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381
Effects of Simvastatin on Glucose Metabolism in Mouse MIN6 Cells
Published 2014-01-01“…The aim of this study was to investigate the effects of simvastatin on insulin secretion in mouse MIN6 cells and the possible mechanism. …”
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382
Protection Effect of Endomorphins on Advanced Glycation End Products Induced Injury in Endothelial Cells
Published 2013-01-01“…The results showed that the mRNA expression and secretion of eNOS were significantly enhanced after incubation with EMs compared to those with AGEs-BSA, while the secretion of NO and iNOS, mRNA expression, and secretion of ET-1 had opposite changes. …”
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383
Live imaging of paracrine signaling: Advances in visualization and tracking techniques
Published 2025-01-01“…This review examines recent advances in visualizing and tracking paracrine factors through four key stages: secretion from producing cells, diffusion through extracellular space, binding to target cells, and activation of intracellular signaling within target cells. …”
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384
KCNJ11: Genetic Polymorphisms and Risk of Diabetes Mellitus
Published 2015-01-01“…It is caused by defects in insulin secretion or insulin action or both, leading to hyperglycemia. …”
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385
Crotoxin Isolated from Crotalus durissus terrificus Venom Modulates the Functional Activity of Dendritic Cells via Formyl Peptide Receptors
Published 2018-01-01“…Differently, CTX and CB induced IL-10, PGE2 and LXA4 secretion in LPS-incubated DCs. Lower proliferation and IL-2 secretion were verified in coculture of CD3+ cells and DCs incubated with LPS plus CTX or CB compared with LPS-incubated DCs. …”
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386
Lipopolysaccharide alters CEBPβ signaling and reduces estradiol production in bovine granulosa cells
Published 2022-10-01“…Results Treatment with LPS increased CXCL8 and IL6 gene expression and reduced estradiol secretion in granulosa cells from both small/medium and large follicles. …”
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387
B Cells in Autoimmune Diseases
Published 2012-01-01“…The role of B cells in autoimmune diseases involves different cellular functions, including the well-established secretion of autoantibodies, autoantigen presentation and ensuing reciprocal interactions with T cells, secretion of inflammatory cytokines, and the generation of ectopic germinal centers. …”
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388
Forensic Body Fluid Identification by Analysis of Multiple RNA Markers Using NanoString Technology
Published 2013-12-01“…However, for saliva and vaginal secretion, no single marker was perfect. Thus, we designed a logistic regression model with multiple markers for saliva and vaginal secretion and achieved almost perfect identification. …”
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389
Antisecretory Action of the Extract of the Aerial Parts of Eremomastax speciosa (Acanthaceae) Occurs through Antihistaminic and Anticholinergic Pathways
Published 2014-01-01“…The extract significantly reduced (P<0.001) the volume of gastric secretion and significantly increased mucus production. …”
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390
Decreased Interleukin-4 Release from the Neurons of the Locus Coeruleus in Response to Immobilization Stress
Published 2016-01-01“…Acute IMO (2 h/day, once) stimulated secretion of plasma corticosterone and tyrosine hydroxylase (TH) in the LC whereas these increments were diminished in exposure to chronic stress (2 h/day, 21 consecutive days). …”
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391
lncRNA DLEU1 Modulates Proliferation, Inflammation, and Extracellular Matrix Degradation of Chondrocytes through Regulating miR-671-5p
Published 2022-01-01“…Elevated expression of miR-671-5p suppresses chondrocyte proliferation, degradation of ECM, and secretion of inflammation mediators. DLEU1 overexpression promotes chondrocytes proliferation, degradation of ECM, and secretion of inflammation mediators via regulating miR-671-5p. …”
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392
Reduced Expression of VAMP8 in Lacrimal Gland Affected by Chronic Graft-versus-Host Disease
Published 2017-01-01“…Next, serial changes of tear secretion and VAMP8 expression at both protein and mRNA level of LG in an animal cGVHD model compared with the syngeneic control. …”
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393
The role of KNDy neurons in human reproductive health
Published 2024-08-01“…Kiss1 neurons in humans are concentrated in the infundibular nucleus (equivalent to the ARC), with few Kiss1 neurons localized to the preoptic area (equivalent to the AVPV), and the mechanisms underlying GnRH surge secretion in humans are poorly understood. However, peripheral administration of kisspeptin to humans promotes gonadotropin secretion, and administration of kisspeptin to patients with hypothalamic amenorrhea or congenital hypogonadotropic hypogonadism restores the pulsatile secretion of GnRH/luteinizing hormone. …”
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394
The Art of Managing Various Ocular Defects in Different Clinical Scenarios: A Case Series
Published 2023-07-01“…This case series describes methods of fabricating ocular prosthesis indicated in different scenarios: the modified stock ocular and a custom-made ocular prosthesis when tearing secretion is enough in the eye socket and an ocular prosthesis with a tear reservoir in cases showing reduced tear secretion. …”
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395
Recent Advances in Potential Clinical Application of Ghrelin in Obesity
Published 2012-01-01“…Ghrelin stimulates growth hormone secretion, but also appetite, food intake, weight gain, and gastric emptying. …”
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396
The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach
Published 2019-01-01“…According to targeted proteomic analysis, 3-month-old HHTg rats (in comparison to age-matched controls) exhibited increased urinary secretion of proinflammatory parameters (MCP-1, IL-6, IL-8, P<0.01) and decreased urinary secretion of epidermal growth factor (EGF, P<0.01) before manifestation of microalbuminuria. …”
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397
Plasma prolactin axis shift from placental to pituitary origin in late prepartum mice
Published 2024-07-01“…A report from 1984 examined the secretion pattern of PRL3B1 in prepartum mice. In the current study, we found contradictory findings in the secretion pattern that invalidate the previous report. …”
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398
CD22 modulation alleviates amyloid β-induced neuroinflammation
Published 2025-02-01“…Further, membrane CD22 inhibited Amyloid β (Aβ) induced-NFκB signaling pathway and mechanistic study delineated that suciraslimab suppressed Aβ-induced IL-1β secretion in human microglia and PBMC. Suciraslimab also suppressed IL-12 and IL-23 secretion in human PBMC. …”
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399
Adipose Tissue-Derived Mesenchymal Stem Cells Exert In Vitro Immunomodulatory and Beta Cell Protective Functions in Streptozotocin-Induced Diabetic Mice Model
Published 2015-01-01“…Proliferation, cytokine production, and insulin secretion assays were performed in coculture experiments. …”
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400
Inhibition of Epithelial CC-Family Chemokine Synthesis by the Synthetic Chalcone DMPF-1 via Disruption of NF-κB Nuclear Translocation and Suppression of Experimental Asthma in Mice...
Published 2015-01-01“…DMPF-1 selectively inhibited TNF-α-stimulated CC chemokine secretion (RANTES, eotaxin-1, and MCP-1) without any effect upon CXC chemokine (GRO-α and IL-8) secretion. …”
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