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481
A Case of Von Hippel–Lindau Disease with Bilateral Pheochromocytoma and Ectopic Hypersecretion of Intact Parathyroid Hormone in an Adolescent Girl
Published 2020-01-01“…In our case, the elevation of intact PTH and its spontaneous normalization after surgical treatment of pheochromocytomas confirms its ectopic secretion.…”
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482
Haptoglobin Genotype-Dependent Anti-Inflammatory Signaling in CD163+ Macrophages
Published 2013-01-01“…In this study, we examined whether scavenging of polymorphic Hp:Hb complexes differentially generated downstream anti-inflammatory signals in cultured human macrophages culminating in interleukin (IL)-10 secretion. We describe an anti-inflammatory signalling pathway involving phosphatidylinositol-3-kinase activation upstream of Akt phosphorylation (pSer473Akt) and IL-10 secretion. …”
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483
Sacrificing Alginate in Decellularized Extracellular Matrix Scaffolds for Implantable Artificial Livers
Published 2025-01-01“…The hepatocyte and endothelial cell scaffold treated with alginate lyase demonstrated the highest diffusion rate, along with enhanced albumin secretion (2.8 µg/mL) and urea synthesis (220 µg/mL) during the same period by day 10. …”
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484
Constipation at endocrine diseases
Published 2013-05-01“…Gastro-intestinal motility disorder at this syndrome is related to development of diabetic autonomous neuropathy, asynchrony of peristalsis and pressure of sphincters, acute decrease of cells of Cajal density, change of gastrointestinal hormones secretion. Constipation is typical symptom of hypothyroidism. …”
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485
The Correlation between Hormonal Disturbance in PCOS Women and Serum Level of Kisspeptin
Published 2020-01-01“…Kisspeptin is a neuropeptide that upregulates gonadotropin-releasing hormone (GnRH) secretion. It is an essential element for the luteinizing hormone (LH) surge and ovulation. …”
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486
Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway
Published 2022-01-01“…In vitro, the effects of PQQ on the secretion of epithelial-derived cytokines by house dust mite- (HDM-) incubated 16-HBE cells and on the differentiation potential of CD4+ T cells were investigated. …”
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487
What Do Gases in the Large Intestine Have to Do with Health?
Published 2025-02-01“…The gut-brain axis, regulated by the nervous system and gut microbiota, influences intestinal motility, hormone secretion, and metabolic processes. Gut microorganisms produce short-chain fatty acids (SCFAs), which play a significant role in regulating energy homeostasis and enteroendocrine hormone secretion. …”
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488
Critical appraisal of diagnostic laboratory tests in the evaluation of central precocious puberty
Published 2025-01-01“…Pubertal onset is characterized by reactivation of the hypothalamic-pituitary-gonadal axis resulting in pulsatile gonadotropin secretion and subsequent sex steroid production. Accurate measurements of the gonadotropins and sex steroids are essential to ensure timely diagnosis of precocious puberty, so as to determine optimal management. …”
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489
Immunoregulatory programs in anti‐N‐methyl‐D‐aspartate receptor encephalitis identified by single‐cell multi‐omics analysis
Published 2025-01-01“…TLR2 pathway activation in myeloid cells contributes to TNF‐α secretion and could influence adaptive immune responses.…”
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490
Production and metabolic responses of Montbéliarde and Holstein cows during the periparturient period and a sequential feed-restriction challenge
Published 2025-02-01“…Cows in third-and-greater lactation secreted more ECM, and had delayed resumption of luteal activity compared with second-lactation cows. …”
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491
Splenic Stromal Cells from Aged Mice Produce Higher Levels of IL-6 Compared to Young Mice
Published 2014-01-01“…Inflamm-aging indicates the chronic inflammatory state resulting from increased secretion of proinflammatory cytokines and mediators such as IL-6 in the elderly. …”
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492
Adipose-Derived Stem Cells in Bone Tissue Engineering: Useful Tools with New Applications
Published 2019-01-01“…In particular, we are going to analyze the different ASCs’ subpopulations, the interaction between ASCs and scaffolds, and the bioactive factors which are secreted by ASCs or can induce their osteogenic commitment. …”
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493
Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Grow...
Published 2016-01-01“…S1P exposure also triggered MMP-2 secretion from human MC. These studies identify a novel proangiogenic axis encompassing MC/S1P/S1PR2 likely relevant to inflammation.…”
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494
Cytokine Profile of Patients with Allergic Rhinitis Caused by Pollen, Mite, and Microbial Allergen Sensitization
Published 2017-01-01“…There was a higher production profile of TNF-α and TSLP in nasal secretion in the patients with perennial allergic rhinitis and additional high sensitization to SEs. …”
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495
Autoimmune and Neoplastic Thyroid Diseases Associated with Hepatitis C Chronic Infection
Published 2014-01-01“…HCV thyroid infection could act by upregulating CXCL10 gene expression and secretion in thyrocytes recruiting Th1 lymphocytes that secrete interferon-γ and tumor necrosis factor-α. …”
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496
Pyridoxal-5′-Phosphate Promotes Immunomodulatory Function of Adipose-Derived Mesenchymal Stem Cells through Indoleamine 2,3-Dioxygenase-1 and TLR4/NF-κB Pathway
Published 2019-01-01“…Initially, A-MSCs were obtained, and cytokine secretion and the expression of IDO1, NF-κB, and Toll-like receptors in PLP-stimulated A-MSCs were evaluated. …”
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497
Gastrospheres as a Model of Gastric Cancer Stem Cells Skew Th17/Treg Balance toward Antitumor Th17 Cells
Published 2020-01-01“…Finally, the cytotoxic potential of induced immune cells was measured by examining the secretion of lactate dehydrogenase from target cells. …”
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498
Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats
Published 2015-01-01“…Somatostatin analog octreotide completely blocked insulin secretion, impaired proliferation at low autocrine insulin, and decreased PPY secretion and mitochondrial DNA in INS-1E cells. …”
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499
Exenatide Is an Effective Antihyperglycaemic Agent in a Mouse Model of Wolfram Syndrome 1
Published 2016-01-01“…In contrast to other groups, wolframin-deficient mice had a lower insulin-to-glucose ratio during the intraperitoneal glucose tolerance test, indicating impaired insulin secretion. Exenatide increased the insulin-to-glucose ratio irrespective of genotype, demonstrating the ability to correct the impaired insulin secretion caused by wolframin deficiency. …”
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500
Serum Concentrations of Betatrophin and Its Association with Indirect Indices of Insulin Resistance and Beta Cell Function in Women with Polycystic Ovary Syndrome
Published 2017-01-01“…The aim of our study was to investigate the relationship of serum betatrophin concentrations with indirect indices of IR and insulin secretion in women with PCOS, compared to the control group. …”
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