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Lichen Sclerosus Atrophicus with Vitiligo in Pediatrics
Published 2021-03-01“…Age expressed in years, sex, race, genital involvement, evolution time in years, associated symptoms, other associated diseases were taken into account: vitiligo, dermatomyositis, scleroderma, lupus erythematosus, type of lesions, morphea, koebner and treatment. …”
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Burden of associated comorbidities in autoimmune rheumatic diseases in Indian population: An interim report based on the Indian rheumatology association database
Published 2022-01-01“…The patients were broadly classified into five based on diagnosed AIRDS namely rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), seronegative spondyloarthropathy (SpA), psoriasis arthritis (PsA), and scleroderma. The prevalence of different comorbidities was compared between the groups using Chi-square or Fischer-exact test for nonparametric data and analysis of variance for continuous variables. …”
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Automatic assessment of nailfold capillaroscopy software: a pilot study
Published 2024-11-01“…Material and methods The study was based on the assessment of 200 capillaroscopic images obtained from patients suffering from systemic sclerosis or scleroderma spectrum diseases and healthy people. Dinolite MEDL4N Pro was used to perform capillaroscopy. …”
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Abnormal Esophageal Scintigraphy Associates With a Distinct Clinical Phenotype in Patients With Systemic Sclerosis
Published 2025-01-01“…University of California Los Angeles Scleroderma Clinical Trials Consortium Gastrointestinal Tract (GIT) 2.0 scores measured GI symptoms, Medsger scores measured physician‐assessed SSc disease severity, and the Composite Autonomic Symptom Score 31 survey evaluated dysautonomia symptoms. …”
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A Case of Subacute Cutaneous Lupus Erythematosus in a Patient with Mixed Connective Tissue Disease: Successful Treatment with Plasmapheresis and Rituximab
Published 2013-01-01“…A 30-year-old woman affected by Mixed Connective Tissue Disease with scleroderma spectrum developed a facial eruption, a clinical and histological characteristic of subacute cutaneous lupus erythematosus (SCLE). …”
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Serum vascular endothelial growth factor levels as a marker of skin thickening, digital ischemia, and interstitial lung disease in systemic sclerosis
Published 2018-01-01“…Methods: Serum VEGF levels were measured in 55 patients with SSC who fulfilled 2013 ACR/EULAR classification criteria for scleroderma and 30 healthy age- and gender-matched controls by ELISA. …”
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Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases
Published 2025-01-01“…Importantly, increased Th17 cells are also found in other fibrotic skin diseases, such as hypertrophic scars and scleroderma, suggesting this represents a broad mechanism for skin fibrosis.ConclusionIn summary, we built a single-cell atlas of fibrotic skin diseases in this study. …”
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Autoimmune Complications after Hematopoietic Stem Cell Transplantation in Children with Nonmalignant Disorders
Published 2014-01-01“…Five (5.4%) patients were diagnosed with scleroderma manifestations, six (6.5%) with vitiligo, six (6.5%) with autoimmune hemolytic anemia (AIHA), six (6.5%) with idiopathic thrombocytopenia, three (3.3%) with mild leucopenia, two (2.2%) with aplastic anemia, two (2.2%) (one boy, one girl) with autoimmune thyroid disease, and one (1.1%) with autoimmune hepatitis. …”
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Does therapy with immunosuppressive drugs improve gastrointestinal symptoms in patients with systemic sclerosis?
Published 2024-07-01“…We aimed to identify an association between immunosuppressive therapy and the the severity of GI symptoms, measured by the University of California at Los Angeles/Scleroderma Clinical Trial Consortium Gastro-Intestinal Tract instrument 2.0 (GIT).Methods We selected patients with SSc who had at least two visits (further referred to as ‘baseline’ and ‘follow-up’) with completed GITs, within an interval of 12±3 months. …”
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Is middle East pain syndrome (MEPS) a variant of fibromyalgia syndrome or a distinct disease?
Published 2025-01-01“…Conclusion Elevated IL-17 levels, non-scleroderma pattern capillaroscopic and enthesopathy findings in both MEPS and FMS patients are strongly supportive that inflammatory mechanisms participate in the pathogenesis of both diseases. …”
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