Improving Mental Health and Well-Being Through the Paradym App: Quantitative Study of Real-World Data by Athina Marina Metaxa, Shaun Liverpool, Mia Eisenstadt, John Pollard, Courtney Carlsson

“…ConclusionsThis real-world data analysis and evaluation provided positive preliminary evidence for the Paradym app’s effectiveness in improving mental health and well-being, supporting its use as a scalable intervention for emotional well-being, with potential applications across diverse populations and settings, and encourages the use of built-in assessments in mental health app research.…”
Get full text

Framework for smartphone-based grape detection and vineyard management using UAV-trained AI by Sergio Vélez, Mar Ariza-Sentís, Mario Triviño, Antonio Carlos Cob-Parro, Miquel Mila, João Valente

“…This study highlights the potential of using smartphone imaging and web applications together, making an effort to integrate these models into a real platform for farmers, offering a practical, affordable, accessible, and scalable solution. While smartphone-based image collection for model training is labour-intensive and costly, incorporating UAV data accelerates the process, facilitating the creation of models that generalise across diverse data sources and platforms. …”
Get full text

Evaluation of a Guided Chatbot Intervention for Young People in Jordan: Feasibility Randomized Controlled Trial by Anne Marijn de Graaff, Rand Habashneh, Sarah Fanatseh, Dharani Keyan, Aemal Akhtar, Adnan Abualhaija, Muhannad Faroun, Ibrahim Said Aqel, Latefa Dardas, Chiara Servili, Mark van Ommeren, Richard Bryant, Kenneth Carswell

“…The World Health Organization (WHO) developed a guided, nonartificial intelligence chatbot intervention called Scalable Technology for Adolescents and youth to Reduce Stress (STARS) to reduce symptoms of depression and anxiety among young people affected by adversity. …”
Get full text

Exploring New Delhi Metallo Beta Lactamases in Klebsiella pneumoniae and Escherichia coli: genotypic vs. phenotypic insights by Noor Ul Ain, Linzy Elton, Zahra Sadouki, Timothy D. McHugh, Saba Riaz

“…This research underscores the utility of lateral flow assays as a practical alternative to resource-intensive genotypic methods, offering a scalable solution for settings with limited laboratory capacity. …”
Get full text

AiGPro: a multi-tasks model for profiling of GPCRs for agonist and antagonist by Rahul Brahma, Sunghyun Moon, Jae-Min Shin, Kwang-Hwi Cho

“…Covering a diverse set of 231 GPCR targets, the platform delivers a robust, scalable solution for advancing GPCR-focused therapeutic development. …”
Get full text

Integrating Videoconferencing Therapist Guidance Into Stepped Care Internet-Delivered Cognitive Behavioral Therapy for Child and Adolescent Anxiety: Noninferiority Randomized Contr... by Sonja March, Susan H Spence, Larry Myers, Martelle Ford, Genevieve Smith, Caroline L Donovan

“…Alternative models of care are required that promote engagement and are effective, accessible, and scalable. ObjectiveThis randomized trial evaluated whether a stepped care approach to ICBT using therapist guidance via videoconferencing for the step-up component (ICBT-SC[VC]) is noninferior to ICBT with full therapist delivery by videoconferencing (ICBT-TG[VC]) for child and adolescent anxiety. …”
Get full text

Mamá Empoderada: study protocol for a pilot trial of a novel parenting and mental health prevention intervention for migrant mothers with young children at the Mexico-US border by Gudelia Rangel, Shira M Goldenberg, Eileen Pitpitan, Kaylee Ramage, Ietza Bojorquez-Chapela, Cecilia Martinez-Torteya, Katherine Rosenblum, Chelsie Hernandez, Monica Alvarez

“…Amid rising population displacement and prolonged and traumatic migration journeys, this study addresses an urgent need for scalable and tailored mental health prevention for MMC in border contexts.Trial registration number NCT06468046.…”
Get full text

Internet-Based Dementia Prevention Intervention (DementiaRisk): Protocol for a Randomized Controlled Trial and Knowledge Translation by Anthony J Levinson, Stephanie Ayers, Sandra Clark, Rebekah Woodburn, Maureen Dobbins, Dante Duarte, Roland Grad, Nick Kates, Sharon Marr, Doug Oliver, Alexandra Papaioannou, Karen Saperson, Henry Siu, Gillian Strudwick, Richard Sztramko, Sarah Neil-Sztramko

“…ConclusionsDementiaRisk is a readily scalable, technology-enhanced solution for dementia prevention education. …”
Get full text

Process evaluation of Project Daire: a food environment intervention that impacted food knowledge, wellbeing and dietary habits of primary school children by Naomi Anderson, Sarah F. Brennan, Fiona Lavelle, Sarah E. Moore, Dilara Olgacher, Amy Junkin, Moira Dean, Michelle C. McKinley, Patrick McCole, Ruth F. Hunter, Laura Dunne, Niamh E. O’Connell, Chris T. Elliott, Danielle McCarthy, Jayne V. Woodside

“…The purpose of this study was to conduct a process evaluation to evaluate DAIRE implementation, mechanisms of impact (MOI) and context to elucidate trial results, and inform scalable implementation of the DAIRE approach for successful future rollout. …”
Get full text

Subtyping Social Determinants of Health in the "All of Us" Program: Network Analysis and Visualization Study by Suresh K Bhavnani, Weibin Zhang, Daniel Bao, Mukaila Raji, Veronica Ajewole, Rodney Hunter, Yong-Fang Kuo, Susanne Schmidt, Monique R Pappadis, Elise Smith, Alex Bokov, Timothy Reistetter, Shyam Visweswaran, Brian Downer

“…However, the high degree of systematic missingness requires repeating the analysis as the data become more complete by using our generalizable and scalable machine learning code available on the All of Us workbench.…”
Get full text

Investigating the Efficacy of the Web-Based Common Elements Toolbox (COMET) Single-Session Interventions in Improving UK University Student Well-Being: Randomized Controlled Trial by Jeffrey Lambert, Maria Loades, Noah Marshall, Nina Higson-Sweeney, Stella Chan, Arif Mahmud, Victoria Pile, Ananya Maity, Helena Adam, Beatrice Sung, Melanie Luximon, Keren MacLennan, Clio Berry, Paul Chadwick

“…Single-session interventions (SSIs) are designed to be scalable and accessible, delivering core evidence-based intervention components within a one-off encounter. …”
Get full text

Women's experiences and acceptability of self-administered, home delivered, intravaginal 5-Fluorouracil cream for cervical precancer treatment in Kenya by Konyin Adewumi, Aparna Ghosh Kachoria, Everlyn Adoyo, Mercy Rop, Mercy Rop, Antony Owaya, Jennifer H. Tang, Jennifer H. Tang, Lisa Rahangdale, Lisa Rahangdale, Lisa Rahangdale, Chemtai Mungo, Chemtai Mungo, Chemtai Mungo

“…In low-and middle-income countries (LMICs) where most cervical cancer cases occur, access to precancer treatment is severely limited. Scalable solutions like self-administered topical therapies can help close this gap. …”
Get full text

Psychosocial risks and mental health of health and social care workers in the context of the COVID-19 pandemic by Nadia Vilahur Chiaraviglio

“…Furthermore, it systematically maps and assesses the range of interventions conducted since 2020 to increase psychosocial wellbeing and prevent and manage mental health problems in the sector, to offer practical guidance and a range of scalable examples to workplaces.  In summary, widescale and long-term systemic interventions are needed, combining organizational and individual focused approaches to protect workers from the challenges for their mental wellbeing posed by complex and changing work environments. …”
Get full text