong

“…Glucose and insulin curves showed that the NGT group with 1-h PG ≥ 8.6 mmol/L exhibited glucose profiles similar to those with isolated impaired fasting glucose (I-IFG), marked by elevated glucose, early insulin secretion impairment, and delayed insulin peaks. Older individuals (≥ 65 years) had higher glucose and a higher prevalence of abnormal 1-h PG but showed no significant differences in IR or β-cell dysfunction compared to younger individuals.ConclusionsA 1-h PG ≥ 8.6 mmol/L in individuals with NGT is associated with substantial β-cell dysfunction, highlight the value of incorporating 1-h PG measurement into diagnostic assessments for early detection of insulin secretion impairments across age groups.…”
Get full text

Incidence and Associated Factors of Laryngospasm among Pediatric Patients Who Underwent Surgery under General Anesthesia, in University of Gondar Compressive Specialized Hospital,... by Wubie Birlie Chekol, Debas Yaregal Melesse

“…Prompt clearing of airway secretions and adequate depth of anesthesia may help to prevent laryngospasm. …”
Get full text

Interferon-γ production in response to the cytotoxic T lymphocyte epitope within an antigen incorporated in simian virus 40 virus-like particles by Takeharu Watanabe, Masayuki Hayashi, Masaaki Arai, Sho Matsushita, Hiroshi Handa, Masaaki Kawano

“…Administration of SV40 VLPs upregulated expression of CD63/CD68/CD83/CD86/CD196, and induced secretion of C-C chemokine ligand (CCL)3 and CCL4, by B cells, as well as secretion of CCL4 by T cells and tumor necrosis factor-α by bone marrow-derived dendritic cells.…”
Get full text

Reduction of Hepatic Fat Content by Dulaglutide for the Treatment of Diabetes Mellitus: A Two‐Centre Open, Single‐Arm Trial by Chuanfeng Liu, Yu Xin, Yajing Huang, Lili Xu, Ruizhi Zhou, Yangang Wang, Wei Wang

“…Conclusion Reduction in liver fat content effectively improves pancreatic islet function secretion, particularly postprandial c‐peptide secretion, especially in the first hour after a meal. …”
Get full text

Effect of Alkali Lignin on Laccase Activity and Mycelial Biomass of Flammulina velutipes by Mei-Ling Han, Yi-Lin Zhao, Tian-Yu Liu, Lu-Sen Bian, Zi-Han Li, Ming-Xue Li, Jia Li, Xiao-Qi Yang, Qi An

“…The effect of alkali lignin on laccase activity and mycelial biomass of Flammulina velutipes was investigated under different fermentation temperature. The secretion of laccase by F. velutipes has certain specificity. …”
Get full text

Effect of afzelin on inflammation and lipogenesis in particulate matter-stimulated C. acnes-treated SZ95 sebocytes by Ji Yeon Hong, Yong Hee Choi, Yoon Jin Roh, Mi-Kyung Lee, Christos C. Zouboulis, Kui Young Park

“…Interestingly, the upregulated inflammatory and lipogenic gene expression induced by C. acnes and PM was attenuated by afzelin treatment.ConclusionsThis study's findings indicate that PM potentially aggravates acne by acting on both inflammation and sebum secretion. They also reveal afzelin's ability to suppress these phenomena by not only suppressing inflammatory cytokine expression but also inhibiting sebogenesis. …”
Get full text

Was It an Adrenocortical Adenoma or an Adrenocortical Carcinoma? Limitation of the Weiss Scoring System in Determining the Malignant Potential of Adrenocortical Tumor: Report on Tw... by Cheuk-Lik Wong, Chun-Kit Fok, Yuk-Kit Chan, Vicki Ho-Kee Tam, Lai-Ming Fung

“…Twenty-four-hour urine steroid profiling revealed co-secretion of adrenal androgens and atypical steroid metabolites. …”
Get full text

Quality profile of milk from high producing dairy cows vaccinated against mastitis by M. N. Isakova, U. V. Sivkova, M. V. Ryaposova, I. A. Shkuratova, A. V. Lysov

“…Tests of mammary gland secretions revealed Streptococcus spp. in 27.27% of cases, Staphylococcus aureus and Entеrococcus faecium were isolated in 18.18% of tested samples. …”
Get full text

Manufacturing Strategy for Multiwalled Carbon Nanotubes as a Biocompatible and Innovative Material by Hisao Haniu, Naoto Saito, Yoshikazu Matsuda, Yuki Usui, Kaoru Aoki, Masayuki Shimizu, Nobuhide Ogihara, Kazuo Hara, Seiji Takanashi, Masanori Okamoto, Koichi Nakamura, Norio Ishigaki, Tamotsu Tsukahara, Hiroyuki Kato

“…However, cell viability was affected by MWCNT graphitization temperature and diameter. Moreover, cytokine secretion was apparently affected by treatment temperature, but not MWCNT diameter. …”
Get full text

Targeting OAS3 for reversing M2d infiltration and restoring anti-tumor immunity in pancreatic cancer by Shaopeng Zhang, Ximo Xu, Kundong Zhang, Changzheng Lei, Yitian Xu, Pengshan Zhang, Yuan Zhang, Haitao Gu, Chen Huang, Zhengjun Qiu

“…Our study revealed that PC cells (PCs) promote macrophage polarization toward M2d through high lactate secretion. M2d is characterized by elevated secretion of IL-10 and VEGF-A, which diminish CD8+T cells cytotoxicity and promote tumor neoangiogenesis simultaneously. …”
Get full text

AcfA Regulates the Virulence and Cell Envelope Stress Response of <i>Vibrio parahaemolyticus</i> by Huan Liu, Huayu Lei, Juanjuan Cao, Zhaobang Xie, Yile Shi, Yanni Zhao

“…The expression of genes associated with the type III secretion system, type VI secretion system, and oligopeptide permeases system were significantly reduced, and yet the expression of genes associated with cell envelope biosynthesis and response regulation system were enhanced dramatically in the absence of the <i>acfA</i> gene compared to the wild-type strain. …”
Get full text

Slight Pro-Inflammatory Immunomodulation Properties of Dendritic Cells by Gardnerella vaginalis: The “Invisible Man” of Bacterial Vaginosis? by Thomas Bertran, Patrick Brachet, Marjolaine Vareille-Delarbre, Julie Falenta, Annie Dosgilbert, Marie-Paule Vasson, Christiane Forestier, Arlette Tridon, Bertrand Evrard

“…The same profile was observed on lymphocytes with significant increases of proliferation and cytokine secretion only at the highest bacterial concentration. …”
Get full text